L Menghini

Summary

Affiliation: University of Chieti
Country: Italy

Publications

  1. ncbi request reprint Glaucopines A and B, new cyathane diterpenes from the fruiting bodies of Sarcodon glaucopus
    Massimo Curini
    Dipartimento di Chimica e Tecnologia del Farmaco, Sez Chimica Organica, Universita degli Studi, Perugia, Italy
    Planta Med 71:194-6. 2005
  2. ncbi request reprint Anti-inflammatory and analgesic effects of Spartium junceum L. flower extracts: a preliminary study
    Luigi Menghini
    Department of Drug Science, University of Chieti, Chieti, Italy
    J Med Food 9:386-90. 2006
  3. ncbi request reprint Effect of phytochemical concentrations on biological activities of cranberry extracts
    L Menghini
    Dipartimento di Scienze del Farmaco, Università di Chieti Pescara, Chieti, Italy
    J Biol Regul Homeost Agents 25:27-35. 2011
  4. ncbi request reprint Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation
    L Menghini
    Dipartimento di Scienze del Farmaco, Università G D Annunzio Chieti Pescara, Italy
    Int J Immunopathol Pharmacol 23:601-10. 2010
  5. ncbi request reprint A multiherbal formulation influencing immune response in vitro
    L Menghini
    Department of Drug Science, University G D Annunzio, Chieti, Italy
    Minerva Med 103:13-21. 2012
  6. doi request reprint Phytochemical investigation on leaf extract of Cordia salicifolia Cham
    Luigi Menghini
    Dipartimento di Scienze del Farmaco, University G D Annunzio, Chieti Scalo, Italy
    J Med Food 11:193-4. 2008
  7. doi request reprint Chemical composition and inhibitory activity against Helicobacter pylori of the essential oil of Apium nodiflorum (Apiaceae)
    Luigi Menghini
    Dipartimento di Scienze del Farmaco, Università G D Annunzio Chieti Pescara, Chieti Scalo, Italy
    J Med Food 13:228-30. 2010
  8. doi request reprint Antiinflammatory activity of coumarins from Ligusticum lucidum Mill. subsp. cuneifolium (Guss.) Tammaro (Apiaceae)
    Luigi Menghini
    Dipartimento di Scienze del Farmaco, University G d Annunzio of Chieti Pescara, Via dei Vestini 31, 66013 Chieti Scalo, Italy
    Phytother Res 24:1697-9. 2010
  9. ncbi request reprint In vitro inhibitory activity of boropinic acid against Helicobacter pylori
    Francesco Epifano
    Dipartimento di Scienze del Farmaco, Via dei Vestini 31, 66013 Chieti Scalo CH, Italy
    Bioorg Med Chem Lett 16:5523-5. 2006
  10. doi request reprint Antiinflammatory effects in THP-1 cells treated with verbascoside
    Lorenza Speranza
    Department of Biomorphology, University G D Annunzio, Chieti, Italy
    Phytother Res 24:1398-404. 2010

