Luigi Mondello


Affiliation: University of Messina
Country: Italy


  1. Zheljazkov V, Micalizzi G, Semerdjieva I, Mondello L. Chemical Composition of the Essential Oil of the Endemic Species Micromeria frivaldszkyana (Degen) Velen. Molecules. 2019;24: pubmed publisher
    ..frivaldszkyana EO yield and composition. The EO showed some similarities with the chemical profile of other Micromeria species, but overall, it has an unique chemical profile and may have distinctive applications. ..
  2. Zoccali M, Tranchida P, Mondello L. On-line liquid chromatography-comprehensive two dimensional gas chromatography with dual detection for the analysis of mineral oil and synthetic hydrocarbons in cosmetic lip care products. Anal Chim Acta. 2019;1048:221-226 pubmed publisher
    ..7 to 44.4% (CV values were in the 1.5-5.4% range) while MOAH contamination was found in four samples, ranging from 386 to 5869 mg kg-1 (CV values were in the 0.5-4.5% range). ..
  3. Fanali C, Della Posta S, Vilmercati A, Dugo L, Russo M, Petitti T, et al. Extraction, Analysis, and Antioxidant Activity Evaluation of Phenolic Compounds in Different Italian Extra-Virgin Olive Oils. Molecules. 2018;23: pubmed publisher
    ..This was studied performing statistical analysis by one-way analysis of variance (ANOVA) followed by Bonferroni post-hoc test. ..
  4. Costa R, Beccaria M, Grasso E, Albergamo A, Oteri M, Dugo P, et al. Sample preparation techniques coupled to advanced chromatographic methods for marine organisms investigation. Anal Chim Acta. 2015;875:41-53 pubmed publisher
    ..In particular, with respect to HPLC, mass spectrometry with atmospheric pressure chemical ionization in positive mode was applied. ..
  5. Franchina F, Maimone M, Sciarrone D, Purcaro G, Tranchida P, Mondello L. Evaluation of a novel helium ionization detector within the context of (low-)flow modulation comprehensive two-dimensional gas chromatography. J Chromatogr A. 2015;1402:102-9 pubmed publisher
    ..Particular attention was devoted to the behaviour of the FM GC×GC-BID system toward saturated and aromatic hydrocarbons, for a possible future use in the field of mineral-oil food contamination research. ..
  6. Tranchida P, Franchina F, Dugo P, Mondello L. Flow-modulation low-pressure comprehensive two-dimensional gas chromatography. J Chromatogr A. 2014;1372C:236-244 pubmed publisher
    ..g., 51cm), a modification that greatly improved the general post-modulation peak shape quality. FM GC×LP GC-qMS applications on pure standard compounds, as well as on milk and fish oil fatty acid methyl esters, are shown and discussed. ..
  7. Donato P, Micalizzi G, Oteri M, Rigano F, Sciarrone D, Dugo P, et al. Comprehensive lipid profiling in the Mediterranean mussel (Mytilus galloprovincialis) using hyphenated and multidimensional chromatography techniques coupled to mass spectrometry detection. Anal Bioanal Chem. 2018;410:3297-3313 pubmed publisher
    ..25 mm, 0.2 ?m d f ionic liquid column. ..
  8. Zoccali M, Cappello S, Mondello L. Multilevel characterization of marine microbial biodegradation potentiality by means of flow-modulated comprehensive two-dimensional gas chromatography combined with a triple quadrupole mass spectrometer. J Chromatogr A. 2018;1547:99-106 pubmed publisher
    ..Progressive degradation of linear, branched, and aromatic hydrocarbons, adamantanes, and diamantanes has been showed, whereas, results underline the lack of any kind of activity against steranes, and hopanes. ..
  9. Pantò S, Sciarrone D, Maimone M, Ragonese C, Giofrè S, Donato P, et al. Performance evaluation of a versatile multidimensional chromatographic preparative system based on three-dimensional gas chromatography and liquid chromatography-two-dimensional gas chromatography for the collection of volatile constituents. J Chromatogr A. 2015;1417:96-103 pubmed publisher
    ..All target compounds, whose determination is hampered by the unavailability of commercial standards, were collected at milligram levels and with a high degree of purity (>87%). ..

