Research Topics
Genomes and GenesSpecies | Francesca MoriSummaryAffiliation: University of Florence Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case seriesAndrea Taddio
Institute for Maternal and Child Health IRCCS Burlo Garofolo Trieste and University of Trieste, Via dell Istria 65 1, 34100, Trieste, Italy
Pediatr Rheumatol Online J 9:34. 2011..The documented response to topical tacrolimus eyedrop of uveitis and VKC is also of interest, in particular since to our knowledge there are no published reports on its clinical use in uveitis...
Osteoprotegerin serum levels in Kawasaki disease: an additional potential marker in predicting children with coronary artery involvementGabriele Simonini
Department of Paediatrics, Rheumatology Unit, University of Florence, Florence, Italy
J Rheumatol 32:2233-8. 2005..We evaluated serum levels of OPG in a group of children with Kawasaki disease (KD), before immunoglobulin (IVIG) infusion and at 3-month followup...
Loss of efficacy during long-term infliximab therapy for sight-threatening childhood uveitisG Simonini
Department of Paediatrics, Rheumatology Unit, Anna Meyer Children s Hospital and University of Florence, Italy
Rheumatology (Oxford) 47:1510-4. 2008..To describe efficacy and safety of infliximab in the treatment of childhood chronic uveitis during a long-term follow-up...
Lack of association between the HLA-DRB1 locus and post-streptococcal reactive arthritis and acute rheumatic fever in Italian childrenGabriele Simonini
Rheumatology Unit, Department of Pediatrics, University of Florence, 50132 Firenze, Italy
Semin Arthritis Rheum 34:553-8. 2004..Possible associations with HLA class II antigens of PSReA (DRB1*01) and ARF (DRB1*16) were described previously in white Americans. To confirm these findings, we studied DRB1 alleles in a group of Italian children with PSReA and ARF...
Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patientsGabriele Simonini
Rheumatology Unit, Department of Pediatrics, University of Florence, Via Pico della Mirandola 24, 50132 Florence, Italy
Rheumatol Int 25:336-40. 2005..In 20 subjects requiring local steroid injection, NEP was measured in synovial fluid...
Bone status over 1 yr of etanercept treatment in juvenile idiopathic arthritisG Simonini
Department of Pediatrics Rheumatology Unit, Via Pico della Mirandola 24, 50132 Florence, Italy
Rheumatology (Oxford) 44:777-80. 2005..To evaluate bone mineral status over 1 yr of etanercept treatment in juvenile idiopathic arthritis (JIA)...
Prevention of flare recurrences in childhood-refractory chronic uveitis: an open-label comparative study of adalimumab versus infliximabGabriele Simonini
Rheumatology Unit, Anna Meyer Children s Hospital and Department of Paediatrics, University of Florence, Florence, Italy
Arthritis Care Res (Hoboken) 63:612-8. 2011..To compare the efficacy and safety of adalimumab versus infliximab in an open-label prospective, comparative, multicenter cohort study of childhood noninfectious chronic uveitis...
Macrophage migration inhibitory factor -173 polymorphism and risk of coronary alterations in children with Kawasaki diseaseG Simonini
Department of Paediatrics, Rheumatology Unit, A Meyer Children s Hospital, Florence, Italy
Clin Exp Rheumatol 27:1026-30. 2009..To investigate the possible relationship between MIF -173 polymorphism and susceptibility to, and severity of, Kawasaki disease (KD) in a cohort of Italian patients...
Current therapeutic approaches to autoimmune chronic uveitis in childrenGabriele Simonini
Department of Paediatrics, Anna Meyer Children s Hospital, University of Florence, Italy
Autoimmun Rev 9:674-83. 2010..The aim of this review is to report currently available medical strategies for treatment of childhood sight-threatening chronic uveitis; in addition, a step-by-step approach to the use of immunosuppressants in this context is suggested...
Osteoprotegerin (OPG)/RANK-L system in juvenile idiopathic arthritis: is there a potential modulating role for OPG/RANK-L in bone injury?Laura Masi
Department of Internal Medicine, University of Florence, Florence, Italy
J Rheumatol 31:986-91. 2004....
Serum osteopontin as a predictive marker of responsiveness to methotrexate in juvenile idiopathic arthritisLaura Masi
A Meyer Children s Hospital, University of Florence, Firenze, Italy
J Rheumatol 36:2308-13. 2009..To evaluate if serum concentrations of osteopontin (OPN) at baseline in patients with juvenile idiopathic arthritis (JIA) represent a potential predictor of responsiveness to methotrexate (MTX)...
