M Muscaritoli

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. ncbi The "parallel pathway": a novel nutritional and metabolic approach to cancer patients
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza University of Rome, Viale dell Universita, 37, 00185, Rome, Italy
    Intern Emerg Med 6:105-12. 2011
  2. ncbi Nutritional and metabolic support in patients with amyotrophic lateral sclerosis
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza, University of Rome, Rome, Italy
    Nutrition 28:959-66. 2012
  3. ncbi Parenteral nutrition in advanced cancer patients
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza University of Rome, Italy
    Crit Rev Oncol Hematol 84:26-36. 2012
  4. ncbi Prevention and treatment of cancer cachexia: new insights into an old problem
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Viale dell Universita 37, 00185 Rome, Italy
    Eur J Cancer 42:31-41. 2006
  5. ncbi Anorexia in hemodialysis patients: the possible role of des-acyl ghrelin
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Am J Nephrol 27:360-5. 2007
  6. ncbi Malnutrition and wasting in renal disease
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy
    Curr Opin Clin Nutr Metab Care 12:378-83. 2009
  7. ncbi Therapy of muscle wasting in cancer: what is the future?
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Curr Opin Clin Nutr Metab Care 7:459-66. 2004
  8. ncbi Effects of simvastatin administration in an experimental model of cancer cachexia
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Nutrition 19:936-9. 2003
  9. ncbi Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics"
    M Muscaritoli
    Department of Clinical Medicine, La Sapienza, University of Rome, Viale dell Universita, 37, Rome 00185, Italy
    Clin Nutr 29:154-9. 2010
  10. ncbi Nutritional and metabolic support in patients undergoing bone marrow transplantation
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza Rome, Italy
    Am J Clin Nutr 75:183-90. 2002