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Glaucopines A and B, new cyathane diterpenes from the fruiting bodies of Sarcodon glaucopus
    Massimo Curini
    Dipartimento di Chimica e Tecnologia del Farmaco, Sez Chimica Organica, Universita degli Studi, Perugia, Italy
    Planta Med 71:194-6. 2005
    ..3 micromol/cm2, 61 % edema reduction)...
  2. ncbi request reprint Anti-inflammatory and analgesic effects of Spartium junceum L. flower extracts: a preliminary study
    Luigi Menghini
    Department of Drug Science, University of Chieti, Chieti, Italy
    J Med Food 9:386-90. 2006
    ..The data from this preliminary study reveal interesting pharmacological properties of S. junceum L. flowers extract related to the marked analgesic activity and the absence of gastric ulcerogenic activity...
  3. ncbi request reprint Effect of phytochemical concentrations on biological activities of cranberry extracts
    L Menghini
    Dipartimento di Scienze del Farmaco, Università di Chieti Pescara, Chieti, Italy
    J Biol Regul Homeost Agents 25:27-35. 2011
    ..Only in DPPH test the free radical scavenging activity seemed to be directly related to proanthocyanidins content...
  4. ncbi request reprint Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation
    L Menghini
    Dipartimento di Scienze del Farmaco, Università G D Annunzio Chieti Pescara, Italy
    Int J Immunopathol Pharmacol 23:601-10. 2010
    ..The positive results of the cell viability test, together with the protective and antiradical activity confirm the rationale for the use of these ingredients in commercial formulations as a health aid tool in modern phytotherapy...
  5. ncbi request reprint A multiherbal formulation influencing immune response in vitro
    L Menghini
    Department of Drug Science, University G D Annunzio, Chieti, Italy
    Minerva Med 103:13-21. 2012
    ..Aim of this study was to evaluate the effects of phytocomplexes of Uncaria, Shiitake and Ribes in terms of viability and inflammatory response on immune cell-derived cultures...
  6. doi request reprint Phytochemical investigation on leaf extract of Cordia salicifolia Cham
    Luigi Menghini
    Dipartimento di Scienze del Farmaco, University G D Annunzio, Chieti Scalo, Italy
    J Med Food 11:193-4. 2008
    ..53%). The major component of the extract exhibited a very weak activity as an inhibitor of growth of Helicobacter pylori in vitro (minimum inhibitory concentration = 200 microg/mL)...
  7. doi request reprint Chemical composition and inhibitory activity against Helicobacter pylori of the essential oil of Apium nodiflorum (Apiaceae)
    Luigi Menghini
    Dipartimento di Scienze del Farmaco, Università G D Annunzio Chieti Pescara, Chieti Scalo, Italy
    J Med Food 13:228-30. 2010
    ..62%) were the main components. The antimicrobial activity of the essential oil was assayed in vitro against Helicobacter pylori (strain DSMZ 4867), resulting in a minimum inhibitory concentration value of 12.5 microg/mL...
  8. doi request reprint Antiinflammatory activity of coumarins from Ligusticum lucidum Mill. subsp. cuneifolium (Guss.) Tammaro (Apiaceae)
    Luigi Menghini
    Dipartimento di Scienze del Farmaco, University G d Annunzio of Chieti Pescara, Via dei Vestini 31, 66013 Chieti Scalo, Italy
    Phytother Res 24:1697-9. 2010
    ..Each compound (0.3 μmol/cm(2) ) induced a significant oedema reduction and compound 4 exerted an effect similar to that of the equimolar dose of the reference drug indomethacin...
  9. ncbi request reprint In vitro inhibitory activity of boropinic acid against Helicobacter pylori
    Francesco Epifano
    Dipartimento di Scienze del Farmaco, Via dei Vestini 31, 66013 Chieti Scalo CH, Italy
    Bioorg Med Chem Lett 16:5523-5. 2006
    ..Boropinic acid, active principle isolated from Boronia pinnata (Fam. Rutaceae), was seen to be the most effective compound with a MIC value of 1.62 microg/mL...
  10. doi request reprint Antiinflammatory effects in THP-1 cells treated with verbascoside
    Lorenza Speranza
    Department of Biomorphology, University G D Annunzio, Chieti, Italy
    Phytother Res 24:1398-404. 2010
    ..Based on these results it is hypothesized that verbascoside has antiinflammatory properties since it reduces the production of superoxide radicals and consequently reduces the activity of iNOS...
