Giulia Ottaviani

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Sudden and unexpected infant death due to an hemangioendothelioma located in the medulla oblongata
    L Matturri
    Istitute of Anatomical Pathology, University of Milano, Milano, 20122, Italy
    Adv Clin Path 3:29-33. 1999
  2. pmc Hypoplasia and neuronal immaturity of the hypoglossal nucleus in sudden infant death
    G Ottaviani
    Institute of Pathology, Lino Rossi Research Centre for the study and prevention of unexpected perinatal death and SIDS, University of Milan, Italy
    J Clin Pathol 59:497-500. 2006
  3. doi request reprint Sudden infant and perinatal unexplained death: are we moving forward yet?
    Giulia Ottaviani
    Dipartimento di Scienze Materno Infantili, Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli Regina Elena, Universita degli Studi di Milano, Milan, Italy
    Cardiovasc Pathol 20:302-6. 2011
  4. ncbi request reprint Sudden death due to lymphomatous infiltration of the cardiac conduction system
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Via della Commenda, 19 20122 Milan, Italy
    Cardiovasc Pathol 12:77-81. 2003
  5. ncbi request reprint Segmental cement extraction system (SEG-CES) and the Ilizarov method in limb salvage procedure after total knee cemented prosthesis removal in a former osteosarcoma patient
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Milan, Italy
    Knee Surg Sports Traumatol Arthrosc 13:557-63. 2005
  6. doi request reprint Histopathology of the cardiac conduction system in sudden intrauterine unexplained death
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Lino Rossi Research Center, Milan, Italy
    Cardiovasc Pathol 17:146-55. 2008
  7. ncbi request reprint Crib death: further support for the concept of fatal cardiac electrical instability as the final common pathway
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy
    Int J Cardiol 92:17-26. 2003
  8. doi request reprint Fibromuscular hyperplasia of the pulmonary artery in sudden infant and perinatal unexpected death
    Giulia Ottaviani
    Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Milan, Italy
    Cardiovasc Pathol 18:223-30. 2009
  9. doi request reprint Infant and perinatal pulmonary hypoplasia frequently associated with brainstem hypodevelopment
    Giulia Ottaviani
    Lino Rossi Research Center for the study and prevention of the unexpected perinatal death and SIDS, University of Milan, Milan, Italy
    Virchows Arch 454:451-6. 2009
  10. doi request reprint Functional, psychosocial and professional outcomes in long-term survivors of lower-extremity osteosarcomas: amputation versus limb salvage
    Giulia Ottaviani
    Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Cancer Treat Res 152:421-36. 2009

Collaborators

Detail Information

Publications55

  1. ncbi request reprint Sudden and unexpected infant death due to an hemangioendothelioma located in the medulla oblongata
    L Matturri
    Istitute of Anatomical Pathology, University of Milano, Milano, 20122, Italy
    Adv Clin Path 3:29-33. 1999
    ..Necroscopy studies of sudden infant death should always include an accurate histological examination of the medulla oblongata on serial sections but seldom do...
  2. pmc Hypoplasia and neuronal immaturity of the hypoglossal nucleus in sudden infant death
    G Ottaviani
    Institute of Pathology, Lino Rossi Research Centre for the study and prevention of unexpected perinatal death and SIDS, University of Milan, Italy
    J Clin Pathol 59:497-500. 2006
    ..Her sudden death offered a unique insight into the possible role of delayed neuronal maturation and hypoplasia of the hypoglossal nucleus in representing a likely morphological substrate of sudden death...
  3. doi request reprint Sudden infant and perinatal unexplained death: are we moving forward yet?
    Giulia Ottaviani
    Dipartimento di Scienze Materno Infantili, Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli Regina Elena, Universita degli Studi di Milano, Milan, Italy
    Cardiovasc Pathol 20:302-6. 2011
    ..Recent anatomical, pathological, and bacteriological studies in SIDS confirm that the multidisciplinary approach provides the best approach to the challenging problems of SIDS and sudden unexplained perinatal death...
  4. ncbi request reprint Sudden death due to lymphomatous infiltration of the cardiac conduction system
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Via della Commenda, 19 20122 Milan, Italy
    Cardiovasc Pathol 12:77-81. 2003
    ..This case illustrates the utility of examination of the cardiac conduction system in necroscopy studies of sudden death...
