G Niccoli

Summary

Affiliation: University of Foggia
Country: Italy

Publications

  1. doi request reprint Myocardial no-reflow in humans
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    J Am Coll Cardiol 54:281-92. 2009
  2. ncbi request reprint Association between inflammatory biomarkers and in-stent restenosis tissue features: an Optical Coherence Tomography Study
    Giampaolo Niccoli
    Cardiovascular Science Department, Sacred Heart University, L go Gemelli 8, 00168 Rome, Italy
    Eur Heart J Cardiovasc Imaging 15:917-25. 2014
  3. ncbi request reprint Evolving management of patients treated by drug-eluting stent: prevention of late events
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy Electronic address
    Cardiovasc Revasc Med 15:100-8. 2014
  4. ncbi request reprint Impact of Accuracy of Fractional Flow Reserve to Reduction of Microvascular Resistance After Intracoronary Adenosine in Patients With Angina Pectoris or Non-ST-Segment Elevation Myocardial Infarction
    Giampaolo Niccoli
    Department of Cardiovascular Medicine, Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy Electronic address
    Am J Cardiol 113:1461-7. 2014
  5. ncbi request reprint No-reflow reversibility: a study based on serial assessment of multiple biomarkers
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    J Cardiovasc Transl Res 6:798-807. 2013
  6. doi request reprint Incidence, time course and predictors of early vs. late target lesion revascularisation after everolimus-eluting stent implantation: a SPIRIT V substudy
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    EuroIntervention 9:353-9. 2013
  7. pmc INtimal hyPerplasia evAluated by oCT in de novo COROnary lesions treated by drug-eluting balloon and bare-metal stent (IN-PACT CORO): study protocol for a randomized controlled trial
    Francesco Burzotta
    Institute of Cardiology, Catholic University of the Sacred Heart, L, go Gemelli 8, 00168 Rome, Italy
    Trials 13:55. 2012
  8. ncbi request reprint No-reflow: incidence and detection in the cath-lab
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    Curr Pharm Des 19:4564-75. 2013
  9. ncbi request reprint Inflammatory mechanisms of adverse reactions to drug-eluting stents
    Rocco A Montone
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Curr Vasc Pharmacol 11:392-8. 2013
  10. doi request reprint Open-label, randomized, placebo-controlled evaluation of intracoronary adenosine or nitroprusside after thrombus aspiration during primary percutaneous coronary intervention for the prevention of microvascular obstruction in acute myocardial infarction: t
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    JACC Cardiovasc Interv 6:580-9. 2013

Detail Information

Publications94

  1. doi request reprint Myocardial no-reflow in humans
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    J Am Coll Cardiol 54:281-92. 2009
    ..Thus, in this review article, for the first time, we propose a personalized management of no-reflow on the basis of the assessment of the prevailing mechanisms of no-reflow operating in each patient...
  2. ncbi request reprint Association between inflammatory biomarkers and in-stent restenosis tissue features: an Optical Coherence Tomography Study
    Giampaolo Niccoli
    Cardiovascular Science Department, Sacred Heart University, L go Gemelli 8, 00168 Rome, Italy
    Eur Heart J Cardiovasc Imaging 15:917-25. 2014
    ..We assessed the association of optical coherence tomography (OCT) features of neointima with systemic levels of high-sensitivity C-reactive protein (hs-CRP) and eosinophil cationic protein (ECP) measured at the time of ISR detection...
  3. ncbi request reprint Evolving management of patients treated by drug-eluting stent: prevention of late events
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy Electronic address
    Cardiovasc Revasc Med 15:100-8. 2014
    ..Indeed, DES-related events may extend over this time, due to late events (late ISR and/or very late stent thrombosis). Prevention of late failure of DES may become a specific therapeutic target...
  4. ncbi request reprint Impact of Accuracy of Fractional Flow Reserve to Reduction of Microvascular Resistance After Intracoronary Adenosine in Patients With Angina Pectoris or Non-ST-Segment Elevation Myocardial Infarction
    Giampaolo Niccoli
    Department of Cardiovascular Medicine, Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy Electronic address
    Am J Cardiol 113:1461-7. 2014
    ..In conclusion, patients with non-STEMI and those with increased C-reactive protein levels show a lower reduction in MR after intracoronary adenosine-induced hyperemia, leading to FFR underestimation. ..
  5. ncbi request reprint No-reflow reversibility: a study based on serial assessment of multiple biomarkers
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    J Cardiovasc Transl Res 6:798-807. 2013
    ..01 and 0.044, respectively). Bigger ΔMPO, ΔCRP (increasing levels), and ΔAng-2 (decreasing levels) are associated with sustained no-reflow, thus they might have a role in no-reflow evolution. ..
