Emanuela Maserati

Summary

Affiliation: University of Insubria
Country: Italy

Publications

  1. pmc Chromosome anomalies in bone marrow as primary cause of aplastic or hypoplastic conditions and peripheral cytopenia: disorders due to secondary impairment of RUNX1 and MPL genes
    Cristina Marletta
    Biologia e Genetica, Dipartimento di Medicina Clinica e Sperimentale, Università dell lnsubria, Varese, Italy
    Mol Cytogenet 5:39. 2012
  2. pmc Comparative genomic hybridization on microarray (a-CGH) in constitutional and acquired mosaicism may detect as low as 8% abnormal cells
    Roberto Valli
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, Varese, Italy
    Mol Cytogenet 4:13. 2011
  3. doi request reprint The route to development of myelodysplastic syndrome/acute myeloid leukaemia in Shwachman-Diamond syndrome: the role of ageing, karyotype instability, and acquired chromosome anomalies
    Emanuela Maserati
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Università dell lnsubria, Varese, Italy
    Br J Haematol 145:190-7. 2009
  4. ncbi request reprint Trisomy 8 in myelodysplasia and acute leukemia is constitutional in 15-20% of cases
    Emanuela Maserati
    Sezione di Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, via J H Dunant 5, I 21100 Varese, Italy
    Genes Chromosomes Cancer 33:93-7. 2002
  5. ncbi request reprint Shwachman syndrome as mutator phenotype responsible for myeloid dysplasia/neoplasia through karyotype instability and chromosomes 7 and 20 anomalies
    Emanuela Maserati
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Università dell lnsubria, Varese, Italy
    Genes Chromosomes Cancer 45:375-82. 2006
  6. ncbi request reprint Monitoring the isochromosome i(7)(q10) in the bone marrow of patients with Shwachman syndrome by real-time quantitative PCR
    Giovanni Porta
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, Varese, Italy
    J Pediatr Hematol Oncol 29:163-5. 2007
  7. ncbi request reprint Familial myelodysplastic syndromes, monosomy 7/trisomy 8, and mutator effects
    Emanuela Maserati
    Sezione di Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    Cancer Genet Cytogenet 148:155-8. 2004
  8. doi request reprint Evaluating chromosomal mosaicism by array comparative genomic hybridization in hematological malignancies: the proposal of a formula
    Roberto Valli
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, Varese, Italy
    Cancer Genet 204:216-8. 2011
  9. doi request reprint Patau syndrome with long survival in a case of unusual mosaic trisomy 13
    Giuseppina Fogu
    Clinical Genetics, Department of Biomedical Sciences, University of Sassari, Viale San Pietro, 43 C, 07100 Sassari, Italy
    Eur J Med Genet 51:303-14. 2008
  10. ncbi request reprint MLL-MLLT10 fusion in acute monoblastic leukemia: variant complex rearrangements and 11q proximal breakpoint heterogeneity
    Cristina Morerio
    Dipartimento di Ematologia ed Oncologia Pediatrica, Istituto Giannina Gaslini, L go G Gaslini 5, 16148 Genova, Italy
    Cancer Genet Cytogenet 152:108-12. 2004

Collaborators

  • Marco Zecca
  • Simona Ferrari
  • Fabrizio Vinante
  • F Locatelli
  • C L Balduini
  • Giampiero Beluffi
  • Giuseppina Fogu
  • Francesco Pasquali
  • Roberto Valli
  • Francesco Lo Curto
  • Cristina Marletta
  • Barbara Pressato
  • Cristina Morerio
  • Claudio Panarello
  • Giuseppe Montalbano
  • Maria Ester Bernardo
  • Giovanni Porta
  • Cristina Rosanda
  • Annamaria Rapella
  • Antonella Minelli
  • Cesare Danesino
  • Carla Olivieri
  • Luciana Vinti
  • Lydia Mare
  • Giuseppe Menna
  • Alessandra Di Cesare-Merlone
  • Giuseppe Loffredo
  • Elia Mattarucchi
  • Anna Leszl
  • Maura Acquila
  • Carlo Dufour
  • Laura Sainati
  • Piero De Stefano
  • Paolo Pierani
  • Gabriele Rossi
  • Luca Lo Nigro
  • Maria Paola Cecchini
  • Edoardo Lanino
  • Andrea Di Cataldo
  • Veronica Albano
  • Desiree Caselli
  • Carla Martini
  • Paola Maraschio

