Giuseppe Miserocchi

Summary

Affiliation: University of Milano-Bicocca
Country: Italy

Publications

  1. ncbi request reprint The pulmonary interstitium: an introductory review
    Giuseppe Miserocchi
    Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, Universita di Milano Bicocca, Via Cadore 48 20052 Monza, Italy
    Adv Exp Med Biol 536:141-5. 2003
  2. doi request reprint Pathophysiological alterations in oxygen delivery to the tissues
    Giuseppe Miserocchi
    Dipartimento di Medicina Sperimentale, Universita Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
    Transfus Apher Sci 45:291-7. 2011
  3. pmc Changes in the mechanical properties of the respiratory system during the development of interstitial lung edema
    Raffaele L Dellaca
    TBM Lab, Dipartimento di Bioingegneria, Politecnico di Milano University, Milano, Italy
    Respir Res 9:51. 2008
  4. doi request reprint Mechanisms controlling the volume of pleural fluid and extravascular lung water
    G Miserocchi
    Dipartimento di Medicina Sperimentale, Facolta di Medicina e Chirurgia, Universita di Milano Bicocca, Via Cadore 48, Monza, Italy
    Eur Respir Rev 18:244-52. 2009
  5. doi request reprint Respiratory mechanics and fluid dynamics after lung resection surgery
    Giuseppe Miserocchi
    Department of Experimental Medicine, Universita di Milano Bicocca, Via Cadore 48, Monza 20052, Italy
    Thorac Surg Clin 20:345-57. 2010
  6. ncbi request reprint Pulmonary interstitial pressure and tissue matrix structure in acute hypoxia
    G Miserocchi
    Department of Experimental and Environmental Medicine and Biotechnology, University of Milano Bicocca, 20052 Monza, Italy
    Am J Physiol Lung Cell Mol Physiol 280:L881-7. 2001
  7. ncbi request reprint Lung interstitial pressure and structure in acute hypoxia
    Giuseppe Miserocchi
    Department of Experimental Medicine, Universita Milano Bicocca, Monza, Italy
    Adv Exp Med Biol 618:141-57. 2007
  8. pmc Translocation pathways for inhaled asbestos fibers
    G Miserocchi
    Department of Experimental Medicine, University of Milano Bicocca, Via Cadore 48, 20052, Monza, Italy
    Environ Health 7:4. 2008
  9. ncbi request reprint Mechanisms behind inter-individual differences in lung diffusing capacity
    G Miserocchi
    Dipartimento di Medicina Sperimentale DIMS, Universita di Milano Bicocca, Via Cadore 48, 20052, Monza, Italy
    Eur J Appl Physiol 102:561-8. 2008
  10. pmc Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edema
    Laura Botto
    Department of Experimental, Environmental Medicine and Biotechnologies DIMESAB, University of Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
    Respir Res 7:7. 2006

