E Monti

Summary

Affiliation: University of Brescia
Country: Italy

Publications

  1. ncbi request reprint Recent development in mammalian sialidase molecular biology
    Eugenio Monti
    Department of Biomedical Sciences and Biotechnology, University of Brescia, Italy
    Neurochem Res 27:649-63. 2002
  2. pmc New insights on the sialidase protein family revealed by a phylogenetic analysis in metazoa
    Edoardo Giacopuzzi
    Department of Biomedical Sciences and Biotechnology, Unit of Biology and Genetics, University of Brescia, Brescia, Italy
    PLoS ONE 7:e44193. 2012
  3. pmc Implications for the mammalian sialidases in the physiopathology of skeletal muscle
    Alessandro Fanzani
    Department of Biomedical Sciences and Biotechnologies and Interuniversitary Institute of Myology IIM, University of Brescia, Viale Europa 11, 25123, Brescia, Italy
    Skelet Muscle 2:23. 2012
  4. pmc Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops
    Edoardo Giacopuzzi
    Department of Biomedical Sciences and Biotechnology, Unit of Biology and Genetics, University of Brescia, Viale Europa 11, Brescia 25123, Italy
    BMC Biochem 12:45. 2011
  5. ncbi request reprint Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family
    E Monti
    Department of Biomedical Science and Biotechnology, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Genomics 83:445-53. 2004
  6. pmc Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane
    E Monti
    Telethon Institute of Genetics and Medicine TIGEM, San Raffaele Biomedical Science Park, Via Olgettina 58, 20132 Milan, Italy and Department of Biomedical Science and Biotechnology, University of Brescia, Via Valsabbina 19, 25123 Brescia, Italy
    Biochem J 349:343-51. 2000
  7. ncbi request reprint Overexpression of wild-type and mutant mucolipin proteins in mammalian cells: effects on the late endocytic compartment organization
    M Manzoni
    Sezione di Biologia e Genetica, Dipartimento di Scienze Biomediche e Biotecnologie, Viale Europa 11, 25123 Brescia, Italy
    FEBS Lett 567:219-24. 2004
  8. pmc Sialidase NEU3 is a peripheral membrane protein localized on the cell surface and in endosomal structures
    Gabriele Zanchetti
    Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Biochem J 408:211-9. 2007
  9. pmc Molecular cloning and biochemical characterization of sialidases from zebrafish (Danio rerio)
    Marta Manzoni
    Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Biochem J 408:395-406. 2007
  10. ncbi request reprint The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions
    Nadia Papini
    Department of Medical Chemistry, Center of Excellence on Neurodegenerative Diseases, School of Medicine, University of Milan, 20090 Segrate, Italy
    J Biol Chem 279:16989-95. 2004

Collaborators

  • G Tettamanti
  • S Barlati
  • Giuseppe Borsani
  • Bruno Venerando
  • T Miyagi
  • F Berditchevski
  • Cristina Tringali
  • Nadia Papini
  • Luigi Anastasia
  • Roberto Bresciani
  • Edoardo Giacopuzzi
  • Augusto Preti
  • Marta Manzoni
  • Alessandro Fanzani
  • Maurilio Sampaolesi
  • Anna Bianchi
  • Gabriele Zanchetti
  • Paolo Colombi
  • Elena Odintsova
  • Maria Teresa Bassi
  • Leonard M G Chavas
  • Paola Fusi
  • Gianluigi Croci
  • M Manzoni
  • Alessandra Zanola
  • Roland Schauer
  • Fiorella Faggi
  • Enrique Villar
  • Javier Holguera
  • Isabel Muñoz-Barroso
  • Francesca D'Avila
  • Maria Domenica Cappellini
  • Luigi Caimi
  • Francesco Argenton
  • Barbara Lupo
  • Natascia Tiso
  • Luisa Ronzoni
  • Luana Rubaga
  • Giulio Cossu
  • Giuseppe Lamorte
  • Terry D Butters
  • Daniela Galli
  • Gerrit van Meer
  • Hein Sprong
  • Diego Oleari
  • Maria Teresa Pizzo
  • Antonella Della Monica
  • Ryuichi Kato
  • Soichi Wakatsuki
  • Kazunori Yamaguchi
  • R Bresciani
  • M T Bassi
  • Sandro Sonnino
  • Simona Prioni
  • Alessandro Prinetti
  • Paolo Tortora
  • A Bozzato