More Information


  1. Franchina F, Machado M, Tranchida P, Zini C, Caramão E, Mondello L. Determination of aromatic sulphur compounds in heavy gas oil by using (low-)flow modulated comprehensive two-dimensional gas chromatography-triple quadrupole mass spectrometry. J Chromatogr A. 2015;1387:86-94 pubmed publisher
    ..The highest limit of quantification was calculated to be 299 μg/L (for the C1-benzothiophene class), while the lowest was 21 μg/L (for the C4-benzothiophene class). ..
  2. Donato P, Rigano F, Cacciola F, Schure M, Farnetti S, Russo M, et al. Comprehensive two-dimensional liquid chromatography-tandem mass spectrometry for the simultaneous determination of wine polyphenols and target contaminants. J Chromatogr A. 2016;1458:54-62 pubmed publisher
    ..The estimated limits of detection and of quantification were 0.3?gL(-1) and 1?gL(-1), respectively, well below the minimum detection limit (10?gL(-1)) set by current regulation. ..
  3. Bonaccorsi I, Cacciola F, Utczás M, Inferrera V, Giuffrida D, Donato P, et al. Characterization of the pigment fraction in sweet bell peppers (Capsicum annuum L.) harvested at green and overripe yellow and red stages by offline multidimensional convergence chromatography/liquid chromatography-mass spectrometry. J Sep Sci. 2016;39:3281-91 pubmed publisher
  4. Aguennouz M, Beccaria M, Purcaro G, Oteri M, Micalizzi G, Musumesci O, et al. Analysis of lipid profile in lipid storage myopathy. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1029-1030:157-168 pubmed publisher
    ..Using component 1 vs component 3 a 43.3% of total variance was explained. Such results suggest the important role that lipid profile characterization can have in supporting a correct diagnosis. ..
  5. Albergamo A, Rigano F, Purcaro G, Mauceri A, Fasulo S, Mondello L. Free fatty acid profiling of marine sentinels by nanoLC-EI-MS for the assessment of environmental pollution effects. Sci Total Environ. 2016;571:955-62 pubmed publisher
    ..g. alteration of the fatty acid biosynthetic system and lipotoxicity) and explain adverse and compromising effects (e.g. oxidative stress and inflammatory processes) related to environmental pollution. ..
  6. Sciarrone D, Pantò S, Donato P, Mondello L. Improving the productivity of a multidimensional chromatographic preparative system by collecting pure chemicals after each of three chromatographic dimensions. J Chromatogr A. 2016;1475:80-85 pubmed publisher
    ..Purity levels ranging from 85 to 95% were achieved with an average collection recovery of 90% (n=5). The following average amounts were collected per run: 160?g for ?-guaiene, 295?g for ?-bulnesene, and 496?g for patchouli alcohol. ..
  7. Franchina F, Maimone M, Tranchida P, Mondello L. Flow modulation comprehensive two-dimensional gas chromatography-mass spectrometry using ≈4 mL min(-1) gas flows. J Chromatogr A. 2016;1441:134-9 pubmed publisher
    ..It was observed that signal intensities were, in general, considerably higher in the FM GC×GC-MS experiments. ..
  8. Tranchida P, Maimone M, Franchina F, Bjerk T, Zini C, Purcaro G, et al. Four-stage (low-)flow modulation comprehensive gas chromatography-quadrupole mass spectrometry for the determination of recently-highlighted cosmetic allergens. J Chromatogr A. 2016;1439:144-151 pubmed publisher
    ..Finally, the FM GC×GC-qMS method was used not only for the quantification of target allergens in five commercial perfumes, but also for general qualitative profiling. ..
  9. Zoccali M, Schug K, Walsh P, Smuts J, Mondello L. Flow-modulated comprehensive two-dimensional gas chromatography combined with a vacuum ultraviolet detector for the analysis of complex mixtures. J Chromatogr A. 2017;1497:135-143 pubmed publisher
    ..Satisfactory results were obtained in terms of tailing factor (1.1), asymmetry factor (1.1), and similarity (average value 97%), for the FAMEs mixtures analysis. ..
  10. Sciarrone D, Giuffrida D, Rotondo A, Micalizzi G, Zoccali M, Pantò S, et al. Quali-quantitative characterization of the volatile constituents in Cordia verbenacea D.C. essential oil exploiting advanced chromatographic approaches and nuclear magnetic resonance analysis. J Chromatogr A. 2017;1524:246-253 pubmed publisher
  11. Cacciola F, Mangraviti D, Rigano F, Donato P, Dugo P, Mondello L, et al. Novel comprehensive multidimensional liquid chromatography approach for elucidation of the microbosphere of shikimate-producing Escherichia coli SP1.1/pKD15.071 strain. Anal Bioanal Chem. 2018;410:3473-3482 pubmed publisher
    ..The elucidation of the metabolic fraction of this bacterial strain might be of valid aid for improving, through genetic changes, the concentration and yield of shikimic acid synthesized from glucose. Graphical abstract. ..
  12. Mondello L, Beccaria M, Donato P, Cacciola F, Dugo G, Dugo P. Comprehensive two-dimensional liquid chromatography with evaporative light-scattering detection for the analysis of triacylglycerols in Borago officinalis. J Sep Sci. 2011;34:688-92 pubmed publisher
    ..The 2-D set-up, thanks to the complementary separation selectivity provided by the two columns, allowed to distribute 78 TAGs throughout the 2-D LC retention plane otherwise unachievable by 1-D LC...