Defective FOXP3 expression in patients with acute Kawasaki disease and restoration by intravenous immunoglobulin therapyBiagio Olivito
Department of Paediatrics, University of Florence and Anna Meyer Children s Hospital, Florence, Italy
Clin Exp Rheumatol 28:93-7. 2010....
Bone status evaluation with calcaneal ultrasound in children with chronic rheumatic diseases. A one year followup studyFernanda Falcini
Department of Pediatrics, Rheumatology Unit, University of Florence, Italy
J Rheumatol 30:179-84. 2003..To evaluate at baseline and after one year the bone status in children with chronic rheumatic diseases (CRD) using quantitative ultrasound techniques...
Osteoprotegerin serum levels in children with type 1 diabetes: a potential modulating role in bone statusFiorella Galluzzi
Department of Paediatrics, A Meyer Children's Hospital, Via Luca Giordano 13, 50132 Florence, Italy
Eur J Endocrinol 153:879-85. 2005..003). CONCLUSIONS: Prepubertal children with T1DM have a significant increase of OPG levels. OPG serum concentrations are correlated to calcaneal BUA and HbA1c values. OPG could be a new marker of reduced bone mass in children with T1DM...
Th17 transcription factor RORC2 is inversely correlated with FOXP3 expression in the joints of children with juvenile idiopathic arthritisBiagio Olivito
Department of Paediatrics, Rheumatology and Immunology Unit, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
J Rheumatol 36:2017-24. 2009..To investigate the relationship between interleukin 17 (IL-17) producing T cells (Th17) and CD4+CD25+FOXP3+ regulatory T cells (Tregs) in blood and synovial fluid (SF) of patients with juvenile idiopathic arthritis (JIA)...
Association of low bone mass with vitamin d receptor gene and calcitonin receptor gene polymorphisms in juvenile idiopathic arthritisLaura Masi
Department of Pediatrics, University of Florence, Florence, Italy
J Rheumatol 29:2225-31. 2002..To compare bone density with polymorphisms in the calcitonin receptor (CTR) and vitamin D receptor (VDR) genes in 50 patients with juvenile idiopathic arthritis and 80 matched controls...
A girl with a sore earFernanda Falcini
Department of Paediatrics-Rheumatology Unit, 50132 Florence, Italy
Lancet 362:1894. 2003
Treatment strategies for childhood noninfectious chronic uveitis: an updateLuca Cantarini
Anna Meyer Children s Hospital and University of Florence, Department of Paediatrics, Rheumatology Unit, Italy
Expert Opin Investig Drugs 21:1-6. 2012..Conclusion: Uveitis in children can be severe. Methotrexate is the drug of choice for recalcitrant cases, and biologic therapies can be useful in selected situations...
Bcl-2, p53 and c-myc expression in juvenile dermatomyositisF Falcini
Department of Paediatrics, University of Florence, Italy
Clin Exp Rheumatol 18:643-6. 2000..To investigate p53, bcl-2 and c-myc expression in muscle biopsies from children affected with juvenile dermatomyositis (JDM) and to verify a possible dysregulation of programmed cell death in this autoimmune disease...
Severe abdominal involvement as the initial manifestation of cutaneous polyarteritis nodosa in a young girlF Falcini
Department of Paediatrics, Rheumatology and Gastroenterology Unit, University of Florence, Italy
Clin Exp Rheumatol 19:349-51. 2001..Our case confirms that cutaneous PAN is often related to streptococcal infection, and suggests that ASO titers should be determined in children with vasculitides to ensure a timely diagnosis and treatment of the condition if present...
Kawasaki's disease in northern Italy: a multicenter retrospective study of 250 patientsF Falcini
Department of Paediatrics, University of Florence, Italy
Clin Exp Rheumatol 20:421-6. 2002....
Circulating leptin levels in juvenile idiopathic arthritis: a marker of nutritional status?F Perfetto
Department of Internal Medicine, Rheumatology Unit, University of Florence, 50139 Florence, Italy
Ann Rheum Dis 64:149-52. 2005..Weight loss is common in juvenile idiopathic arthritis (JIA) and has been positively correlated with an increase in the production of proinflammatory cytokines...
