Affiliation: University of Florence
- Incidence and prognostic significance of occult tumor cells in lymph nodes from patients with stage IIA colorectal carcinomaLuca Messerini
Department of Human Pathology and Oncology, University of Florence Medical School, Florence 50134, Italy
Hum Pathol 37:1259-67. 2006..The detection of immunostained tumor cells in the LNs of patients with stage IIA CRC occurs relatively frequently but has no significant effect on prognosis...
- h-caldesmon, calretinin, estrogen receptor, and Ber-EP4: a useful combination of immunohistochemical markers for differentiating epithelioid peritoneal mesothelioma from serous papillary carcinoma of the ovaryCamilla E Comin
Department of Human Pathology and Oncology, University of Florence, Florence, Italy
Am J Surg Pathol 31:1139-48. 2007....
- Lymph node recovery from colorectal tumor specimens: recommendation for a minimum number of lymph nodes to be examinedFabio Cianchi
Dipartimento di Area Critica Medico Chirurgica, Sez Clinica Chirurgica e Terapia Chirurgica, University of Florence, School of Medicine, Viale Morgagni 85, 50134 Florence, Italy
World J Surg 26:384-9. 2002..Our results suggest that harvesting and examining a minimum of nine lymph nodes per surgical specimen may be sufficient for reliable staging of lymph node-negative tumors...
- Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cellsFabio Cianchi
Dipartimento di Area Critica Medico Chirurgica Medical School, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
Mol Cancer Ther 5:2716-26. 2006..In conclusion, our study showed that inhibition of 5-LOX by MK886 could augment the antitumor activity of celecoxib in human colorectal cancer...
- Multiple effects of somatostatin analogs verified in three cases of metastasized neuroendocrine tumors of the gastroenteropancreatic systemGiancarlo Biliotti
Unit of Surgery, University of Florence, Italy
Tumori 92:170-4. 2006..In this study the authors, based on their own experience, evaluate the effectiveness of SST analogs in treating GEP endocrine tumors...
- Pathologic determinants of survival after resection of T3N0 (Stage IIA) colorectal cancer: proposal for a new prognostic modelFabio Cianchi
Department of General Surgery, University of Florence, Florence, Italy
Dis Colon Rectum 50:1332-41. 2007..This study was designed to evaluate the prognostic impact of a wide spectrum of pathologic parameters in a consecutive series of homogenously treated and well-characterized patients with Stage IIA (T3N0M0) colorectal cancer...
- Clear cell sarcoma of the ileum: report of a case and review of literatureCamilla E Comin
Dipartimento di Patologia Umana ed Oncologia, Universita degli Studi di Firenze, V le Morgagni, 85, 50134 Firenze, Italy
Virchows Arch 451:839-45. 2007....
- The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancerFabio Cianchi
Department of General Surgery, Medical School, University of Florence, Italy
Clin Cancer Res 11:6807-15. 2005..We attempted to establish whether the possible involvement of histidine decarboxylase and histamine in colorectal carcinogenesis might be mediated by the activation of the cyclooxygenase-2 (COX-2) pathway...
- Solitary necrotic nodules of the liver: cross-sectional imaging findings and follow-up in nine patientsStefano Colagrande
Department of Clinical Physiopathology, Section of Radiodiagnostics, University of Florence, Viale Morgagni 85, Azienda Ospedaliero Universitaria Careggi, 50134 Florence, Italy
AJR Am J Roentgenol 191:1122-8. 2008....
- Liver angiogenesis as a risk factor for hepatocellular carcinoma development in hepatitis C virus cirrhotic patientsRoberto Mazzanti
Department of Internal Medicine, University of Florence School of Medicine, Viale GB Morgagni 85, I 50134 Firenze, Italy
World J Gastroenterol 13:5009-14. 2007..To evaluate the predictive value of hepatocyte proliferation and hepatic angiogenesis for the occurrence of Hepatocellular carcinoma (HCC) in hepatitis C virus (HCV) cirrhotic patients...
- Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancerFabio Cianchi
Department of General Surgery, Medical School, University of Florence, Florence, Italy
Clin Cancer Res 10:2694-704. 2004..We aimed at evaluating the possible interaction between the nitric oxide and COX-2 pathways, and its effect on promoting tumor angiogenesis...
- Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesisFabio Cianchi
Department of General Surgery, Medical School, University of Florence, Florence, Italy
Am J Pathol 162:793-801. 2003..Western and Northern blot analyses confirmed the up-regulation of the iNOS protein and gene in the tumor specimens as compared with normal mucosa. NO seems to play a role in colorectal cancer growth by promoting tumor angiogenesis...
