Marta Mosca

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. ncbi request reprint [Chronic inflammation and endothelial dysfunction: analysis of a cohort of patients with SLE and UCTD]
    C Tani
    UO Reumatologia, Dipartimento di Medicina Interna, Universita di Pisa, Italia
    Reumatismo 58:212-8. 2006
  2. ncbi request reprint Pregnant patient with dermatomyositis successfully treated with intravenous immunoglobulin therapy
    M Mosca
    University of Pisa, Pisa, Italy
    Arthritis Rheum 53:119-21. 2005
  3. pmc European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies
    M Mosca
    Correspondence to Dr Marta Mosca, University of Pisa, Via Roma 67, Ospedale S Chiara, Pisa, 56126, Italy
    Ann Rheum Dis 69:1269-74. 2010
  4. ncbi request reprint Prevalence and clinico-serological correlations of anti-alpha-enolase, anti-C1q, and anti-dsDNA antibodies in patients with systemic lupus erythematosus
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    J Rheumatol 33:695-7. 2006
  5. doi request reprint Cell-free DNA in the plasma of patients with systemic sclerosis
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Via Roma no 67, 56126 Pisa, Italy
    Clin Rheumatol 28:1437-40. 2009
  6. ncbi request reprint Assessing remission in systemic lupus erythematosus
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 24:S-99-104. 2006
  7. ncbi request reprint LJP-394 (abetimus sodium) in the treatment of systemic lupus erythematosus
    Marta Mosca
    University of Pisa, Rheumatology Unit, Department of Internal Medicine, Via Roma, 6756126 Pisa, Italy
    Expert Opin Pharmacother 8:873-9. 2007
  8. ncbi request reprint Anti-C1q antibodies in pregnant patients with systemic lupus erythematosus
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 25:449-52. 2007
  9. doi request reprint Occurrence of organ-specific and systemic autoimmune diseases among the first- and second-degree relatives of Caucasian patients with connective tissue diseases: report of data obtained through direct patient interviews
    Marta Mosca
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy
    Clin Rheumatol 27:1045-8. 2008
  10. ncbi request reprint Disease-specific quality indicators, guidelines, and outcome measures in systemic lupus erythematosus (SLE)
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 25:107-13. 2007

Detail Information

Publications57

  1. ncbi request reprint [Chronic inflammation and endothelial dysfunction: analysis of a cohort of patients with SLE and UCTD]
    C Tani
    UO Reumatologia, Dipartimento di Medicina Interna, Universita di Pisa, Italia
    Reumatismo 58:212-8. 2006
    ....
  2. ncbi request reprint Pregnant patient with dermatomyositis successfully treated with intravenous immunoglobulin therapy
    M Mosca
    University of Pisa, Pisa, Italy
    Arthritis Rheum 53:119-21. 2005
  3. pmc European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies
    M Mosca
    Correspondence to Dr Marta Mosca, University of Pisa, Via Roma 67, Ospedale S Chiara, Pisa, 56126, Italy
    Ann Rheum Dis 69:1269-74. 2010
    ..To develop recommendations for monitoring patients with systemic lupus erythematosus (SLE) in clinical practice and observational studies and to develop a standardised core set of variables to monitor SLE...
  4. ncbi request reprint Prevalence and clinico-serological correlations of anti-alpha-enolase, anti-C1q, and anti-dsDNA antibodies in patients with systemic lupus erythematosus
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    J Rheumatol 33:695-7. 2006
    ..To evaluate the prevalence and clinico-serological correlations of anti-enolase, anti-C1q, and anti-dsDNA antibodies in patients with systemic lupus erythematosus (SLE)...
  5. doi request reprint Cell-free DNA in the plasma of patients with systemic sclerosis
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Via Roma no 67, 56126 Pisa, Italy
    Clin Rheumatol 28:1437-40. 2009
    ..05). Our data suggest that cf-DNA could provide a useful biomarker for the assessment of disease activity in SSc patients...
  6. ncbi request reprint Assessing remission in systemic lupus erythematosus
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 24:S-99-104. 2006
    ..Defining remission in SLE in an objective manner depends on reaching agreement on the relative importance of systemic activity, damage, QoL, and laboratory tests, as well as activity and damage of specific organs...
