Oliviero Olivieri

Summary

Affiliation: University of Verona
Country: Italy

Publications

  1. ncbi request reprint Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine, University of Verona, P le L A Scuro10, Verona, Italy
    Mol Biosyst 10:1281-9. 2014
  2. pmc Access rate to the emergency department for venous thromboembolism in relationship with coarse and fine particulate matter air pollution
    Nicola Martinelli
    Section of Internal Medicine, Department of Medicine, University of Verona, Verona, Italy
    PLoS ONE 7:e34831. 2012
  3. doi request reprint Urinary prostasin in normotensive individuals: correlation with the aldosterone to renin ratio and urinary sodium
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine B, University of Verona, Verona, Italy
    Hypertens Res 36:528-33. 2013
  4. ncbi request reprint Aldosterone to Renin ratio in a primary care setting: the Bussolengo study
    Oliviero Olivieri
    Dipartimento Medicina Clinica e Sperimentale, Cattedra di Medicina Interna, Universita di Verona, Policlinico Borgo Roma, 37134 Verona, Italy
    J Clin Endocrinol Metab 89:4221-6. 2004
  5. ncbi request reprint Cystatin C versus creatinine in renovascular disease
    Oliviero Olivieri
    Department of Clinical and Experimental Medicine, Unit of Internal Medicine, University of Verona, 37134 Verona, Italy
    Clin Chem 48:2256-9. 2002
  6. ncbi request reprint ApoC-III gene polymorphisms and risk of coronary artery disease
    Oliviero Olivieri
    Unit of Internal Medicine, Institute of Clinical Chemistry, University of Verona, Verona, Italy
    J Lipid Res 43:1450-7. 2002
  7. doi request reprint Apolipoprotein C-III predicts cardiovascular mortality in severe coronary artery disease and is associated with an enhanced plasma thrombin generation
    O Olivieri
    Department of Clinical and Experimental Medicine, Unit of Internal Medicine, University of Verona, Verona, Italy
    J Thromb Haemost 8:463-71. 2010
  8. doi request reprint Urinary cortisol to cortisone metabolites ratio in prednisone-treated and spontaneously hypertensive patients
    Oliviero Olivieri
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Italy
    J Hypertens 26:486-93. 2008
  9. ncbi request reprint Homocysteine and atheromatous renal artery stenosis
    O Olivieri
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    Clin Exp Med 1:211-8. 2001
  10. doi request reprint ApoE epsilon2/epsilon3/epsilon4 polymorphism, ApoC-III/ApoE ratio and metabolic syndrome
    O Olivieri
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, Cattedra di Medicina Interna, University of Verona, Policlinico Borgo Roma, 37134, Verona, Italy
    Clin Exp Med 7:164-72. 2007

Detail Information

Publications79

  1. ncbi request reprint Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine, University of Verona, P le L A Scuro10, Verona, Italy
    Mol Biosyst 10:1281-9. 2014
    ..In conclusion urine SB3 concentrations are physiologically much lower in males than in females. Hypertensive women, affected by APA, present urinary SB3 concentrations significantly higher than women affected by BAH. ..
  2. pmc Access rate to the emergency department for venous thromboembolism in relationship with coarse and fine particulate matter air pollution
    Nicola Martinelli
    Section of Internal Medicine, Department of Medicine, University of Verona, Verona, Italy
    PLoS ONE 7:e34831. 2012
    ..247; P = 0.012). Our results suggest that short-time exposure to high concentrations of PM(10-2.5) may favour an increased rate of ED accesses for VTE through the induction of a prothrombotic state...
  3. doi request reprint Urinary prostasin in normotensive individuals: correlation with the aldosterone to renin ratio and urinary sodium
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine B, University of Verona, Verona, Italy
    Hypertens Res 36:528-33. 2013
    ..In conclusion, urinary prostasin correlates with the ARR, and it is physiologically modulated by natriuresis in normotensive individuals...
