Mario Mascalchi

Summary

Affiliation: University of Florence
Country: Italy

Publications

  1. ncbi request reprint Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study
    L Guerrini
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence, Italy
    Brain 127:1785-95. 2004
  2. doi request reprint Low agreement of visual rating for detailed quantification of pulmonary emphysema in whole-lung CT
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Italy
    Acta Radiol 53:53-60. 2012
  3. doi request reprint Changes in volume-corrected whole-lung density in smokers and former smokers during the ITALUNG screening trial
    Mario Mascalchi
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Viale Morgagni 85, Florence, Italy
    J Thorac Imaging 27:255-62. 2012
  4. pmc Dose exposure in the ITALUNG trial of lung cancer screening with low-dose CT
    M Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Br J Radiol 85:1134-9. 2012
  5. doi request reprint Magnetic resonance and nuclear medicine imaging in ataxias
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Italy
    Handb Clin Neurol 103:85-110. 2012
  6. ncbi request reprint Risk-benefit analysis of X-ray exposure associated with lung cancer screening in the Italung-CT trial
    Mario Mascalchi
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Viale Morgagni 85, 50134 Firenze, Italia
    AJR Am J Roentgenol 187:421-9. 2006
  7. doi request reprint Spinocerebellar ataxias
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, 50134 Florence, Italy
    Neurol Sci 29:311-3. 2008
  8. ncbi request reprint Huntington disease: volumetric, diffusion-weighted, and magnetization transfer MR imaging of brain
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology and Department of Neurological Sciences, University of Florence, Viale Morgagni 85, Florence, Italy
    Radiology 232:867-73. 2004
  9. ncbi request reprint Diffusion-weighted MR of the brain: methodology and clinical application
    Mario Mascalchi
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Florence, Italy
    Radiol Med 109:155-97. 2005
  10. ncbi request reprint Early MR imaging and spectroscopy appearance of eIF2B-related leukoencephalopathy
    M Mascalchi
    Radidodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Neurology 67:537-8. 2006

Detail Information

Publications89

  1. ncbi request reprint Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study
    L Guerrini
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence, Italy
    Brain 127:1785-95. 2004
    ....
  2. doi request reprint Low agreement of visual rating for detailed quantification of pulmonary emphysema in whole-lung CT
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Italy
    Acta Radiol 53:53-60. 2012
    ..Multidetector spiral computed tomography (CT) has opened the possibility of quantitative evaluation of emphysema extent in the whole lung. Visual assessment can be used for such a purpose, but its reproducibility has not been established...
  3. doi request reprint Changes in volume-corrected whole-lung density in smokers and former smokers during the ITALUNG screening trial
    Mario Mascalchi
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Viale Morgagni 85, Florence, Italy
    J Thorac Imaging 27:255-62. 2012
    ....
  4. pmc Dose exposure in the ITALUNG trial of lung cancer screening with low-dose CT
    M Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Br J Radiol 85:1134-9. 2012
    ....
  5. doi request reprint Magnetic resonance and nuclear medicine imaging in ataxias
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Italy
    Handb Clin Neurol 103:85-110. 2012
    ....
  6. ncbi request reprint Risk-benefit analysis of X-ray exposure associated with lung cancer screening in the Italung-CT trial
    Mario Mascalchi
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Viale Morgagni 85, 50134 Firenze, Italia
    AJR Am J Roentgenol 187:421-9. 2006
    ....
  7. doi request reprint Spinocerebellar ataxias
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, 50134 Florence, Italy
    Neurol Sci 29:311-3. 2008
    ..Non conventional MRI techniques detect nervous tissue abnormalities before development of atrophy which are correlated with the severity of the clinical deficit...
  8. ncbi request reprint Huntington disease: volumetric, diffusion-weighted, and magnetization transfer MR imaging of brain
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology and Department of Neurological Sciences, University of Florence, Viale Morgagni 85, Florence, Italy
    Radiology 232:867-73. 2004
    ..To investigate whether diffusion-weighted and magnetization transfer (MT) magnetic resonance (MR) imaging depict regional and/or global brain abnormalities in patients with Huntington disease (HD)...