Detail Information

Publications16

  1. pmc Chromosome anomalies in bone marrow as primary cause of aplastic or hypoplastic conditions and peripheral cytopenia: disorders due to secondary impairment of RUNX1 and MPL genes
    Cristina Marletta
    Biologia e Genetica, Dipartimento di Medicina Clinica e Sperimentale, Università dell lnsubria, Varese, Italy
    Mol Cytogenet 5:39. 2012
    ..abstract:..
  2. pmc Comparative genomic hybridization on microarray (a-CGH) in constitutional and acquired mosaicism may detect as low as 8% abnormal cells
    Roberto Valli
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, Varese, Italy
    Mol Cytogenet 4:13. 2011
    ....
  3. doi request reprint The route to development of myelodysplastic syndrome/acute myeloid leukaemia in Shwachman-Diamond syndrome: the role of ageing, karyotype instability, and acquired chromosome anomalies
    Emanuela Maserati
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Università dell lnsubria, Varese, Italy
    Br J Haematol 145:190-7. 2009
    ....
  4. ncbi request reprint Trisomy 8 in myelodysplasia and acute leukemia is constitutional in 15-20% of cases
    Emanuela Maserati
    Sezione di Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, via J H Dunant 5, I 21100 Varese, Italy
    Genes Chromosomes Cancer 33:93-7. 2002
    ..A few clinical signs of CT8M were also present in these three patients. Our data indicate that the frequency of CT8M in hematological dysplastic and neoplastic disorders with trisomy 8 is approximately 15-20%...
  5. ncbi request reprint Shwachman syndrome as mutator phenotype responsible for myeloid dysplasia/neoplasia through karyotype instability and chromosomes 7 and 20 anomalies
    Emanuela Maserati
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Università dell lnsubria, Varese, Italy
    Genes Chromosomes Cancer 45:375-82. 2006
    ..This conclusion supports the practice of including cytogenetic monitoring in the follow-up of SS patients...
  6. ncbi request reprint Monitoring the isochromosome i(7)(q10) in the bone marrow of patients with Shwachman syndrome by real-time quantitative PCR
    Giovanni Porta
    Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, Varese, Italy
    J Pediatr Hematol Oncol 29:163-5. 2007
    ..As the results obtained by RQ-PCR refer to the DNA of around 128,000 BM cells, our method proved to be feasible and more efficient in the quantitative evaluation of the i(7)(q10)-positive clone than conventional ones...
  7. ncbi request reprint Familial myelodysplastic syndromes, monosomy 7/trisomy 8, and mutator effects
    Emanuela Maserati
    Sezione di Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, via J H Dunant 5, 21100 Varese, Italy
    Cancer Genet Cytogenet 148:155-8. 2004
    ..We postulate that in these families an inherited mutator effect is present and that it causes a karyotype instability, which leads to MDS/AML, often through the acquisition of monosomy 7 and trisomy 8...
  8. doi request reprint Evaluating chromosomal mosaicism by array comparative genomic hybridization in hematological malignancies: the proposal of a formula
    Roberto Valli
    Biologia e Genetica, Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita dell Insubria, Varese, Italy
    Cancer Genet 204:216-8. 2011
    ..Although some approximation affects both the results inferred from aCGH and FISH data, the proposed formula was successful in the three patients studied...
  9. doi request reprint Patau syndrome with long survival in a case of unusual mosaic trisomy 13
    Giuseppina Fogu
    Clinical Genetics, Department of Biomedical Sciences, University of Sassari, Viale San Pietro, 43 C, 07100 Sassari, Italy
    Eur J Med Genet 51:303-14. 2008
    ..Cytogenetic findings of the chromosomal analyses on different tissues, including skin fibroblasts from differently pigmented areas, are also reported...
  10. ncbi request reprint MLL-MLLT10 fusion in acute monoblastic leukemia: variant complex rearrangements and 11q proximal breakpoint heterogeneity
    Cristina Morerio
    Dipartimento di Ematologia ed Oncologia Pediatrica, Istituto Giannina Gaslini, L go G Gaslini 5, 16148 Genova, Italy
    Cancer Genet Cytogenet 152:108-12. 2004
    ..We review the cytogenetic molecular data concerning the proximal inversion breakpoint of 11q and confirm its heterogeneity...
  11. ncbi request reprint Familial platelet disorder with propensity to acute myelogenous leukemia: genetic heterogeneity and progression to leukemia via acquisition of clonal chromosome anomalies
    Antonella Minelli
    Biologia Generale e Genetica Medica, Universita di Pavia, Pavia, Italy
    Genes Chromosomes Cancer 40:165-71. 2004
    ....
  12. ncbi request reprint Constitutional trisomy 8 mosaicism in primary myelofibrosis: relevance to clinical practice and warning for trisomy 8 studies
    Emanuela Maserati
    Cancer Genet Cytogenet 179:79-81. 2007
  13. ncbi request reprint HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2)
    Cristina Morerio
    Dipartimento di Ematologia ed Oncologia Pediatrica, Istituto di Ricovero e Cura a Carattere Scientifico Istituto G Gaslini, Genova, Italy
    Cancer Res 64:2649-51. 2004
    ..We show that the breakpoint of PDGFRB occurred at the same site of all previously reported PDGFRB translocations...
  14. doi request reprint Clonal chromosome anomalies and propensity to myeloid malignancies in congenital amegakaryocytic thrombocytopenia (OMIM 604498)
    Emanuela Maserati
    Haematologica 93:1271-3. 2008
  15. ncbi request reprint Minimal residual disease and trisomy 8
    Francesco Pasquali
    Cancer Genet Cytogenet 140:176. 2003
  16. ncbi request reprint Interstitial deletion of chromosome 9, int del(9)(9q22.31-q31.2), including the genes causing multiple basal cell nevus syndrome and Robinow/brachydactyly 1 syndrome
    Carla Olivieri
    Biologia Generale e Genetica Medica, Universita di Pavia, Pavia, Italy
    Eur J Pediatr 162:100-3. 2003
    ..Thus the efforts to identify the genes included in a deletion are worthy as they may result in better care of the patient as, in this case, monitoring the possible development of tumours associated with NBCCS...