  11. ncbi request reprint Preliminary evaluation on anti-inflammatory and analgesic effects of Sideritis syriaca L. herba extracts
    Luigi Menghini
    Department of Drug Science, University of Chieti, Chieti, Italy
    J Med Food 8:227-31. 2005
    ..syriaca L. herba extracts related to the marked analgesic activity and the absence of gastric ulcerogenic activity. The same is for anti-inflammatory activity, but in this case it seems to be related only to the apolar fraction...
  12. ncbi request reprint Natural coumarins as a novel class of neuroprotective agents
    Francesco Epifano
    Dipartimento di Scienze del Farmaco, Università G d Annunzio di Chieti Pescara, Chieti Scalo, Italy
    Mini Rev Med Chem 9:1262-71. 2009
    ..The aim of this manuscript is to review what has been reported so far in the literature about coumarins as a novel class of pharmacologically active compounds in chemoprevention and/or therapy of these diseases...
  13. ncbi request reprint Chemistry and pharmacology of oxyprenylated secondary plant metabolites
    Francesco Epifano
    Dipartimento di Scienze del Farmaco, Università G d Annunzio di Chieti Pescara, Chieti Scalo, Italy
    Phytochemistry 68:939-53. 2007
    ..The aim of this review is to examine in detail the different types of oxyprenylated natural compounds from a phytochemical and pharmacological point of view...
  14. doi request reprint Comparison of three different extraction methods and HPLC determination of the anthraquinones aloe-emodine, emodine, rheine, chrysophanol and physcione in the bark of Rhamnus alpinus L. (Rhamnaceae)
    S Genovese
    Dipartimento di Scienze del Farmaco, Università degli Studi G d Annunzio Chieti Pescara, Via dei Vestini 31, 66100 Chieti CH, Italy
    Phytochem Anal 21:261-7. 2010
    ..Thus, using simple, reliable and accurate analytical methods for the determination of anthraquinones in R. alpinus extracts allows comparative study of different methods of extraction...
  15. ncbi request reprint Ginkgo biloba leaf extract reverses amyloid beta-peptide-induced isoprostane production in rat brain in vitro
    Luigi Brunetti
    Department of Drug Sciences, G D Annunzio University, School of Pharmacy, Chieti, Italy
    Planta Med 72:1296-9. 2006
    ..This suggests that the oxygen radical scavenging properties of the Ginkgo biloba extract are fully effective in young, as well as in old rats, showing a greater inhibition of isoprostane production in the latter...
  16. doi request reprint Rhamnus alpinus leaf extract suppresses lipopolysaccharide-induced, monocyte-derived macrophage chemokine secretion
    Annalisa Chiavaroli
    Dipartimento di Science del Farmaco, Via dei Vestini 31, 66013 Chieti Scalo, Chieti, Italy
    Inflammation 31:313-8. 2008
    ..This may impede the progression and aggravation of inflammation given that the migration of immune cells plays an important role in the outcome of periodontitis...
  17. doi request reprint Antioxidant effects of garlic in young and aged rat brain in vitro
    Luigi Brunetti
    Department of Drug Sciences, School of Pharmacy, G D Annunzio University, Chieti, Italy
    J Med Food 12:1166-9. 2009
    ..In conclusion, garlic supplementation could be effective in preventing brain oxidative damage in young animals, whereas the aging brain seems to be resistant to the antioxidant effects of garlic, in vitro...
  18. ncbi request reprint Fatty acids profile and antiinflammatory activity of Nonea setosa R. et S
    Massimo Curini
    Dipartimento di Chimica e Tecnologia del Farmaco, Sezione di Chimica Organica, Perugia, Italy
    Phytother Res 20:422-3. 2006
    ..GC-MS analysis of the most active fraction revealed the presence of high amounts of polyunsaturated fatty acids...
  19. ncbi request reprint 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid: a novel promising cancer chemopreventive agent
    Massimo Curini
    Dipartimento di Chimica e Tecnologia del Farmaco, Sezione di Chimica Organica, Via del Liceo, Perugia, Italy
    Anticancer Agents Med Chem 6:571-7. 2006
    ..The aim of this review is to examine in detail the properties of the title compound so far reported in the literature from a chemical and pharmacological point of view...