Detail Information

Publications18

  1. ncbi request reprint Recent development in mammalian sialidase molecular biology
    Eugenio Monti
    Department of Biomedical Sciences and Biotechnology, University of Brescia, Italy
    Neurochem Res 27:649-63. 2002
    ..Overall, the availability of the cDNA species encoding mammalian sialidases is an important step leading toward a comprehensive picture of the relationships between the structure and biological function of these enzymes...
  2. pmc New insights on the sialidase protein family revealed by a phylogenetic analysis in metazoa
    Edoardo Giacopuzzi
    Department of Biomedical Sciences and Biotechnology, Unit of Biology and Genetics, University of Brescia, Brescia, Italy
    PLoS ONE 7:e44193. 2012
    ..Moreover, we further confirm findings on the catalytic residues and identified enzyme loop portions that behave as rapidly diverging regions and may be involved in the evolution of specific properties of sialidases...
  3. pmc Implications for the mammalian sialidases in the physiopathology of skeletal muscle
    Alessandro Fanzani
    Department of Biomedical Sciences and Biotechnologies and Interuniversitary Institute of Myology IIM, University of Brescia, Viale Europa 11, 25123, Brescia, Italy
    Skelet Muscle 2:23. 2012
    ....
  4. pmc Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops
    Edoardo Giacopuzzi
    Department of Biomedical Sciences and Biotechnology, Unit of Biology and Genetics, University of Brescia, Viale Europa 11, Brescia 25123, Italy
    BMC Biochem 12:45. 2011
    ..These features prompted us to extend our studies on this protein family in birds, to get insights on the evolution of this class of glycohydrolases...
  5. ncbi request reprint Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family
    E Monti
    Department of Biomedical Science and Biotechnology, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Genomics 83:445-53. 2004
    ..Immunofluorescence staining and Western blot analysis demonstrated the association of NEU4 with the inner cell membranes...
  6. pmc Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane
    E Monti
    Telethon Institute of Genetics and Medicine TIGEM, San Raffaele Biomedical Science Park, Via Olgettina 58, 20132 Milan, Italy and Department of Biomedical Science and Biotechnology, University of Brescia, Via Valsabbina 19, 25123 Brescia, Italy
    Biochem J 349:343-51. 2000
    ..8. Immunofluorescence staining of the transfected COS7 cells demonstrated the protein's localization in the plasma membrane...
  7. ncbi request reprint Overexpression of wild-type and mutant mucolipin proteins in mammalian cells: effects on the late endocytic compartment organization
    M Manzoni
    Sezione di Biologia e Genetica, Dipartimento di Scienze Biomediche e Biotecnologie, Viale Europa 11, 25123 Brescia, Italy
    FEBS Lett 567:219-24. 2004
    ..Among the mutants, only F408del induces a redistribution of the late endocytic compartment. These findings suggest that the overexpression of the mucolipin cation channel influences the dynamic equilibrium of late endocytic compartments...
  8. pmc Sialidase NEU3 is a peripheral membrane protein localized on the cell surface and in endosomal structures
    Gabriele Zanchetti
    Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Biochem J 408:211-9. 2007
    ..Overall, these results provide important information about the biology of NEU3, the most studied member of the mammalian sialidase family...
  9. pmc Molecular cloning and biochemical characterization of sialidases from zebrafish (Danio rerio)
    Marta Manzoni
    Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Biochem J 408:395-406. 2007
    ..Overall, the redundancy of sialidases together with their expression profile and their activity exerted on gangliosides of living cells indicate the biological relevance of this class of enzymes in zebrafish...
  10. ncbi request reprint The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions
    Nadia Papini