  9. ncbi request reprint Diffusion-weighted MR of the brain: methodology and clinical application
    Mario Mascalchi
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Florence, Italy
    Radiol Med 109:155-97. 2005
    ..In all these diseases the diffusion changes are correlated to the clinical deficit and are potentially useful for early diagnosis and longitudinal evaluation, especially in the context of pharmacological trials...
  10. ncbi request reprint Early MR imaging and spectroscopy appearance of eIF2B-related leukoencephalopathy
    M Mascalchi
    Radidodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Neurology 67:537-8. 2006
  11. ncbi request reprint Single-voxel long TE 1H-MR spectroscopy of the normal brainstem and cerebellum
    Mario Mascalchi
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Firenze, Italy
    J Magn Reson Imaging 16:532-7. 2002
    ....
  12. ncbi request reprint Longitudinal evaluation of leukoaraiosis with whole brain ADC histograms
    M Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, USA
    Neurology 59:938-40. 2002
    ..008) and brain volume index (BVI) was decreased (p = 0.006). WB-ADC histogram and BVI are sensitive to leukoaraiosis and might be considered for monitoring progression of the disease...
  13. ncbi request reprint Expanding lacunae causing triventricular hydrocephalus. Report of two cases
    M Mascalchi
    Dipartimento de Fisiopatologia Clinica, Clinica Neurologica, Universita di Firenze, Florence, Italy
    J Neurosurg 91:669-74. 1999
    ..A review of the literature revealed two cases in which magnetic resonance imaging demonstrated a similar, poorly understood pathological condition...
  14. ncbi request reprint Failure of radiation therapy for brain involvement in Erdheim Chester disease
    Mario Mascalchi
    Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Italia
    J Neurooncol 59:169-72. 2002
    ..In line with the results in four patients reported in the literature, our observation indicates that external radiation therapy is not effective for intracranial involvement in ECD...
  15. ncbi request reprint Whole brain apparent diffusion coefficient histogram: a new tool for evaluation of leukoaraiosis
    Mario Mascalchi
    Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Firenze, Italy
    J Magn Reson Imaging 15:144-8. 2002
    ..To test whole brain apparent diffusion coefficient histogram analysis as an alternative approach to visual score for the assessment of leukoaraiosis (LA). MATERIALS and..
  16. ncbi request reprint Brainstem involvement in Unverricht-Lundborg disease (EPM1): An MRI and (1)H MRS study
    M Mascalchi
    Diagnostic Radiology, Department of Clinical Pathophysiology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Neurology 58:1686-9. 2002
    ..The N-acetylaspartate/creatine and choline/creatine ratios were reduced in the pons but not in the dentate (p < or = 0.005). Brainstem involvement could play a role in pathophysiology of EPM1...
  17. ncbi request reprint Movement disorders: role of imaging in diagnosis
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Magn Reson Imaging 35:spcone. 2012
    ..A combination of the clinical features with MRI and SPECT is recommended for optimization of the diagnostic algorithm in movement disorders. J. Magn. Reson. Imaging 2012 © 2012 Wiley Periodicals, Inc...
  18. doi request reprint Movement disorders: role of imaging in diagnosis
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Magn Reson Imaging 35:239-56. 2012
    ..A combination of the clinical features with MRI and SPECT is recommended for optimization of the diagnostic algorithm in movement disorders...
  19. doi request reprint Impact of cerebrospinal fluid contamination on brain metabolites evaluation with 1H-MR spectroscopy: a single voxel study of the cerebellar vermis in patients with degenerative ataxias
    Laura Guerrini
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Magn Reson Imaging 30:11-7. 2009
    ..To investigate the impact of cerebrospinal fluid (CSF) contamination on metabolite evaluation in the superior cerebellar vermis with single-voxel (1)H-MRS in normal subjects and patients with degenerative ataxias...
  20. ncbi request reprint Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation
    Ilaria Orlandi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence 50134, Italy
    Radiology 234:604-10. 2005
    ....
  21. doi request reprint Prevalence and correlates of pulmonary emphysema in smokers and former smokers. A densitometric study of participants in the ITALUNG trial
    Gianna Camiciottoli
    Dipartimento Area Critica, Universita di Firenze, Firenze, Italy
    Eur Radiol 19:58-66. 2009
    ..24) or MLA (R2 = 0.34) was significantly, but weakly explained by age, lung volume and packs/year. Other factors besides smoking may also have a significant role in the etiopathogenesis of pulmonary emphysema...
