Susanna Morano

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. doi request reprint Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes
    Elisabetta Mandosi
    a 1 Sapienza University of Rome, Policlinico Umberto I, Department of Experimental Medicine, Viale del Policlinico 155, 00161, Rome, Italy 390 649 978 381 390 649 978 381
    Expert Opin Ther Targets 19:1617-22. 2015
  2. doi request reprint Short-term effects of glucagon-like peptide 1 (GLP-1) receptor agonists on fat distribution in patients with type 2 diabetes mellitus: an ultrasonography study
    Susanna Morano
    Department of Experimental Medicine, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161, Rome, Italy
    Acta Diabetol 52:727-32. 2015
  3. ncbi request reprint Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study
    Susanna Morano
    Department of Clinical Sciences, Sapienza University, Rome, Italy
    Eur Urol 52:1768-74. 2007
  4. ncbi request reprint Circulating monocyte oxidative activity is increased in patients with type 2 diabetes and erectile dysfunction
    Susanna Morano
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    J Urol 177:655-9. 2007
  5. ncbi request reprint Angiotensin blockade and matrix synthesis by glomerular epithelial cells in high glucose: a further experimental insight into the pathophysiology of diabetic nephropathy
    S Morano
    Department of Clinical Sciences, Endocrinology, Clinica Medica 2, La Sapienza University, Rome, Italy
    Clin Ter 159:151-4. 2008
  6. ncbi request reprint Angiotensin-converting enzyme inhibition modulates high-glucose-induced extracellular matrix changes in mouse glomerular epithelial cells
    S Morano
    Division of Endocrinology, Department of Clinical Sciences, Clinica Medica 2, Rome, Italy
    Nephron Exp Nephrol 95:e30-5. 2003
  7. ncbi request reprint Pathophysiology of diabetic sexual dysfunction
    S Morano
    Department of Clinical Sciences, Endocrinology, University La Sapienza, Rome, Italy
    J Endocrinol Invest 26:65-9. 2003
  8. pmc Hemoglobin A1c variability as an independent correlate of cardiovascular disease in patients with type 2 diabetes: a cross-sectional analysis of the renal insufficiency and cardiovascular events (RIACE) Italian multicenter study
    Giuseppe Penno
    Department of Clinical and Molecular Medicine, La Sapienza University, Rome, Italy
    Cardiovasc Diabetol 12:98. 2013
  9. ncbi request reprint Endothelial dysfunction and oxidative stress in type 1 and type 2 diabetic patients without clinical macrovascular complications
    Giancarlo De Mattia
    Department of Internal Medicine, Policlinico Umberto I, Sapienza University, Viale del Policlinico 155, 00161 Rome, Italy
    Diabetes Res Clin Pract 79:337-42. 2008
  10. pmc Poor glycemic control is an independent risk factor for low HDL cholesterol in patients with type 2 diabetes
    Alessandra Gatti
    Department of Clinical Sciences, Sapienza University of Rome, Rome, Italy
    Diabetes Care 32:1550-2. 2009

