Andreoni Massimo

Summary

Affiliation: University of Rome Tor Vergata
Country: Italy

Publications

  1. doi request reprint Incidence of malignancies in HIV-infected patients and prognostic role of current CD4 cell count: evidence from a large Italian cohort study
    M C F Prosperi
    Istituto di Clinica delle Malattie Infettive, Universita Cattolica del Sacro Cuore, Rome, Italy
    Clin Infect Dis 50:1316-21. 2010
  2. pmc A stable CC-chemokine receptor (CCR)-5 tropic virus is correlated with the persistence of HIV RNA at less than 2.5 copies in successfully treated naïve subjects
    Saverio Giuseppe Parisi
    Department of Molecular Medicine, University of Padova, Padova, Italy
    BMC Infect Dis 13:314. 2013
  3. ncbi request reprint HIV-HCV co-infection: epidemiology, pathogenesis and therapeutic implications
    M Andreoni
    Clinical Infectious Diseases, Tor Vergata University, Rome, Italy
    Eur Rev Med Pharmacol Sci 16:1473-83. 2012
  4. pmc Determinants of access to experimental antiretroviral drugs in an Italian cohort of patients with HIV: a multilevel analysis
    Enrico Girardi
    Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases L, Spallanzani, IRCCS, Via Portuense 292, 00149, Rome, Italy
    BMC Health Serv Res 12:38. 2012
  5. ncbi request reprint Positioning of HIV-protease inhibitors in clinical practice
    M Andreoni
    Department of Public Health and Cell Biology, School of Medicine, University of Rome Tor Vergata, Rome, Italy
    Eur Rev Med Pharmacol Sci 16:10-8. 2012
  6. pmc Complication of nasal piercing by Staphylococcus aureus endocarditis: a case report and a review of literature
    Battagin Giuliana
    Department of Clinical Infectious Diseases and Cardiac Surgery, Tor Vergata University Hospital, V, Montpellier 1, 00133, Rome, Italy
    Cases J 3:37. 2010
  7. ncbi request reprint Saquinavir delays the emergence of zidovudine resistance in HIV-1 seropositive patients treated with combination therapy
    M Andreoni
    Infectious Diseases, Department of Public Health and Cellular Biology, University of Rome Tor Vergata, Italy
    J Med Virol 56:332-6. 1998
  8. ncbi request reprint High seroprevalence of antibodies to human herpesvirus-8 in Egyptian children: evidence of nonsexual transmission
    M Andreoni
    Infectious Diseases Institute, University of Tor Vergata, Rome, Italy
    J Natl Cancer Inst 91:465-9. 1999
  9. ncbi request reprint Cellular proviral HIV-DNA decline and viral isolation in naïve subjects with <5000 copies/ml of HIV-RNA and >500 x 10(6)/l CD4 cells treated with highly active antiretroviral therapy
    M Andreoni
    Department of Public Health, University of Rome Tor Vergata, Italy
    AIDS 14:23-9. 2000
  10. ncbi request reprint Primary human herpesvirus 8 infection in immunocompetent children
    Massimo Andreoni
    Department of Public Health and Cellular Biology, University Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    JAMA 287:1295-300. 2002

Detail Information

Publications78

  1. doi request reprint Incidence of malignancies in HIV-infected patients and prognostic role of current CD4 cell count: evidence from a large Italian cohort study
    M C F Prosperi
    Istituto di Clinica delle Malattie Infettive, Universita Cattolica del Sacro Cuore, Rome, Italy
    Clin Infect Dis 50:1316-21. 2010
    ..9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM...
  2. pmc A stable CC-chemokine receptor (CCR)-5 tropic virus is correlated with the persistence of HIV RNA at less than 2.5 copies in successfully treated naïve subjects
    Saverio Giuseppe Parisi
    Department of Molecular Medicine, University of Padova, Padova, Italy
    BMC Infect Dis 13:314. 2013
    ..To determine if tropism for CXCR4 or CCR5 correlates with cellular HIV DNA load, residual viraemia and CD4 count in 219 successfully treated naive subjects with HIV infection enrolled in five infectious diseases units in Northeastern Italy...
  3. ncbi request reprint HIV-HCV co-infection: epidemiology, pathogenesis and therapeutic implications
    M Andreoni
    Clinical Infectious Diseases, Tor Vergata University, Rome, Italy
    Eur Rev Med Pharmacol Sci 16:1473-83. 2012
    ....
