F Marrosu

Summary

Affiliation: University of Cagliari
Country: Italy

Publications

  1. ncbi request reprint Levetiracetam attenuates spontaneous spike-and-wave discharges in DBA/2J mice
    Francesco Marrosu
    Department of Neurological and Cardiovascular Sciences, University of Cagliari, Policlinico Universitario, S S 554 km 4 500, 09042 Monserrato CA, Italy
    Epilepsy Res 75:224-7. 2007
  2. ncbi request reprint Correlation between GABA(A) receptor density and vagus nerve stimulation in individuals with drug-resistant partial epilepsy
    Francesco Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Policlinico Universitario, Universita di Cagliari, SS 554 Bivio Sestu, 09042 Monserrato, Italy
    Epilepsy Res 55:59-70. 2003
  3. doi request reprint Combined EEG/fMRI recording in musicogenic epilepsy
    Francesco Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Universita degli Studi di Cagliari, Cagliari, Italy
    Epilepsy Res 84:77-81. 2009
  4. ncbi request reprint Increase in 20-50 Hz (gamma frequencies) power spectrum and synchronization after chronic vagal nerve stimulation
    F Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Policlinico Universitario, Universita di Cagliari, SS 554, Bivio Sestu, 09042 Monserrato, Italy
    Clin Neurophysiol 116:2026-36. 2005
  5. ncbi request reprint Beta and gamma range EEG power-spectrum correlation with spiking discharges in DBA/2J mice absence model: role of GABA receptors
    Francesco Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Universita di Cagliari, Monserrato, Italy
    Epilepsia 47:489-94. 2006
  6. ncbi request reprint Vagal nerve stimulation improves cerebellar tremor and dysphagia in multiple sclerosis
    F Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, University of Cagliari, Italy
    Mult Scler 13:1200-2. 2007
  7. ncbi request reprint Correlation between cerebral perfusion and hyperventilation enhanced focal spiking activity
    F Marrosu
    Institute of Neurology and Department of Nuclear Medicine, Faculty of Medicine, University of Cagliari, Via Ospedale, 54 09100, Cagliari, Italy
    Epilepsy Res 40:79-86. 2000
  8. doi request reprint Defective cerebral gamma-aminobutyric acid-A receptor density in patients with systemic lupus erythematosus and central nervous system involvement. An observational study
    A Mathieu
    Chair and AOU Unit of Rheumatology, University of Cagliari, Italy
    Lupus 19:918-26. 2010
  9. ncbi request reprint Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice
    Marco Bortolato
    Department of Neuroscience Bernard B Brodie, University of Cagliari, Cittadella Universitaria, S S 554 Km 4, 500, 09042, Monserrato CA, Italy
    Psychopharmacology (Berl) 194:361-9. 2007
  10. ncbi request reprint Vagal nerve stimulation effects on cerebellar tremor in multiple sclerosis
    F Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, University of Cagliari, Italy
    Neurology 65:490. 2005

Collaborators

  • M G Marrosu
  • M Piga
  • Marco Bortolato
  • G L Gessa
  • P Follesa
  • Giovanni Biggio
  • Giuliano Avanzini
  • L Dazzi
  • A Concas
  • M P Castelli
  • Italo Mocchetti
  • P Devoto
  • Cornelis Jan Stam
  • Monica Puligheddu
  • Antonella Tuveri
  • L Lorefice
  • P Solla
  • A Mathieu
  • Christian Cadeddu
  • Francesca Biggio
  • Roberto Frau
  • A Serra
  • S Tranquilli
  • M Rolesu
  • G Fenu
  • M R Murru
  • E Cocco
  • J Frau
  • G C Coghe
  • M Giagheddu
  • C Serra
  • A Boi
  • G Orofino
  • E Costantino
  • A Cannas
  • G L Floris
  • Silvio Nocco
  • G Porru
  • G Sanna
  • Antonella Muroni
  • A Cauli
  • Alberto Maleci
  • Martino Deidda
  • Giuseppe Mercuro
  • A Vacca
  • Pierluigi Olla
  • Cinzia Utzeri
  • Giorgio Gorini
  • Marco Orru
  • Pierina Zedda
  • Gian Benedetto B Melis
  • Anna Maria Paoletti
  • Maria Francesca Marotto
  • Cristiana Sogliano
  • Marisa OrrĂ¹
  • Giampaolo Mereu
  • Carla Marra
  • Jan C de Munck
  • Arent de Jongh
  • Jeroen Verbunt
  • Bob W van Dijk
  • Fabrizio Genugu
  • Antonio Giagheddu
  • Marcello Giagheddu
  • P Tacconi
  • A Giagheddu
  • L Satta
  • L Demelia
  • G Tamburini
  • P Siotto

