Guido Martignoni

Summary

Affiliation: University of Verona
Country: Italy

Publications

  1. doi request reprint Cathepsin-K immunoreactivity distinguishes MiTF/TFE family renal translocation carcinomas from other renal carcinomas
    G Martignoni
    Anatomia Patologica, Universita di Verona, Verona, Italy
    Mod Pathol 22:1016-22. 2009
  2. doi request reprint Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions
    Guido Martignoni
    Department of Pathology and Diagnostic, University of Verona, Verona, Italy
    Mod Pathol 24:1313-9. 2011
  3. doi request reprint Genotypic intratumoral heterogeneity in breast carcinoma with HER2/neu amplification: evaluation according to ASCO/CAP criteria
    Matteo Brunelli
    Anatomic Pathology, Department of Pathology, University of Verona, Verona, Italy
    Am J Clin Pathol 131:678-82. 2009
  4. doi request reprint Diagnostic usefulness of fluorescent cytogenetics in differentiating chromophobe renal cell carcinoma from renal oncocytoma: a validation study combining metaphase and interphase analyses
    Matteo Brunelli
    1Department of Pathology, University of Verona, Verona, Italy
    Am J Clin Pathol 133:116-26. 2010
  5. ncbi request reprint Loss of chromosome 9p is an independent prognostic factor in patients with clear cell renal cell carcinoma
    Matteo Brunelli
    Department of Pathology, University of Verona, Verona, Italy
    Mod Pathol 21:1-6. 2008
  6. ncbi request reprint Utility of tissue microarrays for assessment of chromosomal abnormalities in chromophobe renal cell carcinoma
    Matteo Brunelli
    Department of Pathology, University of Verona, Verona, Italy
    Anal Quant Cytol Histol 31:401-9. 2009
  7. ncbi request reprint HER2/neu gene determination in women screened for breast carcinoma: how screening programs reduce the skyrocketing cost of targeted therapy
    Matteo Brunelli
    Department of Pathology and Diagnostics, University of Verona, p le L Scuro n 10, 37134 Verona, Italy
    Anticancer Res 33:3705-10. 2013
  8. doi request reprint Utility of racemase and other immunomarkers in the detection of adenocarcinoma in prostatic tissue damaged by high intensity focused ultrasound therapy
    Daniela Dalfior
    Department of Pathology, Universita di Verona, Italy
    Pathology 42:1-5. 2010
  9. ncbi request reprint FISH scoring on paraffin sections versus single-cell suspension for chromophobe renal carcinoma and renal oncocytoma
    Matteo Brunelli
    Department of Pathology and Diagnostic, University of Verona, P le Ludovico Scuro 10, 37134 Verona, Italy
    Anticancer Res 31:3137-42. 2011
  10. doi request reprint Her-2/neu evaluation in Sister Mary Joseph's nodule from breast carcinoma: a case report and review of the literature
    Matteo Brunelli
    Department of Pathology, University of Verona, Verona, Italy
    J Cutan Pathol 36:702-5. 2009

Collaborators

Detail Information

Publications50

  1. doi request reprint Cathepsin-K immunoreactivity distinguishes MiTF/TFE family renal translocation carcinomas from other renal carcinomas
    G Martignoni
    Anatomia Patologica, Universita di Verona, Verona, Italy
    Mod Pathol 22:1016-22. 2009
    ..3) These results further support the concept that the overexpression of TFE3 or TFEB in these neoplasms activates the expression of genes normally regulated by microphthalmia transcription factor in other cell types...
  2. doi request reprint Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions
    Guido Martignoni
    Department of Pathology and Diagnostic, University of Verona, Verona, Italy
    Mod Pathol 24:1313-9. 2011
    ....
  3. doi request reprint Genotypic intratumoral heterogeneity in breast carcinoma with HER2/neu amplification: evaluation according to ASCO/CAP criteria
    Matteo Brunelli
    Anatomic Pathology, Department of Pathology, University of Verona, Verona, Italy
    Am J Clin Pathol 131:678-82. 2009
    ..The clinical relevance and impact on treatment outcome of intratumoral heterogeneity in breast cancer with low-grade HER2/neu amplification or chromosome 17 polysomy need further investigation...
  4. doi request reprint Diagnostic usefulness of fluorescent cytogenetics in differentiating chromophobe renal cell carcinoma from renal oncocytoma: a validation study combining metaphase and interphase analyses
    Matteo Brunelli
    1Department of Pathology, University of Verona, Verona, Italy
    Am J Clin Pathol 133:116-26. 2010
    ..The study demonstrates that indeed FISH performed on formalin-fixed, paraffin-embedded tissue can provide clinically useful information more reliably than karyotyping of most of these tumors...