  4. ncbi request reprint Aldosterone to Renin ratio in a primary care setting: the Bussolengo study
    Oliviero Olivieri
    Dipartimento Medicina Clinica e Sperimentale, Cattedra di Medicina Interna, Universita di Verona, Policlinico Borgo Roma, 37134 Verona, Italy
    J Clin Endocrinol Metab 89:4221-6. 2004
    ..As an elevated AARR is frequent in the general hypertensive population, screening should not be limited to the patients referred to specialist units...
  5. ncbi request reprint Cystatin C versus creatinine in renovascular disease
    Oliviero Olivieri
    Department of Clinical and Experimental Medicine, Unit of Internal Medicine, University of Verona, 37134 Verona, Italy
    Clin Chem 48:2256-9. 2002
  6. ncbi request reprint ApoC-III gene polymorphisms and risk of coronary artery disease
    Oliviero Olivieri
    Unit of Internal Medicine, Institute of Clinical Chemistry, University of Verona, Verona, Italy
    J Lipid Res 43:1450-7. 2002
    ..5 and 2.18 for unadjusted and adjusted models, respectively) suggesting that it represents an independent genetic susceptibility factor for CAD...
  7. doi request reprint Apolipoprotein C-III predicts cardiovascular mortality in severe coronary artery disease and is associated with an enhanced plasma thrombin generation
    O Olivieri
    Department of Clinical and Experimental Medicine, Unit of Internal Medicine, University of Verona, Verona, Italy
    J Thromb Haemost 8:463-71. 2010
    ..Apolipopoprotein C-III (apo C-III) plays a pivotal role in controlling plasma triglyceride (TG) and contributes to the atherogenic properties of TG-rich lipoproteins...
  8. doi request reprint Urinary cortisol to cortisone metabolites ratio in prednisone-treated and spontaneously hypertensive patients
    Oliviero Olivieri
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Italy
    J Hypertens 26:486-93. 2008
    ....
  9. ncbi request reprint Homocysteine and atheromatous renal artery stenosis
    O Olivieri
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    Clin Exp Med 1:211-8. 2001
    ..Folate supplementation might be useful in the management of overall vascular risk of these patients...
  10. doi request reprint ApoE epsilon2/epsilon3/epsilon4 polymorphism, ApoC-III/ApoE ratio and metabolic syndrome
    O Olivieri
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, Cattedra di Medicina Interna, University of Verona, Policlinico Borgo Roma, 37134, Verona, Italy
    Clin Exp Med 7:164-72. 2007
    ..Carriers of the unfavourable E4 allele present the highest ApoCIII/ApoE ratio and are twofold more frequent among individuals affected by MetSyn...
  11. ncbi request reprint Different impact of deletion polymorphism of gene on the risk of renal and coronary artery disease
    Oliviero Olivieri
    Department of Clinical and Experimental Medicine, Chair of Internal Medicine, University of Verona, Policlinico Borgo Roma, 37134 Verona, Italy
    J Hypertens 20:37-43. 2002
    ....
  12. ncbi request reprint Apolipoprotein C-III, n-3 polyunsaturated fatty acids, and "insulin-resistant" T-455C APOC3 gene polymorphism in heart disease patients: example of gene-diet interaction
    Oliviero Olivieri
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Clin Chem 51:360-7. 2005
    ..The T-455C polymorphism in the insulin-responsive element of the APOC3 gene influences TG and apo C-III concentrations. Long-chain n-3 polyunsaturated fatty acids (PUFAs) contained in fish have well-known apo C-III-lowering properties...
  13. doi request reprint Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients
    Oliviero Olivieri
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Am J Hypertens 21:976-82. 2008
    ..We therefore designed an interventional study to ascertain whether primary care hypertensive patients with an elevated ARR presented a superior response to MRA treatment than subjects with normal ratio...
  14. ncbi request reprint Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans
    Oliviero Olivieri
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    Hypertension 46:683-8. 2005
    ....
