M Onofrj

Summary

Affiliation: University of Chieti
Country: Italy

Publications

  1. ncbi request reprint Acute akinesia or akinetic crisis in Parkinson's disease
    A Thomas
    Department of Neurophysiopathology, Movement Disorder Center, Department of Oncology and Neuroscience, University G D Annunzio, Chieti Pescara, Italy
    Neurol Sci 24:219-20. 2003
  2. pmc Event related potentials recorded in patients with locked-in syndrome
    M Onofrj
    Department of Neurology, University of Chieti, Italy
    J Neurol Neurosurg Psychiatry 63:759-64. 1997
  3. ncbi request reprint Optic neuritis with residual tunnel vision in perchloroethylene toxicity
    M Onofrj
    University G D Annunzio, Chieti, Italy or
    J Toxicol Clin Toxicol 36:603-7. 1998
  4. ncbi request reprint Olanzapine in severe Gilles de la Tourette syndrome: a 52-week double-blind cross-over study vs. low-dose pimozide
    M Onofrj
    Dipartimento di Oncologia e Neuroscienze, Universita G D Annunzio, Ospedale Civile, Italy
    J Neurol 247:443-6. 2000
  5. ncbi request reprint Switch-over from tolcapone to entacapone in severe Parkinson's disease patients
    M Onofrj
    Department of Oncology and Neuroscience, Neurophysiopathology, University G D Annunzio, via Fonte Romano, I 65100 Pescara, Italy
    Eur Neurol 46:11-6. 2001
  6. doi request reprint Neuromagnetic responses reveal the cortical timing of audiovisual synchrony
    R Franciotti
    Department of Neuroscience and Imaging, G D Annunzio University, Chieti, Italy
    Neuroscience 193:182-92. 2011
  7. doi request reprint Persistent genital arousal disorder associated with functional hyperconnectivity of an epileptic focus
    F Anzellotti
    Department of Oncology and Neuroscience, Aging Research Centre, CeSI, G d Annunzio University Foundation, G D Annunzio University, Chieti, Italy
    Neuroscience 167:88-96. 2010
  8. pmc Duration of amantadine benefit on dyskinesia of severe Parkinson's disease
    A Thomas
    Neurophysiopathology, Movement Disorders Centre, Department of Oncology and Neuroscience, Universita G D Annunzio, Chieti Pescara, Pescara, Italy
    J Neurol Neurosurg Psychiatry 75:141-3. 2004
  9. doi request reprint Long half-life and prolonged-release dopamine receptor agonists: a review of ropinirole prolonged-release studies
    M Onofrj
    Department of Oncology and Neurosciences, University G D Annunzio, Chieti Pescara, Italy
    Parkinsonism Relat Disord 15:S85-92. 2009
  10. ncbi request reprint Visual hallucinations in Parkinson's disease: clues to separate origins
    M Onofrj
    Neurophysiopathology, Movement Disorders Center, Department of Oncology and Neuroscience, University G D Annunzio Chieti Pescara, Italy
    J Neurol Sci 248:143-50. 2006

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Acute akinesia or akinetic crisis in Parkinson's disease
    A Thomas
    Department of Neurophysiopathology, Movement Disorder Center, Department of Oncology and Neuroscience, University G D Annunzio, Chieti Pescara, Italy
    Neurol Sci 24:219-20. 2003
    ..In all patients a definite refractoriness to therapy was shown with a transient lack of response to apomorphine...
  2. pmc Event related potentials recorded in patients with locked-in syndrome
    M Onofrj
    Department of Neurology, University of Chieti, Italy
    J Neurol Neurosurg Psychiatry 63:759-64. 1997
    ..To determine the possibility of recording "cognitive" event related potentials (ERPs) in locked-in patients and therefore to determine whether ERPs can have a role in differential diagnosis of coma...
