Silvia Moretti

Summary

Affiliation: University of Florence
Country: Italy

Publications

  1. ncbi β-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines
    Silvia Moretti
    Section of Clinical, Preventive and Oncologic Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy
    Lab Invest 93:279-90. 2013
  2. ncbi Fibrosis in regressing melanoma versus nonfibrosis in halo nevus upon melanocyte disappearance: could it be related to a different cytokine microenvironment?
    Silvia Moretti
    2nd Dermatology Clinic, Department of Dermatological Sciences, University of Florence, Florence, Italy
    J Cutan Pathol 34:301-8. 2007
  3. ncbi Keratinocyte dysfunction in vitiligo epidermis: cytokine microenvironment and correlation to keratinocyte apoptosis
    Silvia Moretti
    Department of Dermatological Sciences, University of Florence, Florence, Italy
    Histol Histopathol 24:849-57. 2009
  4. ncbi Vitiligo: an update on current pharmacotherapy and future directions
    Roberta Colucci
    University of Florence, Section of Clinical, Preventive and Oncologic Dermatology, Department of Critical Care Medicine and Surgery, Florence, Italy
    Expert Opin Pharmacother 13:1885-99. 2012
  5. ncbi Sequential effects of photodynamic treatment of basal cell carcinoma
    Francesca Prignano
    Department of Dermatological Sciences, University of Florence, Florence, Italy
    J Cutan Pathol 36:409-16. 2009
  6. ncbi Red nodule on the breast
    Roberta Colucci
    Division of Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
    Indian J Dermatol 57:387-9. 2012
  7. ncbi Persistent herpes gestationis
    Samantha Berti
    The Department of Dermatological Sciences, University of Florence, Via della Pergola 58, 50121 Florence, Italy
    Skinmed 1:55-8. 2002
  8. ncbi Vitiligo in an Italian outpatient center: a clinical and serologic study of 204 patients in Tuscany
    Samantha Berti
    Department of Dermatological Sciences, University of Florence, Italy
    Am J Clin Dermatol 12:43-9. 2011
  9. ncbi Vitiligo therapy
    Torello Lotti
    University of Florence, Department of Dermatological Sciences, Via della Pergola, 60, 50121 Florence, Italy
    Expert Opin Pharmacother 10:2779-85. 2009
  10. ncbi Stem cell factor affects tumour progression markers in metastatic melanoma cells
    Francesca Prignano
    The first Dermatology Clinic, Department of Dermatological Sciences, University of Florence, Florence, Italy
    Clin Exp Metastasis 23:177-86. 2006