  4. pmc Determinants of access to experimental antiretroviral drugs in an Italian cohort of patients with HIV: a multilevel analysis
    Enrico Girardi
    Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases L, Spallanzani, IRCCS, Via Portuense 292, 00149, Rome, Italy
    BMC Health Serv Res 12:38. 2012
    ..Identification of the determinants of access to investigational drugs is important to promote equity and scientific validity in clinical research. We aimed to analyze factors associated with the use of experimental antiretrovirals in Italy...
  5. ncbi request reprint Positioning of HIV-protease inhibitors in clinical practice
    M Andreoni
    Department of Public Health and Cell Biology, School of Medicine, University of Rome Tor Vergata, Rome, Italy
    Eur Rev Med Pharmacol Sci 16:10-8. 2012
    ....
  6. pmc Complication of nasal piercing by Staphylococcus aureus endocarditis: a case report and a review of literature
    Battagin Giuliana
    Department of Clinical Infectious Diseases and Cardiac Surgery, Tor Vergata University Hospital, V, Montpellier 1, 00133, Rome, Italy
    Cases J 3:37. 2010
    ....
  7. ncbi request reprint Saquinavir delays the emergence of zidovudine resistance in HIV-1 seropositive patients treated with combination therapy
    M Andreoni
    Infectious Diseases, Department of Public Health and Cellular Biology, University of Rome Tor Vergata, Italy
    J Med Virol 56:332-6. 1998
    ..Combination therapy may delay the emergence of phenotypic resistance to either drugs in the short term and to ZDV, but not to SQV, at least after 1 year...
  8. ncbi request reprint High seroprevalence of antibodies to human herpesvirus-8 in Egyptian children: evidence of nonsexual transmission
    M Andreoni
    Infectious Diseases Institute, University of Tor Vergata, Rome, Italy
    J Natl Cancer Inst 91:465-9. 1999
    ..To evaluate the role of other transmission routes, especially in developing countries, we estimated the seroprevalence of HHV-8 in Egyptian children, who, if seropositive, would have acquired the virus through a nonsexual route...
  9. ncbi request reprint Cellular proviral HIV-DNA decline and viral isolation in naïve subjects with <5000 copies/ml of HIV-RNA and >500 x 10(6)/l CD4 cells treated with highly active antiretroviral therapy
    M Andreoni
    Department of Public Health, University of Rome Tor Vergata, Italy
    AIDS 14:23-9. 2000
    ..To evaluate the decay rate of cellular proviral HIV-DNA and viral replication in patients receiving highly active antiretroviral therapy (HAART) in the very early phase of infection...
  10. ncbi request reprint Primary human herpesvirus 8 infection in immunocompetent children
    Massimo Andreoni
    Department of Public Health and Cellular Biology, University Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    JAMA 287:1295-300. 2002
    ..Human herpesvirus 8 (HHV-8) infection causes Kaposi sarcoma and lymphoproliferative disorders in immunosuppressed adults. Its manifestations in immunocompetent hosts are unknown...
  11. pmc High prevalence of M184 mutation among patients with viroimmunologic discordant responses to highly active antiretroviral therapy and outcomes after change of therapy guided by genotypic analysis
    Emanuele Nicastri
    Department of Public Health, University of Rome Tor Vergata, Rome, Italy
    J Clin Microbiol 41:3007-12. 2003
    ..A relationship between the M184V mutation and a viroimmunologic discordant response to HAART was found. After the genotypic analysis-driven change of therapy, similar rates of virologic suppression were detected in the two groups...
  12. ncbi request reprint Replication capacity, biological phenotype, and drug resistance of HIV strains isolated from patients failing antiretroviral therapy
    Emanuele Nicastri
    National Institute of Infectious Diseases, IRCCS L Spallanzani, Rome, Italy
    J Med Virol 69:1-6. 2003
    ..In patients failing HAART, the detection of HIV isolates with the R5 biological phenotype correlates with CD4+ cell count, an impaired replication capacity, and a high number of drug-resistance mutations...
  13. pmc Drug-associated resistance mutations in plasma and peripheral blood mononuclear cells of human immunodeficiency virus type 1-infected patients for whom highly active antiretroviral therapy is failing
    Loredana Sarmati
    Department of Public Health, University of Rome Tor Vergata, Rome, Italy
    J Clin Microbiol 41:1760-2. 2003
    ..85). The mutations with the lowest agreement were 20R, 63P, and 84V in the protease gene and 184V in the reverse transcriptase gene. In eight patients, primary drug resistance mutations were detected only in PBMCs...