  15. ncbi request reprint Apolipoprotein C-III, metabolic syndrome, and risk of coronary artery disease
    Oliviero Olivieri
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    J Lipid Res 44:2374-81. 2003
    ..6% vs. 34.8%, P < 0.05). In conclusion, apoC-III-rich lipoprotein metabolism and the APOC3 polymorphism have relevant impacts on the CAD risk of MS patents...
  16. ncbi request reprint The -1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study
    Nicola Martinelli
    University of Verona, Department of Clinical and Experimental Medicine, Italy
    Atherosclerosis 191:409-17. 2007
    ..Different genotypes, i.e., APOA5 and APOC3 variants, may lead to similar biochemical phenotypes, namely hypertriglyceridemia, but to contrasting clinical phenotypes such as the presence of angiographically proven CAD...
  17. pmc Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis
    Nicola Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    PLoS ONE 3:e1523. 2008
    ..The aim of this study was to evaluate the combined effect of ten common prothrombotic polymorphisms as a determinant of MI...
  18. pmc Hyperhomocysteinemia and mortality after coronary artery bypass grafting
    Domenico Girelli
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    PLoS ONE 1:e83. 2006
    ..No previous study specifically has addressed the relationship between HHcy and mortality after coronary artery bypass grafting (CABG) surgery. The aim of this study is to evaluate the prognostic impact of HHcy after CABG surgery...
  19. ncbi request reprint FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease
    Nicola Martinelli
    Department of Clinical and Experimental Medicine and the Section of Biology and Genetics, University of Verona, Verona, Italy
    Am J Clin Nutr 88:941-9. 2008
    ..Single-nucleotide polymorphisms (SNPs) in FADS1 and FADS2 have been associated with different concentrations of AA and LA, and those associations have possible functional consequences for desaturase activity...
  20. pmc Factor II activity is similarly increased in patients with elevated apolipoprotein CIII and in carriers of the factor II 20210A allele
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine, University of Verona, Verona, Italy
    J Am Heart Assoc 2:e000440. 2013
    ..Few studies have so far investigated the relationship between apolipoprotein CIII (Apo CIII) and coagulation pathway in subjects with or without coronary artery disease (CAD)...
  21. ncbi request reprint Primary hyperaldosteronism: a frequent cause of residual hypertension after successful endovascular treatment of renal artery disease
    Francesca Pizzolo
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Italy
    J Hypertens 23:2041-7. 2005
    ..We hypothesized that residual hypertension observed in some renal artery disease patients after technically successful endovascular treatment may be due to primary hyperaldosteronism...
  22. ncbi request reprint ALOX5AP gene variants and risk of coronary artery disease: an angiography-based study
    Domenico Girelli
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Eur J Hum Genet 15:959-66. 2007
    ..Our angiography-based study suggests a possible modest role of ALOX5AP in the development of the atheroma rather than in its late thrombotic complications such as MI...
  23. doi request reprint Effects of female sex hormones and contraceptive pill on the diagnostic work-up for primary aldosteronism
    Francesca Pizzolo
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Universita di Verona, Verona, Italy
    J Hypertens 28:135-42. 2010
    ....
  24. doi request reprint Promoter methylation in coagulation F7 gene influences plasma FVII concentrations and relates to coronary artery disease
    Simonetta Friso
    Department of Medicine, University of Verona School of Medicine, Verona, Italy
    J Med Genet 49:192-9. 2012
    ..Transcriptional regulation of F7 by epigenetic features is, however, still unknown as is the inter-relationship of genetic and epigenetic modifications at the promoter site...
  25. pmc Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease
    Ugo Cavallari
    Department of Mother and Child and of Biology Genetics, Section of Biology and Genetics, University of Verona, Verona, Italy
    BMC Med Genet 8:59. 2007
    ..No data are available on its association with coronary artery disease (CAD)...