  7. ncbi request reprint LJP-394 (abetimus sodium) in the treatment of systemic lupus erythematosus
    Marta Mosca
    University of Pisa, Rheumatology Unit, Department of Internal Medicine, Via Roma, 6756126 Pisa, Italy
    Expert Opin Pharmacother 8:873-9. 2007
    ..This paper reviews the principal aspects of chemistry, pharmacokinetics, efficacy and safety of LJP-394, and analyses studies on animal models and clinical studies conducted in the last few years...
  8. ncbi request reprint Anti-C1q antibodies in pregnant patients with systemic lupus erythematosus
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 25:449-52. 2007
    ..To study anti-C1q antibodies in pregnant patients with systemic lupus erythematosus (SLE) and to evaluate their prognostic significance for the occurrence of disease flares or pregnancy complications...
  9. doi request reprint Occurrence of organ-specific and systemic autoimmune diseases among the first- and second-degree relatives of Caucasian patients with connective tissue diseases: report of data obtained through direct patient interviews
    Marta Mosca
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy
    Clin Rheumatol 27:1045-8. 2008
    ..5%). In conclusion, these data confirm the high prevalence of autoimmune conditions, particularly of AT disease, among the relatives of patients...
  10. ncbi request reprint Disease-specific quality indicators, guidelines, and outcome measures in systemic lupus erythematosus (SLE)
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 25:107-13. 2007
    ..Certainly much progress will be made in the near future. A practical, user-friendly tool for physicians that will help them deliver high quality care to populations is also needed...
  11. ncbi request reprint Undifferentiated connective tissue diseases (UCTD): a new frontier for rheumatology
    Marta Mosca
    Rheumatology Unit, University of Pisa, Italy
    Best Pract Res Clin Rheumatol 21:1011-23. 2007
    ..However, such identification is of paramount importance, and further analysis is necessary to improve the sensitivity and specificity of the proposed classification criteria...
  12. doi request reprint Defining undifferentiated connective tissue diseases: a challenge for rheumatologists
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Lupus 17:278-80. 2008
  13. doi request reprint A case of undifferentiated connective tissue disease: is it a distinct clinical entity?
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Nat Clin Pract Rheumatol 4:328-32. 2008
    ..In November 2001, a 24-year-old woman with thrombocytopenia and Raynaud's phenomenon presented to our clinic. Her physical examination was unremarkable except for bruising on her legs and arms...
  14. doi request reprint Undifferentiated connective tissue diseases (UCTD): simplified systemic autoimmune diseases
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Autoimmun Rev 10:256-8. 2011
    ..Classification criteria for stable UCTDs are still matter of debate...
  15. ncbi request reprint [Analysis of the evolution to defined connective tissue diseases of patients with "early unidifferentiated connective tissue diseases (UCTD)"]
    M Mosca
    U O di Reumatologia, Dipartimento di Medicina Interna, Universita degli Studi di Pisa, Italia
    Reumatismo 60:35-40. 2008
    ..The early identification of stable UCTD is very important both from a clinical and a research point of view. Future research is needed to define a new set of classification criteria...
  16. ncbi request reprint Undifferentiated connective tissue diseases in 2004
    M Mosca
    Department of Internal Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 22:S14-8. 2004
    ..Before they can be so used, more must be discovered about their nature and characteristics, and studies will be necessary to improve the sensitivity and specificity of the existing preliminary classification criteria...
  17. doi request reprint Development of quality indicators to evaluate the monitoring of SLE patients in routine clinical practice
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Autoimmun Rev 10:383-8. 2011
    ..A disease specific set of quality assessment tools should help physicians deliver high quality of care across populations. Routine updates will be needed...
  18. doi request reprint The development of a simple questionnaire to screen patients with SLE for the presence of neuropsychiatric symptoms in routine clinical practice
    M Mosca
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Lupus 20:485-92. 2011
    ..The creation of a physician-administered questionnaire to screen patients with Systemic Lupus Erythematosus (SLE) for the presence of symptoms suggestive of neuropsychiatric involvement (NPSLE)...
  19. ncbi request reprint Alteration of microcirculation is a hallmark of very early systemic sclerosis patients: a laser speckle contrast analysis
    Alessandra Della Rossa
    Department of Musculoskeletal and Skin Diseases, Rheumatology Unit, University of Pisa, Italy
    Clin Exp Rheumatol 31:109-14. 2013
    ..To investigate blood flow and microvascular reactivity by laser speckle perfusion imager (Perimed, Jarfalla) in consecutive patients affected by Raynaud's phenomenon at baseline and following dynamic stimulations...
