Luca Manetti

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. doi request reprint Usefulness of salivary cortisol in the diagnosis of hypercortisolism: comparison with serum and urinary cortisol
    Luca Manetti
    Department of Endocrinology and Metabolism, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 168:315-21. 2013
  2. doi request reprint Serum pituitary antibodies in normal pregnancy and in patients with postpartum thyroiditis: a nested case-control study
    Luca Manetti
    Department of Endocrinology, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 159:805-9. 2008
  3. ncbi request reprint Prevalence and functional significance of antipituitary antibodies in patients with autoimmune and non-autoimmune thyroid diseases
    Luca Manetti
    Dipartimento di Endocrinologia, Universita di Pisa, Ospedale Cisanello, Via Paradisa, 2, Pisa, Italy
    J Clin Endocrinol Metab 92:2176-81. 2007
  4. ncbi request reprint Serum prostate-specific antigen concentration is increased in acromegalic women
    L Manetti
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    J Endocrinol Invest 27:643-7. 2004
  5. doi request reprint Changes in coagulation indexes and occurrence of venous thromboembolism in patients with Cushing's syndrome: results from a prospective study before and after surgery
    Luca Manetti
    Department of Endocrinology, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 163:783-91. 2010
  6. ncbi request reprint Thyroid function differently affects serum cystatin C and creatinine concentrations
    L Manetti
    Department of Endocrinology, University of Pisa, Ospedale di Cisanello, Italy
    J Endocrinol Invest 28:346-9. 2005
  7. ncbi request reprint Undetectable inferior petrosal sinus levels of PTH-related peptide (PTHrP) in patients with ACTH-dependent Cushing's disease
    L Manetti
    Department of Endocrinology, University of Pisa, Italy
    J Endocrinol Invest 28:819-21. 2005
  8. doi request reprint Growth hormone is necessary for the p53-mediated, obesity-induced insulin resistance in male C57BL/6J x CBA mice
    Fausto Bogazzi
    MD, PhD, Department of Clinical and Experimental Medicine, Section of Endocrinology, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy or
    Endocrinology 154:4226-36. 2013
  9. doi request reprint Comparison of the effects of primary somatostatin analogue therapy and pituitary adenomectomy on survival in patients with acromegaly: a retrospective cohort study
    Fausto Bogazzi
    Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 169:367-76. 2013
  10. pmc Tumor infiltrating lymphocytes but not serum pituitary antibodies are associated with poor clinical outcome after surgery in patients with pituitary adenoma
    Isabella Lupi
    Department of Endocrinology and Metabolism, University of Pisa, 56124 Pisa, Italy
    J Clin Endocrinol Metab 95:289-96. 2010