  14. ncbi request reprint Clinical outcome after 4 years follow-up of HIV-seropositive subjects with incomplete virologic or immunologic response to HAART
    Emanuele Nicastri
    National Institute of Infectious Diseases, IRCCS L Spallanzani, Rome, Italy
    J Med Virol 76:153-60. 2005
    ..001). After 4 years of HAART, the risk of clinical progression in patients with immunologic only or virologic only response is low but still higher than in complete responder patients...
  15. ncbi request reprint Residual viraemia in subjects with chronic HIV infection and viral load < 50 copies/ml: the impact of highly active antiretroviral therapy
    Lucia Palmisano
    Istituto Superiore di Sanita, Department of Drug Research and Evaluation, Rome, Italy
    AIDS 19:1843-7. 2005
    ..To determine factors associated with < 2.5 copies/ml plasma HIV RNA in subjects treated with highly active antiretroviral therapy (HAART) and with viraemia < 50 copies/ml...
  16. pmc Association between cellular human immunodeficiency virus DNA level and immunological parameters in patients with undetectable plasma viremia level during highly active antiretroviral therapy
    Loredana Sarmati
    Department of Public Health and Cellular Biology, University of Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    J Clin Microbiol 43:6183-5. 2005
    ..005) CD4 counts and a prolonged duration of treatment (P = 0.001). At adjusted analysis, prolonged duration of treatment was independently associated with lower (P = 0.006) and undetectable (P < 0.001) HIV DNA values...
  17. ncbi request reprint Cellular HIV-1 DNA quantitation in patients during simplification therapy with protease inhibitor-sparing regimens
    Loredana Sarmati
    Department of Public Health and Cellular Biology, University of Rome Tor Vergata, Rome, Italy
    J Med Virol 79:880-6. 2007
    ..In addition, sustained suppression of the plasma viral load was significantly correlated with low levels of proviral DNA before treatment simplification...
  18. ncbi request reprint Non-B HIV type 1 subtypes: replicative capacity and response to antiretroviral therapy
    Emanuele Nicastri
    National Institute of Infectious Diseases, IRCCS L Spallanzani, Rome, Italy
    AIDS Res Hum Retroviruses 20:816-8. 2004
  19. ncbi request reprint Viral growth assay to evaluate the replicative capacity of HIV-1 isolates
    Emanuele Nicastri
    National Institute of Infectious Diseases, IRCCS L Spallanzani, Rome, Italy
    J Virol Methods 115:199-205. 2004
    ..A viral assay to evaluate the HIV replicative capacity is described. The high variability of replicative capacity confirms the need to undertake replicative capacity assay using the whole virus...
  20. ncbi request reprint Sex issues in HIV-1-infected persons during highly active antiretroviral therapy: a systematic review
    Emanuele Nicastri
    National Institute for Infectious Diseases, IRCCS Lazzaro Spallanzani, Rome, Italy
    J Antimicrob Chemother 60:724-32. 2007
    ..Studies of possible differences between men and women in the course of HIV infection give conflicting results. The objective of this study was to assess sex differences during HAART...
  21. ncbi request reprint Prevalence of HHV-8 infection in Albanian adults and association with HBV and HCV
    Nicola Schinaia
    Istituto Superiore di Sanità National Health Institute, Rome, Italy
    Eur J Epidemiol 19:467-9. 2004
    ..We found 20% anti-HHV-8 antibodies, about 10% HbsAg-positive, and 67% anti-HBc antibodies; anti-HCV antibody prevalence was 3%. It remains to be determined whether HHV-8 infection and HCV infection have common modes of transmission...
  22. ncbi request reprint Effect of multiple herpesvirus infections on the progression of HIV disease in a cohort of HIV seroconverters
    Barbara Suligoi
    Reparto AIDS e MST, Istituto Superiore di Sanita, Rome, Italy
    J Med Virol 69:182-7. 2003
    ..However, even after excluding Kaposi's sarcoma from the AIDS-defining endpoints, a slightly increased risk for participants with four herpesvirus infections remained...
  23. pmc A prognostic model for estimating the time to virologic failure in HIV-1 infected patients undergoing a new combination antiretroviral therapy regimen
    Mattia C F Prosperi
    Infectious Diseases Clinic, Catholic University of the Sacred Heart, Rome, Italy
    BMC Med Inform Decis Mak 11:40. 2011
    ..However, their relative-hazard for the time to virologic failure has not been thoroughly investigated, and an expert system that is able to predict how long a new cART regimen will remain effective has never been designed...