Detail Information

Publications23

  1. ncbi request reprint Levetiracetam attenuates spontaneous spike-and-wave discharges in DBA/2J mice
    Francesco Marrosu
    Department of Neurological and Cardiovascular Sciences, University of Cagliari, Policlinico Universitario, S S 554 km 4 500, 09042 Monserrato CA, Italy
    Epilepsy Res 75:224-7. 2007
    ..p.), two classic antiabsence agents, LEV (50-200 mg/kg, i.p.) reduced the occurrence of spike-and-wave discharges, AE's typical electroencephalographic patterns. Our results confirm LEV's efficacy in AE treatment...
  2. ncbi request reprint Correlation between GABA(A) receptor density and vagus nerve stimulation in individuals with drug-resistant partial epilepsy
    Francesco Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Policlinico Universitario, Universita di Cagliari, SS 554 Bivio Sestu, 09042 Monserrato, Italy
    Epilepsy Res 55:59-70. 2003
    ..These results suggest that VNS may modulate the cortical excitability of brain areas associated with epileptogenesis and that GABA(A) receptor plasticity contributes to this effect...
  3. doi request reprint Combined EEG/fMRI recording in musicogenic epilepsy
    Francesco Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Universita degli Studi di Cagliari, Cagliari, Italy
    Epilepsy Res 84:77-81. 2009
    ..Furthermore, rCBF modifications in other regions suggest that additional aspects of musical processing are also elicited during musicogenic seizures...
  4. ncbi request reprint Increase in 20-50 Hz (gamma frequencies) power spectrum and synchronization after chronic vagal nerve stimulation
    F Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Policlinico Universitario, Universita di Cagliari, SS 554, Bivio Sestu, 09042 Monserrato, Italy
    Clin Neurophysiol 116:2026-36. 2005
    ..The objective of the present study is to investigate how VNS affects local and inter regional syncronization in different frequencies in pharmaco-resistant partial epilepsy...
  5. ncbi request reprint Beta and gamma range EEG power-spectrum correlation with spiking discharges in DBA/2J mice absence model: role of GABA receptors
    Francesco Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Universita di Cagliari, Monserrato, Italy
    Epilepsia 47:489-94. 2006
    ..To describe the correlations between spiking pattern and EEG power spectrum frequency in DBA/2J mice, a model for murine absence seizures, after gamma-aminobutyric acid (GABA)(B) modulation...
  6. ncbi request reprint Vagal nerve stimulation improves cerebellar tremor and dysphagia in multiple sclerosis
    F Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, University of Cagliari, Italy
    Mult Scler 13:1200-2. 2007
    ..The results obtained suggest an additional therapeutic application for VNS and may represent a novel form of treatment in patients with severe MS...
  7. ncbi request reprint Correlation between cerebral perfusion and hyperventilation enhanced focal spiking activity
    F Marrosu
    Institute of Neurology and Department of Nuclear Medicine, Faculty of Medicine, University of Cagliari, Via Ospedale, 54 09100, Cagliari, Italy
    Epilepsy Res 40:79-86. 2000
    ..This study suggests a correlation between localized increase in rCBP and HPV-induced IELDs and provides a tool to discuss uncommon aspects of the physiology of rCBP during the inter-ictal state in the epileptogenic areas...
  8. doi request reprint Defective cerebral gamma-aminobutyric acid-A receptor density in patients with systemic lupus erythematosus and central nervous system involvement. An observational study
    A Mathieu
    Chair and AOU Unit of Rheumatology, University of Cagliari, Italy
    Lupus 19:918-26. 2010
    ..This study may support the concept that cognitive impairment in systemic lupus erythematosus could be the outcome of fine-tuned neurotransmission alterations...
  9. ncbi request reprint Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice
    Marco Bortolato
    Department of Neuroscience Bernard B Brodie, University of Cagliari, Cittadella Universitaria, S S 554 Km 4, 500, 09042, Monserrato CA, Italy
    Psychopharmacology (Berl) 194:361-9. 2007
    ..We previously reported that baclofen, the prototypical GABA(B) agonist, elicits antipsychotic-like effects in the rat paradigm of prepulse inhibition (PPI) of the startle, a highly validated animal model of schizophrenia...
  10. ncbi request reprint Vagal nerve stimulation effects on cerebellar tremor in multiple sclerosis
    F Marrosu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, University of Cagliari, Italy
    Neurology 65:490. 2005
  11. doi request reprint Cardiovascular modulation during vagus nerve stimulation therapy in patients with refractory epilepsy
    Christian Cadeddu
    Dept of Cardiovascular and Neurological Sciences, University of Cagliari, Sardinia, Italy
    Epilepsy Res 92:145-52. 2010
    ....
  12. doi request reprint Brain MRI and SPECT in the diagnosis of early neurological involvement in Wilson's disease
    Mario Piga
    Nuclear Medicine, Department of Medical Science, Policlinico Universitario, University of Cagliari, Cagliari, Italy
