Research Topics
| Giuseppe MiserocchiSummaryAffiliation: University of Milano-Bicocca Country: Italy Publications
| Collaborators
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Detail Information
Publications
The pulmonary interstitium: an introductory reviewGiuseppe Miserocchi
Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, , Via Cadore 48 20052 Monza, Italy
Adv Exp Med Biol 536:141-5. 2003
Pathophysiological alterations in oxygen delivery to the tissuesGiuseppe Miserocchi
Dipartimento di Medicina Sperimentale, Universita Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
Transfus Apher Sci 45:291-7. 2011..The contribution of the various factors is modeled aiming to present a decisional flow chart for the functional evaluation of the efficiency of the oxygen transport system...
Changes in the mechanical properties of the respiratory system during the development of interstitial lung edemaRaffaele L Dellaca
TBM Lab, Dipartimento di Bioingegneria, Politecnico di Milano University, Milano, Italy
Respir Res 9:51. 2008..Our aim was to investigate the impact of the early stages of the development of interstitial edema on the mechanical properties of the respiratory system...- Pulmonary interstitial pressure and tissue matrix structure in acute hypoxiaG Miserocchi
Department of Experimental and Environmental Medicine and Biotechnology, University of Milano Bicocca, 20052 Monza, Italy
Am J Physiol Lung Cell Mol Physiol 280:L881-7. 2001.... - Mechanisms controlling the volume of pleural fluid and extravascular lung waterG Miserocchi
Dipartimento di Medicina Sperimentale, Facolta di Medicina e Chirurgia, Universita di Milano Bicocca, Via Cadore 48, Monza, Italy
Eur Respir Rev 18:244-52. 2009.... - Respiratory mechanics and fluid dynamics after lung resection surgeryGiuseppe Miserocchi
Department of Experimental Medicine, Universita di Milano Bicocca, Via Cadore 48, Monza 20052, Italy
Thorac Surg Clin 20:345-57. 2010..New parameters are proposed to improve evaluation of respiratory function from pre- to the early postoperative period when most of the complications occur... - Lung interstitial pressure and structure in acute hypoxiaGiuseppe Miserocchi
Department of Experimental Medicine, Universita Milano Bicocca, Monza, Italy
Adv Exp Med Biol 618:141-57. 2007..We provide evidence for a prompt lung cellular response to interstitial edema. We interpret this response as a fine mechanism to detect minor increases in extravascular water and to promote the reparative process... - Translocation pathways for inhaled asbestos fibersG Miserocchi
Department of Experimental Medicine, University of Milano Bicocca, Via Cadore 48, 20052, Monza, Italy
Environ Health 7:4. 2008.... - Mechanisms behind inter-individual differences in lung diffusing capacityG Miserocchi
Dipartimento di Medicina Sperimentale DIMS, Universita di Milano Bicocca, Via Cadore 48, 20052, Monza, Italy
Eur J Appl Physiol 102:561-8. 2008..The individual specificity in the lung volume dependence of V (c) and D (m) can be reasonably described by evaluating the V (c)/D (m) ratio at TLC and at approximately 40%TLC... - Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edemaLaura Botto
Department of Experimental, Environmental Medicine and Biotechnologies DIMESAB, University of Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
Respir Res 7:7. 2006..Based on these considerations, we aim to describe potential differences in the lung cellular response to the two types of edema... - Hypoxia-induced modifications in plasma membranes and lipid microdomains in A549 cells and primary human alveolar cellsLaura Botto
Department of Experimental Medicine DIMS, University of Milano Bicocca, Via Cadore 48, 20052 Monza, Italy
J Cell Biochem 105:503-13. 2008.... - Endothelial cells as early sensors of pulmonary interstitial edemaRossella Daffara
Department of Experimental, Environmental Medicine and Biotechnology, University of Milano-Bicocca, Monza 20052, Italy
J Appl Physiol 97:1575-83. 2004.... - Compositional changes in lipid microdomains of air-blood barrier plasma membranes in pulmonary interstitial edemaPaola Palestini
Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, , Via Cadore 48, 20052 Monza, MI Italy
J Appl Physiol 95:1446-52. 2003..Compositional changes in lipid microdomains represent a sign of cellular activation and suggest the potential role of mechanotransduction in response to developing interstitial edema... - Lung toxicity induced by intratracheal instillation of size-fractionated tire particlesParide Mantecca