  5. ncbi request reprint Segmental cement extraction system (SEG-CES) and the Ilizarov method in limb salvage procedure after total knee cemented prosthesis removal in a former osteosarcoma patient
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Milan, Italy
    Knee Surg Sports Traumatol Arthrosc 13:557-63. 2005
    ..The successful prosthesis removal performed in this patient allowed us to perform an external fixation with bone lengthening and reconstruction by the Ilizarov method...
  6. doi request reprint Histopathology of the cardiac conduction system in sudden intrauterine unexplained death
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Lino Rossi Research Center, Milan, Italy
    Cardiovasc Pathol 17:146-55. 2008
    ..It remains poorly understood and incompletely examined both morphologically and functionally. The aim of this work is to examine the likely role of cardiac conduction system in relation to sudden and unexplained fetal death...
  7. ncbi request reprint Crib death: further support for the concept of fatal cardiac electrical instability as the final common pathway
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy
    Int J Cardiol 92:17-26. 2003
    ....
  8. doi request reprint Fibromuscular hyperplasia of the pulmonary artery in sudden infant and perinatal unexpected death
    Giulia Ottaviani
    Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Milan, Italy
    Cardiovasc Pathol 18:223-30. 2009
    ....
  9. doi request reprint Infant and perinatal pulmonary hypoplasia frequently associated with brainstem hypodevelopment
    Giulia Ottaviani
    Lino Rossi Research Center for the study and prevention of the unexpected perinatal death and SIDS, University of Milan, Milan, Italy
    Virchows Arch 454:451-6. 2009
    ..8%). In 47.1% of cases, pulmonary hypoplasia was associated with brainstem hypodevelopment...
  10. doi request reprint Functional, psychosocial and professional outcomes in long-term survivors of lower-extremity osteosarcomas: amputation versus limb salvage
    Giulia Ottaviani
    Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Cancer Treat Res 152:421-36. 2009
    ..A number of long-term survivors also achieved high ranking in the professional and commercial work place. These positive aspects should be recognized and emphasized to patients and their parents when discussing the outcome...
  11. doi request reprint Sudden unexpected death in young athletes
    Giulia Ottaviani
    Lino Rossi Research Center, and daggerInstitute of Pediatrics and Neonatology, University of Milan, Italy
    Am J Forensic Med Pathol 29:337-9. 2008
    ..In addition, enquiry should be made into the concomitant presence of a smoking habit or of passive smoke exposure...
  12. ncbi request reprint Histopathology of the cardiac conduction system in a case of metastatic pancreatic ductal adenocarcinoma
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
    Anticancer Res 22:3029-32. 2002
    ....
  13. doi request reprint The epidemiology of osteosarcoma
    Giulia Ottaviani
    Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Cancer Treat Res 152:3-13. 2009
    ..Tumor staging, presence of metastases, local recurrence, chemotherapy regimen, anatomic location, size of the tumor, and percentage of tumor cells destroyed after neoadjuvant chemotherapy have effects on the outcome...
  14. doi request reprint The etiology of osteosarcoma
    Giulia Ottaviani
    Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Cancer Treat Res 152:15-32. 2009
    ..Osteosarcoma has also been associated with the use of intravenous radium and Thorotrast. Exposure to alkylating agents may also contribute to its development ,and it is apparently independent of the administration of radiotherapy...
  15. ncbi request reprint Adverse effects of prenatal tobacco smoke exposure on biological parameters of the developing brainstem
    Anna Maria Lavezzi
    Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and Sudden Infant Death Syndrome SIDS, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
    Neurobiol Dis 20:601-7. 2005
    ....
  16. ncbi request reprint Biopathology of the dentate-olivary complex in sudden unexplained perinatal death and sudden infant death syndrome related to maternal cigarette smoking
    Anna Maria Lavezzi
    Institute of Pathology, Lino Rossi Research Center, University of Milan, Milan, Italy
    Neurol Res 29:525-32. 2007
    ..The present study was aimed to evaluate the possible presence of cytohistologic and/or biologic modifications of the human dentate-olivary complex in sudden unexplained perinatal and infant deaths...
  17. ncbi request reprint Techniques and criteria in pathologic and forensic-medical diagnostics in sudden unexpected infant and perinatal death
    Luigi Matturri
    Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Milan, Italy
    Am J Clin Pathol 124:259-68. 2005
    ..The data and arguments presented herein provide a brief survey tending to open, rather than conclude, a far-reaching subject and to motivate medicolegal specialists and pathologists to perform more in-depth study...
