Affiliation: University of Milan
- A perturbational approach for evaluating the brain's capacity for consciousnessMarcello Massimini
Department of Clinical Sciences, University of Milan, Milan, Italy
Prog Brain Res 177:201-14. 2009..Based on these results, we discuss the potential applications of this novel technique to evaluate objectively the brain's capacity for consciousness at the bedside of brain-injured patients...
- EEG responses to TMS are sensitive to changes in the perturbation parameters and repeatable over timeSilvia Casarotto
Department of Clinical Sciences L Sacco, Universita degli Studi di Milano, Milan, Italy
PLoS ONE 5:e10281. 2010....
- Assessing the effects of electroconvulsive therapy on cortical excitability by means of transcranial magnetic stimulation and electroencephalographySilvia Casarotto
Department of Biomedical and Clinical Sciences L Sacco, Universita degli Studi di Milano, Via G B Grassi, 74, 20157, Milan, Italy
Brain Topogr 26:326-37. 2013..To the extent that depression involves an alteration of frontal cortical excitability, these measurements may be used to guide and evaluate treatment progression over time at the single-patient level...
- Recovery of cortical effective connectivity and recovery of consciousness in vegetative patientsMario Rosanova
Department of Clinical Sciences Luigi Sacco, University of Milan, 20157 Milan, Italy
Brain 135:1308-20. 2012....
- Quantifying cortical EEG responses to TMS in (un)consciousnessSimone Sarasso
Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy
Clin EEG Neurosci 45:40-9. 2014..Finally, we will underline some crucial methodological aspects concerning TMS/EEG measurements of brain complexity. ..
- Natural frequencies of human corticothalamic circuitsMario Rosanova
Department of Clinical Sciences, Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
J Neurosci 29:7679-85. 2009..The natural frequency can be directly measured in virtually any area of the cerebral cortex and may represent a straightforward and flexible way to probe the state of human thalamocortical circuits at the patient's bedside...
- A theoretically based index of consciousness independent of sensory processing and behaviorAdenauer G Casali
Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, 20157 Milan, Italy
Sci Transl Med 5:198ra105. 2013..PCI can potentially be used for objective determination of the level of consciousness at the bedside. ..
- General indices to characterize the electrical response of the cerebral cortex to TMSAdenauer G Casali
Department of Clinical Sciences, Universita degli Studi di Milano, Via GB Grassi 74, 20157 Milan, Italy
Neuroimage 49:1459-68. 2010..These general indices may be used to characterize the effects of TMS on any cortical area and to quantitatively evaluate cortical excitability and connectivity in physiological and pathological conditions...
- Time-frequency spectral analysis of TMS-evoked EEG oscillations by means of Hilbert-Huang transformAndrea Pigorini
Department of Clinical Sciences Luigi Sacco, Universita degli Studi di Milano, Milan, Italy
J Neurosci Methods 198:236-45. 2011..These results suggest that the HHT-based algorithm may be used to study the communication between different cortical oscillators on a fine time scale...
- Human cortical excitability increases with time awakeReto Huber
Department of Clinical Sciences Luigi Sacco, Universita degli Studi di Milano, 20157 Milan, Italy
Cereb Cortex 23:332-8. 2013..The present results provide noninvasive electrophysiological evidence that wakefulness is associated with a steady increase in the excitability of human cortical circuits that is rebalanced during sleep...
- EEG slow (approximately 1 Hz) waves are associated with nonstationarity of thalamo-cortical sensory processing in the sleeping humanMarcello Massimini
Department of Clinical Science, Osp L Sacco, Faculty of Medicine, University of Milan, 20157 Milan, Italy
J Neurophysiol 89:1205-13. 2003..The present findings demonstrate that thalamo-cortical processing of sensory information is not stationary in the very short period (approximately 500 ms) during natural SWS...
- Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological agingSilvia Casarotto
Department of Clinical Sciences L Sacco Università degli Studi di Milano, Milan, Italy
Neuroreport 22:592-7. 2011..We have shown that the EEG response to TMS of the left superior frontal cortex is not affected by physiological aging but is markedly altered by cognitive impairment...
- Augmentative repetitive navigated transcranial magnetic stimulation (rTMS) in drug-resistant bipolar depressionBernardo Dell'Osso
Department of Psychiatry, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena Milano, Italy
Bipolar Disord 11:76-81. 2009..The present study aimed to assess the efficacy of low-frequency repetitive TMS (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) combined with brain navigation in a sample of bipolar depressed subjects...