Daniela Negrini

Summary

Affiliation: University of Insubria
Country: Italy

Publications

  1. doi request reprint Pleural function and lymphatics
    D Negrini
    Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy
    Acta Physiol (Oxf) 207:244-59. 2013
  2. pmc Lymphatic anatomy and biomechanics
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    J Physiol 589:2927-34. 2011
  3. doi request reprint The role of proteoglycans in pulmonary edema development
    Daniela Negrini
    Departmentof Experimental and Clinical Biomedical Sciences, University of Insubria, via J H Dunant 5, 21100, Varese, Italy
    Intensive Care Med 34:610-8. 2008
  4. pmc Interstitial exclusion of albumin in rabbit lung during development of pulmonary oedema
    Daniela Negrini
    Department of Biomedical, Experimental and Clinical Sciences, University of Insubria, Varese, 21100, Italy
    J Physiol 548:907-17. 2003
  5. ncbi request reprint Interstitial matrix and transendothelial fluxes in normal lung
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, Via Dunant 5, 21100, Varese, Italy
    Respir Physiol Neurobiol 159:301-10. 2007
  6. pmc Lymph flow modulation: the tricks of a performant machinery
    Daniela Negrini
    Department of Experimental and Clinical Biomedical Sciences, University of Insubria, via J H Dunant 5, 21100 Varese, Italy
    J Physiol 575:687. 2006
  7. ncbi request reprint Transmural pressure during cardiogenic oscillations in rodent diaphragmatic lymphatic vessels
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, Varese, Italy
    Lymphat Res Biol 2:69-81. 2004
  8. ncbi request reprint Differential degradation of matrix proteoglycans and edema development in rabbit lung
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, 21100, Varese, Italy
    Am J Physiol Lung Cell Mol Physiol 290:L470-7. 2006
  9. ncbi request reprint Interstitial exclusion of albumin in rabbit lung measured with the continuous infusion method in combination with the wick technique
    Daniela Negrini
    Department of Biomedical, Experimental Clinical Sciences, University of Insubria, Varese, 21100, Italy
    Microcirculation 10:153-65. 2003
  10. doi request reprint Impact of mechanical ventilation and fluid load on pulmonary glycosaminoglycans
    Andrea Moriondo
    Dept Surgical and Morphological Sciences, University of Insubria, Varese, Italy
    Respir Physiol Neurobiol 181:308-20. 2012

