Federica Marini

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308
    Federica Marini
    University of Pittsburgh Cancer Institute, Hillman Cancer Center, Research Pavilion, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 278:32014-9. 2003
  2. ncbi DNA nucleotide excision repair-dependent signaling to checkpoint activation
    Federica Marini
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy
    Proc Natl Acad Sci U S A 103:17325-30. 2006
  3. ncbi Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation
    Sarah Sertic
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, 20133 Milano, Italy
    Proc Natl Acad Sci U S A 108:13647-52. 2011
  4. ncbi Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways
    Diego M Muzzini
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy
    DNA Repair (Amst) 7:941-50. 2008
  5. ncbi Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex
    Emanuela Tumini
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy
    DNA Repair (Amst) 10:149-58. 2011
  6. ncbi A human DNA helicase homologous to the DNA cross-link sensitivity protein Mus308
    Federica Marini
    University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15261, USA
    J Biol Chem 277:8716-23. 2002

Collaborators

Detail Information

Publications6

  1. ncbi POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308
    Federica Marini
    University of Pittsburgh Cancer Institute, Hillman Cancer Center, Research Pavilion, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 278:32014-9. 2003
    ..GFP-tagged recombinant POLN had DNA polymerase activity on activated calf thymus DNA and on a singly primed template...
  2. ncbi DNA nucleotide excision repair-dependent signaling to checkpoint activation
    Federica Marini
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy
    Proc Natl Acad Sci U S A 103:17325-30. 2006
    ..Inhibition of RNA polymerase II transcription significantly reduces the phosphorylation of key checkpoint factors in XP/CS fibroblasts on exposure to UV damage...
  3. ncbi Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation
    Sarah Sertic
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, 20133 Milano, Italy
    Proc Natl Acad Sci U S A 108:13647-52. 2011
    ..These findings reveal a key role for hEXO1 in the UV-induced DNA damage response linking NER to checkpoint activation in human cells...
  4. ncbi Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways
    Diego M Muzzini
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy
    DNA Repair (Amst) 7:941-50. 2008
    ..While hel-308 functions in a Fanconi anemia-dependent pathway, polq-1 has a role in a novel distinct and brc-1 (CeBRCA1)-dependent ICL repair process in metazoans...
  5. ncbi Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex
    Emanuela Tumini
    Dipartimento di Scienze Biomolecolari e Biotecnologie, Universita degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy
    DNA Repair (Amst) 10:149-58. 2011
    ..However, depletion of PSF2 is not sufficient to reduce monoubiquitylation of FANCD2 or its localization to nuclear foci following DNA damage. Our results suggest a novel crosstalk between DNA replication and the FA pathway...
  6. ncbi A human DNA helicase homologous to the DNA cross-link sensitivity protein Mus308
    Federica Marini
    University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15261, USA
    J Biol Chem 277:8716-23. 2002
    ..Activity was supported by ATP or dATP but not other nucleotide triphosphates. The enzyme translocates on DNA with 3' to 5' polarity and behaves as a multimer upon gel filtration...