  5. ncbi request reprint Loss of chromosome 9p is an independent prognostic factor in patients with clear cell renal cell carcinoma
    Matteo Brunelli
    Department of Pathology, University of Verona, Verona, Italy
    Mod Pathol 21:1-6. 2008
    ....
  6. ncbi request reprint Utility of tissue microarrays for assessment of chromosomal abnormalities in chromophobe renal cell carcinoma
    Matteo Brunelli
    Department of Pathology, University of Verona, Verona, Italy
    Anal Quant Cytol Histol 31:401-9. 2009
    ..To compare the results of numerical chromosomal changes in chromophobe renal cell carcinoma obtained from whole tissue sections with those of tissue microarrays...
  7. ncbi request reprint HER2/neu gene determination in women screened for breast carcinoma: how screening programs reduce the skyrocketing cost of targeted therapy
    Matteo Brunelli
    Department of Pathology and Diagnostics, University of Verona, p le L Scuro n 10, 37134 Verona, Italy
    Anticancer Res 33:3705-10. 2013
    ..Breast cancer detection by screening programs hijacks the skyrocketing cost of the use of targeted therapy in HER2-positive carcinoma. ..
  8. doi request reprint Utility of racemase and other immunomarkers in the detection of adenocarcinoma in prostatic tissue damaged by high intensity focused ultrasound therapy
    Daniela Dalfior
    Department of Pathology, Universita di Verona, Italy
    Pathology 42:1-5. 2010
    ....
  9. ncbi request reprint FISH scoring on paraffin sections versus single-cell suspension for chromophobe renal carcinoma and renal oncocytoma
    Matteo Brunelli
    Department of Pathology and Diagnostic, University of Verona, P le Ludovico Scuro 10, 37134 Verona, Italy
    Anticancer Res 31:3137-42. 2011
    ....
  10. doi request reprint Her-2/neu evaluation in Sister Mary Joseph's nodule from breast carcinoma: a case report and review of the literature
    Matteo Brunelli
    Department of Pathology, University of Verona, Verona, Italy
    J Cutan Pathol 36:702-5. 2009
    ....
  11. doi request reprint Cathepsin-k expression in pulmonary lymphangioleiomyomatosis
    Marco Chilosi
    Department of Pathology, University of Verona, Verona, Italy
    Mod Pathol 22:161-6. 2009
    ..It is possible to speculate that mTOR inhibitors may exert part of their action by limiting the destructive remodelling of lung structure...
  12. doi request reprint The identification of a small but significant subset of patients still targetable with anti-HER2 inhibitors when affected by triple negative breast carcinoma
    Eleonora Brunello
    Department of Pathology and Diagnostic, University of Verona, P le Scuro n 10, 37134, Verona, Italy
    J Cancer Res Clin Oncol 139:1563-8. 2013
    ..We sought to recruit from a group of triple negative breast carcinoma, patients eligible for effective personalized targeted therapy with anti-HER therapies on the basis of their HER2 gene status...
  13. ncbi request reprint Chromosomal gains in the sarcomatoid transformation of chromophobe renal cell carcinoma
    Matteo Brunelli
    Anatomia Patologica, Dipartimento di Patologia, Universita di Verona, Verona, Italy
    Mod Pathol 20:303-9. 2007
    ....
  14. doi request reprint Cathepsin K expression in the spectrum of perivascular epithelioid cell (PEC) lesions of the kidney
    Guido Martignoni
    Department of Pathology and Diagnostics, University of Verona, Verona, Italy
    Mod Pathol 25:100-11. 2012
    ....
  15. pmc PEComas: the past, the present and the future
    Guido Martignoni
    Department of Pathology, Universita di Verona, Verona, Italy
    Virchows Arch 452:119-32. 2008
    ..Its success could provide the rationale for the use of the same drug in other lesions composed of PECs, especially in the malignant ones...
  16. ncbi request reprint Role of molecular markers in diagnosis and prognosis of renal cell carcinoma
    Guido Martignoni
    Department of Pathology, University of Verona, Verona, Italy
    Anal Quant Cytol Histol 29:41-9. 2007
    ..A wide variety of molecular markers have been examined, but further research is required to prove their value as prognostic tools...
  17. ncbi request reprint External validation of the Mayo Clinic Stage, Size, Grade and Necrosis (SSIGN) score to predict cancer specific survival using a European series of conventional renal cell carcinoma
    Vincenzo Ficarra
    Department of Urology, University of Verona, Verona, Italy
    J Urol 175:1235-9. 2006
    ..We validated the Mayo Clinic SSIGN score in an independent European sample of patients who were surgically treated for conventional RCC...