Collaborators

Detail Information

Publications23

  1. ncbi β-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines
    Silvia Moretti
    Section of Clinical, Preventive and Oncologic Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy
    Lab Invest 93:279-90. 2013
    ..The observation that β-ARs are upregulated in malignant melanoma tissues support the hypothesis that circulating catecholamines NE and E, by activating their receptors, favour melanoma progression in vivo...
  2. ncbi Fibrosis in regressing melanoma versus nonfibrosis in halo nevus upon melanocyte disappearance: could it be related to a different cytokine microenvironment?
    Silvia Moretti
    2nd Dermatology Clinic, Department of Dermatological Sciences, University of Florence, Florence, Italy
    J Cutan Pathol 34:301-8. 2007
    ..It is not clear why melanocyte disappearance occurs without fibrotic evolution in halo nevus and with fibrotic evolution in regressing melanoma...
  3. ncbi Keratinocyte dysfunction in vitiligo epidermis: cytokine microenvironment and correlation to keratinocyte apoptosis
    Silvia Moretti
    Department of Dermatological Sciences, University of Florence, Florence, Italy
    Histol Histopathol 24:849-57. 2009
    ..In particular, increased TNF-alpha could contribute to keratinocyte apoptosis, which results in reduced release of melanogenic cytokines and ultimately in melanocyte disappearance...
  4. ncbi Vitiligo: an update on current pharmacotherapy and future directions
    Roberta Colucci
    University of Florence, Section of Clinical, Preventive and Oncologic Dermatology, Department of Critical Care Medicine and Surgery, Florence, Italy
    Expert Opin Pharmacother 13:1885-99. 2012
    ..Other therapies, such as antioxidants, can be used in association with other therapeutic options, whereas depigmenting agents should be used only in cases of extensive vitiligo, recalcitrant to other treatments...
  5. ncbi Sequential effects of photodynamic treatment of basal cell carcinoma
    Francesca Prignano
    Department of Dermatological Sciences, University of Florence, Florence, Italy
    J Cutan Pathol 36:409-16. 2009
    ..Photodynamic therapy (PDT) of superficial basal cell carcinoma (SBCC) acts as a biological response modifier or killing target cells, but sequential biological effects have not been reported in depth in humans...
  6. ncbi Red nodule on the breast
    Roberta Colucci
    Division of Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
    Indian J Dermatol 57:387-9. 2012
    ..We report this case to highlight the importance of an investigation of Lyme borreliosis when a patient living in the countryside presents with a red nodule of the nipple and areola...
  7. ncbi Persistent herpes gestationis
    Samantha Berti
    The Department of Dermatological Sciences, University of Florence, Via della Pergola 58, 50121 Florence, Italy
    Skinmed 1:55-8. 2002
  8. ncbi Vitiligo in an Italian outpatient center: a clinical and serologic study of 204 patients in Tuscany
    Samantha Berti
    Department of Dermatological Sciences, University of Florence, Italy
    Am J Clin Dermatol 12:43-9. 2011
    ..Vitiligo is a depigmentation disorder resulting from destruction of cutaneous melanocytes that affects 0.1-2% of the world's population, irrespective of sex and race...
  9. ncbi Vitiligo therapy
    Torello Lotti
    University of Florence, Department of Dermatological Sciences, Via della Pergola, 60, 50121 Florence, Italy
    Expert Opin Pharmacother 10:2779-85. 2009
    ..Excellent therapeutic results can be achieved through combination treatments; surgical intervention is reserved for adolescent or adult patients with stable vitiligo...
  10. ncbi Stem cell factor affects tumour progression markers in metastatic melanoma cells
    Francesca Prignano
    The first Dermatology Clinic, Department of Dermatological Sciences, University of Florence, Florence, Italy
    Clin Exp Metastasis 23:177-86. 2006
    ..Taken altogether these data stress the biological activity of SCF as a cytokine which is able to maintain MMC in a well differentiated status, and suggest a more in depth evaluation of possible effects of SCF on melanoma cells...
  11. ncbi Highlights of thirty-year experience of CO2 laser use at the Florence (Italy) department of dermatology
    Piero Campolmi
    Section of Clinical, Preventive and Oncologic Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Villa S Chiara, Piazza indipendenza 11, 50129 Florence, Italy
    ScientificWorldJournal 2012:546528. 2012
    ..Our results are at times not consistent with those published in the literature, stressing the concept that multicentric studies that harmonization methodology and the patient selection are vital...
  12. ncbi Genetic screening test for psoriatic arthritis and UVB irradiation potential responders: A new tool to identify psoriasis subpopulation patients?
    Torello Lotti
    Department of Critical Care Medicine and Surgery, Division of Clinical, Preventive and Oncologic Dermatology, University of Florence, Italy
    Indian Dermatol Online J 2:57-63. 2011
    ..Genetic tests today represent a reliable investigation procedure which could rapidly and consistently improve the diagnostic ability of the dermatologist and contribute to the early and correct treatment of the different subsets of PsA...
  13. ncbi A case of chronic herpes gestationis: persistent disease or conversion to bullous pemphigoid?
    Lauretta Amato
    Department of Dermatology, University of Florence, Florence, Italy
    J Am Acad Dermatol 49:302-7. 2003
    ..We present this case as chronic persistent HG and discuss the differential diagnosis between chronic persistent HG and HG evolving to bullous pemphigoid, together with a careful examination of similar cases reported in literature...
  14. ncbi New insights into the pathogenesis of vitiligo: imbalance of epidermal cytokines at sites of lesions
    Silvia Moretti
    2nd Dermatology Unit, SM Nuova Hospital, Azienda Sanitaria di Firenze, Florence, Italy
    Pigment Cell Res 15:87-92. 2002
    ....
  15. ncbi Increased oxidative DNA damage in mononuclear leukocytes in vitiligo
    Lisa Giovannelli
    Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Firenze, Florence, Italy
    Mutat Res 556:101-6. 2004
    ..However, these findings support an adjuvant role of antioxidant treatment in vitiligo...
  16. ncbi Subacute cutaneous lupus erythematosus in childhood
    Lauretta Amato
    Department of Dermatological Sciences, University of Florence, Florence, Italy
    Pediatr Dermatol 20:31-4. 2003
    ..Treatment with hydroxychloroquine cleared the cutaneous lesions. We report this patient because SCLE is extremely rare in childhood, and discuss the two previous cases reported in the literature...
  17. ncbi Vitiligo: new and emerging treatments
    Torello Lotti
    Department of Dermatological Sciences, University of Florence, Florence, Italy
    Dermatol Ther 21:110-7. 2008
    ..Finally, for patients with extensive vitiligo, depigmentation of the residual melanin should be taken into account...
  18. ncbi Potential Infectious Etiology of Behçet's Disease
    Massimiliano Galeone
    Department of Dermatological Sciences, University of Florence, Florence 50129, Italy
    Patholog Res Int 2012:595380. 2012
    ..Several viral agents, including herpes simplex virus-1, hepatitis C virus, parvovirus B19, cytomegalovirus, Epstein-Barr virus and varicella zoster virus, may also have some role...
  19. ncbi Vitiligo and epidermal microenvironment: possible involvement of keratinocyte-derived cytokines
    Silvia Moretti
    Arch Dermatol 138:273-4. 2002
  20. ncbi Receptors and pathways in innate antifungal immunity: the implication for tolerance and immunity to fungi
    Teresa Zelante
    Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
    Adv Exp Med Biol 590:209-21. 2007
  21. ncbi Seasonal variations of DNA damage in human lymphocytes: correlation with different environmental variables
    Lisa Giovannelli
    Dipartimento di Farmacologia Preclinica e Clinica, , Viale Pieraccini 6, 50139 Firenze, Italy
    Mutat Res 593:143-52. 2006
    ..The results of multivariate regression analysis showed a positive correlation between lymphocyte DNA damage and air temperature, and a less strong correlation with global solar radiation and air ozone levels...
  22. ncbi TLRs govern neutrophil activity in aspergillosis
    Silvia Bellocchio
    Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
    J Immunol 173:7406-15. 2004
    ..The ability of selected individual TLRs to restore antifungal functions in defective PMNs suggests that the coordinated outputs of activation of multiple TLRs may contribute to PMN function in aspergillosis...
  23. ncbi Thymosin alpha1 activates the TLR9/MyD88/IRF7-dependent murine cytomegalovirus sensing for induction of anti-viral responses in vivo
    Silvia Bozza
    Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Via del Giochetto, 06122 Perugia, Perugia, Italy
    Int Immunol 19:1261-70. 2007
    ....