  22. pmc Screening for colorectal cancer with FOBT, virtual colonoscopy and optical colonoscopy: study protocol for a randomized controlled trial in the Florence district (SAVE study)
    Lapo Sali
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale G, Pieraccini 6, 50139 Florence, Italy
    Trials 14:74. 2013
    ..We designed a randomized controlled trial to compare participation rate and diagnostic yield of FOBT, CTC with computer-aided diagnosis, and OC as primary tests for population-based screening...
  23. doi request reprint Brain white matter damage in SCA1 and SCA2. An in vivo study using voxel-based morphometry, histogram analysis of mean diffusivity and tract-based spatial statistics
    Riccardo Della Nave
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Viale Morgagni 85, 50134 Florence, Italy
    Neuroimage 43:10-9. 2008
    ..We assessed with these 3 techniques the whole brain WM damage in SCA1 and SCA2...
  24. ncbi request reprint ADC mapping of neurodegeneration in the brainstem and cerebellum of patients with progressive ataxias
    Riccardo Della Nave
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Neuroimage 22:698-705. 2004
    ..Diffusion MR imaging reveals variable patterns of increase of D in the brainstem, cerebellum, and cerebral hemispheres in degenerative ataxias that match the known distribution of the neuropathological changes...
  25. ncbi request reprint Spirometric-gated computed tomography quantitative evaluation of lung emphysema in chronic obstructive pulmonary disease: a comparison of 3 techniques
    Ilaria Orlandi
    Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Comput Assist Tomogr 28:437-42. 2004
    ....
  26. ncbi request reprint Lung CT densitometry in systemic sclerosis: correlation with lung function, exercise testing, and quality of life
    Gianna Camiciottoli
    Respiratory Medicine Unit, Department of Critical Care, Universita degli Studi di Firenze, Viale Morgagni 85, Firenze, Italy
    Chest 131:672-81. 2007
    ....
  27. doi request reprint Four-year results of low-dose CT screening and nodule management in the ITALUNG trial
    Andrea Lopes Pegna
    Pneumonology Department, Careggi Hospital, Florence, Italy
    J Thorac Oncol 8:866-75. 2013
    ..We report subjects' compliance and results of LDCT screening and management protocol in the active arm of the ITALUNG trial...
  28. ncbi request reprint Thin-section and low-dose volumetric computed tomographic densitometry of the lung in systemic sclerosis
    Ilaria Orlandi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Italy
    J Comput Assist Tomogr 30:823-7. 2006
    ..To correlate lung density measurements with the results of visual assessment of thin-section computed tomography (CT) and of pulmonary function tests (PFT) in Systemic Sclerosis (SSc)...
  29. doi request reprint Neurodegeneration in friedreich's ataxia is associated with a mixed activation pattern of the brain. A fMRI study
    Andrea Ginestroni
    Department of Clinical Physiopathology, Radiodiagnostic Section, University of Florence, Florence, Italy
    Hum Brain Mapp 33:1780-91. 2012
    ....
  30. doi request reprint Brain structural damage in spinocerebellar ataxia type 1 : a VBM study
    Andrea Ginestroni
    Radiodiagnostic Section, Dept of Clinical Physiopathology, University of Florence, Viale Morgagni 85, 50134, Florence, Italy
    J Neurol 255:1153-8. 2008
    ..We assessed with VBM the structural damage in patients with genetically confirmed SCA1...
  31. ncbi request reprint Subcortical damage and cortical functional changes in men and women with Fabry disease: a multifaceted MR study
    Cinzia Gavazzi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence, Italy
    Radiology 241:492-500. 2006
    ..To prospectively compare brain magnetic resonance (MR) imaging and hydrogen 1 (1H) MR spectroscopy findings and to use functional MR imaging to explore the patterns of brain activation in men and women with Fabry disease (FD)...
  32. doi request reprint Design, recruitment and baseline results of the ITALUNG trial for lung cancer screening with low-dose CT
    Andrea Lopes Pegna
    Pneumology Department, Careggi Hospital, Florence, Italy
    Lung Cancer 64:34-40. 2009
    ..We report design and results of enrolment and baseline screening test in the ITALUNG trial, a RCT...
