I Maremmani

..This topic required further examination among heroin abusers because cocaine abuse is commonly comorbid with heroin abuse...

..To describe the prevalence and the risk factors of suicidal ideation in a cohort of Italian opioid addicts presenting for treatment...

..We therefore submit that the present conceptualization of the link between bipolar spectrum and addictive disorders has not only heuristic and scientific values, but also an important message for the clinician...

..There is considerable uncertainty in the current literature about the relationship between personality dimensions and affective temperaments...

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..These data indicate that chronic, psychosis, whether associated with past or with current use of cannabis, is frequently associated with bipolar spectrum disorders and tends to display less blunted affect and more clastic behavior...

..Our integrated model especially accounts for the issue of mood disorders as the a weightsome psychic substrate for the development of a substance-resorting attitude...

..By contrast, the depressive temperament seemed to mute the expression of mania into a depressive-manic phenomenology...

..CONCLUSION: The emerging multidimensional structure of phobia is congruent with, and further enriches, the existing literature...

..This correlation has implications for treatment and research strategies on the aetiology within a subpopulation of OCD...

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..Despite several research reports on incongruent psychotic features in mania, whether such features define a distinct disorder is unsettled...

..Much of the literature has described personality disorder constructs for heroin addicts. Building on previous work we examine the relevance of affective temperament measures in these patients...

..This should be accounted for when deciding on take-home policies and issues of potential methadone diversion...

..CONCLUSIONS: This study supports the hypothesis that mood, anxiety and impulse-control dysregulation are the core of the clinical phenomenology of addiction and should be incorporated into its nosology...

..Valproate appears to be a potentially fruitful medication to study in these dual diagnosis patients due to preliminary evidence demonstrating its anticraving efficacy...

..This latter pattern seems to result in an increased risk for fatal accidental overdoses. The use of these longer-acting agents in women may be influenced by psychosocial and hormonal factors...

..Thus, depressive traits seem to increase sensitivity to suffering, cyclothymic traits appear relevant to creativity, and hyperthymic traits have been implicated in territoriality and leadership and more generally in active pursuits...

..The aim of this study was to compare the long-term outcomes of treatment-resistant heroin addicts with and without DSM-IV axis I psychiatric comorbidity (dual diagnosis)...

..This study suggests the long-term efficacy of methadone treatment and buprenorphine treatment on symptoms of opioid addiction and quality of life...

..Literature on this topic is still scarce, although this was a matter of debate since several decades...

..Cessation of illicit opioid abuse and retention in treatment are positively correlated with decrease in alcohol and cocaine abuse and the absence of the psychosocial complications associated with such abuse...

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..Although methadone remains an essential maintenance therapy option, buprenorphine-based regimens increase access to care and provide safer, more appropriate treatment than methadone for some patients...

..A six-times/daily fractionated administration of the GHB dose was the only significant predictor of the retention rate...

..Results show a direct relationship between cocaine abuse and a higher rate of psychiatric disorders, but a negative correlation with the severity of self-rated psychopathology...

..The cyclothymic disposition turned out to be the most 'morbid', and associated with both internalizing and externalizing disturbances...