  6. doi request reprint Incidence, time course and predictors of early vs. late target lesion revascularisation after everolimus-eluting stent implantation: a SPIRIT V substudy
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    EuroIntervention 9:353-9. 2013
    ....
  7. pmc INtimal hyPerplasia evAluated by oCT in de novo COROnary lesions treated by drug-eluting balloon and bare-metal stent (IN-PACT CORO): study protocol for a randomized controlled trial
    Francesco Burzotta
    Institute of Cardiology, Catholic University of the Sacred Heart, L, go Gemelli 8, 00168 Rome, Italy
    Trials 13:55. 2012
    ..Drug-eluting balloons are a promising tool to prevent restenosis after coronary angioplasty. Moreover, an increased knowledge of the pathophysiology of restenosis my help improve therapeutic strategies...
  8. ncbi request reprint No-reflow: incidence and detection in the cath-lab
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    Curr Pharm Des 19:4564-75. 2013
    ..In this article, we review indexes of no-reflow used both in the cath-lab and thereafter. ..
  9. ncbi request reprint Inflammatory mechanisms of adverse reactions to drug-eluting stents
    Rocco A Montone
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Curr Vasc Pharmacol 11:392-8. 2013
    ....
  10. doi request reprint Open-label, randomized, placebo-controlled evaluation of intracoronary adenosine or nitroprusside after thrombus aspiration during primary percutaneous coronary intervention for the prevention of microvascular obstruction in acute myocardial infarction: t
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    JACC Cardiovasc Interv 6:580-9. 2013
    ....
  11. doi request reprint Excimer laser coronary angioplasty with manual thrombus aspiration for a case of very late stent thrombosis of sirolimus-eluting stent
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    J Cardiovasc Med (Hagerstown) 13:830-2. 2012
    ..In these cases, excimer laser coronary angioplasty may be useful due to its ability to dissolve thrombus...
  12. doi request reprint Severity of coronary atherosclerosis in patients with a first acute coronary event: a diabetes paradox
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo F Vito 1, 00168 Rome, Italy
    Eur Heart J 34:729-41. 2013
    ..We aimed to compare coronary artery disease (CAD) at the time of a first acute coronary syndrome (ACS) in type II diabetic and non-diabetic patients by coronary angiography and by optical coherence tomography (OCT)...
  13. ncbi request reprint Microvascular obstruction after primary percutaneous coronary intervention: pathogenesis, diagnosis and prognostic significance
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli 8, Rome, Italy
    Curr Vasc Pharmacol 11:245-62. 2013
    ....
  14. doi request reprint Serum levels of γ-glutamyltransferase and progression of coronary atherosclerosis
    Giampaolo Niccoli
    Department of Cardiovascular Medicine, Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Coron Artery Dis 24:40-7. 2013
    ..Serum levels of γ-glutamyltransferase (GGT), a marker of oxidative stress, predict the risk of cardiovascular events. However, the role of GGT levels in the progression of coronary ATS has never been established...
  15. ncbi request reprint Late (3 years) follow-up of successful versus unsuccessful revascularization in chronic total coronary occlusions treated by drug eluting stent
    Giampaolo Niccoli
    Institute of Cardiology, Sacro Cuore Catholic University, Rome, Italy
    Am J Cardiol 110:948-53. 2012
    ....
  16. ncbi request reprint Impact of gender on clinical outcomes after mTOR-inhibitor drug-eluting stent implantation in patients with first manifestation of ischaemic heart disease
    Giampaolo Niccoli
    Istituto di Cardiologia, Catholic University of Sacred Heart, Rome, Italy
    Eur J Prev Cardiol 19:914-26. 2012
    ..We aimed to assess the impact of gender on clinical outcomes in a consecutive series of patients at first manifestation of coronary artery disease (CAD) undergoing PCI with mTOR-inhibitor DES...
  17. doi request reprint Impact of electronegative low-density lipoprotein on angiographic coronary atherosclerotic burden
    Giampaolo Niccoli
    Istituto di Cardiologia, Facolta di Medicina e Chirurgia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Atherosclerosis 223:166-70. 2012
    ..Low density lipoproteins (LDL) with an electronegative charge [LDL(-)] may cause endothelial injury. We assessed the association between serum LDL(-) levels and coronary artery disease (CAD) severity...
  18. doi request reprint Predictors of thromboxane levels in patients with non-ST-elevation acute coronary syndromes on chronic aspirin therapy
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    Thromb Haemost 108:133-9. 2012
    ..This finding suggests that additional efforts should be made to lower TxA2 levels in patients with widespread coronary artery disease...