  20. ncbi request reprint Undifferentiated connective tissue disease: analysis of 83 patients with a minimum followup of 5 years
    Marta Mosca
    Clinical Immunology Unit and Rheumatology Unit, University of Pisa, Pisa, Italy
    J Rheumatol 29:2345-9. 2002
    ..Previously, we had described a series of 91 patients with UCTD who were followed at our unit for a minimum period of one year; here we report the extended followup of these patients...
  21. ncbi request reprint Overlap of ACA-positive systemic sclerosis and Sjögren's syndrome: a distinct clinical entity with mild organ involvement but at high risk of lymphoma
    Chiara Baldini
    University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 31:272-80. 2013
    ....
  22. ncbi request reprint A systematic literature review of the economic impact of ankylosing spondylitis
    Ilaria Palla
    Istituto di Management, Scuola Superiore Sant Anna, Pisa, Italy
    Clin Exp Rheumatol 30:S136-41. 2012
    ..Therefore indirect costs may become very high in case of private insurance regimes because of their more detailed identification...
  23. ncbi request reprint The economic impact of gout: a systematic literature review
    Leopoldo Trieste
    Istituto di Management, Scuola Superiore Sant Anna, Pisa, Italy
    Clin Exp Rheumatol 30:S145-8. 2012
    ....
  24. ncbi request reprint Systemic vasculitis: how little we know about their societal and economic burden
    Leopoldo Trieste
    Istituto di Management, Scuola Superiore Sant Anna, Pisa, Italy
    Clin Exp Rheumatol 30:S154-6. 2012
    ..Policy makers, private and public organisations involved in the care of VAs need data to programme future investment or make cost-effectiveness analysis for introducing new drugs or protocols...
  25. doi request reprint Prevalence of thyroid dysfunctions in systemic lupus erythematosus
    Alessandro Antonelli
    Metabolism Unit Department of Internal Medicine, University of Pisa, 56100 Pisa, Italy
    Metabolism 59:896-900. 2010
    ..Subjects at high risk (women, positive AbTPOs, hypoechoic, and small thyroid) should have thyroid function follow-up and appropriate treatment in due course...
  26. ncbi request reprint Saliva as an ideal milieu for emerging diagnostic approaches in primary Sjögren's syndrome
    Chiara Baldini
    University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 30:785-90. 2012
    ....
  27. doi request reprint Vascular reactivity in patients with undifferentiated connective tissue diseases
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Atherosclerosis 203:185-91. 2009
    ..We investigated endothelial function in the peripheral circulation of patients with undifferentiated connective tissue diseases (UCTDs), in comparison to healthy controls...
  28. doi request reprint Thyroid cancer in systemic lupus erythematosus: a case-control study
    Alessandro Antonelli
    Departmentof Internal Medicine, University of Pisa, I 56100 Pisa, Italy
    J Clin Endocrinol Metab 95:314-8. 2010
    ..Although advances in treatment have permitted patients with systemic lupus erythematosus (SLE) to live longer, the rates of several types of cancers in these patients appear to be increasing...
  29. doi request reprint Cancer-associated myositis: a 35-year retrospective study of a monocentric cohort
    Rossella Neri
    Rheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Via Roma 67, 56126, Pisa, Italy
    Rheumatol Int 34:565-9. 2014
    ..In conclusion, the association of male sex, older age, DM, dysphagia at onset, lower CK, and autoantibodies negativity carries a high suspicion of CAM. ..
  30. doi request reprint Undifferentiated CTD: a wide spectrum of autoimmune diseases
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Best Pract Res Clin Rheumatol 26:73-7. 2012
    ..In the present article, the literature data on undifferentiated diseases and their clinical spectrum as well as the importance of the definition of new classificative criteria are discussed...
  31. ncbi request reprint Minor salivary gland biopsy and Sjögren's syndrome: comparative analysis of biopsies among different Italian rheumatologic centers
    Antonio Gaetano Tavoni
    Clinical Immunology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 30:929-33. 2012
    ....