  24. ncbi request reprint Phenotypic resistance testing
    Massimo Andreoni
    Department of Public Health, University Tor Vergata, Rome, Italy
    Scand J Infect Dis Suppl 106:35-6. 2003
    ..However, clinical validation will be necessary to delineate which approach is better...
  25. doi request reprint Detection of drug resistance mutations at low plasma HIV-1 RNA load in a European multicentre cohort study
    Mattia C F Prosperi
    Clinic of Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy
    J Antimicrob Chemother 66:1886-96. 2011
    ....
  26. ncbi request reprint Infection with human herpesvirus-8 and its correlation with hepatitis B virus and hepatitis C virus markers among rural populations in Cambodia
    Loredana Sarmati
    Department of Public Health, Tor Vergata University, Rome, Italy
    Am J Trop Med Hyg 68:501-2. 2003
    ..Human herpesvirus-8, which shows a high rate of infection during childhood, does not seem to have the same pattern of transmission as HBV. This suggests very early acquisition of infection with HHV-8 in Cambodia...
  27. ncbi request reprint Gender differences in clinical progression of HIV-1-infected individuals during long-term highly active antiretroviral therapy
    Emanuele Nicastri
    National Institute for Infectious Diseases, IRCCS L Spallanzani, Rome, Italy
    AIDS 19:577-83. 2005
    ..To assess gender differences in the long-term clinical, virological and immunological outcomes during highly active antiretroviral therapy (HAART)...
  28. pmc Discordance between genotypic and phenotypic drug resistance profiles in human immunodeficiency virus type 1 strains isolated from peripheral blood mononuclear cells
    Loredana Sarmati
    Department of Public Health, University of Rome Tor Vergata IRCCS L Spallanzani, Italy
    J Clin Microbiol 40:335-40. 2002
    ..Despite the low number of patients and the short follow-up period, this study suggests that during failing therapy with analogue nucleosides, a phenotypic analysis could be performed in spite of an HIV genotypic sensitivity pattern...
  29. ncbi request reprint A randomized controlled trial of a protease inhibitor (saquinavir) in combination with zidovudine in previously untreated patients with advanced HIV infection
    S Vella
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy
    Antivir Ther 1:129-40. 1996
    ..The combination of drugs with different mechanisms of action represents an advance in the treatment of HIV infection...
  30. ncbi request reprint Human herpesvirus-8 infection in pregnancy and labor: lack of evidence of vertical transmission
    Loredana Sarmati
    Department of Public Health and Cellular Biology, University Tor Vergata, Rome, Italy
    J Med Virol 72:462-6. 2004
    ..None of the amniotic fluid and cord blood samples had detectable HHV-8 DNA sequences. This study suggests that vertical transmission of HHV-8 is unlikely or, at least, very rare...
  31. doi request reprint HIV-1 dual/mixed tropic isolates show different genetic and phenotypic characteristics and response to maraviroc in vitro
    Valentina Svicher
    Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Antiviral Res 90:42-53. 2011
    ....
  32. ncbi request reprint No protective effect of acyclovir on HIV disease progression in a cohort of HSV-2-HIV-infected individuals
    Barbara Suligoi
    Reparto AIDS e MST, Istituto Superiore di Sanita, Rome, Italy
    Antivir Ther 7:289-91. 2002
    ..In conclusion, treatment with acyclovir does not seem to prolong significantly survival to AIDS among HIV-positive individuals who are HSV-2-infected...
  33. ncbi request reprint Discordant response to antiretroviral therapy: HIV isolation, genotypic mutations, T-cell proliferation and cytokine production
    Gabriella d'Ettorre
    Department of Infectious and Tropical Diseases, La Sapienza University, Rome, Italy
    AIDS 16:1877-85. 2002
    ..To study virologic and immunologic factors associated with discordant treatment response in HIV-infected patients receiving highly active antiretroviral therapy (HAART)...
  34. doi request reprint Low rate of virological failure and maintenance of susceptibility to HIV-1 protease inhibitors with first-line lopinavir/ritonavir-based antiretroviral treatment in clinical practice
    Mattia C F Prosperi
    Clinic of Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy
    J Med Virol 82:1996-2003. 2010
    ..Despite the likely differences in patient population and adherence, both the low rate of virological failure and the lack of development of LPV/rtv resistance documented in clinical trials are thus confirmed in clinical practice...