  18. ncbi request reprint Cytoarchitectural organization of the parabrachial/Kölliker-Fuse complex in man
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
    Brain Dev 26:316-20. 2004
    ..The neuronal maturation of these nuclei was seen to occur between the 35th and the 36th gestational weeks...
  19. ncbi request reprint Biology of the smooth muscle cells in human atherosclerosis
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Italy
    APMIS 113:112-21. 2005
    ..The observation in some cases of chromosome 7 alterations, markers of tumorigenesis, suggests the possible transformation of an advanced atherosclerotic plaque into a neoplastic-like process...
  20. ncbi request reprint Analysis of the human locus coeruleus in perinatal and infant sudden unexplained deaths. Possible role of the cigarette smoking in the development of this nucleus
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
    Brain Res Dev Brain Res 154:71-80. 2005
    ....
  21. ncbi request reprint Early atherosclerotic lesions in infancy: role of parental cigarette smoking
    Luigi Matturri
    Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death of term fetus stillbirth and neonatal and Sudden Infant Death Syndrome SIDS, University of Milan, Milan, Italy
    Virchows Arch 447:74-80. 2005
    ..We suggest that the oxidants present in the gas phase of the parental cigarette smoke pass through the endothelium and induce at first the c-fos gene activation and subsequently the PCNA positivity, that is, a proliferative process...
  22. ncbi request reprint Ontogenesis of human cerebellar cortex and biopathological characterization in sudden unexplained fetal and infant death
    Anna Maria Lavezzi
    Institute of Pathology, Lino Rossi Research Center, University of Milan, Via della Commenda, 19, Milan, 20122, Italy
    Virchows Arch 450:31-40. 2007
    ..Maternal smoking is increasingly being demonstrated to be one of the main contributors to developmental neurological alterations in the offspring...
  23. pmc Psychosocial and functional outcomes in long-term survivors of osteosarcoma: a comparison of limb-salvage surgery and amputation
    Rhonda S Robert
    Division of Pediatrics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Pediatr Blood Cancer 54:990-9. 2010
    ..We hypothesized there to be neither psychosocial nor functional outcome differences between groups...
  24. ncbi request reprint Study of the brainstem, particularly the arcuate nucleus, in sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death (SIUD)
    Luigi Matturri
    Institute of Pathology, University of Milan, Italy
    Am J Forensic Med Pathol 25:44-8. 2004
    ..The simplified examination of the brainstem makes it possible to evaluate the structures, examining 3 specific levels, defined by morphologic reference points...
  25. ncbi request reprint Guidelines for neuropathologic diagnostics of perinatal unexpected loss and sudden infant death syndrome (SIDS): a technical protocol
    Luigi Matturri
    Institute of Pathology, University of Milan, Via della Commenda, Milan, Italy
    Virchows Arch 452:19-25. 2008
    ....
  26. ncbi request reprint Alterations of biological features of the cerebellum in sudden perinatal and infant death
    Anna Maria Lavezzi
    Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Italy
    Curr Mol Med 6:429-35. 2006
    ....
  27. ncbi request reprint Hypoplasia of the parabrachial/kölliker-fuse complex in perinatal death
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Milan, Italy
    Biol Neonate 86:92-7. 2004
    ..Such hypoplasia was associated with severe hypoplasia of the arcuate nucleus and pulmonary hypoplasia...
  28. ncbi request reprint Multifocal cardiac Purkinje cell tumor in infancy
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
    Europace 6:138-41. 2004
    ..Necroscopy studies of sudden infant death should always include an accurate histological examination of the cardiac conduction system and brainstem using serial sections...
  29. pmc Involvement of the EN-2 gene in normal and abnormal development of the human arcuate nucleus
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Italy
    Int J Exp Pathol 86:25-31. 2005
    ..In conclusion, we support the role of the EN-2 gene in the normal neuronal development and in the anatomic organization of the human ArcN as well as the possible existence of EN-2 mutations related to hypoplasia of this nucleus...
  30. ncbi request reprint Hypoplasia of the arcuate nucleus and maternal smoking during pregnancy in sudden unexplained perinatal and infant death
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Italy
    Neuropathology 24:284-9. 2004
    ....
