Research Topics
Genomes and Genes | C PaganoSummaryAffiliation: University of Padova Country: Italy Publications
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Detail Information
Publications
The Italian National Survey for Prader-Willi syndrome: an epidemiologic studyGraziano Grugni
Italian Auxological Institute Foundation, Research Institute, Verbania, Italy
Am J Med Genet A 146:861-72. 2008..Overall, there was no increase in number of deaths during GH treatment, suggesting that GH administration in patients with PWS, as a group, does not increase the risk of death...
Plasma adiponectin is decreased in nonalcoholic fatty liver diseaseClaudio Pagano
Endocrine Metabolic Laboratory, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Eur J Endocrinol 152:113-8. 2005..We therefore conducted this study to assess the relationship between plasma adiponectin and nonalcoholic fatty liver disease to explore its role in the pathogenesis of this disease...
Role of insulin and free fatty acids in the regulation of ob gene expression and plasma leptin in normal ratsClaudio Pagano
Endocrine Metabolic Library, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Obes Res 12:2062-9. 2004..In this study, we evaluated whether leptin secretion induced by FFA is due directly to an increased FFA availability or whether it is mediated by insulin levels...
Increased serum resistin in adults with prader-willi syndrome is related to obesity and not to insulin resistanceClaudio Pagano
Endocrine Metabolic Laboratory, Department of Medical and Surgical Sciences, Biotechnology Centre, University of Padua, Italy
J Clin Endocrinol Metab 90:4335-40. 2005..The discovery of several adipokines with relevant effects on insulin resistance and cardiovascular complications of metabolic syndrome offered new tools of investigation of insulin resistance in PWS...
Increased serum resistin in nonalcoholic fatty liver disease is related to liver disease severity and not to insulin resistanceClaudio Pagano
Department of Medical and Surgical Sciences, University of Padova, Via Ospedale 105, 35100 Padova, Italy
J Clin Endocrinol Metab 91:1081-6. 2006..The recently discovered hormone resistin is linked to the development of insulin resistance, but direct evidence of resistin levels in humans with nonalcoholic fatty liver disease (NAFLD) is lacking...
Reduced plasma visfatin/pre-B cell colony-enhancing factor in obesity is not related to insulin resistance in humansClaudio Pagano
Endocrine Metabolic Laboratory, Department of Medical and Surgical Sciences, University of Padua, Via Ospedale 105, 35100 Padua, Italy
J Clin Endocrinol Metab 91:3165-70. 2006....
Heart lipid accumulation in obese non-diabetic rats: effect of weight lossClaudio Pagano
Endocrine Metabolic Unit, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale 105, 35100 Padova, Italy
Nutr Metab Cardiovasc Dis 18:189-97. 2008..The aim of this study was to investigate lipid content and expression of genes involved in lipid metabolism, in lean and obese non-diabetic rats and in obese rats undergoing food restriction and weight loss...
The endogenous cannabinoid system stimulates glucose uptake in human fat cells via phosphatidylinositol 3-kinase and calcium-dependent mechanismsClaudio Pagano
Endocrine Metabolic Laboratory, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale 105, 35100 Padova, Italy
J Clin Endocrinol Metab 92:4810-9. 2007..Adipose tissue endocannabinoids may produce metabolic and endocrine effects, but very few data are available in human adipose tissue and in primary human fat cells...
Endocannabinoids, adipose tissue and lipid metabolismC Pagano
Endocrine Metabolic Laboratory, Clinica Medica 3, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
J Neuroendocrinol 20:124-9. 2008..This review will focus on the role of endocannabinoids in adipose tissue metabolism, adipokine production and interactions between endocannabinoids and peroxisome proliferator activated receptors during adipogenesis...
Resistin and adiponectin expression in visceral fat of obese rats: effect of weight lossGabriella Milan
Endocrine Metabolic Laboratory, Internal Medicine, Department of Medical and Surgical Sciences, University of Padova, 35128 Padova, Italy
Obes Res 10:1095-103. 2002..Some of these adipocytokines are also present in the immune system, thus suggesting an intriguing functional connection...
Increased adipogenic conversion of muscle satellite cells in obese Zucker ratsA Scarda
Endocrine Metabolic Laboratory, Internal Medicine, Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
Int J Obes (Lond) 34:1319-27. 2010..We investigated the myogenic differentiation of SCs and the adipogenic potential of both preadipocytes and SCs from genetically obese Zucker rats (fa/fa), focusing on the role of Wnt signaling in these differentiation processes...
Substrate competition and insulin action in animal modelsR Vettor
Department of Medical and Surgical Sciences, University of Padova, Italy
Int J Obes Relat Metab Disord 24:S22-4. 2000..In obesity, lactate and FFA overproduction from visceral fat may therefore play a synergic role in reducing insulin sensitivity...
Molecular and morphometric description of adipose tissue during weight changes: a quantitative tool for assessment of tissue textureClaudio Pagano
Department of Medical and Surgical Sciences, Endocrine Metabolic Laboratory, University of Padova, Via Ospedale 105, Padova, Italy
Int J Mol Med 14:897-902. 2004..Moreover, image analysis system seems a reliable quantitative tool for assessment of adipose tissue texture...