    Department of Medical Chemistry, Center of Excellence on Neurodegenerative Diseases, School of Medicine, University of Milan, 20090 Segrate, Italy
    J Biol Chem 279:16989-95. 2004
    ..These results indicate that the plasma membrane-associated sialidase MmNEU3 is able to hydrolyze ganglioside substrates in intact living cells at a neutral pH, mainly through cell-to-cell interactions...
  11. ncbi request reprint Over-expression of mammalian sialidase NEU3 reduces Newcastle disease virus entry and propagation in COS7 cells
    Luigi Anastasia
    Department of Medical Chemistry, Biochemistry and Biotechnology, University of Milan, Milan, Italy
    Biochim Biophys Acta 1780:504-12. 2008
    ..Evidence was also provided for the preferential association of NDV-HN at 4 degrees C to detergent resistant microdomains (DRMs) of COS7 cells plasma membranes...
  12. ncbi request reprint Properties of recombinant human cytosolic sialidase HsNEU2. The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules
    Cristina Tringali
    Department of Medical Chemistry, Biochemistry, and Biotechnology, University of Milan, Medical Faculty, Laboratorio Interdisciplinare Tecnologie Avanzate L I T A Segrate, Via Fratelli Cervi 93, 20090 Segrate, Milan, Italy
    J Biol Chem 279:3169-79. 2004
    ..The last ability might be relevant in sialidase interactions with gangliosides under physiological conditions...
  13. ncbi request reprint Crystal structure of the human cytosolic sialidase Neu2. Evidence for the dynamic nature of substrate recognition
    Leonard M G Chavas
    Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization, Tsukuba, Ibaraki 305 0801, Japan
    J Biol Chem 280:469-75. 2005
    ....
  14. ncbi request reprint Expression of sialidase Neu2 in leukemic K562 cells induces apoptosis by impairing Bcr-Abl/Src kinases signaling
    Cristina Tringali
    Department of Medical Chemistry, Biochemistry and Biotechnology, University of Milan, LITA via Fratelli Cervi 93, Segrate, Milan, Italy
    J Biol Chem 282:14364-72. 2007
    ..In fact, three cytosolic glycoproteins, in the range 45-66 kDa, showed a 50-70% decrease of their sialic acid content upon Neu2 expression, supporting their possible role as modulators of the Bcr-Abl complex...
  15. ncbi request reprint Modification of sialidase levels and sialoglycoconjugate pattern during erythroid and erytroleukemic cell differentiation
    Cristina Tringali
    Department of Medical Chemistry, Biochemistry and Biotechnology, Faculty of Exercise Science, University of Milan, LITA Segrate, Via Fratelli Cervi 93, 20090 Segrate, Milan, Italy
    Glycoconj J 24:67-79. 2007
    ..Overall, these results point out the great differences in sialoglycoconjugate and sialidase patterns exhibited by normal and tumour cells...
  16. ncbi request reprint Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle
    Luigi Anastasia
    Department of Medical Chemistry, Biochemistry and Biotechnology, University of Milan, L I T A via F lli Cervi 93, 20090 Segrate, Milan, Italy
    Cell Death Differ 13:2042-51. 2006
    ..Moreover, this is the first study to demonstrate that plasticity changes arise in primary mouse and human cells following reversine exposure...
  17. ncbi request reprint Cellular expression and alternative splicing of SLC25A23, a member of the mitochondrial Ca2+-dependent solute carrier gene family
    Maria Teresa Bassi
    Istituto Scientifico Eugenio Medea La Nostra Famiglia, Via Don Luigi Monza, 20 22040 Bosisio Parini LC, Italy
    Gene 345:173-82. 2005
    ..We believe that our study will contribute to a better knowledge of this family of mitochondrial carriers...
  18. pmc Gangliosides play an important role in the organization of CD82-enriched microdomains
    Elena Odintsova
    Cancer Research U K Institute for Cancer Studies, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Biochem J 400:315-25. 2006
    ..Furthermore, these results demonstrate that the association between different tetraspanins in TERM is controlled by distinct mechanisms and identify Neu3 as a first physiological regulator of the integrity of these microdomains...