  35. ncbi request reprint Decrease of replicative capacity of HIV isolates after genotypic guided change of therapy
    L Sarmati
    Department of Public Health, University of Rome Tor Vergata, Rome, Italy
    J Med Virol 72:511-6. 2004
    ..In patients failing HAART, the impaired replication capacity of HIV strains could justify the persistence of an immune recovery...
  36. ncbi request reprint Human herpesvirus 8 seropositivity and risk of Kaposi's sarcoma and other acquired immunodeficiency syndrome-related diseases
    G Rezza
    G Rezza, M Dorrucci, P Pezzotti Centro Operativo AIDS, P Monini, B Ensoli Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy
    J Natl Cancer Inst 91:1468-74. 1999
    ..Human herpesvirus 8 (HHV8) has also been implicated in KS. We investigated several factors that may determine the onset of KS, particularly HHV8 infection in individuals after becoming seropositive for HIV...
  37. ncbi request reprint Prevalence and risk factors for human herpesvirus 8 infection in northern Cameroon
    G Rezza
    Laboratory of Epidemiology, Istituto Superiore di Sanita, Rome, Italy
    Sex Transm Dis 27:159-64. 2000
    ..The modes of transmission of HHV-8 are still unclear...
  38. ncbi request reprint Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations
    L Sarmati
    Department of Public Health, University of Rome Tor Vergata, Rome, Italy
    J Med Virol 65:631-6. 2001
    ..AZT-like resistance mutations in AZT-naive patients seem to correlate with a virological failure during long-term stavudine therapy...
  39. ncbi request reprint Discordant response to HAART: reduction of viremia and replicative capacity of HIV strains in patients after genotype guided change of therapy
    L Sarmati
    Department of Public Health, University of Rome Tor Vergata, Rome
    New Microbiol 27:95-8. 2004
    ..1-74.5%). The HIV strains of patients failing HAART showed a progressive impaired replication capacity. In patients failing HAART the impaired replication capacity of HIV strains could justify the persistence of an immune recovery...
  40. ncbi request reprint Prevalence and determinants of herpes simplex virus type 2 infection in a cohort of HIV-positive individuals in Italy
    Barbara Suligoi
    Reparto AIDS e MST, Istituto Superiore di Sanita, Rome, Italy
    Sex Transm Dis 29:665-7. 2002
    ..Herpes simplex virus type 2 (HSV-2) infections may be a risk factor for the transmission of HIV. Data on the prevalence of HSV-2 infection among HIV-positive individuals are scarce...
  41. ncbi request reprint Infection with human immunodeficiency virus, herpes simplex virus type 2, and human herpes virus 8 in remote villages of southwestern Papua New Guinea
    B Suligoi
    Istituto Superiore di Sanita, Rome, Italy
    Am J Trop Med Hyg 72:33-6. 2005
    ....
  42. pmc Human herpesvirus-8 and other viral infections, Papua New Guinea
    G Rezza
    Istituto Superiore di Sanita, Rome, Italy
    Emerg Infect Dis 7:893-5. 2001
    ..Our data suggest that HHV-8 has been endemic on the island for a long time and that the epidemiologic pattern of HHV-8 is more similar to that of herpes simplex virus-2 than hepatitis C virus...
  43. ncbi request reprint Human herpesvirus 8 and human herpesvirus 2 infections in prison population
    L Sarmati
    Clinic of Infectious Diseases, University of Tor Vergata, Rome, Italy
    J Med Virol 79:167-73. 2007
    ..004). A relatively high seroprevalence of HHV-8 and HSV-2 among Italian prison inmates was found. The association of HHV-8 and HSV-2 infections suggest sexual transmission of these viruses among Italian prison inmates...
  44. ncbi request reprint [Interstitial pulmonary fibrosis in chronic HCV hepatitis treated with interferon]
    C Sarrecchia
    Dipartimento di Sanita Pubblica, Universita Tor Vergata, Roma
    Recenti Prog Med 92:336-9. 2001
    ..The correlation among interstitial pulmonary fibrosis, HCV infection and interferon treatment is discussed; however in the described case, the pulmonary pathology was correlated to interferon treatment...
  45. pmc Neutralizing antibodies against autologous human immunodeficiency virus Type 1 isolates in patients with increasing CD4 cell counts despite incomplete virus suppression during antiretroviral treatment
    L Sarmati
    Department of Public Health, University of Rome Tor Vergata, Rome, Italy
    Clin Diagn Lab Immunol 8:822-4. 2001
    ..0001). The HIV-specific humoral immune response could play a role during antiretroviral treatment to improve immunological function despite an incomplete suppression of viral load...
