Margherita Massa

Summary

Affiliation: University of Pavia
Country: Italy

Publications

  1. ncbi request reprint Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction
    Margherita Massa
    Biotechnology Laboratory, Department of Cardiology, Internal Medicine and Mecical Oncology, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    Blood 105:199-206. 2005
  2. pmc JAK2 V617F genotype is a strong determinant of blast transformation in primary myelofibrosis
    Giovanni Barosi
    Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    PLoS ONE 8:e59791. 2013
  3. pmc A3669G polymorphism of glucocorticoid receptor is a susceptibility allele for primary myelofibrosis and contributes to phenotypic diversity and blast transformation
    Valentina Poletto
    Unit of Clinical Epidemiology, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    Blood 120:3112-7. 2012
  4. doi request reprint Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation
    Vittorio Rosti
    Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Policlinico San Matteo Foundation, Viale Golgi 19, Pavia, Italy
    Blood 121:360-8. 2013
  5. pmc Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis
    Stefania Badalucco
    Biotechnology Laboratories, Department of Molecular Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
    Haematologica 98:514-7. 2013
  6. pmc Evidence that prefibrotic myelofibrosis is aligned along a clinical and biological continuum featuring primary myelofibrosis
    Giovanni Barosi
    Laboratory of Clinical Epidemiology and Centre for the Study of Myelofibrosis, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    PLoS ONE 7:e35631. 2012
  7. pmc High frequency of endothelial colony forming cells marks a non-active myeloproliferative neoplasm with high risk of splanchnic vein thrombosis
    Vittorio Rosti
    Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    PLoS ONE 5:e15277. 2010
  8. doi request reprint High-dose erythropoietin in patients with acute myocardial infarction: a pilot, randomised, placebo-controlled study
    Maurizio Ferrario
    Cardiology Department, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Int J Cardiol 147:124-31. 2011
  9. doi request reprint Evaluation of the bioactive and total transforming growth factor β1 levels in primary myelofibrosis
    Rita Campanelli
    Laboratory of Clinical Epidemiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Cytokine 53:100-6. 2011
  10. ncbi request reprint Early haemoglobin-independent increase of plasma erythropoietin levels in patients with acute myocardial infarction
    Maurizio Ferrario
    Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, P le Golgi 2, 27100 Pavia, Italy
    Eur Heart J 28:1805-13. 2007

