Research Topics
Genomes and GenesSpecies | Giulia OttavianiSummaryAffiliation: University of Milan Country: Italy Publications
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Detail Information
Publications
Sudden and unexpected infant death due to an hemangioendothelioma located in the medulla oblongataL Matturri
Istitute of Anatomical Pathology, University of Milano, Milano, 20122, Italy
Adv Clin Path 3:29-33. 1999..Necroscopy studies of sudden infant death should always include an accurate histological examination of the medulla oblongata on serial sections but seldom do...
Hypoplasia and neuronal immaturity of the hypoglossal nucleus in sudden infant deathG Ottaviani
Institute of Pathology, Lino Rossi Research Centre for the study and prevention of unexpected perinatal death and SIDS, University of Milan, Italy
J Clin Pathol 59:497-500. 2006..Her sudden death offered a unique insight into the possible role of delayed neuronal maturation and hypoplasia of the hypoglossal nucleus in representing a likely morphological substrate of sudden death...
Sudden death due to lymphomatous infiltration of the cardiac conduction systemGiulia Ottaviani
Institute of Pathology, University of Milan, Via della Commenda, 19 20122 Milan, Italy
Cardiovasc Pathol 12:77-81. 2003..This case illustrates the utility of examination of the cardiac conduction system in necroscopy studies of sudden death...
Sudden infant and perinatal unexplained death: are we moving forward yet?Giulia Ottaviani
Dipartimento di Scienze Materno Infantili, Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli Regina Elena, Universita degli Studi di Milano, Milan, Italy
Cardiovasc Pathol 20:302-6. 2011..Recent anatomical, pathological, and bacteriological studies in SIDS confirm that the multidisciplinary approach provides the best approach to the challenging problems of SIDS and sudden unexplained perinatal death...
Segmental cement extraction system (SEG-CES) and the Ilizarov method in limb salvage procedure after total knee cemented prosthesis removal in a former osteosarcoma patientGiulia Ottaviani
Institute of Pathology, University of Milan, Milan, Italy
Knee Surg Sports Traumatol Arthrosc 13:557-63. 2005..The successful prosthesis removal performed in this patient allowed us to perform an external fixation with bone lengthening and reconstruction by the Ilizarov method...
Histopathology of the cardiac conduction system in sudden intrauterine unexplained deathGiulia Ottaviani
Institute of Pathology, University of Milan, Lino Rossi Research Center, Milan, Italy
Cardiovasc Pathol 17:146-55. 2008..It remains poorly understood and incompletely examined both morphologically and functionally. The aim of this work is to examine the likely role of cardiac conduction system in relation to sudden and unexplained fetal death...
Crib death: further support for the concept of fatal cardiac electrical instability as the final common pathwayGiulia Ottaviani
Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy
Int J Cardiol 92:17-26. 2003....
Fibromuscular hyperplasia of the pulmonary artery in sudden infant and perinatal unexpected deathGiulia Ottaviani
Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Milan, Italy
Cardiovasc Pathol 18:223-30. 2009....
Infant and perinatal pulmonary hypoplasia frequently associated with brainstem hypodevelopmentGiulia Ottaviani
Lino Rossi Research Center for the study and prevention of the unexpected perinatal death and SIDS, University of Milan, Milan, Italy
Virchows Arch 454:451-6. 2009..8%). In 47.1% of cases, pulmonary hypoplasia was associated with brainstem hypodevelopment...
Functional, psychosocial and professional outcomes in long-term survivors of lower-extremity osteosarcomas: amputation versus limb salvageGiulia Ottaviani
Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
Cancer Treat Res 152:421-36. 2009..A number of long-term survivors also achieved high ranking in the professional and commercial work place. These positive aspects should be recognized and emphasized to patients and their parents when discussing the outcome...
Sudden unexpected death in young athletesGiulia Ottaviani
Lino Rossi Research Center, and daggerInstitute of Pediatrics and Neonatology, University of Milan, Italy
Am J Forensic Med Pathol 29:337-9. 2008..In addition, enquiry should be made into the concomitant presence of a smoking habit or of passive smoke exposure...
Histopathology of the cardiac conduction system in a case of metastatic pancreatic ductal adenocarcinomaGiulia Ottaviani
Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
Anticancer Res 22:3029-32. 2002....
The epidemiology of osteosarcomaGiulia Ottaviani
Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
Cancer Treat Res 152:3-13. 2009..Tumor staging, presence of metastases, local recurrence, chemotherapy regimen, anatomic location, size of the tumor, and percentage of tumor cells destroyed after neoadjuvant chemotherapy have effects on the outcome...