  46. ncbi request reprint Correlates of human herpes virus-8 and herpes simplex virus type 2 infections in Northern Cameroon
    A Volpi
    Department of Public Health, University Tor Vergata, Rome, Italy
    J Med Virol 74:467-72. 2004
    ..019) and latent (P = 0.021) HHV-8 antigens. These results suggest that HSV-2 infection can contribute to sexual transmission of HHV-8 infection...
  47. ncbi request reprint In vitro fluconazole susceptibility of 1565 clinical isolates of Candida species evaluated by the disk diffusion method performed using NCCLS M44-A guidelines
    Gian Piero Testore
    University of Rome Tor Vergata, Department of Public Health, Rome, Italy
    Diagn Microbiol Infect Dis 50:187-92. 2004
    ....
  48. doi request reprint Identification and structural characterization of novel genetic elements in the HIV-1 V3 loop regulating coreceptor usage
    Valentina Svicher
    Department of Experimental Medicine and Biochemical Sciences, University of Tor Vergata, Rome, Italy
    Antivir Ther 16:1035-45. 2011
    ..Knowledge of how different genetic signatures of gp120 V3 domain effect the strength of this interaction is limited...
  49. ncbi request reprint Performance of genotypic tropism testing in clinical practice using the enhanced sensitivity version of Trofile as reference assay: results from the OSCAR Study Group
    Valentina Svicher
    University of Rome Tor Vergata, Department of Experimental Medicine, Roma, Italy
    New Microbiol 33:195-206. 2010
    ..The goal of the OSCAR programme is to evaluate the performances of genotypic HIV-1 tropism testing in clinical practice using the enhanced sensitivity version of Trofile (ESTA) as reference-assay...
  50. ncbi request reprint A seroprevalence study of human herpesvirus type 8 (HHV8) in eastern and Central Africa and in the Mediterranean area
    D Serraino
    Dipartimento di Epidemiologia, Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, IRCCS, Rome, Italy
    Eur J Epidemiol 17:871-6. 2001
    ..The high prevalence of HHV8 infection in newborns, children and adolescents in Egypt, in eastern and in Central Africa strongly suggests the existence of transmission modes other than sexual...
  51. ncbi request reprint Human immunodeficiency virus-1 specific and natural cellular immunity in HIV seronegative subjects with multiple sexual exposures to virus
    E Nicastri
    I.R.C.C.S. L. Spallanzani, Rome, Italy
    J Med Virol 64:232-7. 2001
    ..The protection from sexual HIV transmission appears to be the result of a network of different humoral and cellular factors...
  52. ncbi request reprint Once-a-day (QD) vs. twice-daily (BID) nevirapine as simplification in PI-treated patients after 2 mos. of BID induction
    Renato Maserati
    Foundation IRCCS Policlinico San Matteo Hospital, Infectious Diseases, Pavia, Italy
    Curr HIV Res 9:166-73. 2011
    ..Apparently, no significant differences between the QD and BID NVP groups were found, in terms of virological failures or tolerability/toxicity. The switch to NVP may be safely pursued with a QD schedule...
  53. doi request reprint A novel methodology for large-scale phylogeny partition
    Mattia C F Prosperi
    Clinic of Infectious Diseases, Catholic University of the Sacred Heart, Rome, Italy
    Nat Commun 2:321. 2011
    ..Our method takes an advantage of a flexible notion of transmission cluster and can become a general framework to analyse other epidemics...
  54. pmc Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors
    Francesca Ceccherini-Silberstein
    Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Antimicrob Agents Chemother 54:3938-48. 2010
    ....
  55. pmc Switching of inferred tropism caused by HIV during interruption of antiretroviral therapy
    L Sarmati
    Clinical Infectious Diseases, Tor Vergata University, Rome, Italy
    J Clin Microbiol 48:2586-8. 2010
    ..At treatment resumption, HIV inferred tropism switched from the X4 strain to the R5 variant in 9 patients (60%). These patients had a prolonged length of treatment interruption compared to that of those who still carried the X4 strain...
  56. ncbi request reprint Kaposi's sarcoma following malignant mesothelioma
    V Ascoli
    Department of Experimental Medicine and Pathology, University La Sapienza, Rome, Italy
    Virchows Arch 435:612-5. 1999
    ..Besides the possibility of a casual association, we hypothesize that mesothelioma-linked factors may have contributed to the development of Kaposi's sarcoma in the presence of HHV8 infection...