  19. doi request reprint Eosinophil cationic protein and clinical outcome after bare metal stent implantation
    Giampaolo Niccoli
    Institute of Cardiology, Department of Internal Medicine and Allergology, Catholic University of the Sacred Heart, Rome, Italy
    Atherosclerosis 215:166-9. 2011
    ..we assessed the association between baseline eosinophil cationic protein (ECP) levels, a sensitive marker of eosinophil activation, and clinical outcome in patients undergoing bare metal stent (BMS) implantation...
  20. doi request reprint Coronary atherosclerotic burden in patients with infection by CagA-positive strains of Helicobacter pylori
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of Sacred Heart, Rome, Italy
    Coron Artery Dis 21:217-21. 2010
    ..Nevertheless, whether CagA-positivity is associated with more extensive or severe atherosclerotic coronary burden has never been studied...
  21. doi request reprint Prevention and treatment of no-reflow
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Acute Card Care 12:81-91. 2010
    ..Serial assessment of myocardial perfusion showed that in up to 50% of patients no-reflow is spontaneously reversible. This finding may open new scenarios, as mechanisms of reversibility may become future therapeutic targets...
  22. doi request reprint Ethanol abolishes ischemic preconditioning in humans
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    J Am Coll Cardiol 51:271-5. 2008
    ..This study sought to assess the effect of acute alcohol intake on ischemic preconditioning (IPC) in humans using the clinical model of 2 sequential balloon inflations during a percutaneous coronary intervention (PCI)...
  23. doi request reprint The evolving role of inflammatory biomarkers in risk assessment after stent implantation
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    J Am Coll Cardiol 56:1783-93. 2010
    ..In this report, we review the evolving role of inflammatory biomarkers in predicting the risk of ISR and stent thrombosis...
  24. doi request reprint Eosinophil cationic protein: A new biomarker of coronary atherosclerosis
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli 8, 00168 Rome, Italy
    Atherosclerosis 211:606-11. 2010
    ..We aimed at assessing the role of eosinophil cationic protein (ECP), a sensitive marker of eosinophil activation, and C-reactive protein (CRP) in coronary artery disease (CAD)...
  25. doi request reprint Effect of chronic Aspirin therapy on angiographic thrombotic burden in patients admitted for a first ST-elevation myocardial infarction
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Am J Cardiol 105:587-91. 2010
    ....
  26. doi request reprint Randomized evaluation of intracoronary nitroprusside vs. adenosine after thrombus aspiration during primary percutaneous coronary intervention for the prevention of no-reflow in acute myocardial infarction: the REOPEN-AMI study protocol
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Italy
    J Cardiovasc Med (Hagerstown) 10:585-92. 2009
    ....
  27. doi request reprint Pre-intervention eosinophil cationic protein serum levels predict clinical outcomes following implantation of drug-eluting stents
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Eur Heart J 30:1340-7. 2009
    ..We aimed at assessing the association between baseline levels of eosinophil cationic protein (ECP), a marker of eosinophil activation, and recurrence of clinical events in a consecutive series of patients who underwent DES implantation...
  28. ncbi request reprint [Association between ethanol intake and ischemic heart disease]
    Giampaolo Niccoli
    Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Roma
    Recenti Prog Med 99:565-71. 2008
    ..In this review, we highlight the recent epidemiological and experimental evidences regarding the specific benefits and risks of ethanol in the setting of ischemic heart disease...
  29. doi request reprint Coronary bifurcation lesions: to stent one branch or both? A meta-analysis of patients treated with drug eluting stents
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, 00168 Rome, Italy
    Int J Cardiol 139:80-91. 2010
    ....
  30. doi request reprint Plasma levels of thromboxane A2 on admission are associated with no-reflow after primary percutaneous coronary intervention
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo F Vito 1, 00168 Rome, Italy
    Eur Heart J 29:1843-50. 2008
    ..We sought to investigate whether baseline plasma levels of TXA2 are associated with coronary no-reflow after primary percutaneous coronary intervention (PPCI)...
  31. ncbi request reprint Cystatin C is associated with an increased coronary atherosclerotic burden and a stable plaque phenotype in patients with ischemic heart disease and normal glomerular filtration rate
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Atherosclerosis 198:373-80. 2008
    ..Cystatin C (Cys-C) is an accurate marker of renal function. Recent studies have shown that serum Cys-C levels predict the risk of cardiovascular events. The causes of this association, however, are largely unknown...
  32. ncbi request reprint Predictive value of preintervention C-reactive protein on clinical outcome after directional coronary atherectomy followed by stent implantation
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Cardiovasc Revasc Med 8:156-60. 2007
    ..Thus, we assessed the influence of preprocedural CRP serum levels on the recurrence of cardiac events after DCA followed by bare metal stent implantation...
  33. ncbi request reprint Drug eluting stent and coronary chronic total occlusions
    G Niccoli
    Institute of Cardiology, Sacro Cuore Catholic University, Rome, Italy
    Minerva Cardioangiol 59:271-84. 2011
    ..The aim of this article is to review the current stage of knowledge on the application of stents in the treatment of CTO, with a particular attention to DES use and to DES-related challenges...