  18. ncbi request reprint Many facets of chromosome 3p cytogenetic findings in clear cell renal carcinoma: the need for agreement in assessment FISH analysis to avoid diagnostic errors
    Matteo Brunelli
    Department of Pathology and Diagnostic, University of Verona, Italy
    Histol Histopathol 26:1207-13. 2011
    ..This harbours relevant diagnostic and therapeutic implications, at light also of targeted therapies recently available to clear cell renal carcinoma...
  19. ncbi request reprint Prognostic role of the histologic subtypes of renal cell carcinoma after slide revision
    Vincenzo Ficarra
    Department of Urology, University of Verona, Ospedale Policlinico GB Rossi, Italy
    Eur Urol 50:786-93; discussion 793-4. 2006
    ..To evaluate concordance, using the kappa statistic, between tumour histotypes assigned at initial diagnosis and those after slide revision, and to assess the independent predictive value of reviewed tumour histotype...
  20. ncbi request reprint Needle core length is a quality indicator of systematic transperineal prostate biopsy
    Vincenzo Ficarra
    Department of Urology, University of Verona, Italy
    Eur Urol 50:266-71. 2006
    ..To analyse the length of needle cores sampled as a quality indicator in systematic transperineal prostate biopsy. We assessed the correlation of core length with the other clinical and topographic parameters...
  21. pmc FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma
    Eleonora Brunello
    Department of Pathology and Diagnostic, University of Verona, Verona, 37134, Italy
    J Exp Clin Cancer Res 31:103. 2012
    ....
  22. ncbi request reprint Nomogram predictive of pathological inguinal lymph node involvement in patients with squamous cell carcinoma of the penis
    Vincenzo Ficarra
    Department of Urology, University of Verona, Verona, Italy
    J Urol 175:1700-4; discussion 1704-5. 2006
    ..We generated a nomogram estimating the risk of pathological inguinal lymph node involvement according to clinical lymph node stage and pathological findings of the primary tumor...
  23. ncbi request reprint Original and reviewed nuclear grading according to the Fuhrman system: a multivariate analysis of 388 patients with conventional renal cell carcinoma
    Vincenzo Ficarra
    Department of Urology, University of Verona, Verona, Italy
    Cancer 103:68-75. 2005
    ..The objective of the current study was to evaluate the reproducibility of the Fuhrman nuclear grading system as well as its independent predictive value in a series of patients with conventional renal cell carcinoma (RCC)...
  24. ncbi request reprint The potential impact of prostate volume in the planning of optimal number of cores in the systematic transperineal prostate biopsy
    Vincenzo Ficarra
    Department of Urology, University of Verona, Policlinico GB Rossi, Italy
    Eur Urol 48:932-7. 2005
    ..We compared the detection rates of different transperineal prostate biopsy protocols with the aim to optimize the number of cores to sample according to prostate volume...
  25. ncbi request reprint Prognostic factors in a recent series of patients treated with radical cystectomy for bladder cancer
    Giacomo Novara
    Department of Urology, University of Verona, Italy
    Urol Int 75:10-6. 2005
    ..To identify the clinical and pathological prognostic factors in a homogeneous series of patients with bladder cancer who had undergone radical cystectomy in the late 1990s...
  26. doi request reprint Periorbital subcutaneous tumor-like lesion due to Dirofilaria repens
    Albino Eccher
    Anatomia Patologica, Dipartimento di Patologia, Universita di Verona, Italy
    Int J Surg Pathol 16:101-3. 2008
    ..The lesion did not recur for 5 months. Periorbital swelling can be rarely caused by Dirofilaria repens; therefore, this diagnosis should be considered in all cases of subcutaneous inflammatory or tumor-like lesion of unknown etiology...
  27. pmc True 3q chromosomal amplification in squamous cell lung carcinoma by FISH and aCGH molecular analysis: impact on targeted drugs
    Matteo Brunelli
    ISH Molecular Lab, Department of Pathology and Diagnostic, Azienda Ospedaliera Universitaria Integrata di Verona, University of Verona, Verona, Italy
    PLoS ONE 7:e49689. 2012
    ....
  28. doi request reprint Molecular pathology of lymphangioleiomyomatosis and other perivascular epithelioid cell tumors
    Guido Martignoni
    Department of Pathology, Universita di Verona, Italy
    Arch Pathol Lab Med 134:33-40. 2010
    ..3) genes with the regulation of the Rheb/m-TOR/p70S6K pathway. These data have opened a new era in the comprehension of the pathogenesis of LAM and have also suggested new therapeutic strategies for this potentially lethal disease...
