A Merighi

Summary

Affiliation: University of Turin
Country: Italy

Publications

  1. ncbi request reprint Costorage and coexistence of neuropeptides in the mammalian CNS
    A Merighi
    Department of Veterinary Morphophysiology, Rita Levi Montalcini Center for Brain Repair, University of Torino, UE, Italy
    Prog Neurobiol 66:161-90. 2002
  2. ncbi request reprint Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse
    Francesco Ferrini
    Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    Pain 129:195-209. 2007
  3. doi request reprint The gastrointestinal hormone ghrelin modulates inhibitory neurotransmission in deep laminae of mouse spinal cord dorsal horn
    Angela M Vergnano
    Department of Veterinary Morphophysiology, University of Turin, Via Leonardo da Vinci 44, 10095 Grugliasco Torino, Italy
    Endocrinology 149:2306-12. 2008
  4. doi request reprint Neuromodulatory function of neuropeptides in the normal CNS
    Adalberto Merighi
    University of Turin, Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, 10095 Grugliasco, Torino, Italy
    J Chem Neuroanat 42:276-87. 2011
  5. doi request reprint BDNF as a pain modulator
    Adalberto Merighi
    Dipartimento di Morfofisiologia Veterinaria, University of Turin, Turin, Italy
    Prog Neurobiol 85:297-317. 2008
  6. doi request reprint Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord
    Adalberto Merighi
    Dipartimento di Morfofisiologia Veterinaria, Universita di Torino, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    Dev Neurobiol 68:457-75. 2008
  7. ncbi request reprint Neurotrophins in spinal cord nociceptive pathways
    Adalberto Merighi
    Department of Veterinary Morphophysiology, Rita Levi Montalcini Center for Brain Repair, Via Leonardo da Vinci 44, 10095 Grugliasco, Turin, Italy
    Prog Brain Res 146:291-321. 2004
  8. doi request reprint Posttranslational regulation of BCL2 levels in cerebellar granule cells: A mechanism of neuronal survival
    Laura Lossi
    Dipartimento di Morfofisiologia Veterinaria, Universita degli Studi di Torino, Italy
    Dev Neurobiol 69:855-70. 2009
  9. doi request reprint Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
    Laura Lossi
    Dipartimento di Morfofisiologia Veterinaria, University of Turin, Turin, Italy
    Prog Neurobiol 88:221-45. 2009
  10. doi request reprint Autophagy regulates the post-translational cleavage of BCL-2 and promotes neuronal survival
    Laura Lossi
    Dipartimento di Morfofisiologia Veterinaria e Istituto Nazionale di Neuroscienze, Universita degli Studi di Torino, Grugliasco, Turin, Italy
    ScientificWorldJournal 10:924-9. 2010