The etiology of osteosarcomaGiulia Ottaviani
Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
Cancer Treat Res 152:15-32. 2009..Osteosarcoma has also been associated with the use of intravenous radium and Thorotrast. Exposure to alkylating agents may also contribute to its development ,and it is apparently independent of the administration of radiotherapy...
Adverse effects of prenatal tobacco smoke exposure on biological parameters of the developing brainstemAnna Maria Lavezzi
Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and Sudden Infant Death Syndrome SIDS, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
Neurobiol Dis 20:601-7. 2005....
Biopathology of the dentate-olivary complex in sudden unexplained perinatal death and sudden infant death syndrome related to maternal cigarette smokingAnna Maria Lavezzi
Institute of Pathology, Lino Rossi Research Center, University of Milan, Milan, Italy
Neurol Res 29:525-32. 2007..The present study was aimed to evaluate the possible presence of cytohistologic and/or biologic modifications of the human dentate-olivary complex in sudden unexplained perinatal and infant deaths...
Techniques and criteria in pathologic and forensic-medical diagnostics in sudden unexpected infant and perinatal deathLuigi Matturri
Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Milan, Italy
Am J Clin Pathol 124:259-68. 2005..The data and arguments presented herein provide a brief survey tending to open, rather than conclude, a far-reaching subject and to motivate medicolegal specialists and pathologists to perform more in-depth study...
Cytoarchitectural organization of the parabrachial/Kölliker-Fuse complex in manAnna Maria Lavezzi
Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
Brain Dev 26:316-20. 2004..The neuronal maturation of these nuclei was seen to occur between the 35th and the 36th gestational weeks...
Biology of the smooth muscle cells in human atherosclerosisAnna Maria Lavezzi
Institute of Pathology, University of Milan, Italy
APMIS 113:112-21. 2005..The observation in some cases of chromosome 7 alterations, markers of tumorigenesis, suggests the possible transformation of an advanced atherosclerotic plaque into a neoplastic-like process...
Analysis of the human locus coeruleus in perinatal and infant sudden unexplained deaths. Possible role of the cigarette smoking in the development of this nucleusAnna Maria Lavezzi
Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
Brain Res Dev Brain Res 154:71-80. 2005....
Early atherosclerotic lesions in infancy: role of parental cigarette smokingLuigi Matturri
Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death of term fetus stillbirth and neonatal and Sudden Infant Death Syndrome SIDS, University of Milan, Milan, Italy
Virchows Arch 447:74-80. 2005..We suggest that the oxidants present in the gas phase of the parental cigarette smoke pass through the endothelium and induce at first the c-fos gene activation and subsequently the PCNA positivity, that is, a proliferative process...
Ontogenesis of human cerebellar cortex and biopathological characterization in sudden unexplained fetal and infant deathAnna Maria Lavezzi
Institute of Pathology, Lino Rossi Research Center, University of Milan, Via della Commenda, 19, Milan, 20122, Italy
Virchows Arch 450:31-40. 2007..Maternal smoking is increasingly being demonstrated to be one of the main contributors to developmental neurological alterations in the offspring...
Psychosocial and functional outcomes in long-term survivors of osteosarcoma: a comparison of limb-salvage surgery and amputationRhonda S Robert
Division of Pediatrics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Pediatr Blood Cancer 54:990-9. 2010..We hypothesized there to be neither psychosocial nor functional outcome differences between groups...
Study of the brainstem, particularly the arcuate nucleus, in sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death (SIUD)Luigi Matturri
Institute of Pathology, University of Milan, Italy
Am J Forensic Med Pathol 25:44-8. 2004..The simplified examination of the brainstem makes it possible to evaluate the structures, examining 3 specific levels, defined by morphologic reference points...
Guidelines for neuropathologic diagnostics of perinatal unexpected loss and sudden infant death syndrome (SIDS): a technical protocolLuigi Matturri
Institute of Pathology, University of Milan, Via della Commenda, Milan, Italy
Virchows Arch 452:19-25. 2008....
Alterations of biological features of the cerebellum in sudden perinatal and infant deathAnna Maria Lavezzi
Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Italy
Curr Mol Med 6:429-35. 2006....
Hypoplasia of the parabrachial/kölliker-fuse complex in perinatal deathAnna Maria Lavezzi
Institute of Pathology, University of Milan, Milan, Italy
Biol Neonate 86:92-7. 2004..Such hypoplasia was associated with severe hypoplasia of the arcuate nucleus and pulmonary hypoplasia...