Collaborators

Detail Information

Publications26

  1. doi request reprint Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes
    Elisabetta Mandosi
    a 1 Sapienza University of Rome, Policlinico Umberto I, Department of Experimental Medicine, Viale del Policlinico 155, 00161, Rome, Italy 390 649 978 381 390 649 978 381
    Expert Opin Ther Targets 19:1617-22. 2015
    ..The effect of chronic sildenafil treatment, on ED markers and metabolic parameters in a non-randomized study on men with type 2 diabetes (T2DM), was investigated...
  2. doi request reprint Short-term effects of glucagon-like peptide 1 (GLP-1) receptor agonists on fat distribution in patients with type 2 diabetes mellitus: an ultrasonography study
    Susanna Morano
    Department of Experimental Medicine, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161, Rome, Italy
    Acta Diabetol 52:727-32. 2015
    ..Glucagon-like peptide 1 receptor agonists (GLP-1 RA) induce weight loss and reduction in adipose tissue, but the effects of GLP-1 RA on the distribution of fat deposits have been poorly investigated...
  3. ncbi request reprint Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study
    Susanna Morano
    Department of Clinical Sciences, Sapienza University, Rome, Italy
    Eur Urol 52:1768-74. 2007
    ..To investigate the synergic effect of propionyl L-carnitine (PLC) plus sildenafil in reducing monocyte oxidative activity and endothelial dysfunction markers in diabetic patients with erectile dysfunction (ED)...
  4. ncbi request reprint Circulating monocyte oxidative activity is increased in patients with type 2 diabetes and erectile dysfunction
    Susanna Morano
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    J Urol 177:655-9. 2007
    ..We investigated the relationship between oxidative stress and diabetic erectile dysfunction...
  5. ncbi request reprint Angiotensin blockade and matrix synthesis by glomerular epithelial cells in high glucose: a further experimental insight into the pathophysiology of diabetic nephropathy
    S Morano
    Department of Clinical Sciences, Endocrinology, Clinica Medica 2, La Sapienza University, Rome, Italy
    Clin Ter 159:151-4. 2008
    ..One of the major pathogenic events in this condition is represented by the alteration of the extracellular matrix protein synthesis by glomerular epithelial cells...
  6. ncbi request reprint Angiotensin-converting enzyme inhibition modulates high-glucose-induced extracellular matrix changes in mouse glomerular epithelial cells
    S Morano
    Division of Endocrinology, Department of Clinical Sciences, Clinica Medica 2, Rome, Italy
    Nephron Exp Nephrol 95:e30-5. 2003
    ..We evaluated the effects of high glucose concentrations and inhibition of angiotensin-converting enzyme on the laminin and fibronectin production by glomerular epithelial cells...
  7. ncbi request reprint Pathophysiology of diabetic sexual dysfunction
    S Morano
    Department of Clinical Sciences, Endocrinology, University La Sapienza, Rome, Italy
    J Endocrinol Invest 26:65-9. 2003
    ..Sexual dysfunction is associated with lower overall quality of marital relation and more depressive symptoms in diabetic women...
  8. pmc Hemoglobin A1c variability as an independent correlate of cardiovascular disease in patients with type 2 diabetes: a cross-sectional analysis of the renal insufficiency and cardiovascular events (RIACE) Italian multicenter study
    Giuseppe Penno
    Department of Clinical and Molecular Medicine, La Sapienza University, Rome, Italy
    Cardiovasc Diabetol 12:98. 2013
    ....
  9. ncbi request reprint Endothelial dysfunction and oxidative stress in type 1 and type 2 diabetic patients without clinical macrovascular complications
    Giancarlo De Mattia
    Department of Internal Medicine, Policlinico Umberto I, Sapienza University, Viale del Policlinico 155, 00161 Rome, Italy
    Diabetes Res Clin Pract 79:337-42. 2008
    ..To evaluate the relationship between oxidative stress and endothelial dysfunction (ED) in diabetic patients without clinical macrovascular complications...
  10. pmc Poor glycemic control is an independent risk factor for low HDL cholesterol in patients with type 2 diabetes
    Alessandra Gatti
    Department of Clinical Sciences, Sapienza University of Rome, Rome, Italy
    Diabetes Care 32:1550-2. 2009
    ..12 [1.05-1.18], P = 0.00017). CONCLUSIONS Poor glycemic control appears to be an independent risk factor for low HDL cholesterol in type 2 diabetes...
  11. ncbi request reprint Atorvastatin downregulates monocyte CD36 expression, nuclear NFkappaB and TNFalpha levels in type 2 diabetes
    Elisabetta Mandosi
    Department of Clinical Sciences, Sapienza University of Rome, Rome, Italy
    J Atheroscler Thromb 17:539-45. 2010
    ....
  12. doi request reprint Chronic Inhibition of cGMP phosphodiesterase 5A improves diabetic cardiomyopathy: a randomized, controlled clinical trial using magnetic resonance imaging with myocardial tagging
    Elisa Giannetta
    Department of Experimental Medicine, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy
    Circulation 125:2323-33. 2012
    ..We explored the cardioreparative properties of a selective phosphodiesterase type 5 inhibitor, sildenafil, in a model of diabetic cardiomyopathy...
  13. pmc IgA anti-transglutaminase autoantibodies at type 1 diabetes onset are less frequent in adult patients and are associated with a general celiac-specific lower immune response in comparison with nondiabetic celiac patients at diagnosis
    Claudio Tiberti
    Department of Internal Medicine, University of Rome Sapienza, Rome, Italy
    Diabetes Care 35:2083-5. 2012
    ....