  34. ncbi request reprint Independent prognostic value of C-reactive protein and coronary artery disease extent in patients affected by unstable angina
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Largo F Vito 1, 00168 Rome, Italy
    Atherosclerosis 196:779-85. 2008
    ..We tested this hypothesis in a selected population of patients with unstable angina undergoing coronary angiography...
  35. ncbi request reprint Endothelin-1 and acute myocardial infarction: a no-reflow mediator after successful percutaneous myocardial revascularization
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, 00168 Rome, Italy
    Eur Heart J 27:1793-8. 2006
    ..We aimed to investigate the relationship between systemic ET-1 plasma levels and no-reflow in a group of AMI patients treated by primary PCI...
  36. ncbi request reprint Baseline systemic inflammatory status and no-reflow phenomenon after percutaneous coronary angioplasty for acute myocardial infarction
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Int J Cardiol 117:306-11. 2007
    ..However, whether it plays a role in the no-reflow phenomenon occurring in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) is unknown...
  37. doi request reprint [Clinical value of inflammatory biomarkers after stent implantation]
    Giampaolo Niccoli
    Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Largo, Roma, Italy
    G Ital Cardiol (Rome) 12:635-44. 2011
    ..In this review, the evolving role of inflammatory biomarkers in predicting adverse reactions after stent implantation is discussed, underlying therapeutic and clinical consequences for the management of patients receiving a BMS or a DES...
  38. doi request reprint Angiographic patterns of myocardial reperfusion after primary angioplasty and ventricular remodeling
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Coron Artery Dis 22:507-14. 2011
    ..We aimed at assessing in-hospital evolution of angiographic no reflow, predictors of its reversibility, and its impact on LV function at follow-up (FU)...
  39. doi request reprint A complex case of angulated and bifurcated lesion facilitated by excimer laser coronary angioplasty
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    J Interv Cardiol 24:514-7. 2011
    ....
  40. doi request reprint New strategies for the management of no-reflow after primary percutaneous coronary intervention
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Expert Rev Cardiovasc Ther 9:615-30. 2011
    ..In this article, we concentrate on the major preventive and therapeutic approaches currently available for the management of the no-reflow phenomenon...
  41. pmc Dynamic collateral coronary circulation: angiographic evidence
    Giampaolo Niccoli
    Heart 93:487. 2007
  42. ncbi request reprint Long drug-eluting stent implantation for a diffusely diseased right internal mammary artery
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University, Rome, Italy
    J Cardiovasc Med (Hagerstown) 8:381-3. 2007
    ..We describe a case of long drug-eluting stent implantation for a diffusely diseased right internal mammary artery...
  43. ncbi request reprint The complex link between oxidised low-density lipoprotein and unstable angina
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University, Rome, Italy
    J Cardiovasc Med (Hagerstown) 8:387-91. 2007
    ..We also assessed the correlation between plaque or plasma ox-LDL and angiographic complex stenosis morphology...
  44. doi request reprint Endogenous serum erythropoietin and no-reflow in patients with ST-elevation myocardial infarction
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University, Rome, Italy
    Eur J Clin Invest 41:1210-9. 2011
    ..We studied the association between circulating endogenous EPO and no-reflow in patients with first ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI)...
  45. ncbi request reprint Baseline C-reactive protein serum levels and in-stent restenosis pattern after m-TOR inhibitors drug-eluting stent implantation
    Giampaolo Niccoli
    Catholic University of the Sacred Heart, Cardiovascular Medicine, L go F Vito 1, Rome 00168, Italy
    J Invasive Cardiol 23:16-20. 2011
    ..A diffuse pattern of in-stent restenosis (ISR) has been shown to have a worse prognosis when compared to a focal pattern. It is still unknown whether baseline C-reactive protein (CRP) levels predict ISR pattern...
  46. doi request reprint EuroSCORE as predictor of in-hospital mortality after percutaneous coronary intervention
    E Romagnoli
    Institute of Cardiology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Heart 95:43-8. 2009
    ..Thus, we sought to assess the European System for Cardiac Operative Risk Evaluation (EuroSCORE) validity to predict in-hospital mortality after percutaneous coronary intervention (PCI). Design,..
  47. ncbi request reprint Feasibility of sequential thrombus aspiration and filter distal protection in the management of very high thrombus burden lesions
    Francesco Burzotta
    Catholic University of the Sacred Heart, Cardiology Department, Rome, Italy
    J Invasive Cardiol 19:317-23. 2007
    ..A series of thrombectomy and distal filter devices have been developed to limit distal embolization during percutaneous coronary interventions (PCI)...
