Letizia Marsili

Summary

Affiliation: University of Siena
Country: Italy

Publications

  1. ncbi Theoretical models to evaluate hazard due to organochlorine compounds (OCs) in Mediterranean striped dolphin (Stenella coeruleoalba)
    L Marsili
    Dipartimento di Scienze Ambientali, Universita di Siena, G Sarfatti, Via Mattioli 4, 53100 Siena, Italy
    Chemosphere 56:791-801. 2004
  2. ncbi Dolphin Morbillivirus and Toxoplasma gondii coinfection in a Mediterranean fin whale (Balaenoptera physalus)
    Sandro Mazzariol
    Department of Comparative Biomedicine and Food Science, University of Padova, Agripolis Viale dell Università, 16, 35020 Legnaro, Italy
    BMC Vet Res 8:20. 2012
  3. ncbi Use of immunofluorescence technique in cultured fibroblasts from Mediterranean cetaceans as new "in vitro" tool to investigate effects of environmental contaminants
    Letizia Marsili
    Department of Environmental Sciences G Sarfatti, Siena University, Via Mattioli 4, Siena, Italy
    Mar Environ Res 66:151-3. 2008
  4. ncbi The Italian wall lizard (Podarcis sicula) as a bioindicator of oil field activity
    L Marsili
    Department of Environmental Sciences G Sarfatti, University of Siena, Via Mattioli 4, 53100 Siena, Italy
    Sci Total Environ 407:3597-604. 2009
  5. ncbi Polycyclic aromatic hydrocarbons (PaHs) in subcutaneous biopsies of Mediterranean cetaceans
    L Marsili
    Dip Scienze Ambientali, Universita di Siena, Italy
    Chemosphere 44:147-54. 2001
  6. ncbi Skin biopsies for cell cultures from Mediterranean free-ranging cetaceans
    L Marsili
    Department of Environmental Biology, Siena University, Siena, Italy
    Mar Environ Res 50:523-6. 2000
  7. ncbi Relationship between organochlorine contaminants and mixed function oxidase activity in skin biopsy specimens of Mediterranean fin whales (Balaenoptera physalus)
    L Marsili
    Dipartimento di Biologia Ambientale, Universita degli Studi di Siena, Italy
    Chemosphere 37:1501-10. 1998
  8. ncbi Evaluation of ecotoxicological effects of endocrine disrupters during a four-year survey of the Mediterranean population of swordfish (Xiphias gladius)
    M Cristina Fossi
    Department of Environmental Sciences, University of Siena, Via Mattioli 4, 53100 Siena, Italy
    Mar Environ Res 58:425-9. 2004
  9. ncbi A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico)
    Maria Cristina Fossi
    Department of Environmental Sciences, University of Siena, Via Mattioli 4, Siena, Italy
    Mar Environ Res 69:S17-20. 2010
  10. ncbi First detection of CYP1A1 and CYP2B induction in Mediterranean cetacean skin biopsies and cultured fibroblasts by Western blot analysis
    Maria Cristina Fossi
    Department of Environmental Sciences, Siena University, Via Mattioli 4, Siena, Italy
    Mar Environ Res 66:3-6. 2008