  33. doi request reprint Whole-lung densitometry versus visual assessment of emphysema
    Edoardo Cavigli
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence, 50134, Italy
    Eur Radiol 19:1686-92. 2009
    ..62). Densitometry should be preferred to visual assessment because it enables a more reproducible evaluation of the extent of pulmonary emphysema, which can be carried out on the entire lung in a reasonable amount of time...
  34. ncbi request reprint Combining functional and structural brain magnetic resonance imaging in Huntington disease
    Cinzia Gavazzi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Comput Assist Tomogr 31:574-80. 2007
    ..To concurrently investigate with magnetic resonance (MR) the brain activation and regional brain atrophy in patients with Huntington disease (HD)...
  35. ncbi request reprint Proton MR spectroscopy of the cerebellum and pons in patients with degenerative ataxia
    Mario Mascalchi
    Section of Diagnostic Radiology, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Radiology 223:371-8. 2002
    ..To investigate whether proton magnetic resonance (MR) spectroscopy is a useful complement to MR imaging in patients with degenerative ataxia...
  36. doi request reprint The burden of microstructural damage modulates cortical activation in elderly subjects with MCI and leuko-araiosis. A DTI and fMRI study
    Mario Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Hum Brain Mapp 35:819-30. 2014
    ..Hum Brain Mapp 35:819-830, 2014. © Wiley Periodicals, Inc. ..
  37. doi request reprint The LoG characteristic scale: a consistent measurement of lung nodule size in CT imaging
    Stefano Diciotti
    Department of Electronics and Telecommunications, University of Florence, 50134 Florence, Italy
    IEEE Trans Med Imaging 29:397-409. 2010
    ..9 mm was observed. Experimental evidence supports the clinical use of the LoG characteristic scale to measure nodule size in CT imaging...
  38. ncbi request reprint Operator-dependent reproducibility of size measurements of small phantoms and lung nodules examined with low-dose thin-section computed tomography
    Giulia Picozzi
    Radiodiagnostic, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Invest Radiol 41:831-9. 2006
    ..We sought to assess the reproducibility of size measurements of small lung nodules examined with low-dose thin-section computed tomography (LDTSCT)...
  39. doi request reprint Brain white matter tracts degeneration in Friedreich ataxia. An in vivo MRI study using tract-based spatial statistics and voxel-based morphometry
    Riccardo Della Nave
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence, Italy
    Neuroimage 40:19-25. 2008
    ..Tract-based spatial statistics (TBSS) enables an unbiased whole-brain quantitative analysis of the fractional anisotropy (FA) and mean diffusivity (MD) of the brain WM tracts in vivo...
  40. doi request reprint Defining the intra-subject variability of whole-lung CT densitometry in two lung cancer screening trials
    Stefano Diciotti
    Computational Biomedical Imaging Laboratory, Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Acad Radiol 18:1403-11. 2011
    ..To define a statistically based variation of individual whole-lung densitometry above which a real increase of pulmonary extent can be suspected in lung cancer screening trials...
  41. doi request reprint BODE-index, modified BODE-index and ADO-score in chronic obstructive pulmonary disease: relationship with COPD phenotypes and CT lung density changes
    Gianna Camiciottoli
    University of Florence, Department of Internal Medicine, Section of Respiratory Medicine, Florence, Italy it
    COPD 9:297-304. 2012
    ..BODE reflect COPD severity better than other MGS, but not its clinical heterogeneity. 6MWT does not significantly increase BODE predictivity of CT lung density changes...
  42. doi request reprint Brain structural damage in spinocerebellar ataxia type 2. A voxel-based morphometry study
    Riccardo Della Nave
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Mov Disord 23:899-903. 2008
    ..In SCA2 patients with mild to moderate cerebellar deficit, GM and WM volume loss and CSF volume increase are confined to the posterior cranial fossa...
  43. ncbi request reprint Spirometrically gated high-resolution CT findings in COPD: lung attenuation vs lung function and dyspnea severity
    Gianna Camiciottoli
    Department of Critical Care, Section of Respiratory Medicine, University of Florence, Florence, Italy
    Chest 129:558-64. 2006
    ....
  44. ncbi request reprint Proton MR spectroscopy of cerebellitis
    Laura Guerrini
    Radiodiagnostica I, Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Viale Morgagni 85, Italy
    Magn Reson Imaging 20:619-22. 2002
    ..The NAA/Cr and NAA/Cho ratios and NAA concentration were increased in (1)H-MRS examinations obtained 10 and 24 months after the acute episode. (1)H-MRS demonstrates reversible metabolite changes in cerebellitis...