  26. ncbi request reprint The interaction between MTHFR 677 C-->T genotype and folate status is a determinant of coronary atherosclerosis risk
    Domenico Girelli
    Department of Clinical and Experimental Medicine, Institute of Biology and Genetics, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
    J Nutr 133:1281-5. 2003
    ..8, 95% CI, 1.03-3.15). A gene-nutrient interaction that defines a higher risk for CAD is determined by folate levels below specific thresholds, which differ depending on the MTHFR 677 C-->T genotype...
  27. pmc Serum levels of the hepcidin-20 isoform in a large general population: the Val Borbera study
    Natascia Campostrini
    Department of Medicine, Section of Internal Medicine, University of Verona, Italy
    J Proteomics 76:28-35. 2012
    ..This article is part of a Special Issue entitled: Integrated omics...
  28. pmc Global DNA hypomethylation in peripheral blood mononuclear cells as a biomarker of cancer risk
    Simonetta Friso
    Corresponding Author Simonetta Friso, Department of Medicine, University of Verona School of Medicine, Policlinico G B Rossi, P le L A Scuro, 10, 37134 Verona, Italy
    Cancer Epidemiol Biomarkers Prev 22:348-55. 2013
    ..Whether methylation measured in peripheral blood mononuclear cells (PBMCs) DNA is a clinically reliable biomarker for early detection or cancer risk assessment is to be established...
  29. pmc Additive effect of LRP8/APOER2 R952Q variant to APOE epsilon2/epsilon3/epsilon4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study
    Nicola Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    BMC Med Genet 10:41. 2009
    ....
  30. doi request reprint Hepcidin is not useful as a biomarker for iron needs in haemodialysis patients on maintenance erythropoiesis-stimulating agents
    Nicola Tessitore
    Hemodialysis Unit Ospedale Policlinico, Division of Nephrology, University of Verona, Verona, Italy
    Nephrol Dial Transplant 25:3996-4002. 2010
    ..It has been suggested that hepcidin may be useful as a tool for managing iron therapy in haemodialysis (HD) patients on erythropoiesis-stimulating agents (ESA)...
  31. doi request reprint Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile
    Nicola Martinelli
    Department of Medicine, University of Verona, Verona, Italy
    Blood 116:5688-97. 2010
    ..67 with 95% confidence interval, 1.10-2.54). Haplotype analysis confirmed such results. Our data suggest that polymorphisms at LDLR locus modulate FVIII:c levels and may be associated with CAD risk independently from plasma lipids...
  32. doi request reprint Epigenetic control of 11 beta-hydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension
    Simonetta Friso
    Department of Clinical and Experimental Medicine, University of Verona School of Medicine, Verona, Italy
    Atherosclerosis 199:323-7. 2008
    ..Little is known, however, of human HSD11B2 epigenetic control and its relationship with the onset of hypertension...
  33. ncbi request reprint The MTHFR 1298A>C polymorphism and genomic DNA methylation in human lymphocytes
    Simonetta Friso
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico Giambattista Rossi, Piazza Ludovico Antonio Scuro, 10, 37134 Verona, Italy
    Cancer Epidemiol Biomarkers Prev 14:938-43. 2005
    ..Further mechanistic studies are warranted to investigate how single polymorphisms as well as MTHFR combined genotypes exert their effect on cancer susceptibility...
  34. ncbi request reprint Renovascular disease: effect of ACE gene deletion polymorphism and endovascular revascularization
    Francesca Pizzolo
    Section of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Policlinico Borgo Roma, 37134 Verona, Italy
    J Vasc Surg 39:140-7. 2004
    ....
  35. ncbi request reprint Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk
    Simonetta Friso
    Department of Clinical and Experimental Medicine, University of Verona School of Medicine, Verona, Italy
    Am J Clin Nutr 79:992-8. 2004
    ..Both low PLP and elevated inflammatory markers, such as high-sensitivity CRP (hs-CRP) and fibrinogen, are related to higher risk of coronary artery disease (CAD)...