Collaborators

Detail Information

Publications28

  1. ncbi request reprint The pulmonary interstitium: an introductory review
    Giuseppe Miserocchi
    Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, Universita di Milano Bicocca, Via Cadore 48 20052 Monza, Italy
    Adv Exp Med Biol 536:141-5. 2003
  2. doi request reprint Pathophysiological alterations in oxygen delivery to the tissues
    Giuseppe Miserocchi
    Dipartimento di Medicina Sperimentale, Universita Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
    Transfus Apher Sci 45:291-7. 2011
    ..The contribution of the various factors is modeled aiming to present a decisional flow chart for the functional evaluation of the efficiency of the oxygen transport system...
  3. pmc Changes in the mechanical properties of the respiratory system during the development of interstitial lung edema
    Raffaele L Dellaca
    TBM Lab, Dipartimento di Bioingegneria, Politecnico di Milano University, Milano, Italy
    Respir Res 9:51. 2008
    ..Our aim was to investigate the impact of the early stages of the development of interstitial edema on the mechanical properties of the respiratory system...
  4. doi request reprint Mechanisms controlling the volume of pleural fluid and extravascular lung water
    G Miserocchi
    Dipartimento di Medicina Sperimentale, Facolta di Medicina e Chirurgia, Universita di Milano Bicocca, Via Cadore 48, Monza, Italy
    Eur Respir Rev 18:244-52. 2009
    ....
  5. doi request reprint Respiratory mechanics and fluid dynamics after lung resection surgery
    Giuseppe Miserocchi
    Department of Experimental Medicine, Universita di Milano Bicocca, Via Cadore 48, Monza 20052, Italy
    Thorac Surg Clin 20:345-57. 2010
    ..New parameters are proposed to improve evaluation of respiratory function from pre- to the early postoperative period when most of the complications occur...
  6. ncbi request reprint Pulmonary interstitial pressure and tissue matrix structure in acute hypoxia
    G Miserocchi
    Department of Experimental and Environmental Medicine and Biotechnology, University of Milano Bicocca, 20052 Monza, Italy
    Am J Physiol Lung Cell Mol Physiol 280:L881-7. 2001
    ....
  7. ncbi request reprint Lung interstitial pressure and structure in acute hypoxia
    Giuseppe Miserocchi
    Department of Experimental Medicine, Universita Milano Bicocca, Monza, Italy
    Adv Exp Med Biol 618:141-57. 2007
    ..We provide evidence for a prompt lung cellular response to interstitial edema. We interpret this response as a fine mechanism to detect minor increases in extravascular water and to promote the reparative process...
  8. pmc Translocation pathways for inhaled asbestos fibers
    G Miserocchi
    Department of Experimental Medicine, University of Milano Bicocca, Via Cadore 48, 20052, Monza, Italy
    Environ Health 7:4. 2008
    ....
  9. ncbi request reprint Mechanisms behind inter-individual differences in lung diffusing capacity
    G Miserocchi
    Dipartimento di Medicina Sperimentale DIMS, Universita di Milano Bicocca, Via Cadore 48, 20052, Monza, Italy
    Eur J Appl Physiol 102:561-8. 2008
    ..The individual specificity in the lung volume dependence of V (c) and D (m) can be reasonably described by evaluating the V (c)/D (m) ratio at TLC and at approximately 40%TLC...
  10. pmc Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edema
    Laura Botto
    Department of Experimental, Environmental Medicine and Biotechnologies DIMESAB, University of Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
    Respir Res 7:7. 2006
    ..Based on these considerations, we aim to describe potential differences in the lung cellular response to the two types of edema...
  11. doi request reprint Hypoxia-induced modifications in plasma membranes and lipid microdomains in A549 cells and primary human alveolar cells
    Laura Botto
    Department of Experimental Medicine DIMS, University of Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
    J Cell Biochem 105:503-13. 2008
    ....
  12. ncbi request reprint Endothelial cells as early sensors of pulmonary interstitial edema
    Rossella Daffara
    Department of Experimental, Environmental Medicine and Biotechnology, University of Milano Bicocca, Monza 20052, Italy
    J Appl Physiol 97:1575-83. 2004
    ....
  13. ncbi request reprint Compositional changes in lipid microdomains of air-blood barrier plasma membranes in pulmonary interstitial edema
    Paola Palestini
    Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, Universita di Milano Bicocca, Via Cadore 48, 20052 Monza, MI Italy
    J Appl Physiol 95:1446-52. 2003
    ..Compositional changes in lipid microdomains represent a sign of cellular activation and suggest the potential role of mechanotransduction in response to developing interstitial edema...
  14. ncbi request reprint Gene expression analysis in interstitial lung edema induced by saline infusion
    Marta Sabbadini
    Department of Experimental, Environmental Medicine and Medical Biotechnology, University of Milano Bicocca, Via Cadore, 48, 20052 Monza, Italy
    Biochim Biophys Acta 1638:149-56. 2003
    ..Moreover, two MT1 genes were strongly up-regulated, data consistent with their role as protective molecules...
  15. doi request reprint Lung toxicity induced by intratracheal instillation of size-fractionated tire particles
    Paride Mantecca
    Department of Environmental Sciences, POLARIS Research Center, University of Milano Bicocca, 1 piazza della Scienza, Milan 20126, Italy
    Toxicol Lett 189:206-14. 2009