- Tumor angiogenesis in lymph node-negative rectal cancer: correlation with clinicopathological parameters and prognosisFabio Cianchi
Department of General Surgery, University of Florence, Italy
Ann Surg Oncol 9:20-6. 2002..We retrospectively analyzed the value of microvessel count in predicting the clinical outcome of stage I and II (Dukes A and B) rectal cancer patients...
- h-Caldesmon, a useful positive marker in the diagnosis of pleural malignant mesothelioma, epithelioid typeCamilla E Comin
Department of Human Pathology and Oncology, University of Florence Medical School, Florence, Italy
Am J Surg Pathol 30:463-9. 2006..We conclude that h-caldesmon is a highly sensitive and specific marker and suggest its inclusion in the immunohistochemical panel for the differential diagnosis of epithelioid mesothelioma versus lung adenocarcinoma...
- Analysis of gene expression profiles reveals novel correlations with the clinical course of colorectal cancerDuccio Cavalieri
Department of Pharmacology, University of Florence, Florence, Italy
Oncol Res 16:535-48. 2007..In this set of patients the Cox Proportional Hazard Model analysis demonstrated a significant association between increased patient survival and low expression of ITGB2 (p = 0.011) and NPR1 (p = 0.023) genes...
- Adjuvant chemotherapy in completely resected gastric cancer: a randomized phase III trial conducted by GOIRCFrancesco Di Costanzo
Unit of Medical Oncology, Azienda Ospedaliero Universitaria Careggi, Viale Pieraccini 17, 50139 Florence, Italy
J Natl Cancer Inst 100:388-98. 2008..Complete surgical resection of gastric cancer is potentially curative, but long-term survival is poor...
- NF2 expression levels of gastrointestinal stromal tumors: a quantitative real-time PCR studyAntonio Taddei
Department of Surgical Pathology, University of Florence, School of Medicine, Florence, Italy
Tumori 94:551-5. 2008..NF2 gene mRNA expression was assessed in fresh tissue of stomach from 5 consecutive patients. We detected no alterations in NF2 gene expression in the quantitative analyses of the 5 tumors...
- KI-67 antigen expression predicts survival and correlates with histologic subtype in the WHO classification of thymic epithelial tumorsCamilla E Comin
Dipartimento di Patologia Umana ed Oncologia, Universita degli Studi di Firenze, Italy
Int J Surg Pathol 12:395-400. 2004....
- herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cellsElena Lastraioli
Department of Experimental Pathology and Oncology, University of Firenze, Firenze, Italy
Cancer Res 64:606-11. 2004....
- Quantitative evaluation of somatostatin receptor subtype 2 expression in sporadic colorectal tumor and in the corresponding normal mucosaClaudia Casini Raggi
Clinical Biochemistry Unit, Department of Clinical Physiopathology, University of Florence, Pieraccini 6, 50139 Florence, Italy
Clin Cancer Res 8:419-27. 2002..In a limited number of patients, these results were compared with those obtained by in situ hybridization (n = 26) and by in vivo imaging with (111)In-pentetreotide (n = 17)...
- hERG1 channels in human esophagus: evidence for their aberrant expression in the malignant progression of Barrett's esophagusElena Lastraioli
Dipartimento di Patologia e Oncologia Sperimentali, University of Florence, Florence, Italy
J Cell Physiol 209:398-404. 2006..Data here reported, support the hypothesis that hERG1 expression marks an early step of the progression of normality to cancer in the human esophagus through a metaplastic and dysplastic stage...
- Pegylated interferon alfa-2b plus ribavirin in the retreatment of interferon-ribavirin nonresponder patientsGloria Taliani
Department of Infectious and Tropical Diseases, La Sapienza University, Rome, Italy
Gastroenterology 130:1098-106. 2006..Treatment up to 48 weeks also in patients who have failed to clear hepatitis C virus (HCV) RNA by week 24 was also evaluated...
- Correlations between phenotype and microsatellite instability in HNPCC: implications for genetic testingRaffaele Palmirotta
Department of Oncology and Neurosciences, University Gabriele D Annunzio, Chieti, Italy
Fam Cancer 3:117-21. 2004..These families probably carry mutations in other genes that may or may not be related to MMR. Additional studies are necessary to clarify the molecular basis for HNPCC in families with MSS tumors...
- Intrabiliary metastasis from rectal cancer mimicking peripheral papillary-type cholangiocarcinomaStefano Colagrande
J Hepatol 41:172-4. 2004
- Long-term outcome of renal transplantation from older donorsMaria Rosaria Raspollini
N Engl J Med 354:2071-4; author reply 2071-4. 2006