Alessandro Martino

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. doi Application of high-resolution melting to large-scale, high-throughput SNP genotyping: a comparison with the TaqMan method
    Alessandro Martino
    Department of Biology Section Genetics, University of Pisa, Pisa, Italy
    J Biomol Screen 15:623-9. 2010
  2. doi MDR1 diplotypes as prognostic markers in multiple myeloma
    Valentina Maggini
    Department of Biology, Transplants and Advanced Technologies, Section of Hematology, Pisa University, Pisa, Italy
    Pharmacogenet Genomics 18:383-9. 2008
  3. ncbi Lack of association of NQO1 and GSTP1 polymorphisms with multiple myeloma risk
    Valentina Maggini
    Department of Biology, Pisa University, Pisa, Italy
    Leuk Res 32:988-90. 2008
  4. doi Could age modify the effect of genetic variants in IL6 and TNF-α genes in multiple myeloma?
    Alessandro Martino
    Department of Biology, Genetics Division, University of Pisa, Italy
    Leuk Res 36:594-7. 2012
  5. pmc Pacing-induced regional differences in adenosine receptors mRNA expression in a swine model of dilated cardiomyopathy
    Silvia Del Ry
    Institute of Clinical Physiology, CNR, Pisa, Italy
    PLoS ONE 7:e47011. 2012
  6. pmc Selection of reference genes in different myocardial regions of an in vivo ischemia/reperfusion rat model for normalization of antioxidant gene expression
    Nicoletta Vesentini
    Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa, Italy
    BMC Res Notes 5:124. 2012
  7. doi Selection of reference genes for normalization of real-time PCR data in minipig heart failure model and evaluation of TNF-α mRNA expression
    Alessandro Martino
    University of Pisa, Department of Biology, Genetics Division, Italy
    J Biotechnol 153:92-9. 2011
  8. doi Adenosine receptor mRNA expression in normal and failing minipig hearts
    Silvia Del Ry
    Laboratory of Cardiovascular Biochemistry, CNR Institute of Clinical Physiology, Pisa, Italy
    J Cardiovasc Pharmacol 58:149-56. 2011
  9. ncbi MDR1 polymorphism influences the outcome of multiple myeloma patients
    Gabriele Buda
    Department of Oncology, Transplants and Advanced Technologies, Section of Hematology, Pisa University, Pisa, Italy
    Br J Haematol 137:454-6. 2007

Detail Information

Publications9

  1. doi Application of high-resolution melting to large-scale, high-throughput SNP genotyping: a comparison with the TaqMan method
    Alessandro Martino
    Department of Biology Section Genetics, University of Pisa, Pisa, Italy
    J Biomol Screen 15:623-9. 2010
    ....
  2. doi MDR1 diplotypes as prognostic markers in multiple myeloma
    Valentina Maggini
    Department of Biology, Transplants and Advanced Technologies, Section of Hematology, Pisa University, Pisa, Italy
    Pharmacogenet Genomics 18:383-9. 2008
    ..The aim of this study was to evaluate the effect of diplotypes of MDR1 polymorphisms at positions 2677 and 3435 on the clinical outcome of multiple myeloma, in terms of response to the therapy and overall survival (OS)...
  3. ncbi Lack of association of NQO1 and GSTP1 polymorphisms with multiple myeloma risk
    Valentina Maggini
    Department of Biology, Pisa University, Pisa, Italy
    Leuk Res 32:988-90. 2008
    ..Individual genotypes of 128 patients affected by multiple myeloma and 245 healthy controls were determined and our results do not support any major role of NQO1 or GSTP1 polymorphisms in multiple myeloma pathogenesis...
  4. doi Could age modify the effect of genetic variants in IL6 and TNF-α genes in multiple myeloma?
    Alessandro Martino
    Department of Biology, Genetics Division, University of Pisa, Italy
    Leuk Res 36:594-7. 2012
    ..Therefore, this observation suggests that genetic variation in inflammation-related genes could be an important mediator of the complex interplay between ageing and cancer...
  5. pmc Pacing-induced regional differences in adenosine receptors mRNA expression in a swine model of dilated cardiomyopathy
    Silvia Del Ry
    Institute of Clinical Physiology, CNR, Pisa, Italy
    PLoS ONE 7:e47011. 2012
    ..These results suggest a possible therapeutic role of adenosine in patients with HF and dyssynchronous LV contraction...
  6. pmc Selection of reference genes in different myocardial regions of an in vivo ischemia/reperfusion rat model for normalization of antioxidant gene expression
    Nicoletta Vesentini
    Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa, Italy
    BMC Res Notes 5:124. 2012
    ..Changes in cardiac gene expression due to myocardial injury are usually assessed in whole heart tissue. However, as the heart is a heterogeneous system, spatial and temporal heterogeneity is expected in gene expression...
  7. doi Selection of reference genes for normalization of real-time PCR data in minipig heart failure model and evaluation of TNF-α mRNA expression
    Alessandro Martino
    University of Pisa, Department of Biology, Genetics Division, Italy
    J Biotechnol 153:92-9. 2011
    ..The use of unvalidated reference genes can generate biased results because also their expression could be altered by the experimental conditions...
  8. doi Adenosine receptor mRNA expression in normal and failing minipig hearts
    Silvia Del Ry
    Laboratory of Cardiovascular Biochemistry, CNR Institute of Clinical Physiology, Pisa, Italy
    J Cardiovasc Pharmacol 58:149-56. 2011
    ..80, P < 0.0001). In this study, A2BR mRNA resulted in being overexpressed in the left ventricle of pigs with HF as well as TNF-α expression possibly testifying a link between AR expression, inflammation, and HF...
  9. ncbi MDR1 polymorphism influences the outcome of multiple myeloma patients
    Gabriele Buda
    Department of Oncology, Transplants and Advanced Technologies, Section of Hematology, Pisa University, Pisa, Italy
    Br J Haematol 137:454-6. 2007
    ..Our data suggested a longer OS for patients with C/T and T/T genotypes (log-rank test, P = 0.02) compared with patients with C/C genotype...