Carla Mucignat


Affiliation: University of Padova
Country: Italy


  1. Del Vecchio C, Calistri A, Parolin C, Mucignat Caretta C. Lentiviral Vectors as Tools for the Study and Treatment of Glioblastoma. Cancers (Basel). 2019;11: pubmed publisher
    ..Finally, LV allow the setting up of improved animal models crucial for the validation of GBM specific therapies. ..
  2. Ricatti J, Acquasaliente L, Ribaudo G, De Filippis V, Bellini M, Llovera R, et al. Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity. Sci Rep. 2019;9:300 pubmed publisher
    ..A single amino acid substitution in the binding pocket can dramatically change the MUPs binding affinity and ligand specificity. These results have great potential for the design of new biosensor and gas-sensor recognition elements. ..
  3. Mucignat Caretta C, Denaro L, Redaelli M, D Avella D, Caretta A. Protein kinase A regulatory subunit distribution in medulloblastoma. BMC Cancer. 2010;10:141 pubmed publisher
    ..Fluorescent cAMP labelling was observed only in medulloblastoma. A different distribution of cAMP dependent protein kinases has been observed in medulloblastoma. ..
  4. Mucignat Caretta C, Caretta A. Aggregates of cAMP-dependent kinase isoforms characterize different areas in the developing central nervous system of the chicken, Gallus gallus. Dev Neurosci. 2011;33:144-58 pubmed publisher
  5. Mucignat C, Caretta A. Drug-induced Parkinson's disease modulates protein kinase A and Olfactory Marker Protein in the mouse olfactory bulb. Behav Brain Funct. 2017;13:1 pubmed publisher
    ..MPTP mice do not present behavioural deficits in olfactory search, yet immunoreactivity reveals modifications in the olfactory bulb, and suggests changes in intracellular signal processing, possibly linked to neuron survival after MPTP. ..
  6. Mucignat Caretta C, Denaro L, D Avella D, Caretta A. Protein Kinase A Distribution Differentiates Human Glioblastoma from Brain Tissue. Cancers (Basel). 2017;10: pubmed publisher
    ..These data raise the possibility of targeting the PKA intracellular pathway for the development of diagnostic and/or therapeutic tools for human glioblastoma. ..
  7. Mucignat Caretta C, Bondi M, Rubini A, Calabrese F, Barbato A. The olfactory system is affected by steroid aerosol treatment in mice. Am J Physiol Lung Cell Mol Physiol. 2009;297:L1073-81 pubmed publisher
  8. Mucignat Caretta C. The rodent accessory olfactory system. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2010;196:767-77 pubmed publisher
    ..Different brain areas receive inputs from both the main and the accessory olfactory systems, possibly merging the stimulation of the two sensory organs to originate a more complex and integrated chemosensory perception. ..
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    Mucignat Caretta C, Caretta A. Clustered distribution of cAMP-dependent protein kinase regulatory isoform RI alpha during the development of the rat brain. J Comp Neurol. 2002;451:324-33 pubmed
    ..During the rat's lifespan, the distribution of these peculiar RI alpha clusters undergo changes that may contribute to shape neuronal responses differentially to agents modifying cAMP levels. ..

More Information


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    Mucignat Caretta C, Caretta A. Localization of Triton-insoluble cAMP-dependent kinase type RIbeta in rat and mouse brain. J Neurocytol. 2001;30:885-94 pubmed
    ..It is suggested that, as is the case for structural proteins, a different supramolecular organization of similar regulatory proteins may be crucial in order to fulfill different functions. ..
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    Mucignat Caretta C, Caretta A. Regional variations in the localization of insoluble kinase A regulatory isoforms during rodent brain development. J Chem Neuroanat. 2004;27:201-12 pubmed