  48. ncbi request reprint Ticlopidine and aspirin fail to suppress the increased platelet aggregability that follows percutaneous coronary interventions
    D Fischetti
    Institute of Cardiology, Catholic University, Rome, Italy
    J Thromb Thrombolysis 10:265-9. 2000
    ..03). Ticlopidine and aspirin reduce whole-blood platelet aggregability compared with aspirin alone but fail to suppress the increased aggregability that occurs 24 hours after PTCA...
  49. ncbi request reprint Coronary risk factors: new perspectives
    G Niccoli
    Istituto di Cardiologia, Universita Cattolica, Roma, Italy
    Int J Epidemiol 30:S41-7. 2001
    ....
  50. ncbi request reprint Adjunctive devices in primary or rescue PCI: a meta-analysis of randomized trials
    Francesco Burzotta
    Institute of Cardiology, Catholic University of the Sacred Heart, Via Prati Fiscali 158, 00141 Rome, Italy
    Int J Cardiol 123:313-21. 2008
    ....
  51. ncbi request reprint Autoantibodies against oxidized low density lipoproteins in patients with stable angina, unstable angina or peripheral vascular disease; pathophysiological implications
    C Monaco
    Istituto di Cardiologia, , Rome, Italy
    Eur Heart J 22:1572-7. 2001
    ..CONCLUSION: The autoimmune response to oxLDL is likely to play an important role in atherogenesis but not in precipitating acute coronary syndromes...
  52. doi request reprint CagA antigen of Helicobacter pylori and coronary instability: insight from a clinico-pathological study and a meta-analysis of 4241 cases
    Francesco Franceschi
    Emergency Department, Catholic University of Sacred Heart, Rome, Italy
    Atherosclerosis 202:535-42. 2009
    ..pylori). The role of CagA antigen in coronary instability is unknown. We performed a clinico-pathological study and a meta-analysis in the attempt to shed new light on this complex issue...
  53. ncbi request reprint Manual thrombus-aspiration improves myocardial reperfusion: the randomized evaluation of the effect of mechanical reduction of distal embolization by thrombus-aspiration in primary and rescue angioplasty (REMEDIA) trial
    Francesco Burzotta
    Institute of Cardiology, Catholic University, Rome, Italy
    J Am Coll Cardiol 46:371-6. 2005
    ..The aim of this study was to evaluate the use of a new manual thrombus-aspirating device in unselected patients with ST-segment elevation acute myocardial infarction (STEMI) undergoing urgent percutaneous coronary intervention (PCI)...
  54. doi request reprint Radial artery intima-media ratio predicts presence of coronary thin-cap fibroatheroma: a frequency domain-optical coherence tomography study
    L Di Vito
    Department of Cardiovascular Medicine, Policlinico A Gemelli, Catholic University of the Sacred Heart, Rome, Italy
    Int J Cardiol 168:1917-22. 2013
    ..Peripheral arterial disease is a risk factor for cardiac mortality but pathophysiologic mechanisms linking atherosclerosis of peripheral arteries with coronary events in the single patient have not been established...
  55. ncbi request reprint Sirolimus, Tacrolimus and Zotarolimus eluting stents to treat bifurcated lesions: a 7-month clinical outcome comparison
    S Brugaletta
    Department of Cardiology, Catholic University, Rome, Italy
    Minerva Cardioangiol 56:35-42. 2008
    ..The aim of this study was to evaluate the long-term clinical outcomes of patients with bifurcated lesions treated by 3 different DES...
  56. doi request reprint Renal artery stenting in patients with chronic ischemic heart disease
    Carlo Trani
    Department of Cardiology, Catholic University of the Sacred Heart, Viale G Rossini 74, Rome, Italy
    Catheter Cardiovasc Interv 76:26-34. 2010
    ..To investigate the role of renal stenting in selected patients with chronic ischemic heart disease and renal artery stenosis...
  57. ncbi request reprint A pilot study with a new, rapid-exchange, thrombus-aspirating device in patients with thrombus-containing lesions: the Diver C.E. study
    Francesco Burzotta
    Institute of Cardiology, Catholic University, Rome, Italy
    Catheter Cardiovasc Interv 67:887-93. 2006
    ..Thus, interventional techniques able to reduce thrombus burden at the culprit vessel might improve final myocardial reperfusion...
  58. doi request reprint Predictive value of C-reactive protein after drug-eluting stent implantation
    Rocco Antonio Montone
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Future Cardiol 6:167-79. 2010
    ....
  59. ncbi request reprint Directional atherectomy before stenting versus stenting alone in percutaneous coronary interventions: a meta-analysis
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University, Largo F Vito 1 00168 Rome, Italy
    Int J Cardiol 112:178-83. 2006
    ..The higher prevalence of early MACEs with DCA before stenting, however, is disturbing and probably related to distal embolization...