Multifocal cardiac Purkinje cell tumor in infancyGiulia Ottaviani
Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
Europace 6:138-41. 2004..Necroscopy studies of sudden infant death should always include an accurate histological examination of the cardiac conduction system and brainstem using serial sections...
Involvement of the EN-2 gene in normal and abnormal development of the human arcuate nucleusAnna Maria Lavezzi
Institute of Pathology, University of Milan, Italy
Int J Exp Pathol 86:25-31. 2005..In conclusion, we support the role of the EN-2 gene in the normal neuronal development and in the anatomic organization of the human ArcN as well as the possible existence of EN-2 mutations related to hypoplasia of this nucleus...
Hypoplasia of the arcuate nucleus and maternal smoking during pregnancy in sudden unexplained perinatal and infant deathAnna Maria Lavezzi
Institute of Pathology, University of Milan, Italy
Neuropathology 24:284-9. 2004....
Preliminary study on the cytoarchitecture of the human parabrachial/Kölliker-fuse complex, with reference to sudden infant death syndrome and sudden intrauterine unexplained deathAnna Maria Lavezzi
Institute of Pathology, University of Milan, Via della Commenda 19, 20122, Milan, Italy
Pediatr Dev Pathol 7:171-9. 2004....
Unexpected perinatal death and sudden infant death syndrome (SIDS): anatomopathologic and legal aspectsLuigi Matturri
Institute of Pathology, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and Sudden Infant Death Syndrome SIDS, University of Milan, Milan, Italy
Am J Forensic Med Pathol 26:155-60. 2005....
Histological and biological developmental characterization of the human cerebellar cortexAnna Maria Lavezzi
Institute of Pathology, Lino Rossi Research Center, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
Int J Dev Neurosci 24:365-71. 2006..Consequently, we can diagnose delayed or altered processes of differentiation during the development of the human cerebellar cortex...
Maternal smoking and sudden infant death syndrome: epidemiological study related to pathologyLuigi Matturri
Institute of Pathology, University of Milan, Via della Commenda, 19, 20122 Milan, Italy
Virchows Arch 449:697-706. 2006..A significant relation was found between maternal smoke and brainstem alterations...
Sudden unexpected death of a term fetus in an anticardiolipin-positive motherGiulia Ottaviani
Institute of Pathology, University of Milan, Italy
Am J Perinatol 21:79-83. 2004....
Identification of neurons responding to hypoxia in sudden infant death syndromeAnna Maria Lavezzi
Institute of Pathology, University of Milan, Milan, Italy
Pathol Int 53:769-74. 2003..Our results support the respiratory theory of SIDS...
Sudden infant death syndrome "gray zone" disclosed only by a study of the brain stem on serial sectionsGiulia Ottaviani
University of Milan, Milan, Italy
J Perinat Med 33:165-9. 2005....
Early atherosclerotic lesions of the cardiac conduction system arteries in infantsLuigi Matturri
Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy
Cardiovasc Pathol 13:276-81. 2004..In particular, to the best of our knowledge, none has considered the lesions of the cardiac conduction arteries as an initial stage of atherosclerosis...
Association between pulmonary hypoplasia and hypoplasia of arcuate nucleus in stillbirthLuigi Matturri
Institute of Pathology, University of Milan, Italy
J Perinatol 23:328-32. 2003..When the pulmonary hypoplasia is not accompanied by hypodevelopment of this nucleus the explanation could be a failure to block the inhibitory action of the Kölliker-Fuse nucleus...
Sudden infant death syndrome (SIDS) shortly after hexavalent vaccination: another pathology in suspected SIDS?Giulia Ottaviani
Institute of Pathology, University of Milan, Via della Commenda 19, Milan 20122, Italy
Virchows Arch 448:100-4. 2006..Any case of sudden unexpected death occurring perinatally and in infancy, especially soon after a vaccination, should always undergo a full necropsy study according to our guidelines...
Pathogenesis of early atherosclerotic lesions in infantsLuigi Matturri
Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy
Pathol Res Pract 200:403-10. 2004..The lesions appear to be larger and more diffuse when both these atherogenic factors are present...
Involvement of somatostatin in breathing control before and after birth, and in perinatal and infant sudden unexplained deathAnna Maria Lavezzi
Institute of Pathology, University of Milan, Italy
Folia Neuropathol 42:59-65. 2004....
