Pietro Amedeo Modesti

Summary

Affiliation: University of Florence
Country: Italy

Publications

  1. ncbi request reprint ET(B) receptor in renal medulla is enhanced by local sodium during low salt intake
    Simone Vanni
    Clinica Medica e Cardiologia, University of Florence, Italy
    Hypertension 40:179-85. 2002
  2. ncbi request reprint Cardiovascular risk assessment in low-resource settings: a consensus document of the European Society of Hypertension Working Group on Hypertension and Cardiovascular Risk in Low Resource Settings
    Pietro A Modesti
    aDepartment of Clinical and Experimental Medicine, University of Florence, Florence bCentro Cardiologico Monzino, IRCCS, Milan, Italy cDepartment of Public Health, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands dUniversity of California, San Francisco, California, USA eINSERM UMR S1116, Université de Lorraine, Vandoeuvre les Nancy, Nancy, France fUniversity of Warwick, Warwick Medical School, and University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK gInstitut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Barcelona, Spain hSection of Metabolic Diseases and Diabetes, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy iMakerere University, Kampala, Uganda jThe Conway Institute, University College Dublin, Dublin, Ireland kBenedict Medical Center, Kampala, Uganda lClinica Medica II, University of Pavia, Pavia mInstitute of Clinical Physiology, CNR, Pisa nDepartment of Internal Medicine, University of Perugia, Perugia oIRCCS Istituto di Ricerche Farmacologiche Mario Negri, UK
    J Hypertens 32:951-60. 2014
  3. pmc Epidemiology of hypertension in Yemen: effects of urbanization and geographical area
    Pietro Amedeo Modesti
    Department of Clinical and Experimental Medicine, University of Florence, Azienda Ospedaliero Universitaria Careggi AOUC, Florence, Italy
    Hypertens Res 36:711-7. 2013
  4. pmc Relationship between hypertension, diabetes and proteinuria in rural and urban households in Yemen
    P A Modesti
    Department of Clinical and Experimental Medicine, University of Florence, Azienda Ospedaliero Universitaria Careggi AOUC, Florence, Italy
    J Hum Hypertens 27:572-9. 2013
  5. doi request reprint Season, temperature and blood pressure: a complex interaction
    Pietro Amedeo Modesti
    Dept of Clinical and Experimental Medicine, University of Florence, Florence, Italy Centre for Civil Protection and Risk Studies, University of Florence CESPRO, Florence, Italy Electronic address
    Eur J Intern Med 24:604-7. 2013
  6. doi request reprint Seasonal blood pressure changes: an independent relationship with temperature and daylight hours
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Hypertension 61:908-14. 2013
  7. doi request reprint The impact of fine-tuning of optical recognition system on database reliability
    P A Modesti
    Department of Critical Care Medicine, University of Florence, Florence, Italy
    Comput Biol Med 42:778-83. 2012
  8. ncbi request reprint Role of endothelin-1 in exposure to high altitude: Acute Mountain Sickness and Endothelin-1 (ACME-1) study
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Circulation 114:1410-6. 2006
  9. doi request reprint Index measured at an intermediate altitude to predict impending acute mountain sickness
    Pietro Amedeo Modesti
    Department of Medical and Surgical Critical Care, University of Florence, Italy
    Med Sci Sports Exerc 43:1811-8. 2011
  10. ncbi request reprint Ethnic differences in hypertension and blood pressure control. Issues for prevention strategies
    Pietro A Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134, Italy
    Saudi Med J 25:1160-4. 2004

Collaborators

Detail Information

Publications40

  1. ncbi request reprint ET(B) receptor in renal medulla is enhanced by local sodium during low salt intake
    Simone Vanni
    Clinica Medica e Cardiologia, University of Florence, Italy
    Hypertension 40:179-85. 2002
    ..The range of sodium concentrations that are physiologically present in vivo in the renal medulla selectively modulate type B receptor density and affinity...