  3. ncbi request reprint Optic neuritis with residual tunnel vision in perchloroethylene toxicity
    M Onofrj
    University G D Annunzio, Chieti, Italy or
    J Toxicol Clin Toxicol 36:603-7. 1998
    ..Visual disturbances consisted of complete blindness for 9 days in the left eye, for 11 days in the right eye, with bright phosphenes and pain on eye rotation. Only central (2-3 degrees radius) vision recovered in the following months...
  4. ncbi request reprint Olanzapine in severe Gilles de la Tourette syndrome: a 52-week double-blind cross-over study vs. low-dose pimozide
    M Onofrj
    Dipartimento di Oncologia e Neuroscienze, Universita G D Annunzio, Ospedale Civile, Italy
    J Neurol 247:443-6. 2000
    ..At the end of the study all patients opted for olanzapine treatment...
  5. ncbi request reprint Switch-over from tolcapone to entacapone in severe Parkinson's disease patients
    M Onofrj
    Department of Oncology and Neuroscience, Neurophysiopathology, University G D Annunzio, via Fonte Romano, I 65100 Pescara, Italy
    Eur Neurol 46:11-6. 2001
    ....
  6. doi request reprint Neuromagnetic responses reveal the cortical timing of audiovisual synchrony
    R Franciotti
    Department of Neuroscience and Imaging, G D Annunzio University, Chieti, Italy
    Neuroscience 193:182-92. 2011
    ..In addition, in the AMB condition the conscious awareness of asynchrony might be associated to a later activation of the primary auditory cortex...
  7. doi request reprint Persistent genital arousal disorder associated with functional hyperconnectivity of an epileptic focus
    F Anzellotti
    Department of Oncology and Neuroscience, Aging Research Centre, CeSI, G d Annunzio University Foundation, G D Annunzio University, Chieti, Italy
    Neuroscience 167:88-96. 2010
    ..Treatment completely abolished PGAD symptoms and functional hyperconnectivity. The functional hyperconnectivity found in the neuronal network including the epileptic focus could suggest a possible central mechanism for PGAD...
  8. pmc Duration of amantadine benefit on dyskinesia of severe Parkinson's disease
    A Thomas
    Neurophysiopathology, Movement Disorders Centre, Department of Oncology and Neuroscience, Universita G D Annunzio, Chieti Pescara, Pescara, Italy
    J Neurol Neurosurg Psychiatry 75:141-3. 2004
    ..A double-blind study programmed over 12 months was designed to assess the duration of the antidyskinetic effect of amantadine on levodopa induced dyskinesia...
  9. doi request reprint Long half-life and prolonged-release dopamine receptor agonists: a review of ropinirole prolonged-release studies
    M Onofrj
    Department of Oncology and Neurosciences, University G D Annunzio, Chieti Pescara, Italy
    Parkinsonism Relat Disord 15:S85-92. 2009
    ..The study with ropinirole as an add-on to L-dopa showed a reduced incidence of dyskinesias...
  10. ncbi request reprint Visual hallucinations in Parkinson's disease: clues to separate origins
    M Onofrj
    Neurophysiopathology, Movement Disorders Center, Department of Oncology and Neuroscience, University G D Annunzio Chieti Pescara, Italy
    J Neurol Sci 248:143-50. 2006
    ..Our studies support a recently proposed integrative model of VH, and show that the neural circuits purported to explain VH must include the retinal dopaminergic system and the REM sleep regulatory system...
  11. ncbi request reprint Improvement of motor function in early Parkinson disease by safinamide
    F Stocchi
    Department of Neuroscience and IRCCS Neuromed Pozzilli IS, Disorders Centre, Department of Neuroscience, Universita G D Annunzio, Chieti Pescara, Pescara, Italy
    Neurology 63:746-8. 2004
    ..7-point motor score decrease; p > or = 0.05). These results suggest that doses of SAF exerting ion channel block and glutamate release inhibition add to its symptomatic effect and warrant exploration of higher doses...