Expression of apoptosis and proliferating cell nuclear antigen (PCNA) in the cardiac conduction system of crib death (SIDS)L Matturri
Istituto di Anatomia Patologica, Universita degli Studi di Milano, Via della Commenda, 19 20122 Milano, Italy
Adv Clin Path 5:79-86. 2001..The AI was higher in the AVN, HB and the initial tract of bundle branches than in the common myocardium (p<0.05; Student's t test)...
Intimal preatherosclerotic thickening of the coronary arteries in human fetuses of smoker mothersL Matturri
Institute of Pathology, State University of Milan, Via della Commenda 19, 20122 Milan, Italy
J Thromb Haemost 1:2234-8. 2003..Many studies have described the development of preatherosclerotic coronary artery lesions in infancy. The observations reported in the literature regarding the fetal origin of coronary artery lesions are rare and controversial...
Role of somatostatin and apoptosis in breathing control in sudden perinatal and infant unexplained deathA M Lavezzi
Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and Sudden Infant Death Syndrome, Institute of Pathology, University of Milan, Italy
Clin Neuropathol 23:304-10. 2004..To obtain basic information about the expression of somatostatin in the human central nervous system and, in particular, to evaluate its possible involvement in unexplained perinatal and in sudden infant death syndrome...
Sudden Infant Death Syndrome (SIDS): a study of cardiac conduction systemL Matturri
Institute of Pathology, University of Milan, Milan, Italy
Cardiovasc Pathol 9:137-45. 2000..These data suggest the need for an accurate approach and examination of the cardiac conduction system in all cases of sudden death in infancy..
Autoptic examination in sudden infant death syndrome and sudden intrauterine unexpected death: proposal of a national lawL Matturri
Institute of Pathology, University of Milan, Milan, Italy
J Matern Fetal Neonatal Med 16:43-5. 2004..The objectives of this law include, in article 4, widespread informative and preventive campaigns and continuous formation of programs for medical personnel...
Clinical and pathologic study of two siblings with osteosarcomaGiulia Ottaviani
Institute of Pathology, University of Milan, Milano, Italy
Med Pediatr Oncol 38:62-4. 2002
Prognostic significance of different biomarkers (DNA content, PCNA, karyotype) in colorectal adenomasAnna Maria Lavezzi
Department of Pathology, University of Milan, Italy
Anticancer Res 22:2077-81. 2002..It was concluded that the combination of some biomarkers (additional chromosomes 11, high PCNA and DNA indices) may allow identification of more aggressive colorectal adenomas with increased ability to undergo malignant transformation...
Sudden infant death triggered by dive reflexL Matturri
Lino Rossi Research Centre for the study and prevention of unexpected perinatal death and sudden infant death syndrome (SIDS, Institute of Pathology, University of Milan, 20122 Italy
J Clin Pathol 58:77-80. 2005..The possible role of parental cigarette smoking in the pathogenesis of arcuate nucleus hypoplasia and early coronary atherosclerotic lesions is also discussed...
Cardiac massage in infantsLuigi Matturri
Intensive Care Med 29:1199-200. 2003
Perinatal and infant early atherosclerotic coronary lesionsJose Milei
Instituto de Investigaciones Cardiologicas, University of Buenos Aires CONICET, Buenos Aires, Argentina
Can J Cardiol 24:137-41. 2008..Because the fetal origin of coronary artery lesions is controversial, early atherosclerotic coronary artery lesions in late fetal stillborns and infants, as well as the possible atherogenic role of maternal cigarette smoking, were studied...
Unexpected sudden death related to medullary brain lesionsLuigi Matturri
Acta Neuropathol 109:554-5. 2005
Treatment of massive tibial bone loss due to chronic draining osteomyelitis: fibula transport using the Ilizarov frameMaurizio A Catagni
Department of Orthopedics and Ilizarov Unit, Alessandro Manzoni Hospital, Via Dell Eremo 9 11, 23900 Lecco, Italy
Orthopedics 30:608-11. 2007..This article affirms the value of the application of the Ilizarov frame for gradual transport of the ipsilateral fibula to replace massive tibial bone loss following chronic refractory osteomyelitis...
Medial fibula transport with the Ilizarov frame to treat massive tibial bone lossMaurizio A Catagni
Department of Orthopedics and Ilizarov Unit, Alessandro Manzoni Hospital, Lecco, Italy
Clin Orthop Relat Res 448:208-16. 2006..LEVEL OF EVIDENCE: Therapeutic Study, Level IV (case series). See the Guidelines for Authors for a complete description of levels of evidence...