Rosiglitazone modifies the adipogenic potential of human muscle satellite cellsP De Coppi
Paediatric Oncohaematology, Stem Cell Transplantation Unit, University of Padua, Via Ospedale 105, 35128 Padua, Italy
Diabetologia 49:1962-73. 2006..This could partially counteract the worsening effect of intermuscular adipose tissue depots on muscle insulin sensitivity...
The role of the endocannabinoid system in lipogenesis and fatty acid metabolismRoberto Vettor
Internal Medicine 3, Endocrine Metabolic Laboratory, Department of Medical and Surgical Sciences, University of Padova, Via Ospedale 105, 35128 Padova, Italy
Best Pract Res Clin Endocrinol Metab 23:51-63. 2009..This review focuses on the role of ECs in adipose tissue metabolism, adipokine production, and interactions between ECs and peroxisome proliferator-activated receptors (PPARs) during adipogenesis...
Changes in muscle myostatin expression in obese subjects after weight lossG Milan
Department of Medical and Surgical Sciences, University of Padova, Italy
J Clin Endocrinol Metab 89:2724-7. 2004..Our data suggest that myostatin might represent an important regulator of skeletal muscle size also in conditions of food restriction in obese subjects...
The cannabinoid system and male reproductive functionsM Rossato
Endocrine Metabolic Laboratory, Clinica Medica 3, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
J Neuroendocrinol 20:90-3. 2008..In the present paper, we briefly review the effects of cannabinoids and endocannabinoids, a particular group of endogenously produced cannabinoids, on male reproductive function...
Moderate alcohol consumption, glucose metabolism and lipolysis: the effect on adiponectin and tumor necrosis factor alphaA Avogaro
Division of Metabolic Diseases, University of Padua Medical School, Padua, Italy
J Endocrinol Invest 26:1213-8. 2003..Further studies are needed to clarify the antilipolytic effect of moderate alcohol intake...
Neuroendocrine regulation of eating behaviorR Vettor
Internal Medicine, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
J Endocrinol Invest 25:836-54. 2002..Given the aim of this review, we will focus on the major structures involved in the control of energy balance...
Effect of sibutramine on weight management and metabolic control in type 2 diabetes: a meta-analysis of clinical studiesRoberto Vettor
Department of Medical and Surgical Sciences, Endocrine Metabolic Laboratory, University of Padua, Via Ospedale 105, 35128 Padua, Italy
Diabetes Care 28:942-9. 2005..The aim of this study was to provide a comprehensive meta-analysis of randomized controlled clinical studies on the effects of sibutramine on weight loss and glycemic control in obese subjects with type 2 diabetes...
Insulin-like factor 3 as a marker of testicular function in obese menCarlo Foresta
Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Via Gabelli 63, Padova, Italy
Clin Endocrinol (Oxf) 71:722-6. 2009..To better evaluate the hormonal function of the testis in obese men, we analysed their INSL3 plasma levels and compared them with the obesity status and the other reproductive hormones...
HYTAD1-p20: a new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancerAntonio Rosato
Department of Oncology and Surgical Sciences, Oncology Section, University of Padua, Padua, Italy
Urol Oncol 24:207-15. 2006..To report the development of a new water-soluble paclitaxel-hyaluronic acid bioconjugate, HYTAD1-p20, for intravesical treatment of superficial bladder cancer...
Effect of glucocorticoids on adiponectin: a study in healthy subjects and in Cushing's syndromeFrancesco Fallo
Department of Medical and Surgical Sciences, University of Padova, Italy
Eur J Endocrinol 150:339-44. 2004..We evaluated first the acute effect of i.v. glucocorticoids on adiponectin in normal subjects and secondly plasma adiponectin levels in a series of patients with Cushing's syndrome compared with controls...
Neuroendocrine regulation of feedingR Vettor
Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
Minerva Endocrinol 28:155-67. 2003..This review will focus on the central and peripheral factors thought to be involved in the neuroendocrine control of feeding behavior...
Here, there and everywhere: the endocannabinoid systemRoberto Vettor
J Neuroendocrinol 20:iv-vi. 2008
Adiponectin levels in women with polycystic ovary syndromeFrancesco Orio
Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, 80131 Naples, Italy
J Clin Endocrinol Metab 88:2619-23. 2003..They further suggest that insulin sensitivity per se probably does not play any pivotal role in the control of adiponectin levels in PCOS women...
A real-time PCR approach to evaluate adipogenic potential of amniotic fluid-derived human mesenchymal stem cellsPaola de Gemmis
BIRD Europe Institute, Vicenza, Italy
Stem Cells Dev 15:719-28. 2006..We tested our experimental model with two different media. Understanding in vivo adipogenesis mechanisms will shed light on the pathophysiology of many diseases...
Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytesLaura Tedesco
Integrated Laboratories Network, Center for Study and Research on Obesity, Department of Pharmacology, Chemotherapy and Medical Toxicology, School of Medicine, Milan University, Milan, Italy
Diabetes 57:2028-36. 2008..This study was undertaken to test whether CB1 receptor blockade increases the espression of eNOS and mitochondrial biogenesis in white adipocytes...
Lipohypertrophy in acromegaly induced by the new growth hormone receptor antagonist pegvisomantPietro Maffei
Ann Intern Med 145:310-2. 2006