  36. ncbi request reprint Prevalence of body iron excess in the metabolic syndrome
    Claudia Bozzini
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
    Diabetes Care 28:2061-3. 2005
  37. doi request reprint Detection of a large deletion in the P-selectin (SELP) gene
    Alessandra Pasquali
    Department of Mother and Child, and Biology Genetics, University of Verona, Strada Le Grazie 8, Verona, Italy
    Mol Cell Probes 24:161-5. 2010
    ..Re-genotyping of 1023 apparent homozygotes indicated an overall allele frequency of 0.27%. The inclusion of this allelic variant in genetic association studies will avoid genotyping errors and marginally improve the sensitivity...
  38. ncbi request reprint On the association of the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction or coronary artery disease
    Elisabetta Trabetti
    Department of Mother and Child and of Biology Genetics, Section of Biology and Genetics, University of Verona, Verona, Italy
    Eur J Hum Genet 14:127-30. 2006
    ..Even if the OLR1 genotype frequency distribution data in CAD or AMI subjects here reported do not fully confirm the positive results of some other association studies, an association with a marker of CAD severity was observed...
  39. ncbi request reprint Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis
    Claudia Bozzini
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
    Thromb Haemost 92:541-9. 2004
    ..This study highlights a "within-gene" interaction, and the need to explore polymorphisms in candidate gene(s) in detail...
  40. pmc Low levels of serum paraoxonase activities are characteristic of metabolic syndrome and may influence the metabolic-syndrome-related risk of coronary artery disease
    Nicola Martinelli
    Department of Medicine, University of Verona, Policlinico G B Rossi, Italy
    Exp Diabetes Res 2012:231502. 2012
    ..45 with 95% CI 0.47-4.46). Our results suggest that low PON1 concentrations are typical in MS and may modulate the MS-related risk of CAD...
  41. ncbi request reprint Increased factor VIII coagulant activity levels in male carriers of the factor V R2 polymorphism
    Nicola Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    Blood Coagul Fibrinolysis 18:125-9. 2007
    ..The report concomitantly addresses the relationship between factor V and factor VIII levels and supports the hypothesis of a mild prothrombotic role of FVHR2 by means of increased factor VIII levels...
  42. ncbi request reprint Folic acid effects on s-adenosylmethionine, s-adenosylhomocysteine, and DNA methylation in patients with intermediate hyperhomocysteinemia
    Francesca Pizzolo
    Department of Medicine, University of Verona School of Medicine, Verona, Italy
    J Am Coll Nutr 30:11-8. 2011
    ..The purpose of this study was to investigate the effects of FA supplementation on AdoMet, AdoHcy, and genomic DNA methylation in hyperhomocysteinemic subjects without end-stage renal disease...
  43. doi request reprint Novel serum paraoxonase activity assays are associated with coronary artery disease
    Nicola Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Clin Chem Lab Med 47:432-40. 2009
    ..The aim of this study was to evaluate for the first time TBBLase and DEPCyMCase activity in patients with coronary artery disease (CAD)...
  44. doi request reprint Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis
    Claudia Bozzini
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
    Blood Cells Mol Dis 40:347-52. 2008
    ..This study measured urinary hepcidin levels by SELDI-TOF-MS in a large group of HH patients at diagnosis and during treatment, including both C282Y homozygous and C282Y/H63D compound heterozygotes...
  45. doi request reprint SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease
    Giovanni Malerba
    Department of Mother and Child, and Biology Genetics, Section of Biology and Genetics, University of Verona, Verona, Italy
    Lipids 43:289-99. 2008
    ....
  46. ncbi request reprint Biochemical and genetic markers of iron status and the risk of coronary artery disease: an angiography-based study
    Claudia Bozzini
    Department of Clinical and Experimental Medicine, University of Verona, 37134 Verona, Italy
    Clin Chem 48:622-8. 2002
    ..Iron may promote coronary atherosclerotic disease (CAD) by increasing lipid peroxidation. Studies on biochemical or genetic markers of body iron stores as risk factors for CAD have yielded conflicting results...