  31. ncbi request reprint Preliminary study on the cytoarchitecture of the human parabrachial/Kölliker-fuse complex, with reference to sudden infant death syndrome and sudden intrauterine unexplained death
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Via della Commenda 19, 20122, Milan, Italy
    Pediatr Dev Pathol 7:171-9. 2004
    ....
  32. ncbi request reprint Unexpected perinatal death and sudden infant death syndrome (SIDS): anatomopathologic and legal aspects
    Luigi Matturri
    Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and Sudden Infant Death Syndrome SIDS, University of Milan, Milan, Italy
    Am J Forensic Med Pathol 26:155-60. 2005
    ....
  33. ncbi request reprint Histological and biological developmental characterization of the human cerebellar cortex
    Anna Maria Lavezzi
    Institute of Pathology, Lino Rossi Research Center, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
    Int J Dev Neurosci 24:365-71. 2006
    ..Consequently, we can diagnose delayed or altered processes of differentiation during the development of the human cerebellar cortex...
  34. ncbi request reprint Maternal smoking and sudden infant death syndrome: epidemiological study related to pathology
    Luigi Matturri
    Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
    Virchows Arch 449:697-706. 2006
    ..A significant relation was found between maternal smoke and brainstem alterations...
  35. ncbi request reprint Sudden unexpected death of a term fetus in an anticardiolipin-positive mother
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Italy
    Am J Perinatol 21:79-83. 2004
    ....
  36. ncbi request reprint Identification of neurons responding to hypoxia in sudden infant death syndrome
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Milan, Italy
    Pathol Int 53:769-74. 2003
    ..Our results support the respiratory theory of SIDS...
  37. ncbi request reprint Sudden infant death syndrome "gray zone" disclosed only by a study of the brain stem on serial sections
    Giulia Ottaviani
    University of Milan, Milan, Italy
    J Perinat Med 33:165-9. 2005
    ....
  38. ncbi request reprint Early atherosclerotic lesions of the cardiac conduction system arteries in infants
    Luigi Matturri
    Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy
    Cardiovasc Pathol 13:276-81. 2004
    ..In particular, to the best of our knowledge, none has considered the lesions of the cardiac conduction arteries as an initial stage of atherosclerosis...
  39. ncbi request reprint Association between pulmonary hypoplasia and hypoplasia of arcuate nucleus in stillbirth
    Luigi Matturri
    Institute of Pathology, University of Milan, Italy
    J Perinatol 23:328-32. 2003
    ..To investigate lung development and to correlate pulmonary hypoplasia with hypoplasia of the arcuate nucleus in stillbirths...
  40. ncbi request reprint Sudden infant death syndrome (SIDS) shortly after hexavalent vaccination: another pathology in suspected SIDS?
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Via della Commenda 19, Milan 20122, Italy
    Virchows Arch 448:100-4. 2006
    ..Any case of sudden unexpected death occurring perinatally and in infancy, especially soon after a vaccination, should always undergo a full necropsy study according to our guidelines...
  41. ncbi request reprint Pathogenesis of early atherosclerotic lesions in infants
    Luigi Matturri
    Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy
    Pathol Res Pract 200:403-10. 2004
    ..The lesions appear to be larger and more diffuse when both these atherogenic factors are present...
  42. ncbi request reprint Involvement of somatostatin in breathing control before and after birth, and in perinatal and infant sudden unexplained death
    Anna Maria Lavezzi
    Institute of Pathology, University of Milan, Italy
    Folia Neuropathol 42:59-65. 2004
    ....
  43. ncbi request reprint Expression of apoptosis and proliferating cell nuclear antigen (PCNA) in the cardiac conduction system of crib death (SIDS)
    L Matturri
    Istituto di Anatomia Patologica, Universita degli Studi di Milano, Via della Commenda, 19 20122 Milano, Italy
    Adv Clin Path 5:79-86. 2001
    ..The AI was higher in the AVN, HB and the initial tract of bundle branches than in the common myocardium (p<0.05; Student's t test)...
  44. ncbi request reprint Intimal preatherosclerotic thickening of the coronary arteries in human fetuses of smoker mothers
    L Matturri
    Institute of Pathology, State University of Milan, Via della Commenda 19, 20122 Milan, Italy
    J Thromb Haemost 1:2234-8. 2003
    ..Many studies have described the development of preatherosclerotic coronary artery lesions in infancy. The observations reported in the literature regarding the fetal origin of coronary artery lesions are rare and controversial...