  60. ncbi request reprint Effect of primary percutaneous coronary intervention versus thrombolysis on ventricular arrhythmias and heart rate variability in acute myocardial infarction
    Claudio Larosa
    Institute of Cardiology, Catholic University, Rome, Italy
    Ital Heart J 6:629-33. 2005
    ..Primary percutaneous coronary intervention (PCI) has recently become the treatment of choice for AMI, but it is still unknown whether it has favorable effects on these prognostic variables...
  61. ncbi request reprint Outcome of patients treated by a novel thin-strut cobalt-chromium stent in the drug-eluting stent era: Results of the SKICE (Skylor in real world practice) registry
    Francesco Burzotta
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Catheter Cardiovasc Interv 73:457-65. 2009
    ..To investigate the outcome of patients undergoing percutaneous coronary interventions (PCI) with implantation of a new thin-strut cobalt-chromium bare-metal-stent (BMS) in the drug-eluting-stent (DES) era...
  62. ncbi request reprint Glycoprotein IIB/IIIA inhibitor to reduce postpercutaneous coronary intervention myonecrosis and improve coronary flow in diabetics: the 'OPTIMIZE-IT' pilot randomized study
    Giovanni Paolo Talarico
    Institute of Cardiology, Catholic University, Rome, Italy
    J Cardiovasc Med (Hagerstown) 10:245-51. 2009
    ..However, the efficacy of small-molecule IIb/IIIa receptor inhibitors to improve microvascular perfusion in stable diabetic patients undergoing elective PCI has not been specifically investigated...
  63. ncbi request reprint Outcome of overlapping heterogenous drug-eluting stents and of overlapping drug-eluting and bare metal stents
    Francesco Burzotta
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Am J Cardiol 99:364-8. 2007
    ..Overlap between SESs and PESs in this very preliminary report was associated with no specific adverse event...
  64. ncbi request reprint Inflammatory predictors of mortality in the Scandinavian Simvastatin Survival Study
    Filippo Crea
    Istituto di Cardiologia, Universita Cattolica, Rome, Italy
    Clin Cardiol 25:461-6. 2002
    ..The predictive value of specific markers of infection and autoimmunity for coronary events, such as the effects of statins on inflammation, is still controversial...
  65. doi request reprint Different apparent prognostic value of hsCRP in type 2 diabetic and nondiabetic patients with acute coronary syndromes
    Luigi M Biasucci
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Clin Chem 55:365-8. 2009
    ..We evaluated the prognostic role of CRP separately in diabetic and nondiabetic patients with ACS...
  66. doi request reprint Association between C-reactive protein and angiographic restenosis after bare metal stents: an updated and comprehensive meta-analysis of 2747 patients
    Giuseppe Ferrante
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Cardiovasc Revasc Med 9:156-65. 2008
    ..Previous studies have shown conflicting results about the relationship between baseline C-reactive protein (CRP) and restenosis after stenting with bare metal stent (BMS)...
  67. ncbi request reprint A complex case of right coronary artery chronic total occlusion treated by a successful multi-step Japanese approach
    Giampaolo Niccoli
    Catholic University of the Sacred Heart, Rome, Italy
    J Invasive Cardiol 18:E230-3. 2006
    ..We describe a case of successful reopening of a chronically occluded right coronary artery using a retrograde wire as a landmark of the true lumen and a novel penetration device (Tornus, Ashai) to facilitate balloon and stent deployment...
  68. ncbi request reprint Angiographic evaluation of the effect of intracoronary abciximab administration in patients undergoing urgent PCI
    Enrico Romagnoli
    Institute of Cardiology, Catholic University, Largo A Gemelli 8, 00168 Rome, Italy
    Int J Cardiol 105:250-5. 2005
    ..c.) administration of a systemic bolus dose of abciximab during PCI may increase the efficacy of this antiplatelet drug. However, the effect of i.c. abciximab on coronary angiographic flow has been not clarified...
  69. doi request reprint Feasibility and long-term safety of elective Impella-assisted high-risk percutaneous coronary intervention: a pilot two-centre study
    Francesco Burzotta
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    J Cardiovasc Med (Hagerstown) 9:1004-10. 2008
    ..We evaluated the acute and long-term results of the use of a new intracardiac microaxial pump, the Impella Recover LP 2.5, during elective high-risk percutaneous coronary interventions in a two-centre registry...
  70. doi request reprint Effect of low doses of alcohol on the warm-up phenomenon in patients with stable angina pectoris
    Leonardo Marinaccio
    Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Am J Cardiol 102:146-9. 2008
    ..In conclusion, our data show that, in stable CAD patients, the acute intake of low doses of alcohol does not significantly influence IPC, as expressed by the warm-up phenomenon on exercise stress testing...
