Marcello Massimini

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. doi request reprint A perturbational approach for evaluating the brain's capacity for consciousness
    Marcello Massimini
    Department of Clinical Sciences, University of Milan, Milan, Italy
    Prog Brain Res 177:201-14. 2009
  2. pmc Recovery of cortical effective connectivity and recovery of consciousness in vegetative patients
    Mario Rosanova
    Department of Clinical Sciences Luigi Sacco, University of Milan, 20157 Milan, Italy
    Brain 135:1308-20. 2012
  3. pmc EEG responses to TMS are sensitive to changes in the perturbation parameters and repeatable over time
    Silvia Casarotto
    Department of Clinical Sciences L Sacco, Universita degli Studi di Milano, Milan, Italy
    PLoS ONE 5:e10281. 2010
  4. doi request reprint Time-frequency spectral analysis of TMS-evoked EEG oscillations by means of Hilbert-Huang transform
    Andrea Pigorini
    Department of Clinical Sciences Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
    J Neurosci Methods 198:236-45. 2011
  5. doi request reprint Natural frequencies of human corticothalamic circuits
    Mario Rosanova
    Department of Clinical Sciences, Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
    J Neurosci 29:7679-85. 2009
  6. pmc Assessing the effects of electroconvulsive therapy on cortical excitability by means of transcranial magnetic stimulation and electroencephalography
    Silvia Casarotto
    Department of Biomedical and Clinical Sciences L Sacco, Universita degli Studi di Milano, Via G B Grassi, 74, 20157, Milan, Italy
    Brain Topogr 26:326-37. 2013
  7. pmc Human cortical excitability increases with time awake
    Reto Huber
    Department of Clinical Sciences Luigi Sacco, Universita degli Studi di Milano, 20157 Milan, Italy
    Cereb Cortex 23:332-8. 2013
  8. doi request reprint A theoretically based index of consciousness independent of sensory processing and behavior
    Adenauer G Casali
    Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, 20157 Milan, Italy
    Sci Transl Med 5:198ra105. 2013
  9. doi request reprint General indices to characterize the electrical response of the cerebral cortex to TMS
    Adenauer G Casali
    Department of Clinical Sciences, Universita degli Studi di Milano, Via GB Grassi 74, 20157 Milan, Italy
    Neuroimage 49:1459-68. 2010
  10. ncbi request reprint EEG slow (approximately 1 Hz) waves are associated with nonstationarity of thalamo-cortical sensory processing in the sleeping human
    Marcello Massimini
    Department of Clinical Science, Osp L Sacco, Faculty of Medicine, University of Milan, 20157 Milan, Italy
    J Neurophysiol 89:1205-13. 2003

Collaborators

Detail Information

Publications12

  1. doi request reprint A perturbational approach for evaluating the brain's capacity for consciousness
    Marcello Massimini
    Department of Clinical Sciences, University of Milan, Milan, Italy
    Prog Brain Res 177:201-14. 2009
    ..Based on these results, we discuss the potential applications of this novel technique to evaluate objectively the brain's capacity for consciousness at the bedside of brain-injured patients...
  2. pmc Recovery of cortical effective connectivity and recovery of consciousness in vegetative patients
    Mario Rosanova
    Department of Clinical Sciences Luigi Sacco, University of Milan, 20157 Milan, Italy
    Brain 135:1308-20. 2012
    ....
  3. pmc EEG responses to TMS are sensitive to changes in the perturbation parameters and repeatable over time
    Silvia Casarotto
    Department of Clinical Sciences L Sacco, Universita degli Studi di Milano, Milan, Italy
    PLoS ONE 5:e10281. 2010
    ....
  4. doi request reprint Time-frequency spectral analysis of TMS-evoked EEG oscillations by means of Hilbert-Huang transform
    Andrea Pigorini
    Department of Clinical Sciences Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
    J Neurosci Methods 198:236-45. 2011
    ..These results suggest that the HHT-based algorithm may be used to study the communication between different cortical oscillators on a fine time scale...
  5. doi request reprint Natural frequencies of human corticothalamic circuits
    Mario Rosanova
    Department of Clinical Sciences, Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
    J Neurosci 29:7679-85. 2009
    ..The natural frequency can be directly measured in virtually any area of the cerebral cortex and may represent a straightforward and flexible way to probe the state of human thalamocortical circuits at the patient's bedside...
  6. pmc Assessing the effects of electroconvulsive therapy on cortical excitability by means of transcranial magnetic stimulation and electroencephalography
    Silvia Casarotto
    Department of Biomedical and Clinical Sciences L Sacco, Universita degli Studi di Milano, Via G B Grassi, 74, 20157, Milan, Italy
    Brain Topogr 26:326-37. 2013
    ..To the extent that depression involves an alteration of frontal cortical excitability, these measurements may be used to guide and evaluate treatment progression over time at the single-patient level...
  7. pmc Human cortical excitability increases with time awake
    Reto Huber
    Department of Clinical Sciences Luigi Sacco, Universita degli Studi di Milano, 20157 Milan, Italy
    Cereb Cortex 23:332-8. 2013
    ..The present results provide noninvasive electrophysiological evidence that wakefulness is associated with a steady increase in the excitability of human cortical circuits that is rebalanced during sleep...
  8. doi request reprint A theoretically based index of consciousness independent of sensory processing and behavior
    Adenauer G Casali
    Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, 20157 Milan, Italy
    Sci Transl Med 5:198ra105. 2013
    ..PCI can potentially be used for objective determination of the level of consciousness at the bedside. ..
  9. doi request reprint General indices to characterize the electrical response of the cerebral cortex to TMS
    Adenauer G Casali
    Department of Clinical Sciences, Universita degli Studi di Milano, Via GB Grassi 74, 20157 Milan, Italy
    Neuroimage 49:1459-68. 2010
    ..These general indices may be used to characterize the effects of TMS on any cortical area and to quantitatively evaluate cortical excitability and connectivity in physiological and pathological conditions...
  10. ncbi request reprint EEG slow (approximately 1 Hz) waves are associated with nonstationarity of thalamo-cortical sensory processing in the sleeping human
    Marcello Massimini
    Department of Clinical Science, Osp L Sacco, Faculty of Medicine, University of Milan, 20157 Milan, Italy
    J Neurophysiol 89:1205-13. 2003
    ..The present findings demonstrate that thalamo-cortical processing of sensory information is not stationary in the very short period (approximately 500 ms) during natural SWS...
  11. doi request reprint Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging
    Silvia Casarotto
    Department of Clinical Sciences L Sacco Università degli Studi di Milano, Milan, Italy
    Neuroreport 22:592-7. 2011
    ..We have shown that the EEG response to TMS of the left superior frontal cortex is not affected by physiological aging but is markedly altered by cognitive impairment...
  12. doi request reprint Augmentative repetitive navigated transcranial magnetic stimulation (rTMS) in drug-resistant bipolar depression
    Bernardo Dell'Osso
    Department of Psychiatry, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena Milano, Italy
    Bipolar Disord 11:76-81. 2009
    ..The present study aimed to assess the efficacy of low-frequency repetitive TMS (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) combined with brain navigation in a sample of bipolar depressed subjects...