  32. ncbi request reprint New drugs in systemic lupus erythematosus: when to start and when to stop
    Marta Mosca
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 31:S82-5. 2013
    ..In this article, we review indications for the use of new drugs in SLE, and examine existing data on patient outcome after withdrawal, focusing our attention on rituximab and belimumab. ..
  33. doi request reprint Integrated backscatter analysis of carotid intima-media complex in patients with systemic lupus erythematosus
    Marco Rossi
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Rheumatol 27:1485-8. 2008
    ..Further studies are needed to clearly demonstrate that early carotid sclerosis affects hypertensive SLE patients...
  34. ncbi request reprint Clinical and methodological aspects of endothelial function in patients with systemic autoimmune diseases
    L Ghiadoni
    Hypertension Unit, Department of Internal Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 26:680-7. 2008
    ..No single test currently available is specific for the vascular district tested or the risk factor/diseases considered, and a panel of several tests is therefore needed to characterize the multiple aspects of endothelial biology...
  35. ncbi request reprint Genetics of drug response to immunosuppressive treatment and prospects for personalized therapy
    R Danesi
    Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, 55 Via Roma, 56126 Pisa, Italy
    Mol Med Today 6:475-82. 2000
    ....
  36. ncbi request reprint Risk factors for osteoporosis in female patients with systemic lupus erythematosus
    O Di Munno
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Lupus 13:724-30. 2004
    ..Therefore the potential risks and lack of efficacy data on fracture risk reduction in premenopausal patients must be weighed against their proven efficacy in postmenopausal patients...
  37. doi request reprint Risk factors for pregnancy failure in patients with anti-phospholipid syndrome treated with conventional therapies: a multicentre, case-control study
    Amelia Ruffatti
    Department of Clinical and Experimental Medicine, Rheumatology Unit, University of Padua, Padua, Italy
    Rheumatology (Oxford) 50:1684-9. 2011
    ..To identify the risk factors associated with pregnancy failure in patients with APS treated with conventional therapy...
  38. ncbi request reprint Undifferentiated connective tissue diseases (UCTD)
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Via Roma, 67, 56126 Pisa, Italy
    Autoimmun Rev 6:1-4. 2006
    ..Stable UCTD are considered as distinct clinical entities and therefore it has been proposed to define those conditions as UCTD. Classificative criteria have also been proposed and a work to better define them is still under way...
  39. ncbi request reprint Withdrawal of therapy in non-renal systemic lupus erythematosus: is this an achievable goal?
    Marta Mosca
    Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 31:S71-4. 2013
    ....
  40. ncbi request reprint The rationale of pharmacoeconomic analysis in rheumatologic indications
    Giuseppe Turchetti
    Istituto di Management, Scuola Superiore Sant Anna, Pisa, Italy
    Clin Exp Rheumatol 30:S64-71. 2012
    ....
  41. ncbi request reprint Treat-to-target in systemic lupus erythematosus: where are we today?
    Marta Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 30:S112-5. 2012
    ..In the present paper, observations raised at the meeting and literature data on potential therapeutic targets are reported. The working group on T2T/SLE will continue work over the coming year...
  42. doi request reprint Cerebral blood flow in depressed patients with systemic lupus erythematosus
    Giampiero Giovacchini
    Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy
    J Rheumatol 37:1844-51. 2010
    ..To characterize the neural circuitry involved in depression associated with systemic lupus erythematosus (SLE), we used single photon emission computed tomography (SPECT) to study regional cerebral blood flow (CBF) in patients with SLE...
  43. ncbi request reprint Renal flares in 91 SLE patients with diffuse proliferative glomerulonephritis
    Marta Mosca
    Rheumatology Unit, University of Pisa, Pisa, Italy
    Kidney Int 61:1502-9. 2002
    ..The aim of this retrospective study was to evaluate the incidence and prognostic significance of renal flares in SLE patients with DPGN and to identify predictors for the occurrence of flares...
  44. ncbi request reprint The validity of the ECLAM index for the retrospective evaluation of disease activity in systemic lupus erythematosus
    M Mosca
    Department of Internal Medicine, University of Pisa, Italy
    Lupus 9:445-50. 2000
    ..To determine whether the European Consensus Lupus Activity Measurement Index (ECLAM) can be used to evaluate disease activity in patients retrospectively from the data provided in their clinical charts...