    Eur J Nucl Med Mol Imaging 35:716-24. 2008
    ..To evaluate the impact of brain MRI and single-photon emission computed tomography (SPECT) in early detection of central nervous system abnormalities in patients affected by Wilson's disease (WD) with or without neurological involvement...
  13. ncbi request reprint Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain
    Paolo Follesa
    Department of Experimental Biology, Section of Neuroscience, University of Cagliari, Cagliari, Italy
    Brain Res 1179:28-34. 2007
    ..These new findings contribute to the elucidation of the molecular mechanisms underlying the therapeutic actions of vagus nerve stimulation in both treatment-resistant depression and epilepsy...
  14. doi request reprint A genetic study of the FMR1 gene in a Sardinian multiple sclerosis population
    L Lorefice
    Department of Public Health and Clinical and Molecular Medicine, Multiple Sclerosis Center, University of Cagliari, Ospedale Binaghi, Via Is Guadazzonis, 2, 09126, Cagliari, Italy
    Neurol Sci 36:2213-20. 2015
    ..Our results do not support a possible role for premutation or gray zone alleles in MS Sardinian patients. Further studies are needed to better understand the relationship between FXTAS and MS...
  15. doi request reprint Behavioral, neuropsychiatric and cognitive disorders in Parkinson's disease patients with and without motor complications
    P Solla
    Movement Disorders Center, Institute of Neurology, University of Cagliari, Cagliari, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 35:1009-13. 2011
    ..The factors affecting MC and these non-motor symptoms are still largely unknown and their interactions are not yet fully evaluated...
  16. ncbi request reprint Age distribution of MEG spontaneous theta activity in healthy subjects
    Monica Puligheddu
    Dipartimento di Scienze Neurologiche e Cardiovascolari, Universita di Cagliari, Monserrato Cagliari, Italy
    Brain Topogr 17:165-75. 2005
    ..Whether the prevalent posterior distribution of theta is the expression of distinct networks or the outcome of complex dynamics are questions of possible relevance in the organization of higher order processes...
  17. doi request reprint Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy
    Antonella Tuveri
    Department of Cardiovascular and Neurological Sciences, University of Cagliari, Cagliari, Italy
    Epilepsia 49:1221-9. 2008
    ..Following these studies it seems of interest to investigate possible variations, among other hormonal parameters, of THDOC and DHEAS in CE patients...
  18. doi request reprint Involvement of GABA in mirror focus: a case report
    Marco Bortolato
    Department of Neurological and Cardiovascular Sciences, University of Cagliari, Monserrato CA, Italy
    Epilepsy Res 90:300-3. 2010
    ..These results extend previous evidence on the involvement of GABAergic signaling in MF pathophysiology...
  19. pmc Chronic vagus nerve stimulation induces neuronal plasticity in the rat hippocampus
    Francesca Biggio
    Department of Experimental Biology, Centre of Excellence for the Neurobiology of Dependence, University of Cagliari, Cagliari, Italy
    Int J Neuropsychopharmacol 12:1209-21. 2009
    ..However, these changes were not associated with evident behavioural alterations characteristic of an antidepressant or anxiolytic action...
  20. ncbi request reprint Comparison of MRI, EEG, EPs and ECD-SPECT in Wilson's disease
    M Giagheddu
    Clinica Neurologica, Policlinico Universitario, Universita degli Studi di Cagliari, Italy
    Acta Neurol Scand 103:71-81. 2001
    ..CONCLUSION: We highlight the use of this interesting procedure in the therapeutic monitoring of this disease...
  21. doi request reprint Antipsychotic-like properties of 5-alpha-reductase inhibitors
    Marco Bortolato
    Department of Neuroscience Bernard B Brodie, University of Cagliari, Monserrato, Cagliari, Italy
    Neuropsychopharmacology 33:3146-56. 2008
    ..p.) induced no catalepsy in either the bar test or the paw test. Our results suggest that 5AR inhibitors elicit antipsychotic-like effects in animals and may be proposed as a putative novel target in the management of psychotic disorders...
  22. doi request reprint Sleep deprivation disrupts prepulse inhibition of the startle reflex: reversal by antipsychotic drugs
    Roberto Frau
    Department of Neuroscience Bernard B Brodie, University of Cagliari, Italy
    Int J Neuropsychopharmacol 11:947-55. 2008
    ..Our data suggest that SD induces gating deficits that might be relevant to the hallucinatory phenomena observed in humans, and provide a novel reliable animal model where such relationship can be studied...
  23. ncbi request reprint Epilepsia partialis continua in cat scratch disease
    Monica Puligheddu
    Department of Cardiovascular and Neurological Sciences, University of Cagliari, SS 554, Bivio Sestu, 09042 Monserrato, Cagliari, Italy
    Seizure 13:191-5. 2004
    ..Magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT) and back-averaged EEG data recorded during myoclonic activity document this CSD complication...