  45. doi request reprint Axial diffusivity is increased in the degenerating superior cerebellar peduncles of Friedreich's ataxia
    Riccardo Della Nave
    S Giuseppe Hospital, Radiodiagnostic Section, Empoli, Italy
    Neuroradiology 53:367-72. 2011
    ....
  46. doi request reprint Computed tomographic colonography in subjects with positive faecal occult blood test refusing optical colonoscopy
    Lapo Sali
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale G Pieraccini 6, 50139 Florence, Italy
    Dig Liver Dis 45:285-9. 2013
    ..Refusal of colonoscopy is a drawback of colorectal cancer screening programmes based on faecal occult blood test. Computed-tomographic-colonography is generally more accepted than colonoscopy...
  47. ncbi request reprint Proton MR spectroscopy of Wernicke encephalopathy
    Mario Mascalchi
    Department of Clinical Pathophysiology, Radiodiagnostica I, Universita di Firenze, Firenze, Italy
    AJNR Am J Neuroradiol 23:1803-6. 2002
    ..Owing to substantially decreased choline (Cho) T2, the Cho/Cr ratio was not decreased. After thiamine therapy, the NAA/Cr ratio increased, paralleling clinical improvement and reduction in the areas of signal-intensity changes...
  48. doi request reprint Automated segmentation refinement of small lung nodules in CT scans by local shape analysis
    Stefano Diciotti
    Department of Clinical Physiopathology, University of Florence, Italy
    IEEE Trans Biomed Eng 58:3418-28. 2011
    ..The proposed correction method could also be usefully applied to any existent nodule segmentation algorithm for improving the segmentation quality of juxta-vascular nodules...
  49. ncbi request reprint Self-paced frequency of a simple motor task and brain activation. An fMRI study in healthy subjects using an on-line monitor device
    Stefano Diciotti
    Department of Electronics and Telecommunications, University of Florence, Via S Marta 3, 50139, Florence, Italy
    Neuroimage 38:402-12. 2007
    ..2-2 Hz range are not a relevant source of the variability of the fMRI results in healthy subjects. Use of the device for evaluation of the neurologically impaired patients might broaden the clinical applications of fMRI...
  50. doi request reprint Scenes from the past: the Medici Project: radiographic survey
    Natale Villari
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    Radiographics 29:2101-14. 2009
    ....
  51. doi request reprint Human striatal neuroblasts develop and build a striatal-like structure into the brain of Huntington's disease patients after transplantation
    Pasquale Gallina
    Department of Neurosurgery, University of Florence, Florence, Italy
    Exp Neurol 222:30-41. 2010
    ..Further studies are necessary to assess the clinical efficacy of the human fetal striatal transplantation...
  52. doi request reprint Computation of brain metabolite ratios in single-voxel proton MR spectroscopy: comparison between semiautomatic and automatic software
    L N Mazzoni
    CIRM University of Florence, Florence, Italy
    Radiol Med 115:125-32. 2010
    ..We evaluated the agreement between the metabolite ratios calculated with semiautomatic and automatic software...
  53. doi request reprint Molecular profile in body fluids in subjects enrolled in a randomised trial for lung cancer screening: Perspectives of integrated strategies for early diagnosis
    Francesca Maria Carozzi
    Analytical and Biomolecular Cytology Unit, ISPO Cancer Prevention and Research Institute, Via Cosimo il Vecchio 2, 50139 Florence, Italy
    Lung Cancer 68:216-21. 2010
    ..This study, embedded in an early diagnosis randomised trial, suggests that a multi-screening approach integrating imaging technique and a biomolecular marker panel is worth of further investigation...
  54. doi request reprint Identification of mild Alzheimer's disease through automated classification of structural MRI features
    Stefano Diciotti
    Computational Biomedical Imaging Laboratory, Department of Clinical Pathophysiology, University of Florence, Florence, Italy
    Conf Proc IEEE Eng Med Biol Soc 2012:428-31. 2012
    ....
  55. ncbi request reprint Comparison of spirometric-gated and -ungated HRCT in COPD
    Chiara Moroni
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Pisa, Italy
    J Comput Assist Tomogr 27:375-9. 2003
    ....
