Michele Menotta

Summary

Affiliation: University of Urbino
Country: Italy

Publications

  1. pmc Dexamethasone partially rescues ataxia telangiectasia-mutated (ATM) deficiency in ataxia telangiectasia by promoting a shortened protein variant retaining kinase activity
    Michele Menotta
    Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy
    J Biol Chem 287:41352-63. 2012
  2. ncbi Label-free quantification of activated NF-kappaB in biological samples by atomic force microscopy
    Michele Menotta
    Department of Biomolecular Sciences, University of Urbino Carlo Bo Via Saffi 2 61029 Urbino, PU, Italy
    Biosens Bioelectron 25:2490-6. 2010
  3. pmc Molecular and functional characterization of a Rho GDP dissociation inhibitor in the filamentous fungus Tuber borchii
    Michele Menotta
    Center for Biochemistry, Medical Faculty, University of Cologne, Joseph Stelzmann Str, 52, 50931 Cologne, Germany
    BMC Microbiol 8:57. 2008
  4. ncbi Oxidized ultrashort nanotubes as carbon scaffolds for the construction of cell-penetrating NF-kappaB decoy molecules
    Rita Crinelli
    Department of Biomolecular Sciences, Biochemistry and Molecular Biology Section, University of Urbino Carlo Bo, 61029 Urbino, PU, Italy
    ACS Nano 4:2791-803. 2010
  5. doi Geographical traceability of Italian white truffle (Tuber magnatum Pico) by the analysis of volatile organic compounds
    Anna Maria Gioacchini
    Istituto di Ricerca sull Attività Motoria, Via I Maggetti 26, Universita degli Studi di Urbino Carlo Bo, 61029 Urbino, Italy
    Rapid Commun Mass Spectrom 22:3147-53. 2008
  6. doi Ubiquitin over-expression promotes E6AP autodegradation and reactivation of the p53/MDM2 pathway in HeLa cells
    Rita Crinelli
    Istituto di Chimica Biologica G Fornaini, Universita degli Studi di Urbino Carlo Bo, Via Saffi, 2, 61029 Urbino, PU, Italy
    Mol Cell Biochem 318:129-45. 2008
  7. doi Binding force measurement of NF-κB-ODNs interaction: an AFM based decoy and drug testing tool
    Michele Menotta
    Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via Saffi 2, 61029 Urbino PU, Italy
    Biosens Bioelectron 28:158-65. 2011
  8. ncbi Forward subtractive libraries containing genes transactivated by dexamethasone in ataxia-telangiectasia lymphoblastoid cells
    Sara Biagiotti
    Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via Saffi 2, 61029, Urbino, PU, Italy
    Mol Cell Biochem 392:13-30. 2014
  9. ncbi Hexose uptake in the plant symbiotic ascomycete Tuber borchii Vittadini: biochemical features and expression pattern of the transporter TBHXT1
    Emanuela Polidori
    Istituto di Ricerca sull Attività Motoria, Universita degli Studi di Urbino Carlo Bo, Via I Maggetti 26, 61029 Urbino, Italy
    Fungal Genet Biol 44:187-98. 2007
  10. ncbi Identification and characterization of the Tuber borchii D-mannitol dehydrogenase which defines a new subfamily within the polyol-specific medium chain dehydrogenases
    Paola Ceccaroli
    Istituto di Chimica Biologica Giorgio Fornaini, Universita degli Studi di Urbino Carlo Bo, Via A Saffi 2, 61029, Urbino PU, Italy
    Fungal Genet Biol 44:965-78. 2007