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Costorage and coexistence of neuropeptides in the mammalian CNS
    A Merighi
    Department of Veterinary Morphophysiology, Rita Levi Montalcini Center for Brain Repair, University of Torino, UE, Italy
    Prog Neurobiol 66:161-90. 2002
    ..Finally, a brief account is given on the presence of neuropeptides in glial cells...
  2. ncbi request reprint Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse
    Francesco Ferrini
    Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    Pain 129:195-209. 2007
    ..The peptide then excites inhibitory neurons in laminae I, III and IV, leading to an increased release of GABA/glycine in lamina II via a parallel alternative pathway to glutamate...
  3. doi request reprint The gastrointestinal hormone ghrelin modulates inhibitory neurotransmission in deep laminae of mouse spinal cord dorsal horn
    Angela M Vergnano
    Department of Veterinary Morphophysiology, University of Turin, Via Leonardo da Vinci 44, 10095 Grugliasco Torino, Italy
    Endocrinology 149:2306-12. 2008
    ....
  4. doi request reprint Neuromodulatory function of neuropeptides in the normal CNS
    Adalberto Merighi
    University of Turin, Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, 10095 Grugliasco, Torino, Italy
    J Chem Neuroanat 42:276-87. 2011
    ....
  5. doi request reprint BDNF as a pain modulator
    Adalberto Merighi
    Dipartimento di Morfofisiologia Veterinaria, University of Turin, Turin, Italy
    Prog Neurobiol 85:297-317. 2008
    ..Recent studies have unraveled some of the neuronal circuitries and mechanisms involved, highlighting the key role of synaptic glomeruli in lamina II as the main sites for such a modulation...
  6. doi request reprint Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord
    Adalberto Merighi
    Dipartimento di Morfofisiologia Veterinaria, Universita di Torino, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    Dev Neurobiol 68:457-75. 2008
    ..Implications of this finding are discussed considering that BDNF can be released by these same terminals and microglia, a fraction of which (as shown here) contains BDNF also in unactivated state...
  7. ncbi request reprint Neurotrophins in spinal cord nociceptive pathways
    Adalberto Merighi
    Department of Veterinary Morphophysiology, Rita Levi Montalcini Center for Brain Repair, Via Leonardo da Vinci 44, 10095 Grugliasco, Turin, Italy
    Prog Brain Res 146:291-321. 2004
    ....
  8. doi request reprint Posttranslational regulation of BCL2 levels in cerebellar granule cells: A mechanism of neuronal survival
    Laura Lossi
    Dipartimento di Morfofisiologia Veterinaria, Universita degli Studi di Torino, Italy
    Dev Neurobiol 69:855-70. 2009
    ..This study identifies novel mechanisms of neuroprotection in immature and mature CGCs involving the posttranslational regulation of BCL2...
  9. doi request reprint Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
    Laura Lossi
    Dipartimento di Morfofisiologia Veterinaria, University of Turin, Turin, Italy
    Prog Neurobiol 88:221-45. 2009
    ..e. the cortical, hippocampal, cerebellar and retinal slices...
  10. doi request reprint Autophagy regulates the post-translational cleavage of BCL-2 and promotes neuronal survival
    Laura Lossi
    Dipartimento di Morfofisiologia Veterinaria e Istituto Nazionale di Neuroscienze, Universita degli Studi di Torino, Grugliasco, Turin, Italy
    ScientificWorldJournal 10:924-9. 2010
    ..The more general significance of these findings is supported by a very recent study Niemann-Pick transgenic mice...
  11. doi request reprint Modulation of inhibitory neurotransmission by the vanilloid receptor type 1 (TRPV1) in organotypically cultured mouse substantia gelatinosa neurons
    Francesco Ferrini
    Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    Pain 150:128-40. 2010
    ..These data show that TRPV1 modulates inhibitory neurotransmission in cultured substantia gelatinosa neurons, and suggest that endogenous agonists can activate the spinal receptors in vivo...
  12. ncbi request reprint Costorage of BDNF and neuropeptides within individual dense-core vesicles in central and peripheral neurons
    C Salio
    Department of Veterinary Morphophysiology, University of Turin, Turin, Italy
    Dev Neurobiol 67:326-38. 2007
    ..It provides structural bases for differential release upon stimulation, and has important implications for understanding BDNF transmitter function...
  13. ncbi request reprint Apoptosis in the mammalian CNS: Lessons from animal models
    L Lossi
    Dipartimento di Morfofisiologia Veterinaria, University of Torino, Via Leonardo da Vinci 44, I 10095 Grugliasco, Italy
    Vet J 170:52-66. 2005
    ..A thorough analysis of naturally occurring neuronal death in vivo will offer a basis for parallel and future studies involving secondary neuronal loss such as those in neurodegenerative disorders, trauma or ischaemia...
  14. ncbi request reprint Synapse-independent and synapse-dependent apoptosis of cerebellar granule cells in postnatal rabbits occur at two subsequent but partly overlapping developmental stages
    L Lossi
    Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, I 10095 Grugliasco, Italy
    Neuroscience 112:509-23. 2002
    ..The less tumultuous cell death of post-mitotic granule cells in the internal granular layer appears to be linked to the formation of the mature synaptic circuitry of the developing cerebellar cortex...
  15. ncbi request reprint In vivo cellular and molecular mechanisms of neuronal apoptosis in the mammalian CNS
    L Lossi
    Department of Veterinary Morphophysiology, University of Torino, Via Leonardo da Vinci 44, I 10095 TO, Grugliasco, Italy
    Prog Neurobiol 69:287-312. 2003
    ....
  16. ncbi request reprint Ultrastructural evidence for a pre- and postsynaptic localization of full-length trkB receptors in substantia gelatinosa (lamina II) of rat and mouse spinal cord
    Chiara Salio
    Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    Eur J Neurosci 22:1951-66. 2005
    ....
  17. pmc Ghrelin in central neurons
    F Ferrini
    Dipartimento di Morfofisiologia Veterinaria, , Via Leonardo da Vinci 44, 10095, Grugliasco
    Curr Neuropharmacol 7:37-49. 2009
    ..This paper gives an overview on the distribution of ghrelin and its receptor across the CNS and critically analyses the data available so far as regarding the effects of ghrelin on central neurotransmission...
  18. ncbi request reprint Neuropeptides as synaptic transmitters
    Chiara Salio
    Dipartimento di Morfofisiologia Veterinaria and Rita Levi Montalcini Center for Brain Repair, Via Leonardo da Vinci 44, 10095, Grugliasco TO, Italy
    Cell Tissue Res 326:583-98. 2006
    ..Thus, the subcellular site(s) of storage and sorting mechanisms into different neuronal compartments are crucial to the mode of release and the function of neuropeptides as neuronal messengers...
  19. ncbi request reprint Molecular morphology of neuronal apoptosis: analysis of caspase 3 activation during postnatal development of mouse cerebellar cortex
    Laura Lossi
    Department of Veterinary Morphophysiology, Rita Levi Montalcini Center for Brain Repair, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    J Mol Histol 35:621-9. 2004
    ....
  20. ncbi request reprint In vivo analysis reveals different apoptotic pathways in pre- and postmigratory cerebellar granule cells of rabbit
    Laura Lossi
    Department of Veterinary Morphophysiology, University of Turin, Via Leonardo da Vinci 44, 10095 Grugliasco TO Italy, UE
    J Neurobiol 60:437-52. 2004
    ..We conclude that NOND of premigratory CGCs is linked to activation of DNA checkpoint and alteration of normal cell cycle, whereas in postmigratory CGCs apoptosis is, more classically, dependent upon caspase 3 activation...
  21. ncbi request reprint Transient expression of secretin in serotoninergic neurons of mouse brain during development
    Laura Lossi
    Department of Veterinary Morphophysiology, University of Turin, Via Leonardo da Vinci 44, 10095 Grugliasco, Torino, Italy
    Eur J Neurosci 20:3259-69. 2004
    ..In addition our data suggest a trophic role for secretin on neurons known to be involved in multiple superior functions in the normal brain, and lost in neurodegenerative disorders...
  22. ncbi request reprint NK1 receptor activation leads to enhancement of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse
    Angela Maria Vergnano
    Department of Veterinary Morphophysiology, Via Leonardo da Vinci 44, 10095 Grugliasco, Italy
    Pain 112:37-47. 2004
    ....
  23. ncbi request reprint BDNF-mediated modulation of GABA and glycine release in dorsal horn lamina II from postnatal rats
    Rita Bardoni
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Dev Neurobiol 67:960-75. 2007
    ..Our results thus describe a yet uncharacterized effect of BDNF in lamina II, giving further strength to the notion that the neurotrophin plays an important role in pain neurotransmission...