  56. pmc Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort
    Domenico Inzitari
    Department of Neurological and Psychiatric Sciences, University of Florence, Viale Morgagni 85, 50134 Firenze, Italy
    BMJ 339:b2477. 2009
    ..To assess the impairment in daily living activities in older people with age related changes in white matter according to the severity of these changes...
  57. ncbi request reprint SDH mutations in patients affected by paraganglioma syndromes: a personal experience
    M Mannelli
    Endocrinology Section, Department of Clinical Physiopathology, University of Florence, Viale Pieraccini 6 50139, Florence, and Internal Medicine 2, Pistoia Hospital, Italy
    Ann N Y Acad Sci 1073:183-9. 2006
    ..All the tumors associated with SDHD mutations were benign. Conversely, the only mutation we found in SDHB gene (IVS3+1G>A) was associated with a malignant PHEO...
  58. ncbi request reprint Alzheimer's disease: role of size and location of white matter changes in determining cognitive deficits
    L Bracco
    Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy
    Dement Geriatr Cogn Disord 20:358-66. 2005
    ..Our results underline the significance of WMC location over size in the occurrence of specific cognitive deficits in AD...
  59. ncbi request reprint Phase-contrast MR angiography of intracranial dural arteriovenous fistulae
    M Cellerini
    Department of Clinical Physiopathology, University of Florence, Italy
    Neuroradiology 41:487-92. 1999
    ..In six patients with type II DAVF phase reconstruction of 2D PC MRA demonstrated flow reversal in the dural sinuses or superior ophthalmic vein...
  60. doi request reprint CT colonography before colonoscopy in subjects with positive faecal occult blood test. Preliminary experience
    L Sali
    Radiodiagnostic Section Department of Clinical Physiopathology, University of Florence, Viale G B Morgagni 85, Florence, Italy
    Radiol Med 115:1267-78. 2010
    ....
  61. ncbi request reprint Morphometry and 1H-MR spectroscopy of the brain stem and cerebellum in three patients with fragile X-associated tremor/ataxia syndrome
    A Ginestroni
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    AJNR Am J Neuroradiol 28:486-8. 2007
    ..The only spectroscopic abnormality was a decrease of the pontine N-acetylaspartate/creatine ratio in 1 patient. Atrophy and metabolic changes in FXTAS differ to some extent from those of olivopontocerebellar atrophy...
  62. ncbi request reprint Misleading imaging features of intracranial dural plasmacytoma: report of two cases
    P Gallina
    Department of Neurosurgery, University of Florence, Italy
    Br J Neurosurg 18:643-6. 2004
    ..We report two cases. Both patients exhibited headache as a main symptom. Computed tomography and magnetic resonance showed a homogeneously enhanced lesion without calcification and without bone involvement...
  63. doi request reprint 3-D segmentation algorithm of small lung nodules in spiral CT images
    S Diciotti
    Department of Electronics and Telecommunications, University of Florence, 50100 Florence, Italy
    IEEE Trans Inf Technol Biomed 12:7-19. 2008
    ..The achieved results support the use of the proposed algorithm for volume measurements of lung nodules examined with low-dose CT scanning technique...
  64. ncbi request reprint A direct ROI quantification method for inherent PVE correction: accuracy assessment in striatal SPECT measurements
    Eleonora Vanzi
    Clinical Pathophysiology, University of Florence, Viale Morgagni, 85, Florence, 50134, Italy
    Eur J Nucl Med Mol Imaging 34:1480-9. 2007
    ..We evaluated the accuracy of a least squares method that allows retrieval of activity in regions of interest directly from projections (LS-ROI)...
  65. doi request reprint Osteochondritis dissecans of the patella in a XVII century player of the Florentine historic kickball
    Donatella Lippi
    History of Medicine, Department of Anatomy, Histology and Legal Medicine, University of Florence, Italy
    Knee 17:172-3. 2010
    ..He was known to play Florentine kick ball, a precursor of Rugby and American football, and speculate that trauma from this activity may have led to the lesion...
  66. pmc CT colonography after incomplete colonoscopy in subjects with positive faecal occult blood test
    Lapo Sali
    Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence 50134, Italy
    World J Gastroenterol 14:4499-504. 2008
    ....