  57. ncbi request reprint Does HHV-8 have a protective role on the development of HIV encephalopathy? Italian HIV-Seroconversion Study
    G Rezza
    AIDS and STD Unit, Istituto Superiore di Sanita, Rome, Italy
    Neurology 53:2032-6. 1999
    ..To evaluate risk factors for HIV encephalopathy and whether Kaposi's sarcoma (KS) and coinfection with human herpesvirus 8 (HHV-8) protect against this disease in a cohort of HIV seroconverters...
  58. doi request reprint Prognostic factors of long-term CD4+count-guided interruption of antiretroviral treatment
    L Sarmati
    Clinic of Infectious Diseases, Tor Vergata University, Rome, Italy
    J Med Virol 81:481-7. 2009
    ..041 and P = 0.012, respectively). A score based on CD4+ cell counts at nadir, at baseline, at week 2 of treatment interruption, and on baseline HIV-DNA values can identify patients with a prolonged period free safely of treatment...
  59. ncbi request reprint Clearance of human herpesvirus 8 from blood and regression of leukopenia-associated aggressive classic Kaposi's sarcoma during interferon-alpha therapy: a case report
    P Monini
    Laboratory of Virology, , Rome, Italy
    Clin Infect Dis 33:1782-5. 2001
    ..These results suggest a direct relationship between HHV-8 clearance from blood and regression of Kaposi's sarcoma and are consistent with the in vitro inhibitory effects of interferon-alpha on HHV-8 infection...
  60. pmc Correlation between enzyme-linked immunosorbent assay and immunofluorescence assay with lytic antigens for detection of antibodies to human herpesvirus 8
    S Topino
    Department of Clinical Immunology, University of Rome La Sapienza, Rome, Italy
    Clin Diagn Lab Immunol 8:203-5. 2001
    ..The methods showed a stringent correlation, r = 0.625 (P<0.001)...
  61. pmc Interleukin-15 production by monocyte-derived dendritic cells and T cell proliferation in HIV-infected patients with discordant response to highly active antiretroviral therapy
    G d'Ettorre
    Department of Infectious and Tropical Diseases, La Sapienza University, Rome, Italy
    Clin Exp Immunol 135:280-5. 2004
    ....
  62. ncbi request reprint Prevalence, incidence and correlates of HHV-8/KSHV infection and Kaposi's sarcoma in renal and liver transplant recipients
    M Andreoni
    Infectious Disease Clinic, Tor Vergata University, S. Eugenio Hospital, Rome, Italy
    J Infect 43:195-9. 2001
    ..However, renal transplant recipients tend to have a higher risk of KS. HHV-8/KSHV reactivation appears to play a greater role on the risk of KS than incident infections...
  63. ncbi request reprint Viral phenotype and fitness
    M Andreoni
    Department of Public Health, University Tor Vergata Rome, Italy
    New Microbiol 27:71-6. 2004
    ....
  64. ncbi request reprint Incidence of Kaposi's sarcoma and HHV-8 seroprevalence among homosexual men with known dates of HIV seroconversion. Italian Seroconversion Study
    G Rezza
    Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanita, Rome, Italy
    AIDS 14:1647-53. 2000
    ..To evaluate temporal trends of Kaposi's sarcoma (KS) and of the KS-related human herpesvirus (HHV-8) among homosexual men who seroconverted for HIV between 1984 and 1997...
  65. doi request reprint Raltegravir plasma concentrations in treatment-experienced patients receiving salvage regimens based on raltegravir with and without maraviroc coadministration
    Silvia Baroncelli
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
    Ann Pharmacother 44:838-43. 2010
    ..The safety and efficacy of both drugs have been investigated, but there is no information on possible pharmacokinetic interactions between these 2 drugs in clinical practice...
  66. doi request reprint Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy
    A Antinori
    Istituto Nazionale Malattie Infettive Lazzaro Spallanzani IRCCS, Via Portuense 292, 00149, Rome, Italy
    Infection 37:270-82. 2009
    ..Infection management in such patients can also be complicated by underlying conditions, comorbidities, and the need for concomitant medications...
  67. pmc HIV coreceptor tropism in paired plasma, peripheral blood mononuclear cell, and cerebrospinal fluid isolates from antiretroviral-naïve subjects
    S G Parisi
    Department of Histology, Microbiology and Medical Biotechnologies, Padua University, Padua, Italy
    J Clin Microbiol 49:1441-5. 2011
    ....