  47. doi request reprint Female urinary proteomics: New insight into exogenous and physiological hormone-dependent changes
    Annalisa Castagna
    Department of Medicine, Unit of Internal Medicine, University of Verona, Italy
    Proteomics Clin Appl 5:343-53. 2011
    ..Clinical parameters and renin-angiotensin-aldosterone system (RAAS) components were also investigated, on the basis of the well-known relation linking sex female hormones and renin and aldosterone levels...
  48. doi request reprint Murine macrophages response to iron
    Rita Polati
    University of Verona, Department of Biotechnology, Strada Le Grazie 15, 37134 Verona, Italy
    J Proteomics 76:10-27. 2012
    ..This article is part of a Special Issue entitled: Integrated omics...
  49. ncbi request reprint Paraoxonases: ancient substrate hunters and their evolving role in ischemic heart disease
    Nicola Martinelli
    Department of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy
    Adv Clin Chem 59:65-100. 2013
    ..In this review, we examine the biochemical pathways impacted by these unique enzymes and investigate the potential use of PON as diagnostic tools and their impact on development of future therapeutic strategies...
  50. pmc Evaluation of hepcidin isoforms in hemodialysis patients by a proteomic approach based on SELDI-TOF MS
    Natascia Campostrini
    Department of Medicine, University of Verona, 37134 Verona, Italy
    J Biomed Biotechnol 2010:329646. 2010
    ..Measurement of hepcidin isoforms through MS-based techniques can be a useful tool for better understanding of their biological role in hemodialysis patients and other clinical conditions...
  51. doi request reprint NT-proBNP, a useful tool in hypertensive patients undergoing a diagnostic evaluation for primary aldosteronism
    Francesca Pizzolo
    Division of Internal Medicine, Department of Medicine, University of Verona, pzz le Scuro, 37134, Verona, Italy
    Endocrine 45:479-86. 2014
    ..NT-proBNP and gender are predictors of a positive PA confirmatory test. These findings highlight the possibility of using NT-proBNP to identify which patients with a high ARR should receive a complete PA diagnostic evaluation...
  52. ncbi request reprint Laboratory diagnosis of primary aldosteronism, and drospirenone-ethinylestradiol therapy
    Francesca Pizzolo
    Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Policlinico Borgo Roma, Verona, Italy
    Am J Hypertens 20:1334-7. 2007
    ..Our objective was to evaluate the possible interference of a new progestin with antimineralocorticoid activity (drospirenone) on the determination of ARR and the diagnosis of primary aldosteronism...
  53. ncbi request reprint G20210A prothrombin gene polymorphism and prothrombin activity in subjects with or without angiographically documented coronary artery disease
    C Russo
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Circulation 103:2436-40. 2001
    ..The role of this common polymorphism, as well as that of prothrombin levels, in determining the risk of arterial disease is still somewhat controversial...
  54. doi request reprint A 'desaturase hypothesis' for atherosclerosis: Janus-faced enzymes in omega-6 and omega-3 polyunsaturated fatty acid metabolism
    Nicola Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, Piazzale L A Scuro 10, Verona, Italy
    J Nutrigenet Nutrigenomics 2:129-39. 2009
    ..For these reasons, carriers of specific FADS haplotypes may be predisposed to more pronounced vascular inflammatory damage, but also to an increased beneficial effect with omega-3 PUFA supplementation...
  55. doi request reprint Thrombosis and sickle cell disease
    Lucia De Franceschi
    Department of Medicine, University of Verona, Verona, Italy
    Semin Thromb Hemost 37:226-36. 2011
    ..We also review the available studies on the therapeutic approaches in clinical management of hypercoagulability in SCD...