Department of Environmental Sciences, POLARIS Research Center, University of Milano Bicocca, 1 piazza della Scienza, Milan 20126, Italy
Toxicol Lett 189:206-14. 2009..We conclude that lung toxicity induced by TP10 was primarily due to macrophage-mediated inflammatory events, while toxicity induced by TP2.5 appeared to be related more closely to cytotoxicity... - Gene expression analysis in interstitial lung edema induced by saline infusionMarta Sabbadini
Department of Experimental, Environmental Medicine and Medical Biotechnology, University of Milano-Bicocca, Via Cadore, 48, 20052 Monza, Italy
Biochim Biophys Acta 1638:149-56. 2003..Moreover, two MT1 genes were strongly up-regulated, data consistent with their role as protective molecules... - Interstitial pressure and lung oedema in chronic hypoxiaI Rivolta
Dept of Experimental Medicine, University of Milano Bicocca, Monza Italy
Eur Respir J 37:943-9. 2011.... - Cellular uptake of coumarin-6 as a model drug loaded in solid lipid nanoparticlesI Rivolta
Department of Experimental Medicine, University of Milano Bicocca, Monza, Italy
J Physiol Pharmacol 62:45-53. 2011.... - Remodelling of membrane rafts expression in lung cells as an early sign of mechanotransduction-signalling in pulmonary edemaPaola Palestini
Department of Experimental Medicine, University of Milano Bicocca, 48 via Cadore, 20052 Monza, Italy
J Lipids 2011:695369. 2011.... - A biophysical model of intracellular distribution and perinuclear accumulation of particulate matterIlaria Rivolta
Dipartimento di Medicina Sperimentale, Universita di Milano Bicocca, Monza, Italy
Biophys Chem 158:134-40. 2011.... - Composition, biophysical properties, and morphometry of plasma membranes in pulmonary interstitial edemaPaola Palestini
Department of Experimental, Environmental Medicine and Biotechnology, University of Milano-Bicocca, Monza 20052, Italy
Am J Physiol Lung Cell Mol Physiol 282:L1382-90. 2002..Data suggest that mechanical stimuli elicited by a modest (approximately 4%) increase in extravascular water cause marked changes in plasma membranes that may be of relevance in signal transduction and endothelial cell activation... - Non-linear dependence of interstitial fluid pressure on joint cavity pressure and implications for interstitial resistance in rabbit kneeD Scott
Department of Experimental, Environmental Medicine and Biotechnology, Faculty of Medicine and Surgery, Monza, Italy
Acta Physiol Scand 179:93-101. 2003..5x by dPj/dQs. This narrows but does not eliminate the gap between analysed glycosaminoglycan concentration, 4 mg ml(-1), and the net interstitial biopolymer concentration of 11.5 mg ml(-1) needed to generate the resistance... - Determinants of performance in 1,500-m runnersAlessandra Ferri
Department of Experimental Medicine, Laboratory of Clinical Physiology and Sport Medicine, University of Milano Bicocca, Monza, Italy
Eur J Appl Physiol 112:3033-43. 2012..We conclude that both the maximal capacity of muscle to extract O2 from the blood and the end-exercise blood lactate accumulation are important predictors of best performance in 1,500-m runners... - Development of lung edema: interstitial fluid dynamics and molecular structureG Miserocchi
Department of Experimental and Environmental Medicine and Biotechnology, University of Milano-Bicocca, Milano, Italy
News Physiol Sci 16:66-71. 2001..Enzymatic degradation of proteoglycans disrupts the endothelial basal membrane and the matrix structure, triggering the development of pulmonary edema... - Effect of gravity on chest wall mechanicsD Bettinelli
Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, , I-20052 Monza, Italy
J Appl Physiol 92:709-16. 2002..The data suggest that the chest wall does not behave as a linear system when exposed to changing gravity, as the effect depends on both chest wall volume and magnitude of G(z)... - Organic extract of tire debris causes localized damage in the plasma membrane of human lung epithelial cellsE Beretta
Department of Experimental Medicine, Via Cadore 48, 20052 Monza, University of Milano Bicocca, Italy
Toxicol Lett 173:191-200. 2007..The overall ultrastructural morphology of the plasma membrane of treated cells was not greatly modified, suggesting that organic extracts from tire debris cause focalized discontinuities on cell surfaces...