  68. ncbi request reprint Two-year surveillance on fluconazole susceptibility of Candida spp isolates in a general and university hospital in Rome
    G P Testore
    University of Rome Tor Vergata, Department of Public Health, Rome, Italy
    Diagn Microbiol Infect Dis 41:23-7. 2001
    ..Fluconazole maintained a good activity against Candida spp despite its extensive use for the prophylaxis and treatment of fungal infections...
  69. ncbi request reprint NK cell activity controls human herpesvirus 8 latent infection and is restored upon highly active antiretroviral therapy in AIDS patients with regressing Kaposi's sarcoma
    Maria Caterina Sirianni
    Department of Clinical Immunology, University of Rome La Sapienza, Viale dell Universita 37, I 00185 Rome, Italy
    Eur J Immunol 32:2711-20. 2002
    ..These results suggest a key role for NK cells in the control of HHV8 latent infection, KS development, and in disease remission upon HAART...
  70. ncbi request reprint Human herpesvirus 8 cytoviraemia rebound in a patient with Kaposi's sarcoma after a short interruption of efficient antiretroviral therapy
    Saverio Giuseppe Parisi
    AIDS 16:1089-91. 2002
  71. ncbi request reprint Does the risk of abortion increase in women with high human herpesvirus-8 antibody titers?
    Loredana Sarmati
    J Infect Dis 188:173-4; author reply 174-5. 2003
  72. pmc Calibrated real-time PCR assay for quantitation of human herpesvirus 8 DNA in biological fluids
    Francesco Broccolo
    Unit of Human Virology, DIBIT, San Raffele Scientific Institute, 20132 Milan, Italy
    J Clin Microbiol 40:4652-8. 2002
    ..In conclusion, our calibrated real-time PCR assay provides a reliable high-throughput method for quantitation of HHV-8 DNA in clinical and laboratory specimens...
  73. ncbi request reprint Prevalence trend and correlates of HHV-8 infection in HIV-infected patients
    Saverio Giuseppe Parisi
    Institute of Immunology and Infectious Diseases, University of Verona, Italy
    J Acquir Immune Defic Syndr 29:295-9. 2002
    ..In conclusion, HHV-8 seroprevalence appears to be increased during 10 years among HIV-infected injection drug users but not among homosexual men, who remain those at the highest risk of infection...
  74. pmc Identification of cytotoxic T lymphocyte epitopes of human herpesvirus 8
    Fabiola Micheletti
    Department of Biochemistry and Molecular Biology, University of Ferrara, Italy
    Immunology 106:395-403. 2002
    ..The identified epitopes may be investigated for the development of immunotherapeutic strategies against HHV-8-associated malignancies...
  75. ncbi request reprint Retrospective analysis of HHV-8 viremia and cellular viral load in HIV-seropositive patients receiving interleukin 2 in combination with antiretroviral therapy
    Mauro Malnati
    Unit of Human Virology, AIDS Immunopathogenesis Unit, San Raffaele Scientific Institute, Milan, Italy
    Blood 100:1575-8. 2002
    ..Thus, IL-2 therapy seems safe in most patients infected with both HIV and HHV-8, except for those with detectable HHV-8 viremia, who may not be eligible for IL-2 treatment...
  76. ncbi request reprint Long-term follow-up of previous hepatitis C virus positive nonresponders to interferon monotherapy successfully retreated with combination therapy: are they really cured?
    Alessia Ciancio
    Dipartimento di Gastroenterologia, Ospedale Molinette, Torino, Italy
    Am J Gastroenterol 101:1811-6. 2006
    ....
  77. pmc Both human immunodeficiency virus cellular DNA sequencing and plasma RNA sequencing are useful for detection of drug resistance mutations in blood samples from antiretroviral-drug-naive patients
    Saverio G Parisi
    Department of Histology, Microbiology and Medical Biotechnology, Padova University, Via Gabelli 63, 35100 Padova, Italy
    J Clin Microbiol 45:1783-8. 2007
    ..0% and 36.2% of the subjects, respectively. Our data support the potential utility of genotypic resistance testing of PBMC DNA in conjunction with the currently recommended plasma RNA analysis...
  78. ncbi request reprint HIV-1 residual viremia and proviral DNA in patients with suppressed plasma viral load (<400 HIV-RNA cp/ml) during different antiretroviral regimens
    Emanuele Nicastri
    Istituto Nazionale per le Malattie Infettive IRCCS Lazzaro Spallanzani Rome, Italy
    Curr HIV Res 6:261-6. 2008
    ..The better virological performance of NNRTI in terms of low residual viremia is consistent with specific literature data, whereas the greater impact of PI on the viral reservoirs is noteworthy and needs further investigations...