  56. ncbi request reprint Clinical and pathologic findings in hemochromatosis type 3 due to a novel mutation in transferrin receptor 2 gene
    Domenico Girelli
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Gastroenterology 122:1295-302. 2002
    ..Here we report data from a family carrying a new mutation of the transferrin receptor 2 gene...
  57. doi request reprint Genetic architecture of coronary artery disease in the genome-wide era: implications for the emerging "golden dozen" loci
    Domenico Girelli
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, University of Verona, Italy
    Semin Thromb Hemost 35:671-82. 2009
    ..Although these genetic variants have little or no current predictive value of at the level of individual patients, they have the potential to disclose novel biological mechanisms involved in the pathophysiology of CAD/MI...
  58. ncbi request reprint Erythrocyte aging in neurodegenerative disorders
    L de Franceschi
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, University of Verona, Policlinico GB Rossi, P le L Scuro 10, 37134 Verona, Italy
    Cell Mol Biol (Noisy-le-grand) 50:179-85. 2004
    ..We have reviewed the mechanism(s) of the loss of red cell membrane stability and of the precocious red cell aging in neurodegenerative disorders...
  59. ncbi request reprint Homozygosity for angiotensinogen 235T variant increases the risk of myocardial infarction in patients with multi-vessel coronary artery disease
    O Olivieri
    Department of Clinical and Experimental Medicine, Chair of Internal Medicine, University of Verona, Italy
    J Hypertens 19:879-84. 2001
    ..The primary object of the paper is to verify this possible association by a rigorous, angiographically controlled study in a large sample of patients with or without multi-vessel CAD...
  60. ncbi request reprint Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease
    D Girelli
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    N Engl J Med 343:774-80. 2000
    ..Since polymorphisms in the factor VII gene contribute to variations in factor VII levels, such polymorphisms may be associated with the risk of myocardial infarction, which is precipitated by thrombosis...
  61. ncbi request reprint Genetic polymorphisms of the renin-angiotensin system and atheromatous renal artery stenosis
    O Olivieri
    Department of Clinical and Experimental Medicine, Chair of Internal Medicine, University of Verona, Verona, Italy
    Hypertension 34:1097-100. 1999
    ..34, 95% CI 0.19 to 1.47). No significant association was found for AGT M235T and ATR A1166C. Our results suggest a predisposing role for ACE genetic polymorphism in the development and progression of atheromatous RAS...
  62. doi request reprint Air particulate matter and cardiovascular disease: a narrative review
    Nicola Martinelli
    Department of Medicine, Section of Internal Medicine B, University of Verona, Italy
    Eur J Intern Med 24:295-302. 2013
    ....
  63. ncbi request reprint Infective endocarditis with lung and systemic embolization in an injection drug user
    Nicola Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
    Eur Heart J 27:2938. 2006
  64. ncbi request reprint A1298C methylenetetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism
    S Friso
    Department of Clinical and Experimental Medicine, University of Verona, Italy
    Clin Exp Med 2:7-12. 2002
    ....
  65. pmc Increased serum hepcidin levels in subjects with the metabolic syndrome: a population study
    Nicola Martinelli
    Department of Medicine, University of Verona, Verona, Italy
    PLoS ONE 7:e48250. 2012
    ..Due to recently discovered pleiotropic effects of hepcidin, this may worsen insulin resistance and contribute to the cardiovascular complications of MetS...
  66. pmc Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy
    Angela Siciliano
    Dept of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy
    Haematologica 96:24-32. 2011
    ..Hepatic dysfunction and liver damage may be present in sickle cell disease, but the pathogenesis of these conditions is only partially understood...
  67. doi request reprint Deoxygenation affects tyrosine phosphoproteome of red cell membrane from patients with sickle cell disease
    Angela Siciliano
    Dept of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Blood Cells Mol Dis 44:233-42. 2010
    ....