  14. doi request reprint Long-standing type 1 diabetes: patients with adult-onset develop celiac-specific immunoreactivity more frequently than patients with childhood-onset diabetes, in a disease duration-dependent manner
    Claudio Tiberti
    Department of Internal Medicine, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161, Rome, Italy
    Acta Diabetol 51:675-8. 2014
    ..7 vs 4.2 % (CH)LDM1, p = 0.043). Celiac disease humoral immunoreactivity should be screened not only at diabetes onset, but also in long-standing patients, especially adults with disease duration >15 years. ..
  15. doi request reprint High prevalence of advanced retinopathy in patients with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study
    Giuseppe Pugliese
    Department of Clinical and Molecular Medicine, La Sapienza University, Rome, Italy
    Diabetes Res Clin Pract 98:329-37. 2012
    ..This study aimed at assessing prevalence of advanced DR and its correlation with risk factors and complications in subjects with type 2 diabetes from the Renal Insufficiency and Cardiovascular Events (RIACE) Italian Multicenter Study...
  16. doi request reprint The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation provides a better definition of cardiovascular burden associated with CKD than the Modification of Diet in Renal Disease (MDRD) Study formula in subjects with type 2 diabetes
    Giuseppe Pugliese
    Department of Clinical and Molecular Medicine, La Sapienza University, Rome, Italy
    Atherosclerosis 218:194-9. 2011
    ..This study was aimed at assessing cardiovascular disease (CVD) burden associated with CKD in type 2 diabetes, using these two GFR estimating formulas for CKD definition...
  17. ncbi request reprint Poly(ADP-ribose)polymerase activity is reduced in circulating mononuclear cells from type 2 diabetic patients
    Italo Tempera
    Department of Biochemical Sciences, University La Sapienza, Roma, Italy
    J Cell Physiol 205:387-92. 2005
    ..0001). The different PARP-1 behavior in MNCs from patients with type 2 diabetes could therefore be responsible for the abnormal inflammation and infection responses in diabetes...
  18. doi request reprint Effect of insulin on airway responsiveness in patients with type 2 diabetes mellitus: a cohort study
    Claudio Terzano
    Department of Cardiovascular and Respiratory Sciences, Respiratory Diseases Unit, Fondazione E Lorillard Spencer Cenci, Sapienza University of Rome, Italy
    J Asthma 46:703-7. 2009
    ..We designed a cohort study with the aim of evaluating the effects of insulin therapy on airway responsiveness (AR) in human patients with type 2 diabetes mellitus...
  19. ncbi request reprint High circulating vascular endothelial growth factor (VEGF) is related to a better systolic function in diabetic hypertensive patients
    Gianluca Iacobellis
    Endocrinology, Department of Clinical Sciences, La Sapienza University, Rome, Italy
    Cytokine 27:25-30. 2004
    ..We sought to test the hypothesis that circulating VEGF levels could influence the cardiac performance in type 2 diabetic hypertensive patients...
  20. doi request reprint Metabolic syndrome is not a risk factor for kidney dysfunction in obese non-diabetic subjects
    Alessandra Gatti
    Department of Clinical Sciences, Sapienza University, Rome, Italy
    Obesity (Silver Spring) 16:899-901. 2008
    ..To investigate whether insulin resistance (IR) and the metabolic syndrome (MS) are associated with kidney dysfunction in obese non-diabetic (OND) subjects...
  21. doi request reprint Lack of the QTc physiologic decrease during cardiac stress test in patients with type 2 diabetes treated with secretagogues
    Mario Curione
    Sapienza University, Rome, RM, Italy
    Acta Diabetol 51:31-3. 2014
    ..These results suggest to evaluate, in these patients, QT length, even during routine cardiac stress test. ..
  22. doi request reprint GAD and IA-2 autoantibody detection in type 1 diabetic patient saliva
    Claudio Tiberti
    Department of Clinical Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
    Clin Immunol 131:271-6. 2009
    ....
  23. doi request reprint Development and validation of a 6-item version of the female sexual function index (FSFI) as a diagnostic tool for female sexual dysfunction
    Andrea M Isidori
    Department of Medical Pathophysiology, University of Rome La Sapienza, Rome, Italy
    J Sex Med 7:1139-46. 2010
    ..Often, practitioners avoid investigating sexual symptoms due to concerns of insufficient time or lack of proper tools to address FSD...
  24. doi request reprint Measurement of the thickness of the urethrovaginal space in women with or without vaginal orgasm
    Giovanni Luca Gravina
    Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
    J Sex Med 5:610-8. 2008
    ..The physiology and anatomy of female sexual function are poorly understood. The differences in sexual function among women may be partly attributed to anatomical factors...
  25. ncbi request reprint Early detection of small-fiber neuropathy in diabetes: a laser-induced pain somatosensory-evoked potentials and pupillometric study
    Giuseppe Pozzessere
    Institute of Neurology, University La Sapienza, Rome, Italy
    Diabetes Care 25:2355-8. 2002
  26. ncbi request reprint Pre-perceptual pain sensory responses (N1 component) in type 1 diabetes mellitus
    Paolo Rossi
    Institute of Neurology, La Sapienza, Viale dell Universita 30, 00185, Rome, Italy
    Neuroreport 13:1009-12. 2002
    ..N1 and P2 potentials are delayed and decreased in parallel giving evidence that LEP abnormalities are not secondary to a cognitive dysfunction and mostly reflect a small-fiber dysfunction...