Affiliation: University of Milan
- MicroRNAs are associated with blood-pressure effects of exposure to particulate matter: Results from a mediated moderation analysisValeria Motta
EPIGET Epidemiology, Epigenetics and Toxicology Lab Department of Clinical Sciences and Community Health, Universita degli Studi di Milano, 20122 Milan, Italy Electronic address
Environ Res 146:274-81. 2016..To elucidate the mechanisms underlying this relationship, we investigated whether the effects of particulate matter of less than 10μm in aerodynamic diameter (PM10) on BP are mediated by microRNAs...
- Susceptibility to particle health effects, miRNA and exosomes: rationale and study protocol of the SPHERE studyValentina Bollati
Molecular Epidemiology and Environmental Epigenetics Laboratory, Department of Clinical Sciences and Community Health, Universita degli Studi di Milano, Milan, Italy
BMC Public Health 14:1137. 2014..The SPHERE ("Susceptibility to Particle Health Effects, miRNAs and Exosomes") project was granted by ERC-2011-StG 282413, to examine possible molecular mechanisms underlying the effects of PM exposure in relation to health outcomes...
- Integrative Analysis of miRNA and inflammatory gene expression after acute particulate matter exposureValeria Motta
Exposure, Epidemiology and Risk Program, Department of Environmental Health, Laboratory of Environmental Epigenetics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Toxicol Sci 132:307-16. 2013..Acute PM exposure may affect gene regulation through PM-responsive miRNAs that directly or indirectly control inflammatory gene expression...
- Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutantsHyang Min Byun
Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA, USA
Part Fibre Toxicol 10:28. 2013..The purpose of the study is to evaluate sensitivity of DNA methylation in differentially‒evolved LINE, Alu, and HERV subfamilies to different types of airborne pollutants...
- Effects of short-term exposure to inhalable particulate matter on DNA methylation of tandem repeatsLiqiong Guo
Laboratory of Environmental Epigenetics, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts Key Laboratory of Pollution Processes and Environmental Criteria Ministry of Education, College of Environmental Sciences and Engineering, Nankai University, Tianjin, China
Environ Mol Mutagen 55:322-35. 2014..Measuring tandem-repeat hypomethylation in easy-to-obtain blood specimens might identify individuals with biological effects and potential cancer risk from PM exposure...
- Predicting DNA methylation level across human tissuesBaoshan Ma
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA, College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning Province 116026, China, Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK, Department of Clinical Sciences and Community, University of Milan, Milan 20122, Italy, Division of Cardiac Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA and Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
Nucleic Acids Res 42:3515-28. 2014..g. blood) could be recalibrated to improve understanding of epigenetics in hard-to-access tissues (e.g. atrium) and might enable non-invasive disease screening using epigenetic profiles. ..
- Effects of airborne pollutants on mitochondrial DNA methylationHyang Min Byun
Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA 02115, USA
Part Fibre Toxicol 10:18. 2013..However, no study has yet investigated whether mitochondrial DNA methylation is sensitive to pro-oxidant environmental exposures...