  68. ncbi request reprint Interaction between smoking and PON2 Ser311Cys polymorphism as a determinant of the risk of myocardial infarction
    N Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Eur J Clin Invest 34:14-20. 2004
    ..We evaluated three PON polymorphisms (PON1 Leu55Met and Gln192Arg; PON2 Ser311Cys) as possible risk factors for coronary atherosclerotic disease (CAD) and/or its main thrombotic complication, myocardial infarction (MI)...
  69. ncbi request reprint Homocysteine, traditional risk factors and impaired renal function in coronary artery disease
    F Pizzolo
    Department of Clinical and Experimental Medicine, University of Verona School of Medicine, Verona, Italy
    Eur J Clin Invest 36:698-704. 2006
    ....
  70. ncbi request reprint Interaction between metabolic syndrome and PON1 polymorphisms as a determinant of the risk of coronary artery disease
    N Martinelli
    Department of Clinical and Experimental Medicine, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
    Clin Exp Med 5:20-30. 2005
    ..No increased risk was found for subjects with MS and the 55Met/Met-192Gln/Gln genotype. This study highlights a potential example of genetic (paraoxonase polymorphisms)-clinical (MS) interaction influencing cardiovascular risk...
  71. ncbi request reprint Recovery of renal function after 3 months of dialysis in a patient with atherosclerotic renovascular disease following aortoiliac bypass and left renal artery reimplantation
    S Simeoni
    Department of Clinical and Experimental Medicine, Chair of Internal Medicine, University of Verona, Verona, Italy
    Eur J Vasc Endovasc Surg 28:562-4. 2004
  72. ncbi request reprint Membrane fatty acids, glutathione-peroxidase activity, and cation transport systems of erythrocytes and malondialdehyde production by platelets in Laurence Moon Barter Biedl syndrome
    R Corrocher
    Istituto di Patologia Medica, , Italy
    J Endocrinol Invest 12:475-81. 1989
    ....
  73. ncbi request reprint Oxidative damage and erythrocyte membrane transport abnormalities in thalassemias
    O Olivieri
    Department of Internal Medicine, University of Verona, Italy
    Blood 84:315-20. 1994
    ..Thus, oxidative damage represents an important factor in the increased activity of the K-Cl cotransport observed in thalassemias, and of the K+ loss observed in beta-thalassemia erythrocytes...
  74. pmc A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    Simonetta Friso
    Vitamin Metabolism Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 99:5606-11. 2002
    ..03) that is known to be solely represented in those individuals. These results indicate that the MTHFR C677T polymorphism influences DNA methylation status through an interaction with folate status...
  75. ncbi request reprint Association between four SNPs on chromosome 9p21 and myocardial infarction is replicated in an Italian population
    Gong Qing Shen
    Department of Molecular Cardiology, Center for Cardiovascular Genetics, Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    J Hum Genet 53:144-50. 2008
    ..These results indicate that chromosome 9p21 confers risk for development of MI in an Italian population...
  76. pmc An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction
    Gong Qing Shen
    Department of Molecular Cardiology, Lerner Research Institute, Center for Cardiovascular Genetics, Cleveland, OH 44195, USA
    Am J Hum Genet 81:780-91. 2007
    ..This extensive study, involving multiple independent populations, provides the first evidence that genetic variants in LRP8 may contribute to the development of premature and familial CAD and MI...
  77. ncbi request reprint Plasma aldosterone assays: comparison between chemiluminescence-based and RIA methods
    Francesca Pizzolo
    Clin Chem 52:1431-2. 2006
  78. ncbi request reprint Clinical heterogeneity of acquired hemophilia A: a description of 4 cases
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione, Azienda Ospedaliera di Verona
    Haematologica 90:ECR16. 2005
    ....
  79. ncbi request reprint Interaction of antibodies against cytomegalovirus with heat-shock protein 60 in pathogenesis of atherosclerosis
    Caterina Bason
    Department of Experimental Medicine, University of Genova, Genova, Italy
    Lancet 362:1971-7. 2003
    ..We postulated that cytomegalovirus infection might induce antibodies able to bind human HSP60 and to cause endothelial-cell damage...