  67. pmc MRI features of pleural endometriosis after catamenial haemothorax
    Giulia Picozzi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 50134, Florence, Italy
    Thorax 62:744. 2007
  68. ncbi request reprint Fragile X premutation with atypical symptoms at onset
    Elena Cellini
    Department of Neurological and Psychiatric Sciences, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy
    Arch Neurol 63:1135-8. 2006
    ..To evaluate the presence of carriers of the fragile X premutation among male patients with sporadic ataxia without expansion into known spinocerebellar ataxia genes...
  69. ncbi request reprint Spinal vascular malformations: MR angiography after treatment
    M Mascalchi
    Department of Clinical Pathophysiology, Section of Radiodiagnostics, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Radiology 219:346-53. 2001
    ..CONCLUSION: MR angiography is more sensitive than MR imaging in depicting residual or recurrent flow in peri- or intramedullary vessels, which indicates patency of the vascular malformation...
  70. doi request reprint Early structural changes in individuals at risk of familial Alzheimer's disease: a volumetry and magnetization transfer MR imaging study
    A Ginestroni
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence, Italy
    J Neurol 256:925-32. 2009
    ..Early neurodegeneration in non-demented subjects at risk for familial AD may be associated with atrophy and decreased MTR in the temporal cortex...
  71. pmc Risk and Determinants of Dementia in Patients with Mild Cognitive Impairment and Brain Subcortical Vascular Changes: A Study of Clinical, Neuroimaging, and Biological Markers-The VMCI-Tuscany Study: Rationale, Design, and Methodology
    Anna Poggesi
    Department of Neurological and Psychiatric Sciences, University of Florence, Largo Brambilla 3, 50134 Florence, Italy
    Int J Alzheimers Dis 2012:608013. 2012
    ..This paper summarizes the main aims and methodological aspects of this multicenter, ongoing, observational study enrolling patients affected by VMCI with SVD...
  72. doi request reprint Predicting the status of axillary lymph nodes in breast cancer: a multiparameter approach including axillary ultrasound scanning
    Tommaso Susini
    Department of Gynecology, Breast Unit, University of Florence, Italy
    Breast 18:103-8. 2009
    ..The accuracy of this predictive model still requires prospective validation in a larger sample of women...
  73. pmc Phenotype variability of neural crest derived tumours in six Italian families segregating the same founder SDHD mutation Q109X
    L Simi
    Section of Endocrinology, Department of Clinical Physiopathology, University of Florence Medical School, Florence, Italy
    J Med Genet 42:e52. 2005
    ..Mutations in genes coding for the mitochondrial complex II succinate dehydrogenase (SDH) subunits cause familial neural crest derived (NCD) tumours...
  74. ncbi request reprint CT and MR imaging of neuroaxonal leukodystrophy presenting as early-onset frontal dementia
    M Mascalchi
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Italy
    AJNR Am J Neuroradiol 27:1037-9. 2006
    ..This disease can be suspected on CT and MR imaging findings but requires neuropathologic examination to be diagnosed...
  75. doi request reprint Urinary complaints in nondisabled elderly people with age-related white matter changes: the Leukoaraiosis And DISability (LADIS) Study
    Anna Poggesi
    Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy
    J Am Geriatr Soc 56:1638-43. 2008
    ..To investigate, in a cohort of nondisabled elderly people, the association between urinary complaints and severity of age-related white matter changes (ARWMC)...
  76. ncbi request reprint Screening of lung cancer with low dose spiral CT: results of a three year pilot study and design of the randomised controlled trial ''Italung-CT''
    G Picozzi
    Radiodiagnostica I, Dipartimento di Fisiopatologia Clinica, Universita degli Studi di Firenze, Italy
    Radiol Med 109:17-26. 2005
    ..To report the results of a three-year observational pilot study of lung cancer screening with low dose computed tomography (CT) and to present the study design of a randomised clinical trial named as ''Italung-CT''...
  77. ncbi request reprint Whole-brain histogram and voxel-based analyses of diffusion tensor imaging in patients with leukoaraiosis: correlation with motor and cognitive impairment
    R Della Nave
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, and Medical Physics, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    AJNR Am J Neuroradiol 28:1313-9. 2007
    ....