  29. doi request reprint Primary pleomorphic rhabdomyosarcoma of the kidney in an adult
    Daniela Dalfior
    Anatomia Patologica, Dipartimento di Patologia, Universita di Verona, 37134 Verona, Italy
    Ann Diagn Pathol 12:301-3. 2008
    ..This is a very aggressive tumor with dismal prognosis. We report a new case of pleomorphic rhabdomyosarcoma of the kidney in an adult patient...
  30. ncbi request reprint Castration resistant prostate cancer (CRPC): state of the art, perspectives and new challenges
    Francesco Massari
    Medical Oncology, G B Rossi Academic Hospital, University of Verona, Piazzale L A Scuro 10, Verona, Italy
    Anticancer Agents Med Chem 13:872-86. 2013
    ..In this new therapeutic setting of CRPC, clinicians will have an opportunity to balance benefits and harms of these new agents in an individual context...
  31. doi request reprint Classical lobular breast carcinoma consistently lacks topoisomerase-IIα gene amplification: implications for the tailored use of anthracycline-based chemotherapies
    Eleonora Brunello
    Department of Pathology and Diagnostic, University of Verona, Italy
    Histopathology 60:482-8. 2012
    ..There is consistent lack of data focusing the topoisomerase-IIα gene status in lobular breast carcinoma, a subtype that usually shows poor responsiveness to chemotherapies including those using anthracycline drugs...
  32. doi request reprint HER-2/neu assessment in breast cancer using the original FDA and new ASCO/CAP guideline recommendations: impact on selecting patients for herceptin therapy
    Matteo Brunelli
    Department of Pathology, Universita di Verona, Verona, Italy
    Am J Clin Pathol 129:907-11. 2008
    ..The ASCO/CAP scheme has a great concordance coefficient between strong 3+ immunohistochemical cases and cases with high-grade, granular HER-2/neu amplification...
  33. ncbi request reprint Perivascular epithelioid cell tumor (PEComa) in the genitourinary tract
    Guido Martignoni
    Anatomia Patologica, Universita di Verona, Verona, Italy
    Adv Anat Pathol 14:36-41. 2007
    ..PEComas have been described in different organs and are considered ubiquitous tumors. In this review we discuss recent informations related to PEComas in the genitourinary tract...
  34. doi request reprint Subepithelial pelvic hematoma (Antopol--Goldman lesion) simulating renal neoplasm: report of a case and review of the literature
    Albino Eccher
    Department of Pathology, Ospedale Civile Maggiore, Verona, Italy
    Int J Surg Pathol 17:264-7. 2009
    ..Antopol-Goldman lesion should be kept in mind as a possible differential diagnosis of upper urinary tract lesion to avoid unnecessary nephrectomies. The anamnestic knowledge of amiloydosis may increase this diagnostic hypothesis...
  35. ncbi request reprint Short-term outcome after high-intensity focused ultrasound in the treatment of patients with high-risk prostate cancer
    Vincenzo Ficarra
    Department of Urology and Pathology, University of Verona, Italy
    BJU Int 98:1193-8. 2006
    ..To assess the short-term outcome in patients with high-risk prostate cancer treated by transrectal high-intensity focused ultrasound (HIFU)...
  36. ncbi request reprint Chondroid syringoma with extensive ossification
    Albino Eccher
    Anatomia Patologica, Dipartimento di Patologia, Universita di Verona, Strada Le Grazie No 8, 37134 Verona
    Int J Surg Pathol 15:385-7. 2007
  37. ncbi request reprint CD10 is expressed in a subset of chromophobe renal cell carcinomas
    Guido Martignoni
    Anatomia Patologica, Universita di Sassari, Sassari, Italy
    Mod Pathol 17:1455-63. 2004
    ..04). Parvalbumin was strongly expressed in all primary and metastatic chromophobe renal cell carcinomas. Western blot analysis was utilized to confirm the expression of both CD10 and parvalbumin in chromophobe renal cell carcinomas...
  38. ncbi request reprint Eosinophilic and classic chromophobe renal cell carcinomas have similar frequent losses of multiple chromosomes from among chromosomes 1, 2, 6, 10, and 17, and this pattern of genetic abnormality is not present in renal oncocytoma
    Matteo Brunelli
    Department of Pathology and Laboratory Medicine, Universita di Verona, Verona, Italy
    Mod Pathol 18:161-9. 2005
    ....