  45. ncbi request reprint Role of somatostatin and apoptosis in breathing control in sudden perinatal and infant unexplained death
    A M Lavezzi
    Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and Sudden Infant Death Syndrome, Institute of Pathology, University of Milan, Italy
    Clin Neuropathol 23:304-10. 2004
    ..To obtain basic information about the expression of somatostatin in the human central nervous system and, in particular, to evaluate its possible involvement in unexplained perinatal and in sudden infant death syndrome...
  46. ncbi request reprint Sudden Infant Death Syndrome (SIDS): a study of cardiac conduction system
    L Matturri
    Institute of Pathology, University of Milan, Milan, Italy
    Cardiovasc Pathol 9:137-45. 2000
    ..These data suggest the need for an accurate approach and examination of the cardiac conduction system in all cases of sudden death in infancy..
  47. ncbi request reprint Autoptic examination in sudden infant death syndrome and sudden intrauterine unexpected death: proposal of a national law
    L Matturri
    Institute of Pathology, University of Milan, Milan, Italy
    J Matern Fetal Neonatal Med 16:43-5. 2004
    ..The objectives of this law include, in article 4, widespread informative and preventive campaigns and continuous formation of programs for medical personnel...
  48. ncbi request reprint Clinical and pathologic study of two siblings with osteosarcoma
    Giulia Ottaviani
    Institute of Pathology, University of Milan, Milano, Italy
    Med Pediatr Oncol 38:62-4. 2002
  49. ncbi request reprint Prognostic significance of different biomarkers (DNA content, PCNA, karyotype) in colorectal adenomas
    Anna Maria Lavezzi
    Department of Pathology, University of Milan, Italy
    Anticancer Res 22:2077-81. 2002
    ..It was concluded that the combination of some biomarkers (additional chromosomes 11, high PCNA and DNA indices) may allow identification of more aggressive colorectal adenomas with increased ability to undergo malignant transformation...
  50. pmc Sudden infant death triggered by dive reflex
    L Matturri
    Lino Rossi Research Centre for the study and prevention of unexpected perinatal death and sudden infant death syndrome SIDS, Institute of Pathology, University of Milan, 20122 Italy
    J Clin Pathol 58:77-80. 2005
    ..The possible role of parental cigarette smoking in the pathogenesis of arcuate nucleus hypoplasia and early coronary atherosclerotic lesions is also discussed...
  51. ncbi request reprint Cardiac massage in infants
    Luigi Matturri
    Intensive Care Med 29:1199-200. 2003
  52. pmc Perinatal and infant early atherosclerotic coronary lesions
    Jose Milei
    Instituto de Investigaciones Cardiologicas, University of Buenos Aires CONICET, Buenos Aires, Argentina
    Can J Cardiol 24:137-41. 2008
    ..Because the fetal origin of coronary artery lesions is controversial, early atherosclerotic coronary artery lesions in late fetal stillborns and infants, as well as the possible atherogenic role of maternal cigarette smoking, were studied...
  53. ncbi request reprint Unexpected sudden death related to medullary brain lesions
    Luigi Matturri
    Acta Neuropathol 109:554-5. 2005
  54. ncbi request reprint Treatment of massive tibial bone loss due to chronic draining osteomyelitis: fibula transport using the Ilizarov frame
    Maurizio A Catagni
    Department of Orthopedics and Ilizarov Unit, Alessandro Manzoni Hospital, Via Dell Eremo 9 11, 23900 Lecco, Italy
    Orthopedics 30:608-11. 2007
    ..This article affirms the value of the application of the Ilizarov frame for gradual transport of the ipsilateral fibula to replace massive tibial bone loss following chronic refractory osteomyelitis...
  55. ncbi request reprint Medial fibula transport with the Ilizarov frame to treat massive tibial bone loss
    Maurizio A Catagni
    Department of Orthopedics and Ilizarov Unit, Alessandro Manzoni Hospital, Lecco, Italy
    Clin Orthop Relat Res 448:208-16. 2006
    ..LEVEL OF EVIDENCE: Therapeutic Study, Level IV (case series). See the Guidelines for Authors for a complete description of levels of evidence...