Collaborators

Detail Information

Publications15

  1. pmc Dexamethasone partially rescues ataxia telangiectasia-mutated (ATM) deficiency in ataxia telangiectasia by promoting a shortened protein variant retaining kinase activity
    Michele Menotta
    Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy
    J Biol Chem 287:41352-63. 2012
    ..In conclusion, dexamethasone treatment may partly restore ATM activity in ataxia telangiectasia cells by a new molecular mechanism that overcomes most of the mutations so far described within this gene...
  2. ncbi Label-free quantification of activated NF-kappaB in biological samples by atomic force microscopy
    Michele Menotta
    Department of Biomolecular Sciences, University of Urbino Carlo Bo Via Saffi 2 61029 Urbino, PU, Italy
    Biosens Bioelectron 25:2490-6. 2010
    ..The present work represents the first quantification approach by AFM analysis. The results and the method may be used toward development of NF-kappaB based bio-diagnostic nano-device...
  3. pmc Molecular and functional characterization of a Rho GDP dissociation inhibitor in the filamentous fungus Tuber borchii
    Michele Menotta
    Center for Biochemistry, Medical Faculty, University of Cologne, Joseph Stelzmann Str, 52, 50931 Cologne, Germany
    BMC Microbiol 8:57. 2008
    ..Members of the guanine nucleotide dissociation inhibitor (GDI) family sequester Rho GTPases from the plasma membrane and keep them in an inactive form...
  4. ncbi Oxidized ultrashort nanotubes as carbon scaffolds for the construction of cell-penetrating NF-kappaB decoy molecules
    Rita Crinelli
    Department of Biomolecular Sciences, Biochemistry and Molecular Biology Section, University of Urbino Carlo Bo, 61029 Urbino, PU, Italy
    ACS Nano 4:2791-803. 2010
    ....
  5. doi Geographical traceability of Italian white truffle (Tuber magnatum Pico) by the analysis of volatile organic compounds
    Anna Maria Gioacchini
    Istituto di Ricerca sull Attività Motoria, Via I Maggetti 26, Universita degli Studi di Urbino Carlo Bo, 61029 Urbino, Italy
    Rapid Commun Mass Spectrom 22:3147-53. 2008
    ..Next, stepwise factorial discriminant analysis afforded a limited number of characteristic fragment ions that allowed a geographical classification of the truffles studied...
  6. doi Ubiquitin over-expression promotes E6AP autodegradation and reactivation of the p53/MDM2 pathway in HeLa cells
    Rita Crinelli
    Istituto di Chimica Biologica G Fornaini, Universita degli Studi di Urbino Carlo Bo, Via Saffi, 2, 61029 Urbino, PU, Italy
    Mol Cell Biochem 318:129-45. 2008
    ....
  7. doi Binding force measurement of NF-κB-ODNs interaction: an AFM based decoy and drug testing tool
    Michele Menotta
    Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via Saffi 2, 61029 Urbino PU, Italy
    Biosens Bioelectron 28:158-65. 2011
    ..A biological AFM based sensor is therefore considered appropriate for characterising transcription factors and selecting molecules to modulate their activity...
  8. ncbi Forward subtractive libraries containing genes transactivated by dexamethasone in ataxia-telangiectasia lymphoblastoid cells
    Sara Biagiotti
    Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via Saffi 2, 61029, Urbino, PU, Italy
    Mol Cell Biochem 392:13-30. 2014
    ..Moreover, the induction of a specific region of the ATM transcript has been identified as putative biomarker predictive of dexamethasone efficacy on ataxic patients. ..
  9. ncbi Hexose uptake in the plant symbiotic ascomycete Tuber borchii Vittadini: biochemical features and expression pattern of the transporter TBHXT1
    Emanuela Polidori
    Istituto di Ricerca sull Attività Motoria, Universita degli Studi di Urbino Carlo Bo, Via I Maggetti 26, 61029 Urbino, Italy
    Fungal Genet Biol 44:187-98. 2007
    ..Prolonged carbon starvation condition upregulates Tbhxt1, while its expression remains at basal level in the ectomycorrhizal tissue. The mode of regulation of Tbhxt1 is consistent with its role as a high-affinity d-glucose transporter...
  10. ncbi Identification and characterization of the Tuber borchii D-mannitol dehydrogenase which defines a new subfamily within the polyol-specific medium chain dehydrogenases
    Paola Ceccaroli
    Istituto di Chimica Biologica Giorgio Fornaini, Universita degli Studi di Urbino Carlo Bo, Via A Saffi 2, 61029, Urbino PU, Italy
    Fungal Genet Biol 44:965-78. 2007
    ..The enzyme identified a new group of proteins, most of them annotated in databases as hypothetical zinc-dependent dehydrogenases, forming a distinct subfamily among the polyol dehydrogenase family...
  11. doi Morphological and molecular modifications induced by different carbohydrate sources in Tuber borchii
    Antonella Amicucci
    Dipartimento di Scienze Biomolecolari, Universita degli Studi di Urbino Carlo Bo, Urbino, Italy
    J Mol Microbiol Biotechnol 18:120-8. 2010
    ..These mechanisms can lead to morphological modifications, including increased branching of the root which is necessary for the fungus to establish the symbiosis...
  12. ncbi Solid-phase microextraction gas chromatography/mass spectrometry: a new method for species identification of truffles
    Anna Maria Gioacchini
    Istituto di Ricerca sull Attività Motoria, Universita degli Studi di Urbino, Via Sasso 75 G, 61029 Urbino PU, Italy
    Rapid Commun Mass Spectrom 19:2365-70. 2005
    ..Moreover, this method offers the advantage of minimizing thermal, mechanical, and chemical modifications of the truffles, thereby reducing the risk of analytical artifacts...
  13. doi High resolution melting (HRM) analysis for the detection of ER22/23EK, BclI, and N363S polymorphisms of the glucocorticoid receptor gene
    Paolo Maltese
    Department of Biomolecular Sciences, University of Urbino, Via Saffi 2, Urbino, Italy
    J Steroid Biochem Mol Biol 113:269-74. 2009
    ..This is, at now, the less expensive and time-and work-saving method to detect GR mutations, providing precision, fast screening and high throughput capabilities...
  14. doi Effect of the redox state on HIV-1 tat protein multimerization and cell internalization and trafficking
    Raffaella Pierleoni
    Department of Molecular Sciences, University of Urbino Carlo Bo, Via Saffi 2, 61029, Urbino, Italy
    Mol Cell Biochem 345:105-18. 2010
    ..This is due to strong electrostatic and metal-binding interactions, whereas Tat dimerization involves metal-binding interactions as well as disulfide bond formation...
  15. ncbi Headspace solid-phase microextraction with gas chromatography and mass spectrometry in the investigation of volatile organic compounds in an ectomycorrhizae synthesis system
    Michele Menotta
    Istituto di Chimica Biologica Giorgio Fornaini, Universita degli Studi di Urbino, Via Saffi 2, 61029 Urbino PU, Italy
    Rapid Commun Mass Spectrom 18:206-10. 2004
    ..Twenty-nine of these VOCs were produced only during the interaction phase between the two partners, leading to a hypothesis that these molecules might act as molecular messengers in order to pilot the ectomycorrhizae formation...