  12. ncbi request reprint Donepezil, rivastigmine, and vitamin E in Alzheimer disease: a combined P300 event-related potentials/neuropsychologic evaluation over 6 months
    A Thomas
    Department of Oncology and Neuroscience, Institute of Neurophysiopathology, University G. D'Annunzio, Pescara, Italy
    Clin Neuropharmacol 24:31-42. 2001
    ..Combined P300 and neuropsychologic test evaluation significantly separated DPZ-treated patients and Riv-treated patients from vitamin E-treated patients...
  13. doi request reprint Visual hallucinations in PD and Lewy body dementias: old and new hypotheses
    M Onofrj
    Department of Neuroscience and Imaging, University G d Annunzio of Chieti Pescara, Chieti, Italy Aging Research Center, G d Annunzio University Foundation, Chieti, Italy
    Behav Neurol 27:479-93. 2013
    ..We review the different methods used to classify VH and discuss reports supporting or challenging the different hypothetical mechanisms of VH. ..
  14. ncbi request reprint Low- and high-frequency evoked responses following pattern reversal stimuli: a MEG study supported by fMRI constraint
    B Perfetti
    Department of Clinical Sciences and Bioimaging, University of Chieti, and ITAB, Fondazione Universita G D Annunzio, Chieti, Italy
    Neuroimage 35:1152-67. 2007
    ....
  15. pmc Clinically evidenced unilateral dissociation of saccades and pursuit eye movements
    M Onofrj
    Neurophysiopathology, University Chieti Pescara, Pescara, Italy
    J Neurol Neurosurg Psychiatry 75:1048-50. 2004
    ..Clinical observations were confirmed by magnetic field scleral search coils analysis. During the vertical eye movement the patient denied any diplopia, thus suggesting a transient visual suppression in the left eye...
  16. ncbi request reprint Age-related changes of evoked potentials
    M Onofrj
    Department of Oncology and Neuroscience, University G D Annunzio, Chieti, Italy
    Neurophysiol Clin 31:83-103. 2001
    ..Different techniques as event-related desynchronization (ERD), contingent negative variation (CNV) and Bereitschaftspotential, are available to study central neuronal changes in normal and pathologic ageing...
  17. doi request reprint Combined rehabilitation program for postural instability in progressive supranuclear palsy
    L Di Pancrazio
    Department of Human Movement, G D Annunzio University, Chieti, Italy
    NeuroRehabilitation 32:855-60. 2013
    ..The clinical response to L-dopa is poor and there is strong need for alternative treatment strategies...
  18. ncbi request reprint Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism
    M Onofrj
    Department of Oncology and Neuroscience, University G D Annunzio, Pescara, Italy
    Neurology 60:113-5. 2003
    ..These disturbances resolved with drug discontinuation, and remained resolved by 12- to 24-month follow-up, suggesting that RBD can be triggered by a drug lacking anticholinergic activity...
  19. doi request reprint Peripheral cytokines profile in Parkinson's disease
    M Reale
    Department of Oncology and Neuroscience, University G D Annunzio Chieti Pescara, Italy
    Brain Behav Immun 23:55-63. 2009
    ..The overall results strengthen and extend the knowledge of the peripheral dysregulation in the cytokine network associated with PD...
  20. ncbi request reprint Delayed and pseudodelayed visual evoked potentials in optic neuritis compared with long time echo-short tau inversion recovery magnetic resonance imaging of optic nerve
    M Onofrj
    Department of Neurology, State University of Chieti, Chieti, Italy
    Electroencephalogr Clin Neurophysiol 100:275-86. 1996
    ..There was no correlation between latency of VEPs and length of plaques. Our study addresses some reconsiderations of the pathophysiology of conduction delay in acute optic neuritis...
  21. ncbi request reprint Reversible parkinsonism induced by prolonged treatment with valproate
    M Onofrj
    Dipartimento di Oncologia e Neuroscienze, Clinica Neurologica, Chieti, Italy
    J Neurol 245:794-6. 1998
    ..Parkinsonism disappeared in less than 3 months after VPA substitution with carbamazepine...