Collaborators

Detail Information

Publications35

  1. ncbi The "parallel pathway": a novel nutritional and metabolic approach to cancer patients
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza University of Rome, Viale dell Universita, 37, 00185, Rome, Italy
    Intern Emerg Med 6:105-12. 2011
    ..The "parallel pathway" implies a multiprofessional and multimodal approach aimed at ensuring early, appropriate and continuous nutritional and metabolic support to cancer patients in any phase of their cancer journey...
  2. ncbi Nutritional and metabolic support in patients with amyotrophic lateral sclerosis
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza, University of Rome, Rome, Italy
    Nutrition 28:959-66. 2012
    ....
  3. ncbi Parenteral nutrition in advanced cancer patients
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza University of Rome, Italy
    Crit Rev Oncol Hematol 84:26-36. 2012
    ..Decisions regarding treatment initiation and its possible withdrawal should be made based on the best available evidence and non on cultural and personal attitudes...
  4. ncbi Prevention and treatment of cancer cachexia: new insights into an old problem
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Viale dell Universita 37, 00185 Rome, Italy
    Eur J Cancer 42:31-41. 2006
    ..The present review will focus on the potential biochemical and molecular targets of CC therapy, and will define the rationale for a novel, gene therapy-based approach...
  5. ncbi Anorexia in hemodialysis patients: the possible role of des-acyl ghrelin
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Am J Nephrol 27:360-5. 2007
    ..The aim of this cross-sectional study is to clarify whether anorexia and body weight change in HD patients relate to plasma des-acyl ghrelin levels...
  6. ncbi Malnutrition and wasting in renal disease
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy
    Curr Opin Clin Nutr Metab Care 12:378-83. 2009
    ..This review provides an update on the recent advances in the understanding of the mechanisms underlying protein-energy wasting, both in experimental and human models, and on the currently available therapeutic approaches...
  7. ncbi Therapy of muscle wasting in cancer: what is the future?
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Curr Opin Clin Nutr Metab Care 7:459-66. 2004
    ..The aim of the present review is to provide insights into the future therapeutic approaches to cancer-related muscle wasting that flow from the progressive knowledge of mechanisms regulating muscle mass in health and disease...
  8. ncbi Effects of simvastatin administration in an experimental model of cancer cachexia
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Nutrition 19:936-9. 2003
    ..We evaluated whether statins, in view of their anti-inflammatory properties, may effectively prevent the onset or modulate the severity of muscle wasting during cancer cachexia...
  9. ncbi Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics"
    M Muscaritoli
    Department of Clinical Medicine, La Sapienza, University of Rome, Viale dell Universita, 37, Rome 00185, Italy
    Clin Nutr 29:154-9. 2010
    ....
  10. ncbi Nutritional and metabolic support in patients undergoing bone marrow transplantation
    Maurizio Muscaritoli
    Department of Clinical Medicine, University La Sapienza Rome, Italy
    Am J Clin Nutr 75:183-90. 2002
    ....
  11. ncbi Impaired nutritional status in common variable immunodeficiency patients correlates with reduced levels of serum IgA and of circulating CD4+ T lymphocytes
    M Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Eur J Clin Invest 31:544-9. 2001
    ..Infections, persistent diarrhoea and malabsorption may result in malnutrition, which may in turn contribute to increased morbidity. In this paper, the prevalence of malnutrition in CVI was evaluated...
  12. ncbi Effect of cisplatin and paclitaxel on plasma free tryptophan levels. An in vitro study
    M Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Adv Exp Med Biol 467:275-8. 1999
    ..Whether increased TRP availability for 5-HT synthesis might be the pathogenic mechanism for CP-induced DE in vivo, is currently being tested...
  13. ncbi Malnutrition in hemodialysis patients: what therapy?
    Maurizio Bossola
    Istituto di Clinica Chirurgica, Universita Cattolica del Sacro Cuore, Rome, Italy
    Am J Kidney Dis 46:371-86. 2005
    ..Malnutrition still remains a great challenge for nephrologists in the third millennium...
  14. ncbi Reduction of glycosylated hemoglobin with stable insulin levels in a diabetic patient with chronic myeloid leukemia responsive to imatinib
    M Breccia
    Department of Cellular Biotechnology and Hematology, University La Sapienza, Rome, Italy
    Haematologica 90:ECR21. 2005
  15. ncbi Metabolic and clinical effects of the supplementation of a functional mixture of amino acids in cerebral hemorrhage
    Alessandro Laviano
    Department of Clinical Medicine, Sapienza University, Rome, Italy
    Neurocrit Care 14:44-9. 2011
    ..The aim of this study was to test whether such effects could be replicated in an acute clinical model of hypercatabolism...
  16. ncbi New strategies to overcome cancer cachexia: from molecular mechanisms to the 'Parallel Pathway'
    Maurizio Muscaritoli
    Department of Clinical Medicine, Sapienza University of Rome Viale dell Universita, 37 00185 Rome, Italy
    Asia Pac J Clin Nutr 17:387-90. 2008
    ....
  17. ncbi Antimyopathic effects of carnitine and nicotine
    Alessandro Laviano
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Curr Opin Clin Nutr Metab Care 9:442-8. 2006
    ..This anorexia/cachexia syndrome leads to deterioration of quality of life, and increased morbidity and mortality. The clinical efficacy of currently available therapeutic strategies is limited and more effective treatments are needed...
  18. ncbi Therapy insight: Cancer anorexia-cachexia syndrome--when all you can eat is yourself