  71. ncbi request reprint Urgent PCI in patients with stent thrombosis: an observational single-center study comparing thrombus aspiration and standard PCI
    Maria De Vita
    Institute of Cardiology, Catholic University, Via B Barbiellini Amidei, 80, 00168, Rome, Italy
    J Invasive Cardiol 20:161-5. 2008
    ..Due to the high thrombus burden present in ST, the use of thrombus aspiration (TA) may enhance the angiographic results by limiting distal embolization...
  72. doi request reprint Outcomes of the tacrolimus drug-eluting Janus stent: a prospective two-centre registry in high-risk patients
    Enrico Romagnoli
    Department of Cardiovascular Disease, Catholic University, Campobasso, Italy
    J Cardiovasc Med (Hagerstown) 9:589-94. 2008
    ..Thus, we performed a prospective registry of consecutive, unselected patients receiving this new DES...
  73. doi request reprint Comparison of the transradial and transfemoral approaches for coronary angiographic evaluation in patients with internal mammary artery grafts
    Francesco Burzotta
    Institute of Cardiology, Catholic University, Rome, Italy
    J Cardiovasc Med (Hagerstown) 9:263-6. 2008
    ..Therefore, the aim of this study was to compare the transradial and transfemoral approaches in patients with previous coronary artery bypass graft (CABG) surgery using the left internal mammary artery (IMA)...
  74. ncbi request reprint Acute myocardial infarction interventional procedures: primary percutaneous coronary intervention versus facilitated percutaneous coronary intervention, rescue angioplasty, rescue excimer laser
    A G Rebuzzi
    Department of Cardiology, Agostino Gemelli Polyclinic, Catholic University, Rome, Italy
    Minerva Cardioangiol 55:73-82. 2007
    ..However, rescue PCI is not associated with a better long-term clinical outcome. Laser thrombectomy before PCI could be a useful additional strategy which might be compared to standard stenting in future randomized studies...
  75. ncbi request reprint Relation of myocardial blush grade to microvascular perfusion and myocardial infarct size after primary or rescue percutaneous coronary intervention
    Italo Porto
    Department of Cardiovascular Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Am J Cardiol 99:1671-3. 2007
    ..Moreover, the mechanisms of ST resolution should be searched for at the cellular level...
  76. ncbi request reprint Postoperative coronary artery spasm complicating aortic valve replacement: implications for identification and treatment
    Claudio Pragliola
    Institute of Cardiac Surgery, Catholic University of Rome, Rome, Italy
    Ann Thorac Surg 83:670-2. 2007
    ..The spasm was demonstrated at coronary angiography and was resolved with the intracoronary infusion of nitrates and antiarrhythmics...
  77. doi request reprint Dynamic thrombosis associated with bare-metal stent malapposition in a patient with hyperhomocysteinemia
    Domenico D'Amario
    Institute of Cardiology, Catholic University, Rome, Italy
    J Cardiovasc Med (Hagerstown) 9:427-9. 2008
  78. ncbi request reprint High telomerase activity in neutrophils from unstable coronary plaques
    Maria Lucia Narducci
    Institute of Cardiology, Catholic University of Sacred Heart, Rome, Italy
    J Am Coll Cardiol 50:2369-74. 2007
    ..We evaluated telomerase activity in circulating polymorphonuclear neutrophils (PMN) and in PMN isolated from coronary atherosclerotic plaques by a novel approach...
  79. doi request reprint Effect of intensive vs standard statin therapy on endothelial progenitor cells and left ventricular function in patients with acute myocardial infarction: Statins for regeneration after acute myocardial infarction and PCI (STRAP) trial
    Antonio Maria Leone
    Institute of Cardiology and Institute of Haematology, Catholic University of the Sacred Heart, Rome, Italy
    Int J Cardiol 130:457-62. 2008
    ....
  80. ncbi request reprint Usefulness of granulocyte colony-stimulating factor in patients with a large anterior wall acute myocardial infarction to prevent left ventricular remodeling (the rigenera study)
    Antonio Maria Leone
    Institute of Cardiology, Catholic University of Sacred Heart, Rome, Italy
    Am J Cardiol 100:397-403. 2007
    ..In conclusion, G-CSF prevents unfavorable LV remodeling and improves LV function in patients with large anterior wall AMI and decreased LV ejection fraction after successful percutaneous coronary intervention...
  81. ncbi request reprint Use of a second buddy wire during percutaneous coronary interventions: a simple solution for some challenging situations
    Francesco Burzotta
    Institute of Cardiology, Catholic University, Via Prati Fiscali 158, 00141, Rome, Italy
    J Invasive Cardiol 17:171-4. 2005
    ..Because of its simplicity, low cost, and availability, the use of a buddy wire should be considered when dealing with the aforementioned conditions during PCI procedures...