  2. ncbi request reprint Cardiovascular risk assessment in low-resource settings: a consensus document of the European Society of Hypertension Working Group on Hypertension and Cardiovascular Risk in Low Resource Settings
    Pietro A Modesti
    aDepartment of Clinical and Experimental Medicine, University of Florence, Florence bCentro Cardiologico Monzino, IRCCS, Milan, Italy cDepartment of Public Health, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands dUniversity of California, San Francisco, California, USA eINSERM UMR S1116, Université de Lorraine, Vandoeuvre les Nancy, Nancy, France fUniversity of Warwick, Warwick Medical School, and University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK gInstitut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Barcelona, Spain hSection of Metabolic Diseases and Diabetes, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy iMakerere University, Kampala, Uganda jThe Conway Institute, University College Dublin, Dublin, Ireland kBenedict Medical Center, Kampala, Uganda lClinica Medica II, University of Pavia, Pavia mInstitute of Clinical Physiology, CNR, Pisa nDepartment of Internal Medicine, University of Perugia, Perugia oIRCCS Istituto di Ricerche Farmacologiche Mario Negri, UK
    J Hypertens 32:951-60. 2014
    ..This report summarizes current evidence and presents highlights of unmet needs. ..
  3. pmc Epidemiology of hypertension in Yemen: effects of urbanization and geographical area
    Pietro Amedeo Modesti
    Department of Clinical and Experimental Medicine, University of Florence, Azienda Ospedaliero Universitaria Careggi AOUC, Florence, Italy
    Hypertens Res 36:711-7. 2013
    ..98; 0.96-0.99). This large population study reveals that the highest burden of hypertension and kidney damage is detectable in remote areas of the country. ..
  4. pmc Relationship between hypertension, diabetes and proteinuria in rural and urban households in Yemen
    P A Modesti
    Department of Clinical and Experimental Medicine, University of Florence, Azienda Ospedaliero Universitaria Careggi AOUC, Florence, Italy
    J Hum Hypertens 27:572-9. 2013
    ..The approach of considering kidney damage as a consequence of hypertension and diabetes might limit the effectiveness of prevention strategies in low-income countries. ..
  5. doi request reprint Season, temperature and blood pressure: a complex interaction
    Pietro Amedeo Modesti
    Dept of Clinical and Experimental Medicine, University of Florence, Florence, Italy Centre for Civil Protection and Risk Studies, University of Florence CESPRO, Florence, Italy Electronic address
    Eur J Intern Med 24:604-7. 2013
    ....
  6. doi request reprint Seasonal blood pressure changes: an independent relationship with temperature and daylight hours
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Hypertension 61:908-14. 2013
    ..63; 0.37-0.90); and morning BP surge was negatively related to daylight hours (-0.54; -0.87 to -0.21). These results provide new evidence that PET and seasonality (daylight hours) are 2 independent predictors of ambulatory BP monitoring...
  7. doi request reprint The impact of fine-tuning of optical recognition system on database reliability
    P A Modesti
    Department of Critical Care Medicine, University of Florence, Florence, Italy
    Comput Biol Med 42:778-83. 2012
    ..65% to 0.05%. Fine-tuning should be introduced as a standard procedure while using optical reading systems...
  8. ncbi request reprint Role of endothelin-1 in exposure to high altitude: Acute Mountain Sickness and Endothelin-1 (ACME-1) study
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Circulation 114:1410-6. 2006
    ..The aim of the present study was to investigate the effects of ET-1 antagonism on pulmonary hypertension, renal water, and sodium balance under acute and prolonged exposure to high-altitude-associated hypoxia...
  9. doi request reprint Index measured at an intermediate altitude to predict impending acute mountain sickness
    Pietro Amedeo Modesti
    Department of Medical and Surgical Critical Care, University of Florence, Italy
    Med Sci Sports Exerc 43:1811-8. 2011
    ..The aim of the present study was to develop a predictive index, measured at an intermediate altitude, to predict the onset of AMS at a higher altitude...