Collaborators

Detail Information

Publications19

  1. doi request reprint Pleural function and lymphatics
    D Negrini
    Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy
    Acta Physiol (Oxf) 207:244-59. 2013
    ....
  2. pmc Lymphatic anatomy and biomechanics
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    J Physiol 589:2927-34. 2011
    ....
  3. doi request reprint The role of proteoglycans in pulmonary edema development
    Daniela Negrini
    Departmentof Experimental and Clinical Biomedical Sciences, University of Insubria, via J H Dunant 5, 21100, Varese, Italy
    Intensive Care Med 34:610-8. 2008
    ..The loss of the PGs regulatory functions compromises the protective role of the tissue solid matrix progressively leading to interstitial and eventually severe lung edema...
  4. pmc Interstitial exclusion of albumin in rabbit lung during development of pulmonary oedema
    Daniela Negrini
    Department of Biomedical, Experimental and Clinical Sciences, University of Insubria, Varese, 21100, Italy
    J Physiol 548:907-17. 2003
    ..23 +/- 0.01, 33.2 % of the control value. Data indicate that, at variance with what is observed in tissues like skin and muscle, pulmonary Fe,a is highly sensitive to tissue fluid content...
  5. ncbi request reprint Interstitial matrix and transendothelial fluxes in normal lung
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, Via Dunant 5, 21100, Varese, Italy
    Respir Physiol Neurobiol 159:301-10. 2007
    ....
  6. pmc Lymph flow modulation: the tricks of a performant machinery
    Daniela Negrini
    Department of Experimental and Clinical Biomedical Sciences, University of Insubria, via J H Dunant 5, 21100 Varese, Italy
    J Physiol 575:687. 2006
  7. ncbi request reprint Transmural pressure during cardiogenic oscillations in rodent diaphragmatic lymphatic vessels
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, Varese, Italy
    Lymphat Res Biol 2:69-81. 2004
    ..To elucidate these aspects, the micropuncture technique was used to record interstitial (P(int)) and intralymphatic pressure (P(lymph)) simultaneously in the diaphragmatic lymphatic plexus draining the pleural cavity...
  8. ncbi request reprint Differential degradation of matrix proteoglycans and edema development in rabbit lung
    Daniela Negrini
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, 21100, Varese, Italy
    Am J Physiol Lung Cell Mol Physiol 290:L470-7. 2006
    ....
  9. ncbi request reprint Interstitial exclusion of albumin in rabbit lung measured with the continuous infusion method in combination with the wick technique
    Daniela Negrini
    Department of Biomedical, Experimental Clinical Sciences, University of Insubria, Varese, 21100, Italy
    Microcirculation 10:153-65. 2003
    ..To determine albumin exclusion from the pulmonary perivascular interstitium by using the continuous infusion methods coupled with direct samples of pulmonary interstitial fluid via the wick technique...
  10. doi request reprint Impact of mechanical ventilation and fluid load on pulmonary glycosaminoglycans
    Andrea Moriondo
    Dept Surgical and Morphological Sciences, University of Insubria, Varese, Italy
    Respir Physiol Neurobiol 181:308-20. 2012
    ..When combined to mechanical ventilation, fluid load might exacerbate edema development and lung injury...
  11. pmc Regional recruitment of rat diaphragmatic lymphatics in response to increased pleural or peritoneal fluid load
    Andrea Moriondo
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    J Physiol 579:835-47. 2007
    ....
  12. doi request reprint Kinetics of fluid flux in the rat diaphragmatic submesothelial lymphatic lacunae
    Andrea Moriondo
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, Varese 21100, Italy
    Am J Physiol Heart Circ Physiol 295:H1182-H1190. 2008
    ....
  13. ncbi request reprint Proteoglycan fragmentation and respiratory mechanics in mechanically ventilated healthy rats
    Andrea Moriondo
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    J Appl Physiol 103:747-56. 2007
    ....
  14. doi request reprint Extracellular matrix and mechanical ventilation in healthy lungs: back to baro/volotrauma?
    Paolo Pelosi
    Department of Environment, Health, and Safety, University of Insubria Circolo and Fondazione Macchi Hospital, Varese, Italy
    Curr Opin Crit Care 14:16-21. 2008
    ..The aim of this review is to describe the role of mechanical ventilation on pulmonary extracellular matrix structure and function...
  15. pmc Tissue contribution to the mechanical features of diaphragmatic initial lymphatics
    Andrea Moriondo
    Department of Experimental and Clinical Biomedical Sciences, Universita degli Studi dell Insubria, 21100 Varese, Italy
    J Physiol 588:3957-69. 2010
    ....
  16. ncbi request reprint Transmural pressure in rat initial subpleural lymphatics during spontaneous or mechanical ventilation
    Andrea Moriondo
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    Am J Physiol Heart Circ Physiol 289:H263-9. 2005
    ..1 +/- 1.8 mmHg). Therefore, data suggest that local tissue stress associated with the active contraction of respiratory muscles is required to support an efficient lymphatic drainage from the thoracic tissues...
  17. ncbi request reprint The extracellular matrix of the lung and its role in edema formation
    Paolo Pelosi
    Servizio di Anestesia B, Department of Ambient, Health and Safety, University of Insubria, and Ospedale di Circolo e Fondazione Macchi, Varese, Italy
    An Acad Bras Cienc 79:285-97. 2007
    ..As a result, changes in lung extracellular matrix significantly affect edema formation and distribution in the lung...
  18. ncbi request reprint Functional arrangement of rat diaphragmatic initial lymphatic network
    Annalisa Grimaldi
    Dipartimento di Biologia Strutturale e Funzionale, Universita degli Studi dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    Am J Physiol Heart Circ Physiol 291:H876-85. 2006
    ....
  19. doi request reprint Chondroitin sulfates act as extracellular gating modifiers on voltage-dependent ion channels
    Davide Vigetti
    1Università dell Insubria, Dipartimento di Scienze Biomediche, Sperimentali e Cliniche, Varese, Italy
    Cell Physiol Biochem 22:137-46. 2008
    ..We wanted to test whether chondroitin sulfates at physiological concentration can effectively modulate the gating properties of VOCs...