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction
    Margherita Massa
    Biotechnology Laboratory, Department of Cardiology, Internal Medicine and Mecical Oncology, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    Blood 105:199-206. 2005
    ..05). No significant difference was documented between patients with SA and CTRLs. Spontaneous mobilization of both HPCs and EPCs occurs within a few hours from the onset of AMI and is detectable until 2 months...
  2. pmc JAK2 V617F genotype is a strong determinant of blast transformation in primary myelofibrosis
    Giovanni Barosi
    Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    PLoS ONE 8:e59791. 2013
    ..In a large cohort of patients we applied competing risks analysis for studying the influence of JAK2V617F mutation on BT in PMF...
  3. pmc A3669G polymorphism of glucocorticoid receptor is a susceptibility allele for primary myelofibrosis and contributes to phenotypic diversity and blast transformation
    Valentina Poletto
    Unit of Clinical Epidemiology, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    Blood 120:3112-7. 2012
    ..3; P = .006). In conclusion, the glucocorticoid receptor A3669G is a susceptibility allele for PMF: it contributes to confer the phenotype of excess myeloproliferation, and it cooperates with the JAK2V617F mutation in determining BT...
  4. doi request reprint Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation
    Vittorio Rosti
    Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Policlinico San Matteo Foundation, Viale Golgi 19, Pavia, Italy
    Blood 121:360-8. 2013
    ..In conclusion, we provide evidence that some ECs from the spleen and splenic veins of patients with MF bear the JAK2V617F mutation. We suggest that splenic ECs are involved in the process of malignant transformation in MF...
  5. pmc Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis
    Stefania Badalucco
    Biotechnology Laboratories, Department of Molecular Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
    Haematologica 98:514-7. 2013
    ..Despite the increase in Transforming Growth Factor β1 this mechanism seems to be preserved in primary myelofibrosis...
  6. pmc Evidence that prefibrotic myelofibrosis is aligned along a clinical and biological continuum featuring primary myelofibrosis
    Giovanni Barosi
    Laboratory of Clinical Epidemiology and Centre for the Study of Myelofibrosis, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    PLoS ONE 7:e35631. 2012
    ..In the WHO diagnostic classification, prefibrotic myelofibrosis (pre-MF) is included in the category of primary myelofibrosis (PMF). However, strong evidence for this position is lacking...
  7. pmc High frequency of endothelial colony forming cells marks a non-active myeloproliferative neoplasm with high risk of splanchnic vein thrombosis
    Vittorio Rosti
    Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    PLoS ONE 5:e15277. 2010
    ..Due to inherent performance limitations of ECFCs assay, there is an urgent need to arrive to an acceptable standardization of ECFC assessment...
  8. doi request reprint High-dose erythropoietin in patients with acute myocardial infarction: a pilot, randomised, placebo-controlled study
    Maurizio Ferrario
    Cardiology Department, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Int J Cardiol 147:124-31. 2011
    ..Mortality and morbidity after acute myocardial infarction (AMI) remain high even when myocardial reperfusion is successful. Erythropoietin (EPO) protects against experimental MI...
  9. doi request reprint Evaluation of the bioactive and total transforming growth factor β1 levels in primary myelofibrosis
    Rita Campanelli
    Laboratory of Clinical Epidemiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Cytokine 53:100-6. 2011
    ....
  10. ncbi request reprint Early haemoglobin-independent increase of plasma erythropoietin levels in patients with acute myocardial infarction
    Maurizio Ferrario
    Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, P le Golgi 2, 27100 Pavia, Italy
    Eur Heart J 28:1805-13. 2007
    ....
  11. ncbi request reprint Spleen neoangiogenesis in patients with myelofibrosis with myeloid metaplasia
    Giovanni Barosi
    Laboratory of Medical Informatics, IRCCS Policlinico S Matteo, Viale Golgi 19, 27100 Pavia, Italy
    Br J Haematol 124:618-25. 2004
    ..These results document that neoangiogenesis is an integral component of spleen re-localization of haematopoietic stem cells and suggest a cellular mechanism for spleen neoangiogenesis...
  12. pmc Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients
    Francesco Lodola
    Department of Biology and Biotechnology Lazzaro Spallanzani, University of Pavia, Pavia, Italy
    PLoS ONE 7:e42541. 2012
    ..As oncogenesis may be associated to the capability of tumor cells to grow independently on Ca(2+) influx, it is important to assess whether SOCE regulates EPC-dependent angiogenesis also in tumor patients...
  13. ncbi request reprint JAK2 V617F mutational status predicts progression to large splenomegaly and leukemic transformation in primary myelofibrosis
    Giovanni Barosi
    Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Policlinico S Matteo Foundation, Pavia, Italy
    Blood 110:4030-6. 2007
    ..We conclude that JAK2 V617F genotype should be considered in any future risk stratification of patients with PMF...
  14. ncbi request reprint Increased expression of alpha(1,3)-fucosyltransferase-VII and P-selectin binding of synovial fluid T cells in juvenile idiopathic arthritis
    Fabrizio De Benedetti
    Pediatria Generale e Reumatologia, Dipartimento di Pediatria, IRCCS Policlinico San Matteo, Pavia, Italy
    J Rheumatol 30:1611-5. 2003
    ..Here, we focus on alpha(1,3)-fucosyltransferase-VII (FucT-VII), an enzyme responsible for the generation of functional P- and E-selectin ligands that is upregulated in Th1 cells...
  15. ncbi request reprint Vascular endothelial growth factor promoted endothelial progenitor cell mobilization into the peripheral blood of a patient with POEMS syndrome
    Vittorio Rosti
    Haematologica 92:1291-2. 2007
    ..In vitro cultures of the patient BM cells suggested that the stromal compartment could be responsible for VEGF overproduction...
  16. ncbi request reprint The expression of CXCR4 is down-regulated on the CD34+ cells of patients with myelofibrosis with myeloid metaplasia
    Vittorio Rosti
    Transplant Research Area, IRCCS Policlinico S Matteo, Viale Golgi 19, 27100 Pavia, Italy
    Blood Cells Mol Dis 38:280-6. 2007
    ..We studied the expression of the chemokine receptor CXCR4 on circulating CD34+ cells of patients with myelofibrosis with myeloid metaplasia (MMM), and examined its relationship to the severity of disease...
  17. ncbi request reprint Circulating CD34+, CD133+, and vascular endothelial growth factor receptor 2-positive endothelial progenitor cells in myelofibrosis with myeloid metaplasia
    Margherita Massa
    Laboratory of Biotechnology, Italy
    J Clin Oncol 23:5688-95. 2005
    ..We measured the number of circulating EPCs in patients with myelofibrosis with myeloid metaplasia (MMM), and we examined the relationship between the number of EPCs and severity of the MMM disease process...
  18. ncbi request reprint Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis
    Sylvia Kamphuis
    Department of Paediatric Immunology, IACOPO Institute for Translational Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands
    Lancet 366:50-6. 2005
    ..We sought to identify HSP60 T-cell epitopes to find potential targets for HSP60 immunotherapy and to assess whether immune responses to these epitopes contribute to the distinct clinical outcome of this disease...
  19. ncbi request reprint Does gabexate mesilate affect serum concentrations of acute phase proteins after endoscopic retrograde cholangiopancreatography examination?
    Raffaele Pezzilli
    Department of Internal Medicine, Azienda Ospedaliera Policlinico S Orsola Malpighi, Bologna, Italy
    Hepatogastroenterology 50:851-5. 2003
    ..To explore the possibility that the preventive effect of gabexate mesilate on endoscopic retrograde cholangiopancreatography-related acute pancreatitis may be mediated by its modulation of acute phase proteins...
  20. ncbi request reprint Genetic immunization maps T cell (auto)immune responses to self antigens homologous to exogenous proteins
    Antonio La Cava
    Department of Medicine, University of California, San Diego, La Jolla 92093 0663, USA
    Autoimmunity 35:105-10. 2002
    ..Furthermore, preferential secretion of Th1-type pro-inflammatory cytokines occurred. This strategy can allow rapid screening of interactive immune networks involving aminoacid sequence homologies between organisms...