  10. ncbi request reprint Ethnic differences in hypertension and blood pressure control. Issues for prevention strategies
    Pietro A Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134, Italy
    Saudi Med J 25:1160-4. 2004
    ....
  11. doi request reprint Impaired angiotensin II-extracellular signal-regulated kinase signaling in failing human ventricular myocytes
    Pietro Amedeo Modesti
    Department of Critical Care Medicine, University of Florence, Florence, Italy
    J Hypertens 26:2030-9. 2008
    ..Therefore, the altered growth factor production in failing myocytes is associated with a significant derangement in intracellular signaling...
  12. ncbi request reprint Weather-related changes in 24-hour blood pressure profile: effects of age and implications for hypertension management
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Florence, Italy
    Hypertension 47:155-61. 2006
    ..This may be because of a nocturnal BP escape from the effects of a lighter summertime drug regimen and may have important implications for seasonal modulation of antihypertensive treatment...
  13. doi request reprint Psychological predictors of the antihypertensive effects of music-guided slow breathing
    Pietro Amedeo Modesti
    Department of Critical Care Medicine, University of Florence, Italy
    J Hypertens 28:1097-103. 2010
    ..The possibility that daily sessions of music-guided slow breathing may reduce 24-h ambulatory blood pressure (ABP), and predictors of efficacy were explored in a randomized, placebo-controlled trial with parallel design...
  14. doi request reprint Response of serum proteome in patients undergoing infrarenal aortic aneurysm repair
    Pietro Amedeo Modesti
    Department of Critical Care Medicine and Don C Gnocchi Foundation, University of Florence, Viale Morgagni 85, Florence, Italy
    Anesthesiology 111:844-54. 2009
    ..A prospective,observational study was performed to define the complex plasma proteomic changes after AAA repair and to identify factor(s) that may affect myocardial function in uncomplicated procedures...
  15. ncbi request reprint Reduced expression of thyroid hormone receptors and beta-adrenergic receptors in human failing cardiomyocytes
    Pietro Amedeo Modesti
    Department of Critical Care Medicine, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Biochem Pharmacol 75:900-6. 2008
    ..These data reveal that in human heart failure the reduction of beta-adrenergic receptors is associated with reduced expression of both TRalpha1 and TRalpha2 isoforms of thyroid hormone receptors...
  16. ncbi request reprint Cardiac angiotensin II participates in coronary microvessel inflammation of unstable angina and strengthens the immunomediated component
    Gian Gastone Neri Serneri
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Circ Res 94:1630-7. 2004
    ..These results show that locally generated Ang II amplifies the immunomediated inflammatory process of coronary microvessels occurring in unstable angina...
  17. ncbi request reprint Different growth factor activation in the right and left ventricles in experimental volume overload
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Hypertension 43:101-8. 2004
    ..The left and right ventricles respond differently to aortocaval fistula, and local growth factor expression is closely related to the regional myocardial adaptation...
  18. ncbi request reprint Winter air-mass-based synoptic climatological approach and hospital admissions for myocardial infarction in Florence, Italy
    Marco Morabito
    Interdepartmental Center of Bioclimatology, University of Florence, P le delle Cascine 18, 50144 Florence, Italy
    Environ Res 102:52-60. 2006
    ..Increased risk of hospitalization was found even when specific 2-day air mass sequences occurred. These results represent an important step in identifying reliable linkages between weather and health...
  19. doi request reprint A proteomic approach to identify plasma proteins in patients with abdominal aortic aneurysm
    Tania Gamberi
    Department of Biochemical Sciences, University of Florence, Viale Morgagni 50, Florence, Italy
    Mol Biosyst 7:2855-62. 2011
    ....