  39. ncbi request reprint Lymphatic and vascular embolizations are independent predictive variables of inguinal lymph node involvement in patients with squamous cell carcinoma of the penis: Gruppo Uro-Oncologico del Nord Est (Northeast Uro-Oncological Group) Penile Cancer data bas
    Vincenzo Ficarra
    Department of Urology, University of Verona, Verona, Italy
    Cancer 103:2507-16. 2005
    ....
  40. ncbi request reprint Oncocytoma-like angiomyolipoma. A clinicopathologic and immunohistochemical study of 2 cases
    Guido Martignoni
    Dipartimento di Patologia Sezione Anatomia Patologica, Universita di Verona, Verona, Italy
    Arch Pathol Lab Med 126:610-2. 2002
    ..Both patients are alive without recurrence 7 and 10 years after surgery, respectively. Based on clinical, morphologic, and immunophenotypic features, we conclude that these tumors are oncocytoma-like angiomyolipomas...
  41. ncbi request reprint Renal pathology in the tuberous sclerosis complex
    Guido Martignoni
    Anatomia Patologica, Universita di Sassari, Via G Matteotti 58, 07100 Sassari, Italy
    Pathology 35:505-12. 2003
  42. pmc A re-emerging marker for prognosis in hepatocellular carcinoma: the add-value of fishing c-myc gene for early relapse
    Federica Pedica
    Azienda Ospedaliera Universitaria Integrata di Verona, FISH Molecular Laboratory, Department of Pathology and Diagnostic, University of Verona, Verona, Italy
    PLoS ONE 8:e68203. 2013
    ....
  43. ncbi request reprint Predictive pathological factors of lymph nodes involvement in the squamous cell carcinoma of the penis
    Vincenzo Ficarra
    Department of Urology, University of Verona, Italy
    Int Urol Nephrol 34:245-50. 2002
    ..To evaluate the predictive role of primary tumor histopathological features in predicting inguinal lymph nodes involvement in patients with penile squamous cell carcinoma...
  44. doi request reprint Tertiary Gleason pattern 5 on needle biopsy predicts greater tumour volume on radical prostatectomy
    Matheesha Ranaweera
    Royal Adelaide Hospital, Adelaide, South Australia
    Pathology 43:693-6. 2011
    ..However, limited literature exists on the validity of this practice and the significance of tertiary Gleason patterns in needle biopsy...
  45. ncbi request reprint Small cell carcinoma of the bladder: a case report and a literature review
    Orietta Dalpiaz
    Department of Urology, University of Verona, Italy
    Arch Esp Urol 56:197-202. 2003
    ..To report a case of small cell carcinoma of the bladder. To analyse Literature data concerning disease stage, treatment and prognosis of small cell carcinoma of the bladder...
  46. ncbi request reprint Carcinoid tumors of the urinary bladder. Immunohistochemical study of 2 cases and review of the literature
    Guido Martignoni
    Dipartimento di Patologia Sezione Anatomia Patologica, Universita di Verona, Verona, Italy
    Arch Pathol Lab Med 127:e22-4. 2003
    ..In 1 of the tumors, 20% of the cells were positive for the beta subunit of human chorionic gonadotropin, and 20% were positive for thyroid transcription factor 1...
  47. ncbi request reprint Perivascular epithelioid cell (PEC) tumors of the uterus: a clinicopathologic study of two cases with aggressive features
    Luisanna Bosincu
    Anatomia Patologica, Universita di Sassari, Sassari, Italy
    Mod Pathol 18:1336-42. 2005
    ..Follow-up has shown the death of one patient whereas the other is alive without disease 36 months after the surgery. The two patients were evaluated for signs of tuberous sclerosis complex, and findings were negative...
  48. ncbi request reprint [Small cell carcinoma of the bladder. Report of 3 cases and review of the literature]
    Antonio Benito Porcaro
    Cattedra e Divisione Clinicizzata di Urologia, Ospedale Policlinico, Verona, Italy
    Arch Ital Urol Androl 74:142-5. 2002
    ..Herein we report on 3 cases of primary small cell carcinoma of the urinary biadder. We also review and update the literature concerning this topic...
  49. ncbi request reprint An unusual case of Cushing's syndrome due to ACTH-independent macronodular adrenal hyperplasia
    Sandra Rapetti
    Dipartimento di Scienze Mediche e Chirurgiche, Istituto di Medicina Interna, University of Verona, Verona
    Chir Ital 55:235-41. 2003
    ....
  50. doi request reprint Percutaneous and transureteral biopsies of renal papillae: safe and appropriate procedures for in vivo histologic analysis in stone formers
    Lorenzo Ruggera
    Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    J Endourol 25:25-30. 2011
    ....