Detail Information

Publications26

  1. ncbi Theoretical models to evaluate hazard due to organochlorine compounds (OCs) in Mediterranean striped dolphin (Stenella coeruleoalba)
    L Marsili
    Dipartimento di Scienze Ambientali, Universita di Siena, G Sarfatti, Via Mattioli 4, 53100 Siena, Italy
    Chemosphere 56:791-801. 2004
    ..This evaluation was important for understanding differences in contaminant burden between males and females...
  2. ncbi Dolphin Morbillivirus and Toxoplasma gondii coinfection in a Mediterranean fin whale (Balaenoptera physalus)
    Sandro Mazzariol
    Department of Comparative Biomedicine and Food Science, University of Padova, Agripolis Viale dell Università, 16, 35020 Legnaro, Italy
    BMC Vet Res 8:20. 2012
    ..In particular, morbilliviral infection has been never described in the Mediterranean fin whale population...
  3. ncbi Use of immunofluorescence technique in cultured fibroblasts from Mediterranean cetaceans as new "in vitro" tool to investigate effects of environmental contaminants
    Letizia Marsili
    Department of Environmental Sciences G Sarfatti, Siena University, Via Mattioli 4, Siena, Italy
    Mar Environ Res 66:151-3. 2008
    ..Immunofluorescence was quantified with a specially designed Olympus macro, DetectIntZ. A major result was the possibility of using this "in vitro" assay to quantify induction of endogenous proteins...
  4. ncbi The Italian wall lizard (Podarcis sicula) as a bioindicator of oil field activity
    L Marsili
    Department of Environmental Sciences G Sarfatti, University of Siena, Via Mattioli 4, 53100 Siena, Italy
    Sci Total Environ 407:3597-604. 2009
    ..Results obtained validate, for the first time, P. sicula as a terrestrial bioindicator for the assessment of the toxicological impact of on-shore extraction activity...
  5. ncbi Polycyclic aromatic hydrocarbons (PaHs) in subcutaneous biopsies of Mediterranean cetaceans
    L Marsili
    Dip Scienze Ambientali, Universita di Siena, Italy
    Chemosphere 44:147-54. 2001
    ..w., respectively. The different PAH values between the two species can be attributed to the different positions they take in the Mediterranean food web. The sampling period significantly influenced PAH concentrations of fin whales...
  6. ncbi Skin biopsies for cell cultures from Mediterranean free-ranging cetaceans
    L Marsili
    Department of Environmental Biology, Siena University, Siena, Italy
    Mar Environ Res 50:523-6. 2000
    ..In particular, fibroblasts can be used to test the vulnerability of cetaceans and pinnipeds to different environmental contaminants such as organochlorine compounds, heavy metals and polycyclic aromatic hydrocarbons...
  7. ncbi Relationship between organochlorine contaminants and mixed function oxidase activity in skin biopsy specimens of Mediterranean fin whales (Balaenoptera physalus)
    L Marsili
    Dipartimento di Biologia Ambientale, Universita degli Studi di Siena, Italy
    Chemosphere 37:1501-10. 1998
    ..In this study PCBs and DDTs were evaluated in subcutaneous blubber and MFO activity in epidermis. An interesting correlation was found in male specimens between the two variables...
  8. ncbi Evaluation of ecotoxicological effects of endocrine disrupters during a four-year survey of the Mediterranean population of swordfish (Xiphias gladius)
    M Cristina Fossi
    Department of Environmental Sciences, University of Siena, Via Mattioli 4, 53100 Siena, Italy
    Mar Environ Res 58:425-9. 2004
    ..6 ppm d.w. These data indicate potential reproductive alterations in large pelagic fish and suggest the need for continuous monitoring to avoid reductions in the population of this fish species of high commercial and ecological interest...
  9. ncbi A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico)
    Maria Cristina Fossi
    Department of Environmental Sciences, University of Siena, Via Mattioli 4, Siena, Italy
    Mar Environ Res 69:S17-20. 2010
    ..The study revealed a higher level of toxicological stress in the Mediterranean fin whales...
  10. ncbi First detection of CYP1A1 and CYP2B induction in Mediterranean cetacean skin biopsies and cultured fibroblasts by Western blot analysis
    Maria Cristina Fossi
    Department of Environmental Sciences, Siena University, Via Mattioli 4, Siena, Italy
    Mar Environ Res 66:3-6. 2008
    ....
  11. ncbi Development of new-tools to investigate toxicological hazard due to endocrine disruptor organochlorines and emerging contaminants in Mediterranean cetaceans
    M Cristina Fossi
    Department of Environmental Sciences, Siena University, Via Mattioli 4, 53100 Siena, Italy
    Mar Environ Res 62:S200-4. 2006
    ....
  12. ncbi Endocrine Disruptors in Mediterranean top marine predators
    M Cristina Fossi
    Department of Environmental Sciences, University of Siena, Italy
    Environ Sci Pollut Res Int 13:204-7. 2006
    ..In this paper we review the final results of a project in which the hypothesis that Mediterranean top predator species (such as large pelagic fish and marine mammals) are potentially at risk due to EDs was investigated...
  13. ncbi Selection of reliable reference genes for qRT-PCR studies on cetacean fibroblast cultures exposed to OCs, PBDEs, and 17beta-estradiol
    Giacomo Spinsanti
    Department of Evolutionary Biology, University of Siena, Via A Moro 2, 53100 Siena SI, Italy
    Aquat Toxicol 87:178-86. 2008
    ....
  14. ncbi Genotoxic effects of produced waters in mosquito fish (Gambusia affinis)
    Ilaria Caliani
    Department of Environmental Sciences, University of Siena, Via Mattioli, 4, 53100, Siena, Italy