  78. ncbi request reprint [High resolution and spirometric synchronization computerized tomography in chronic obstructive bronchopneumopathy]
    C Moroni
    Sezione di Radiodiagnostica, Dipartimento di Fisiopatologia Clinica, , Firenze
    Radiol Med 101:25-30. 2001
    ..Spirometrically gated HRCT densitometry is a promising tool for longitudinal studies of diffuse lung disease (pulmonary emphysema and fibrosis)...
  79. ncbi request reprint Whole-brain histogram and voxel-based analyses of apparent diffusion coefficient and magnetization transfer ratio in celiac disease, epilepsy, and cerebral calcifications syndrome
    R Della Nave
    Section of Radiodiagnostics, University of Florence, Florence, Italy
    AJNR Am J Neuroradiol 28:479-85. 2007
    ..We hypothesized that also in the coeliac disease (CD), epilepsy and cerebral calcifications (CEC) syndrome diffusion and MT techniques could reveal brain abnormalities undetected by MR imaging and tentatively correlated to epilepsy...
  80. ncbi request reprint Solitary necrotic nodule of the liver: imaging and correlation with pathologic features
    S Colagrande
    Radiodiagnostic Unit, Clinical Physiopathology Department, University of Florence, Careggi Hospital, Viale Morgagni 85, 50134 Firenze, Italy
    Abdom Imaging 28:41-4. 2003
    ..These features, peculiar when considered together, are explained by the coagulative type of necrosis...
  81. doi request reprint Neurological picture. An unusual cause of cord compression: synovial cyst of the thoracic spine
    A Pratesi
    Department of Clinical Physiopathology, Radiodiagnostic Section, University of Florence, Florence, Italy
    J Neurol Neurosurg Psychiatry 79:947. 2008
  82. ncbi request reprint Brain structural damage in Friedreich's ataxia
    R Della Nave
    Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Florence, Viale Morgagni 85, 50134 Florence, Italy
    J Neurol Neurosurg Psychiatry 79:82-5. 2008
    ..Voxel-based morphometry (VBM) enables an unbiased whole-brain quantitative analysis of differences in gray matter (GM) and white matter (WM) volume...
  83. ncbi request reprint MRI and SPECT of midbrain and striatal degeneration in fragile X-associated tremor/ataxia syndrome
    Cesa Scaglione
    J Neurol 255:144-6. 2008
  84. ncbi request reprint A functional magnetic resonance imaging study of patients with secondary progressive multiple sclerosis
    Maria A Rocca
    Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Neuroimage 19:1770-7. 2003
    ..It also suggests that, in these patients, functional abilities are sustained by increased recruitment of highly specialized cortical areas...
  85. doi request reprint On the etiology of incident brain lacunes: longitudinal observations from the LADIS study
    Alida A Gouw
    Alzheimer Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Stroke 39:3083-5. 2008
    ..We investigated regional differences in MRI characteristics and risk factor profiles of incident lacunes over a 3-year period...
  86. ncbi request reprint Adult Alexander's disease without leukoencephalopathy
    Fabrizio Salvi
    Ann Neurol 58:813-4. 2005
  87. ncbi request reprint Primary diffuse meningeal melanomatosis: radiologic-pathologic correlation
    Maria Giulia Pirini
    Pathology Unit of the Addarii Institute of Oncology, Policlinico S Orsola Malpighi, The University of Bologna, Italy
    AJNR Am J Neuroradiol 24:115-8. 2003
    ..The clinical, radiologic, and pathologic features of diffuse meningeal melanomatosis are reviewed...
  88. doi request reprint Reliability and sensitivity of visual scales versus volumetry for evaluating white matter hyperintensity progression
    A A Gouw
    Alzheimer Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Cerebrovasc Dis 25:247-53. 2008
    ..However, the most suitable method for measuring WMH progression has not been established yet. We compared the reliability and sensitivity of cross-sectional and longitudinal visual scales with volumetry for measuring WMH progression...
  89. ncbi request reprint Magnetization transfer and diffusion tensor MR imaging of acute disseminated encephalomyelitis
    Matilde Inglese
    Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    AJNR Am J Neuroradiol 23:267-72. 2002
    ..We used magnetization transfer and diffusion tensor MR imaging to quantify normal-appearing brain tissue and cervical cord disease in patients with ADEM and to compare findings with those in healthy volunteers and patients with MS...