Bilateral renal artery stenosis in Kawasaki disease: a report of two casesF Falcini
Department of Paediatrics, Rheumatology Unit, University of Firenze, Italy
Clin Exp Rheumatol 24:719-21. 2006..Paediatricians should be alert to consider preceding KD as potential source of secondary hypertension in young infants, and raised blood pressure should be regarded as a life-threatening complication in all KD children...
Acute febrile cholestasis as an inaugural manifestation of Kawasaki's diseaseF Falcini
Rheumatology Unit, University of Florence, Florence, Italy
Clin Exp Rheumatol 18:779-80. 2000..We conclude that this syndrome should be suspected in any child with febrile cholestasis of unknown origin, in order that coronary involvement may be prevented by the administration of IVGG...
Circulating levels of the adipokines vaspin and omentin in patients with juvenile idiopathic arthritis, and relation to disease activityLuca Cantarini
Department of Clinical Medicine and Immunologic Sciences, University of Siena, Italy
Clin Exp Rheumatol 29:1044-8. 2011..The aims of our study were to evaluate their serum levels in patients affected by juvenile idiopathic arthritis (JIA), in comparison to healthy controls, and to correlate circulating levels to parameters of disease activity...
Clinical features and outcome of Cogan syndromeIlaria Pagnini
Department of Pediatrics, University of Florence, Florence, Italy
J Pediatr 160:303-307.e1. 2012..To review the clinical features of Cogan syndrome, a rare vasculitis characterized by systemic, ocular, and audiovestibular symptoms...
Early predictors of juvenile sacroiliitis in enthesitis-related arthritisIlaria Pagnini
Department of Paediatric Rheumatology, University of Florence, Anna Meyer Children s Hospital, Viale Pieraccini 24, 50139 Florence, Italy
J Rheumatol 37:2395-401. 2010..To identify early predictors of sacroiliac (SI) involvement in a cohort of patients with enthesitis-related arthritis (ERA)...
Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritisLorenzo Cosmi
University of Florence and Excellence Centre for Research, Transfer and Higher Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies, Florence, Italy
Arthritis Rheum 63:2504-15. 2011..To investigate the phenotype and function of CD4+ T cells in synovial fluid (SF) from the affected joints of children with oligoarticular-onset juvenile idiopathic arthritis (JIA), and to establish a possible link with disease activity...
Juvenile psoriatic arthritis and acquired sensorineural hearing loss in a teenager: is there an association?T Giani
Department of Paediatrics, Rheumatology Unit, University of Florence, Florence, Italy
Clin Exp Rheumatol 24:344-6. 2006..The young age of our patient seems to suggest a genetic susceptibility to autoimmunity and supports the concept of associated autoimmune diseases...
Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritisG Simonini
Department of Pediatrics, University of Florence, Italy
J Rheumatol 28:198-203. 2001....
Thyroid function, autoimmune thyroiditis and coeliac disease in juvenile idiopathic arthritisS Stagi
Department of Paediatrics, University of Florence, Italy
Rheumatology (Oxford) 44:517-20. 2005..These data seem to suggest careful monitoring of thyroid function, thyroid autoantibodies and coeliac disease in JIA children...
Prevalence and clinical significance of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritisT Avcin
Department of Paediatrics, University of Ljubljana, Slovenia, Italy
Ann Rheum Dis 61:608-11. 2002..CONCLUSIONS: Anti-CCP can be detected in children with JIA, but are less frequently present than in adults with RA...
Coeliac disease in patients with Kawasaki disease. Is there a link?S Stagi
Department of Paediatrics, Paediatric Rheumatology Unit, University of Florence, Florence, Italy
Rheumatology (Oxford) 45:847-50. 2006..However, the occurrence of a second immunological disorder in a patient with a history of KD is rarely reported. We evaluated the presence of autoimmune thyroiditis and coeliac disease (CD) in patients with KD diagnosis...
Usefulness of bone ultrasound techniques in pediatric rheumatic diseasesGabriele Simonini
J Rheumatol 32:198-9; author reply 199. 2005
Serum and synovial fluid concentrations of matrix metalloproteinases 3 and its tissue inhibitor 1 in juvenile idiopathic arthritidesMarco Gattorno
2nd Division of Pediatrics, G Gaslini Institute for Children, Genoa, Italy
J Rheumatol 29:826-31. 2002..We investigated serum and synovial fluid (SF) concentrations of MMP-3 and its tissue inhibitor (TIMP-1) in juvenile idiopathic arthritides (JIA)...