    Ecotoxicology 18:75-80. 2009
    ..A positive correlation between presence of micronucleated cells and PAH metabolites in bile was also observed...
  15. ncbi Assessment of toxicological status of a SW Mediterranean segment population of striped dolphin (Stenella coeruleoalba) using skin biopsy
    M Cristina Fossi
    Department of Environmental Sciences, University of Siena, P A Mattioli 4, 53100 Siena, Italy
    Mar Environ Res 58:269-74. 2004
    ..Skin biopsies of striped dolphins emerged as a suitable material for assessing the toxicological status of the various Mediterranean groups...
  16. ncbi Ecotoxicological diagnosis of striped dolphin (Stenella coeruleoalba) from the Mediterranean basin by skin biopsy and gene expression approach
    Cristina Panti
    Evolutionary Biology Department, University of Siena, Via A Moro 2, Siena, 53100, Italy
    Ecotoxicology 20:1791-800. 2011
    ..Our results suggest that this molecular approach applied to non-destructive biopsy material is a powerful diagnostic tool for evaluating ecotoxicological impact on cetacean populations...
  17. ncbi Application of a suite of biomarkers in Posidonia oceanica (L.) delile to assess the ecotoxicological impact on the coastal environment
    Daniela Bucalossi
    Department of Environmental Sciences, University of Siena, Via Mattioli 4, 53100 Siena, Italy
    Mar Environ Res 62:S327-31. 2006
    ..The results validated these biomarkers in posidonia for the assessment of ecotoxicological impact on the coastal ecosystem...
  18. ncbi The use of a non-lethal tool for evaluating toxicological hazard of organochlorine contaminants in Mediterranean cetaceans: new data 10 years after the first paper published in MPB
    M Cristina Fossi
    Department of Environmental Sciences, Siena University, Via delle Cerchia 3, Via Mattioli 4, 53100 Siena, Italy
    Mar Pollut Bull 46:972-82. 2003
    ..delphis. These results suggest that BPMO induction may be an early sign of exposure to organochlorine EDCs and can be used for periodic monitoring of Mediterranean marine mammal toxicological status...
  19. ncbi The role of large marine vertebrates in the assessment of the quality of pelagic marine ecosystems
    Maria Cristina Fossi
    Department of Environmental Sciences, University of Siena, Via P A Mattioli 4, 53100 Siena, Italy
    Mar Environ Res 77:156-8. 2012
    ..A theme that strongly emerged was the broad recognition that biomarkers offer real potential for the determination of good ecological status detecting the "undesirable biological effects" (indicator for descriptor 8)...
  20. ncbi Quantitative Real-Time PCR detection of TRPV1-4 gene expression in human leukocytes from healthy and hyposensitive subjects
    Giacomo Spinsanti
    Department of Evolutionary Biology, University of Siena, Siena, Italy
    Mol Pain 4:51. 2008
    ..While the expression of the TRPV1-4 genes has been adequately proved in skin, sensory fibres and keratinocytes, less is known about TRPV3 and TRPV4 expression in human blood cells...
  21. ncbi Potential toxicological hazard due to endocrine-disrupting chemicals on Mediterranean top predators: state of art, gender differences and methodological tools
    M C Fossi
    Department of Environmental Sciences, University of Siena, Via PA Mattioli 4, 53100 Siena, Italy
    Environ Res 104:174-82. 2007
    ..In cetaceans, male specimens showed higher cytochrome P450 induction (BPMO in skyn biopsies, CYP2B in fibroblasts cell cultures) by xenobiotics with respect to females...
  22. ncbi Use of biomarkers to investigate toxicological effects of produced water treated with conventional and innovative methods
    S Casini
    Department of Environmental Sciences, University of Siena, Via Mattioli 4, 53100 Siena, Italy
    Mar Environ Res 62:S347-51. 2006
    ..PW treated with zeolites (AIT) had the lowest toxicological impact. The results obtained applying this multi-biomarker approach suggest that the system using zeolites is effective for treating produced water...
  23. ncbi The use of porphyrins as a non-destructive biomarker of exposure to contaminants in two sea lion populations
    S Casin
    Department of Environmental Science, University of Siena, Italy
    Mar Environ Res 54:769-73. 2002
    ....
  24. ncbi Skin biopsy as a nondestructive tool for the toxicological assessment of endangered populations of pinnipeds: preliminary results on mixed function oxidase in Otaria flavescens
    M C Fossi
    Department of Environmental Biology, University of Siena, Italy
    Chemosphere 35:1623-35. 1997
    ..Organochlorines and polycyclic aromatic hydrocarbons can be analysed in subcutaneous fat and MFO activity (BPMO), Cyt.P450 isoforms, and DNA damage can be detected in epidermis...
  25. ncbi Are baleen whales exposed to the threat of microplastics? A case study of the Mediterranean fin whale (Balaenoptera physalus)
    Maria Cristina Fossi
    Department of Environmental Sciences, University of Siena, Via PA Mattioli 4, 53100 Siena, Italy
    Mar Pollut Bull 64:2374-9. 2012
    ..The results of this study represent the first warning of this emerging threat to baleen whales...
  26. ncbi Selection of reference genes for quantitative RT-PCR studies in striped dolphin (Stenella coeruleoalba) skin biopsies
    Giacomo Spinsanti
    Evolutionary Biology Department, University of Siena, Siena, Italy
    BMC Mol Biol 7:32. 2006
    ..A systematic evaluation of potential reference genes in cetacean skin biopsies is presented, in order to validate future qRT-PCR studies aiming at using the expression of selected genes as non-lethal biomarkers...