    ..We conclude that lung toxicity induced by TP10 was primarily due to macrophage-mediated inflammatory events, while toxicity induced by TP2.5 appeared to be related more closely to cytotoxicity...
  16. ncbi request reprint Cellular uptake of coumarin-6 as a model drug loaded in solid lipid nanoparticles
    I Rivolta
    Department of Experimental Medicine, University of Milano Bicocca, Monza, Italy
    J Physiol Pharmacol 62:45-53. 2011
    ....
  17. doi request reprint Interstitial pressure and lung oedema in chronic hypoxia
    I Rivolta
    Dept of Experimental Medicine, University of Milano Bicocca, Monza Italy
    Eur Respir J 37:943-9. 2011
    ....
  18. doi request reprint Assessment of dynamic mechanical properties of the respiratory system during high-frequency oscillatory ventilation*
    Raffaele L Dellaca
    1TBM Lab, Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano University, Milano, Italy 2Neonatal Intensive Care Unit, MBBM Foundation, Monza, Italy 3Department of Health Sciences, Universita di Milano Bicocca, Monza, Italy
    Crit Care Med 41:2502-11. 2013
    ....
  19. pmc Remodelling of membrane rafts expression in lung cells as an early sign of mechanotransduction-signalling in pulmonary edema
    Paola Palestini
    Department of Experimental Medicine, University of Milano Bicocca, 48 via Cadore, 20052 Monza, Italy
    J Lipids 2011:695369. 2011
    ....
  20. doi request reprint Inter-individual differences in control of alveolar capillary blood volume in exercise and hypoxia
    Manuela Bartesaghi
    Laboratory of Clinical Physiology and Exercise, Department of Health Sciences, University of Milano Bicocca, Via Cadore 48, 20900 Monza, Italy
    Respir Physiol Neurobiol 190:96-104. 2014
    ..The 4-fold increase in frequency dependence of respiratory resistance in Group2 in HA stems for greater proneness for lung water perturbation compared to Group 1. ..
  21. doi request reprint mRNA expression profile of selected oxygen sensing genes in the lung during recovery from chronic hypoxia
    Alice Panariti
    Department of Health Science, University of Milano Bicocca, Monza, Italy, 20900
    Biol Res 46:169-76. 2013
    ..In conclusion we showed the relevance of the decay in the mRNA and protein levels upon re-oxygenation in normoxia. We believe that this has to be considered in research studies dealing with recovery from hypoxia. ..
  22. doi request reprint A biophysical model of intracellular distribution and perinuclear accumulation of particulate matter
    Ilaria Rivolta
    Dipartimento di Medicina Sperimentale, Universita di Milano Bicocca, Monza, Italy
    Biophys Chem 158:134-40. 2011
    ....
  23. ncbi request reprint Composition, biophysical properties, and morphometry of plasma membranes in pulmonary interstitial edema
    Paola Palestini
    Department of Experimental, Environmental Medicine and Biotechnology, University of Milano Bicocca, Monza 20052, Italy
    Am J Physiol Lung Cell Mol Physiol 282:L1382-90. 2002
    ..Data suggest that mechanical stimuli elicited by a modest (approximately 4%) increase in extravascular water cause marked changes in plasma membranes that may be of relevance in signal transduction and endothelial cell activation...
  24. ncbi request reprint Non-linear dependence of interstitial fluid pressure on joint cavity pressure and implications for interstitial resistance in rabbit knee
    D Scott
    Department of Experimental, Environmental Medicine and Biotechnology, Faculty of Medicine and Surgery, Monza, Italy
    Acta Physiol Scand 179:93-101. 2003
    ..This study investigates whether subsynovial fluid pressure increases with intra-articular pressure, as this would reduce the estimated resistance estimate...
  25. doi request reprint Determinants of performance in 1,500-m runners
    Alessandra Ferri
    Department of Experimental Medicine, Laboratory of Clinical Physiology and Sport Medicine, University of Milano Bicocca, Monza, Italy
    Eur J Appl Physiol 112:3033-43. 2012
    ..We conclude that both the maximal capacity of muscle to extract O2 from the blood and the end-exercise blood lactate accumulation are important predictors of best performance in 1,500-m runners...
  26. ncbi request reprint Effect of gravity on chest wall mechanics
    D Bettinelli
    Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, Universita di Milano Bicocca, I 20052 Monza, Italy
    J Appl Physiol 92:709-16. 2002
    ..The data suggest that the chest wall does not behave as a linear system when exposed to changing gravity, as the effect depends on both chest wall volume and magnitude of G(z)...
  27. ncbi request reprint Development of lung edema: interstitial fluid dynamics and molecular structure
    G Miserocchi
    Department of Experimental and Environmental Medicine and Biotechnology, University of Milano-Bicocca, Milano, Italy
    News Physiol Sci 16:66-71. 2001
    ..Enzymatic degradation of proteoglycans disrupts the endothelial basal membrane and the matrix structure, triggering the development of pulmonary edema...
  28. ncbi request reprint Organic extract of tire debris causes localized damage in the plasma membrane of human lung epithelial cells
    E Beretta
    Department of Experimental Medicine, Via Cadore 48, 20052 Monza, University of Milano Bicocca, Italy
    Toxicol Lett 173:191-200. 2007
    ..The overall ultrastructural morphology of the plasma membrane of treated cells was not greatly modified, suggesting that organic extracts from tire debris cause focalized discontinuities on cell surfaces...