    Alessandro Laviano
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Nat Clin Pract Oncol 2:158-65. 2005
    ....
  19. ncbi Branched-chain amino acids: the best compromise to achieve anabolism?
    Alessandro Laviano
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Curr Opin Clin Nutr Metab Care 8:408-14. 2005
    ..More effective therapies are needed to promote appetite and food intake, to preserve lean body mass, and to ameliorate patients' psychological distress...
  20. ncbi Tumor-induced changes in host metabolism: a possible role for free tryptophan as a marker of neoplastic disease
    Alessandro Laviano
    Department of Clinical Medicine, University of Rome La Sapienza, Rome, Italy
    Adv Exp Med Biol 527:363-6. 2003
    ..High plasma free tryptophan concentrations seem to be directly related to the presence of the tumor, since in breast cancer patients they returned to within normal range after eradicative surgery...
  21. ncbi Serum tumour necrosis factor-alpha levels in cancer patients are discontinuous and correlate with weight loss
    M Bossola
    Universita Cattolica del Sacro Cuore, Rome, Italy
    Eur J Clin Invest 30:1107-12. 2000
    ..Tumour necrosis factor-alpha (TNF) has been regarded as a potential mediator of cancer cachexia. Assessment of TNF circulating levels in cancer patients and their correlation with weight loss has led to controversial results...
  22. ncbi Plasma amino acid concentrations in patients with acute myelogenous leukemia
    M Muscaritoli
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Nutrition 15:195-9. 1999
    ..Further studies are under way aimed at clarifying whether PFAA might predict prognosis in AML, whether PFAA is normalized by remission induction, and if its correction may be of any benefit for patients with hematologic malignancies...
  23. ncbi Switch from bicarbonate hemodialysis to hemodiafiltration with online regeneration of the ultrafiltrate (HFR): effects on nutritional status, microinflammation, and beta-microglobulin
    Maurizio Bossola
    Istituto di Clinica Chirurgica, Universita Cattolica del Sacro Cuore, Rome, Italy
    Artif Organs 29:259-63. 2005
    ..The purpose of the present prospective study was to ascertain whether HRF improves the nutritional status, reduces microinflammation, and decreases serum beta2-microglobulin levels in patients with end-stage renal disease (ESRD)...
  24. ncbi Variables associated with reduced dietary intake in hemodialysis patients
    Maurizio Bossola
    Istituto di Clinica Chirurgica, Universita Cattolica del Sacro Cuore di Roma, Rome, Italy
    J Ren Nutr 15:244-52. 2005
    ....
  25. ncbi Free tryptophan/large neutral amino acids ratios in blood plasma do not predict cerebral spinal fluid tryptophan concentrations in interleukin-1-induced anorexia
    Alessio Molfino
    Department of Clinical Medicine, Sapienza University of Rome, 00185 Rome, Italy
    Pharmacol Biochem Behav 89:31-5. 2008
    ..Considering the possible role of the raised CSF TRP in influencing brain serotonin activity, it is postulated that increased serotonergic neurotransmission could be involved in IL-1 induced anorexia...
  26. ncbi Muscle ubiquitin m-rNA levels in patients with end-stage renal disease on maintenance hemodialysis
    Maurizio Bossola
    Institute of Clinical Surgery, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Nephrol 15:552-7. 2002
    ..The present study was designed to investigate the expression of ubiquitin mRNAs in skeletal muscle of patients with ESRD on maintenance HD...
  27. ncbi Idiopathic AL amyloidosis and biclonal paraproteinemia: a case report and review of the literature
    F Pace
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Amyloid 8:215-9. 2001
    ..Further studies, however, are necessary to clarify the true incidence and the clinical features of idopathic AL amyloidosis associated with biclonal gammopathy...
  28. ncbi Anorexia and serum leptin levels in hemodialysis patients
    Maurizio Bossola
    Istituto di Clinica Chirurgica, , Roma, Italia
    Nephron Clin Pract 97:c76-82. 2004
    ..CONCLUSION: The present results indicate that mechanisms other than increases in serum leptin levels might be involved in the pathogenesis of HD-related anorexia...
  29. ncbi Phase II study of high-dose fish oil capsules for patients with cancer-related cachexia: a Cancer and Leukemia Group B study
    Alessandro Laviano
    Cancer 103:651-2. 2005
  30. ncbi IGF-1 is downregulated in experimental cancer cachexia
    Paola Costelli
    Dipartimento di Medicina e Oncologia Sperimentale, Universita di Torino, Turin, Italy
    Am J Physiol Regul Integr Comp Physiol 291:R674-83. 2006
    ..Moreover, no simple relation linking IGF-1 and/or atrogin-1 mRNA levels and muscle atrophy could be observed in these experimental conditions. Further studies are thus needed to clarify both issues...
  31. ncbi Increased muscle proteasome activity correlates with disease severity in gastric cancer patients
    Maurizio Bossola
    Istituto di Clinica Chirurgica, Universita Cattolica del Sacro Cuore, Roma, Italy
    Ann Surg 237:384-9. 2003
    ..To investigate the state of activation of the ATP-ubiquitin-dependent proteolytic system in the skeletal muscle of gastric cancer patients...
  32. ncbi Does leptin contribute to uraemic cachexia?
    Maurizio Bossola
    Nephrol Dial Transplant 21:1125-6; author reply 1126. 2006
  33. ncbi Skeletal muscle apoptosis is not increased in gastric cancer patients with mild-moderate weight loss
    Maurizio Bossola
    Istituto di Clinica Chirurgica, Università Cattolica del Sacro Cuore Largo A Gemelli, 8, 00168 Rome, Italy
    Int J Biochem Cell Biol 38:1561-70. 2006
    ....
  34. ncbi Statins, coenzyme Q10, and cachexia: what's the link?
    Alessio Molfino
    Am J Cardiol 100:1497-8. 2007
  35. ncbi Is des-acyl ghrelin contributing to uremic anorexia?
    Alessio Molfino
    Am J Clin Nutr 86:1550-1; author reply 1551-3. 2007