  20. doi request reprint A biometeorological procedure for weather forecast to assess the optimal outdoor clothing insulation
    Marco Morabito
    Interdepartmental Centre of Bioclimatology, University of Florence, P le delle Cascine 18, 50144, Florence, Italy
    Eur J Appl Physiol 104:221-8. 2008
    ..The development of a daily operational procedure to forecast customized min_clo could provide useful information for the outdoor clothing fitting that might help to reduce the weather-related human health risk...
  21. ncbi request reprint Relationship between work-related accidents and hot weather conditions in Tuscany (central Italy)
    Marco Morabito
    Interdepartmental Centre of Bioclimatology, University of Florence, Piazzale delle Cascine 18, 50144 Florence, Italy
    Ind Health 44:458-64. 2006
    ..In conclusion, present findings might represent the first step for the development of a watch/warning system for workers that might be used by employers for planning work activities...
  22. doi request reprint Innovative approaches helpful to enhance knowledge on weather-related stroke events over a wide geographical area and a large population
    Marco Morabito
    Interdepartmental Centre of Bioclimatology, University of Florence, Piazzale delle Cascine 18, 50144 Firenze, Italy
    Stroke 42:593-600. 2011
    ....
  23. ncbi request reprint Relationships between weather and myocardial infarction: a biometeorological approach
    Marco Morabito
    Interdepartmental Centre of Bioclimatology University of Florence, Piazzale delle Cascine 18, 50144, Florence, Italy
    Int J Cardiol 105:288-93. 2005
    ..To calculate threshold values of weather discomfort which increase the risk of hospital admissions for myocardial infarction in winter and summer...
  24. ncbi request reprint Immunomediated and ischemia-independent inflammation of coronary microvessels in unstable angina
    Gian Gastone Neri Serneri
    Clinica Medica Generale e Cardiologia, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Circ Res 92:1359-66. 2003
    ..These results indicated that an acute immunomediated inflammatory reaction, essentially involving coronary microvessels, is demonstrable in UA patients...
  25. ncbi request reprint Hypertension and reduced renal function in an 83-year-old patient
    Andrea Ungar
    Unit of Geriatric Cardiology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
    Intern Emerg Med 1:40-8. 2006
  26. ncbi request reprint Adiponectin as a tissue regenerating hormone: more than a metabolic function
    Tania Fiaschi
    Dipartimento di Scienze Biomediche, Sperimentali e Cliniche, Universita degli Studi di Firenze, Viale Morgagni 50, 50134, Florence, Italy
    Cell Mol Life Sci 71:1917-25. 2014
    ..Overall, these recent findings contribute to highlight an intriguing function of adiponectin in addition to its well-recognized metabolic action. ..
  27. doi request reprint Environmental temperature and thermal indices: what is the most effective predictor of heat-related mortality in different geographical contexts?
    Marco Morabito
    Department of Agrifood Production and Environmental Sciences, University of Florence, Piazzale delle Cascine 18, 50144 Florence, Italy Interdepartmental Centre of Bioclimatology, University of Florence, Piazzale delle Cascine 18, 50144 Florence, Italy Center for Civil Protection and Risk Studies, University of Florence CESPRO, Viale Morgagni 48, 50134 Florence, Italy
    ScientificWorldJournal 2014:961750. 2014
    ..The use of direct multivariate indices, which also account for the extra effect of wind speed and/or solar radiation, revealed the best fitting with all-cause, very-elderly mortality attributable to heat stress...
  28. ncbi request reprint Impaired JAK2-induced activation of STAT3 in failing human myocytes
    Giulia Elisa Cambi
    Department of Critical Care Medicine, University of Florence, Largo Brambilla 3, 50134 Florence, Italy
    Mol Biosyst 8:2351-9. 2012
    ..27 fold) being abolished by p38 mitogen-activated protein kinase (MAPK) antagonism. The altered JAK2 induced STATs response in human failing cardiomyocytes may be of relevance for the progression of cardiac dysfunction in heart failure...