  82. doi request reprint Comparison of the effects of ramipril versus telmisartan on high-sensitivity C-reactive protein and endothelial progenitor cells after acute coronary syndrome
    Italo Porto
    Department of Cardiovascular Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Am J Cardiol 103:1500-5. 2009
    ..In conclusion, telmisartan shows a more potent anti-inflammatory effect than ramipril after an ACS. The 2 drugs do not show a differential effect on endothelial progenitor cell mobilization...
  83. doi request reprint Predictors of impaired heart rate variability and clinical outcome in patients with acute myocardial infarction treated by primary angioplasty
    Claudio Larosa
    Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    J Cardiovasc Med (Hagerstown) 9:76-80. 2008
    ..To investigate the determinants and prognostic value of heart rate variability (HRV) in acute myocardial infarction (AMI) patients treated by percutaneous coronary intervention (PCI)...
  84. ncbi request reprint Provisional TAP-stenting strategy to treat bifurcated lesions with drug-eluting stents: one-year clinical results of a prospective registry
    Francesco Burzotta
    Institute of Cardiology, Catholic University of the Sacred Heart, Via Prati Fiscali 158, 00141 Rome, Italy
    J Invasive Cardiol 21:532-7. 2009
    ..To assess the clinical outcome of unselected patients undergoing drug-eluting stent (DES) implantation on bifurcated lesions using a "provisional T And small Protrusion (TAP)" stenting strategy...
  85. doi request reprint Nonconventional use of coronary guidewires for ECG recording and emergency pacing
    Italo Porto
    Department of Cardiovascular Medicine, Catholic University of the Sacred Heart, Rome, Italy
    J Cardiovasc Med (Hagerstown) 9:1222-8. 2008
    ..The technical details of these techniques are elucidated and their usefulness as clinical and research tools is discussed, with an emphasis on possible future applications...
  86. ncbi request reprint Superior vena cava thrombosis treated by angioplasty and stenting in a cirrhotic patient with peritoneovenous shunt
    Lorenzo Leggio
    Institutes of Internal Medicine, Catholic University of Rome, Rome, Italy
    Ann Thorac Cardiovasc Surg 14:60-2. 2008
    ..The patient died in June 2006 due to severe liver function impairment and hepato-renal syndrome. The present case shows that percutaneous transluminal angioplasty represents a good choice for primary intervention...
  87. ncbi request reprint Attempted retrograde reopening of an occluded left main stent
    Giampaolo Niccoli
    Istituto di Cardiologia Università Cattolica del Sacro Cuore Policlinico A Gemelli Largo A Gemelli, 8 00168 Roma
    Ital Heart J 3:483-5. 2002
    ..Although this case was unsuccessful it demonstrates how technological developments are allowing interventionists to tackle a vast range of challenging cases, which only few years ago would have been considered impossible...
  88. ncbi request reprint Diffuse saphenous vein graft spasm
    Vaishali Ashar
    Department of Cardiology, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9ES, United Kingdom
    J Invasive Cardiol 16:667-8. 2004
  89. ncbi request reprint Instability mechanisms in unstable angina according to baseline serum levels of C-reactive protein: the role of thrombosis, fibrinolysis and atherosclerotic burden
    Giampaolo Niccoli
    Int J Cardiol 122:245-7. 2007
    ....
  90. ncbi request reprint Different effect of percutaneous and surgical coronary revascularization on cardiac autonomic function and inflammation in patients with stable angina
    Pasquale Santangeli
    Int J Cardiol 127:269-70. 2008
    ..Thus, while confirming the presence of a relation between cardiac autonomic dysfunction and inflammation in CAD patients, our data show that the association is lost after revascularization procedures...
  91. ncbi request reprint Delayed stenting of a thrombotic saphenous vein graft after intravenous tirofiban pretreatment
    Giampaolo Niccoli
    Int J Cardiol 110:108-9. 2006
  92. doi request reprint Carotid bruits and cardiovascular death or myocardial infarction
    Giuseppe Ferrante
    Lancet 372:534; author reply 534-5. 2008
  93. ncbi request reprint Extensive right coronary artery dissection following cutting balloon treatment of in-stent restenosis
    Giampaolo Niccoli
    Department of Cardiology, John Radcliffe Hospital, Headington, Oxford, United Kingdom
    J Invasive Cardiol 14:209-11. 2002
  94. ncbi request reprint A case of fatal stent thrombosis after Carbostent implantation: is clopidogrel alone antiplatelet therapy a safe alternative to aspirin alone antiplatelet therapy?
    Giampaolo Niccoli
    Int J Cardiol 114:279-81. 2007
    ..At the present time the choice between PCI at high risk of stent thrombosis followed by low risk cancer resection and cancer resection at high risk of peri-operative myocardial infarction followed by low risk PCI remains difficult...