  22. doi request reprint Ascertainment bias in dementias: a secondary to tertiary centre analysis in Central Italy and conceptual review
    L Bonanni
    Institute of Neurology G d Annunzio University Chieti Pescara and Aging Research Center, Ce S I University Foundation Chieti, Chieti, Italy
    Aging Clin Exp Res 25:265-74. 2013
    ....
  23. ncbi request reprint Symptomatic REM sleep behaviour disorder
    A Thomas
    Neurophysiopathology, Movement Disorders Center, University G D Annunzio Chieti and Pescara, Italy, Via Fonte Romane, I 65124, Pescara, Italy
    Neurol Sci 28:S21-36. 2007
    ..Controversial findings, flaws in categorisation and hypothetical aetiological mechanisms are also discussed...
  24. ncbi request reprint Psychophysical distress and alexithymic traits in chronic fatigue syndrome with and without comorbid depression
    G Sepede
    Department of Neuroscience and Imaging, University of Chieti, Italy
    Int J Immunopathol Pharmacol 24:1017-25. 2011
    ..These findings suggest an urgent need to address and treat depressive disorders in the clinical care of CFS cases, to improve social functioning and quality of life in such patients...
  25. pmc Severe outcome of pharyngeal-cervical-brachial pure motor axonal neuropathy
    L Bonanni
    Department of Neurology, University G D Annunzio of Chieti Pescara and Aging Research Center, Ce S I, Gabriele D Annunzio University Foundation, Italy
    Open Neurol J 4:1-4. 2010
    ..Normal reflexes, F waves and action potentials were elicited in lower limbs. Despite i.v. Immunoglobulin treatment no recovery was observed and both patients died within a year from onset of symptoms...
  26. ncbi request reprint Cortical rhythms reactivity in AD, LBD and normal subjects: a quantitative MEG study
    R Franciotti
    Department of Clinical Sciences and Bioimaging, University of Chieti, Italy ITAB, G d Annunzio University Foundation, Chieti, Italy
    Neurobiol Aging 27:1100-9. 2006
    ..These results suggest that investigations on rhythms reactivity and spectral coherence might help on the study of the dementias with different etiology...
  27. ncbi request reprint Optimizing levodopa pharmacokinetics in Parkinson's disease: the role of COMT inhibitor
    F Stocchi
    IRRCS Neuromed, Pozzilli Is, Italy
    Neurol Sci 24:217-8. 2003
  28. ncbi request reprint Amantadine for dyskinesia in patients affected by severe Parkinson's disease
    C Paci
    Neurophysiopathology Service, G. D'Annunzio University, Pescara, Italy
    Neurol Sci 22:75-6. 2001
    ..5). In the two patients with hyperthemia amantadine was reintroduced; after four days hyperthermia subsided and amantadine was finally tapered over 15 days without further adverse reactions...
  29. ncbi request reprint Combining entacapone with levodopa/DDCI improves clinical status and quality of life in Parkinson's Disease (PD) patients experiencing wearing-off, regardless of the dosing frequency: results of a large multicentre open-label study
    M Onofrj
    Servizio di Neurofisiopatologia, Pescara, Italy
    J Neural Transm 111:1053-63. 2004
    ....
  30. ncbi request reprint Incidence of RBD and hallucination in patients affected by Parkinson's disease: 8-year follow-up
    M Onofrj
    Department of Oncology and Neuroscience Neurophysiopathology, G D Annunzio University, Ospedale Civile di Pescara, via Fonte Romana, I 65124 Pescara, Italy
    Neurol Sci 23:S91-4. 2002
    ..However, the presence of REM sleep behavioral disorder (RBD) was significantly related to the development of hallucinations,independently of age, gender or duration of disease but dependent on the amount of dopaminoagonist treatment...
  31. ncbi request reprint Health-related quality of life in epilepsy: findings obtained with a new Italian instrument
    Ada Piazzini
    Epilepsy Center, St Paolo Hospital, Milan, Italy
    Epilepsy Behav 13:119-26. 2008
    ..We believe that a new specific questionnaire for the evaluation of HRQOL in Italy can contribute much to the understanding of the influence of epilepsy on patients' lives...