  29. doi request reprint Cardioplegia and angiotensin II receptor antagonists modulate signal transducers and activators of transcription activation in neonatal rat myocytes
    Gianluca Lucchese
    Division of Cardiac Surgery, University of Verona, Verona, Italy
    Artif Organs 35:1075-81. 2011
    ..AT1 receptor antagonist added to cardioplegia represents an additional modality for enhancing myocardial protection during cardiac surgery and could contribute to optimize the ischemia tolerance of the pediatric heart...
  30. doi request reprint 2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds
    Francesca Guidi
    Department of Chemistry, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Italy
    Mol Biosyst 8:985-93. 2012
    ..In conclusion, we performed a comprehensive analysis of proteins regulated by AuL12 and Au(2)Phen, providing a useful insight into their mechanisms of action...
  31. ncbi request reprint [Drug-induced nephropathy]
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia, Universita degli Studi di Firenze
    Ann Ital Med Int 18:126-35. 2003
    ..Many drugs can injure the kidneys, but they cause renal injury via only a few common mechanisms. The aim of the present review is to examine the main clinical presentations of drug-induced nephropathy...
  32. ncbi request reprint [Angiotensin-converting enzyme inhibitors :from vasoactive drugs to cardiovascular prevention tools]
    Pietro Amedeo Modesti
    Clinica Medica Generale e Cardiologia Università degli Studi Viale Morgagni, 85 50134 Firenze
    Ital Heart J Suppl 4:623-34. 2003
    ....
  33. doi request reprint New evidence
    Andrea Alberto Conti
    Department of Critical Care Medicine and Surgery, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence, Florence, Italy
    Intern Emerg Med 3:57-9. 2008
  34. doi request reprint A synoptic approach to weather conditions discloses a relationship with ambulatory blood pressure in hypertensives
    Marco Morabito
    Interdepartmental Centre of Bioclimatology, University of Florence, Florence, Italy
    Am J Hypertens 21:748-52. 2008
    ....
  35. ncbi request reprint Perioperative myocardial infarction in non-cardiac surgery. Pathophysiology and clinical implications
    Pietro Amedeo Modesti
    Clinical Medicine and Cardiology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
    Intern Emerg Med 1:177-86. 2006
    ..Therefore, the physician has to be aware of the key elements useful to calculate the perioperative cardiovascular risk, and of the medical preventive treatment or further interventions to adopt in patients candidate to surgery...
  36. doi request reprint Plasma protein carbonylation and physical exercise
    Francesca Guidi
    Department of Biochemical Sciences, University of Florence, Viale Morgagni, 50, 50134, Italy
    Mol Biosyst 7:640-50. 2011
    ..We also identified Serotransferrin and Fibrinogen whose carbonylation is reduced after exercise. These methods have allowed us to obtain an overview of plasma protein oxidation after physical exercise...
  37. doi request reprint Point-of-care testing of cholesterol and triglycerides for epidemiologic studies: evaluation of the multicare-in system
    Stefano Rapi
    Central Laboratory of Clinical Biochemistry, Careggi Hospital, and the Department of Critical Care Medicine, University of Florence, Florence, Italy
    Transl Res 153:71-6. 2009
    ..The characteristics of sensitivity and specificity as well as diagnostic accuracy make the POCT instrument useful for obtaining an accurate stratification of a study population...
  38. doi request reprint Office and 24-h ambulatory blood pressure control by treatment in general practice: the 'Monitoraggio della pressione ARteriosa nella medicina TErritoriale' study
    Augusto Zaninelli
    School of Medicine, University of Florence, Florence, Italy
    J Hypertens 28:910-7. 2010
    ..This is rarely done in general practice, and limited information is available on the consistency between the evaluations of the response to treatment provided by office measurement and by ABPM in this setting...
  39. ncbi request reprint Coronary artery calcium and the risk of infarction: a method in search for a role?
    Pietro Amedeo Modesti
    Ann Ital Med Int 20:I. 2005