  45. pmc Correlations of Y chromosome microchimerism with disease activity in patients with SLE: analysis of preliminary data
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Ann Rheum Dis 62:651-4. 2003
    ..Recently it has been suggested that microchimerism may have a significant role in the aetiopathogenesis of some autoimmune diseases...
  46. ncbi request reprint Pregnancy outcome in patients with undifferentiated connective tissue disease: a preliminary study on 25 pregnancies
    M Mosca
    Department of Internal Medicine, University of Pisa, Italy
    Lupus 11:304-7. 2002
    ..Further prospective studies will be necessary to confirm these preliminary observations...
  47. pmc Systemic lupus erythematosus and the economic perspective: a systematic literature review and points to consider
    Giuseppe Turchetti
    Istituto di Management, Scuola Superiore Sant Anna, Pisa, Italy
    Clin Exp Rheumatol 30:S116-22. 2012
    ..Future treat-to-target strategies will likely include evaluation of their pharmacoeconomic implications...
  48. ncbi request reprint Genetic polymorphisms of thiopurine S-methyltransferase in a cohort of patients with systemic autoimmune diseases
    C Tani
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Exp Rheumatol 27:321-4. 2009
    ....
  49. ncbi request reprint Therapy with pulse methylprednisolone and short course pulse cyclophosphamide for diffuse proliferative glomerulonephritis
    M Mosca
    Clinical Immunology Unit, University of Pisa, Pisa, Italy
    Lupus 10:253-7. 2001
    ..However, short term IS therapy might not be sufficient to maintain disease control in younger patients with active lesions on renal histology. Such patients might be candidates to receive more prolonged IS treatment...
  50. ncbi request reprint Functional and isokinetic assessment of muscle strength in patients with idiopathic inflammatory myopathies
    R Neri
    University of Pisa, Rheumatology Unit, Department of Internal Medicine, Italy
    Autoimmunity 39:255-9. 2006
    ..To assess muscle strength in patients with idiopathic inflammatory myopathies (IIM) using neuromuscular scales and isokinetic testing...
  51. ncbi request reprint Undifferentiated connective tissue diseases (UCTD): a review of the literature and a proposal for preliminary classification criteria
    M Mosca
    Department of Internal Medicine, University of Pisa, Italy
    Clin Exp Rheumatol 17:615-20. 1999
    ....
  52. ncbi request reprint The value of outcome measures in autoimmune rheumatic diseases
    M Mosca
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy
    Autoimmun Rev 3:S56-7. 2004
  53. ncbi request reprint Treatment of the idiopathic inflammatory myopathies: a retrospective analysis of 63 Caucasian patients longitudinally followed at a single center
    M Mosca
    Clinical Immunology Unit, University of Pisa, Italy
    Clin Exp Rheumatol 18:451-6. 2000
    ..To analyze the therapies used over the past 20 years at a single center to treat patients with idiopathic inflammatory myopathies (IIM), and to compare their effectiveness...
  54. ncbi request reprint Assessment of patients with systemic lupus erythematosus and the use of lupus disease activity indices
    Bridget Griffiths
    Freeman Hospital, Newcastle upon Tyne, UK
    Best Pract Res Clin Rheumatol 19:685-708. 2005
    ..In addition to the assessment of disease activity, the evaluation of damage using the validated SLICC/ACR damage index and health-related quality of life is advised for clinical research...
  55. ncbi request reprint Defining unclassifiable connective tissue diseases: incomplete, undifferentiated, or both?
    Andrea Doria
    J Rheumatol 32:213-5. 2005
  56. ncbi request reprint Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients
    Ricard Cervera
    Institut Clínic d Infeccions i Immunologia ICII, Hospital Clinic, and Institut d Investigacions Biomè diques August Pi i Sunyer IDIBAPS, Barcelona, Catalonia, Spain
    Arthritis Rheum 46:1019-27. 2002
    ..To analyze the clinical and immunologic manifestations of antiphospholipid syndrome (APS) in a large cohort of patients and to define patterns of disease expression...
  57. ncbi request reprint A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four years
    Gabriella Moroni
    Division of Nephrology, IRCCS Ospedale Maggiore, Via Commenda 15, 20122 Milano, Italy
    Clin J Am Soc Nephrol 1:925-32. 2006
    ..For patients with diffuse proliferative lupus nephritis, azathioprine or cyclosporine combined with corticosteroids demonstrated equal efficacy in the prevention of flares...