Detail Information

Publications31

  1. doi request reprint Usefulness of salivary cortisol in the diagnosis of hypercortisolism: comparison with serum and urinary cortisol
    Luca Manetti
    Department of Endocrinology and Metabolism, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 168:315-21. 2013
    ..The aims of the study were: i) to evaluate the performance of salivary cortisol (SC) in hypercortisolism and ii) to compare SC with serum cortisol (SeC) and urinary cortisol...
  2. doi request reprint Serum pituitary antibodies in normal pregnancy and in patients with postpartum thyroiditis: a nested case-control study
    Luca Manetti
    Department of Endocrinology, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 159:805-9. 2008
    ..The aim of this study was to evaluate antipituitary antibody (APA) prevalence in a series of patients with postpartum thyroiditis (PPT) during pregnancy and in the postpartum...
  3. ncbi request reprint Prevalence and functional significance of antipituitary antibodies in patients with autoimmune and non-autoimmune thyroid diseases
    Luca Manetti
    Dipartimento di Endocrinologia, Universita di Pisa, Ospedale Cisanello, Via Paradisa, 2, Pisa, Italy
    J Clin Endocrinol Metab 92:2176-81. 2007
    ..Circulating antipituitary antibodies (APA) are markers of autoimmune hypophysitis, which may cause deficient pituitary function. The prevalence of APA in autoimmune thyroid disorders (AITD) is uncertain...
  4. ncbi request reprint Serum prostate-specific antigen concentration is increased in acromegalic women
    L Manetti
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    J Endocrinol Invest 27:643-7. 2004
    ..However, the observation that M women still have higher serum PSA levels than controls suggest that in acromegaly PSA is regulated not only by androgens but also by the GH/IGF-I system itself...
  5. doi request reprint Changes in coagulation indexes and occurrence of venous thromboembolism in patients with Cushing's syndrome: results from a prospective study before and after surgery
    Luca Manetti
    Department of Endocrinology, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 163:783-91. 2010
    ..To evaluate whether patients with Cushing's syndrome (CS) had i) changes in coagulative and fibrinolytic parameters associated with CS activity and ii) higher prevalence of venous thromboembolic events (VTE)...
  6. ncbi request reprint Thyroid function differently affects serum cystatin C and creatinine concentrations
    L Manetti
    Department of Endocrinology, University of Pisa, Ospedale di Cisanello, Italy
    J Endocrinol Invest 28:346-9. 2005
    ..However, the observation that hyper- or hypothyroid patients have normal serum Cys C levels limits its use as a marker of peripheral thyroid hormone effect...
  7. ncbi request reprint Undetectable inferior petrosal sinus levels of PTH-related peptide (PTHrP) in patients with ACTH-dependent Cushing's disease
    L Manetti
    Department of Endocrinology, University of Pisa, Italy
    J Endocrinol Invest 28:819-21. 2005
    ..Our data, combined with others reported in literature, indicate that PTHrP release by ACTH-secreting tumors is not a common occurrence. Therefore, we conclude that IPS and peripheral PTHrP are of little clinical usefulness...
  8. doi request reprint Growth hormone is necessary for the p53-mediated, obesity-induced insulin resistance in male C57BL/6J x CBA mice
    Fausto Bogazzi
    MD, PhD, Department of Clinical and Experimental Medicine, Section of Endocrinology, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy or
    Endocrinology 154:4226-36. 2013
    ..On the contrary, Lean mice were unaffected by changes of GH action. GH seems to be necessary for the increased adipose p53 expression and for insulin resistance of obese mice. ..
  9. doi request reprint Comparison of the effects of primary somatostatin analogue therapy and pituitary adenomectomy on survival in patients with acromegaly: a retrospective cohort study
    Fausto Bogazzi
    Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Eur J Endocrinol 169:367-76. 2013
    ..Acromegalic patients have an increased risk of mortality. The objective of this study was to compare the effect of different therapies for acromegaly on mortality...
  10. pmc Tumor infiltrating lymphocytes but not serum pituitary antibodies are associated with poor clinical outcome after surgery in patients with pituitary adenoma
    Isabella Lupi
    Department of Endocrinology and Metabolism, University of Pisa, 56124 Pisa, Italy
    J Clin Endocrinol Metab 95:289-96. 2010
    ..Serum pituitary antibodies (Pit Abs) and tumor-infiltrating lymphocytes (TILs) have been described in pituitary adenomas, but their clinical significance remains unknown...
  11. ncbi request reprint Submandibular salivary gland volume is increased in patients with acromegaly
    Luca Manetti
    Department of Endocrinology and Metabolism, University of Pisa, Italy
    Clin Endocrinol (Oxf) 57:97-100. 2002
    ..Acromegaly is characterized by an enlargement of various organs. The aim of the present study was to evaluate whether acromegalic patients have an increased volume of submandibular salivary glands...
  12. doi request reprint Cardiac extrinsic apoptotic pathway is silent in young but activated in elder mice overexpressing bovine GH: interplay with the intrinsic pathway
    Fausto Bogazzi
    Department of Endocrinology and Metabolism, University of Pisa, Ospedale Cisanello, Via Paradisa, 2, 56124 Pisa, Italy
    J Endocrinol 210:231-8. 2011
    ....
  13. ncbi request reprint Thyroid color flow Doppler sonography: an adjunctive tool for differentiating patients with inappropriate thyrotropin (TSH) secretion due to TSH-secreting pituitary adenoma or resistance to thyroid hormone
    Fausto Bogazzi
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    Thyroid 16:989-95. 2006
    ..Thyrotropin (TSH)-secreting pituitary adenoma (TSHoma) and resistance to thyroid hormone (RTH) are two forms of inappropriate TSH secretion. Thyroid blood flow is largely TSH dependent...
  14. ncbi request reprint Abnormal expression of PPAR gamma isoforms in the subcutaneous adipose tissue of patients with Cushing's disease
    Fausto Bogazzi
    Department of Endocrinology, University of Pisa, Italy
    Clin Endocrinol (Oxf) 66:7-12. 2007
    ..Peroxisome proliferators-activated receptor (PPAR)gamma is the master regulator of adipogenesis; however, the expression of PPARgamma isoforms in the subcutaneous adipose tissue (SAT) of patients with Cushing's disease is unknown...
  15. doi request reprint Impact of different cut-off limits of peak GH after GHRH-arginine stimulatory test, single IGF1 measurement, or their combination in identifying adult patients with GH deficiency
    Fausto Bogazzi
    Department of Endocrinology and Metabolism, University of Pisa, Ospedale Cisanello, 56124 Pisa, Italy
    Eur J Endocrinol 164:685-93. 2011
    ..To evaluate the impact of different peak GH cut-off limits after GHRH-Arg test, IGF1 measurement, or their combination in identifying patients with GH deficit (GHD)...
  16. doi request reprint Regulation of cardiac fatty acids metabolism in transgenic mice overexpressing bovine GH
    Fausto Bogazzi
    Department of Endocrinology and Metabolism, University of Pisa, Ospedale Cisanello, Pisa, Italy
    J Endocrinol 201:419-27. 2009
    ..In conclusion, chronic GH excess increased FA metabolism in the young age, whereas its action was overwhelmed in elder ages likely by GH-independent mechanisms, leading to reduced expression of key enzyme of FA metabolism...
  17. ncbi request reprint Identification of acromegalic patients at risk of developing colonic adenomas
    Fausto Bogazzi
    Dipartimento di Endocrinologia e Metabolismo, Universita di Pisa, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    J Clin Endocrinol Metab 91:1351-6. 2006
    ..Acromegaly seems to be associated with an increased prevalence of colonic adenomas, although factors affecting their development and recurrence of the latter are not fully known...
  18. ncbi request reprint Comparison of the effectiveness and tolerability of intravenous or oral glucocorticoids associated with orbital radiotherapy in the management of severe Graves' ophthalmopathy: results of a prospective, single-blind, randomized study
    C Marcocci
    Dipartimento di Endocrinologia e Metabolismo, Ortopedia e Traumatologia, Medicina del Lavoro, University of Pisa, 56124 Pisa, Italy
    J Clin Endocrinol Metab 86:3562-7. 2001
    ....
  19. ncbi request reprint Thyroid vascularity is increased in patients with active acromegaly
    Fausto Bogazzi
    Department of Endocrinology and Metabolism, University of Pisa, Italy
    Clin Endocrinol (Oxf) 57:65-70. 2002
    ..To determine whether acromegalic patients have increased thyroidal vascularity and blood flow on colour flow Doppler sonography (CFDS)...
  20. ncbi request reprint The course of Graves' ophthalmopathy is not influenced by near total thyroidectomy: a case-control study
    C Marcocci
    Dipartimento di Endocrinologia e Metabolismo, Ortopedia e Traumatologia, Medicina del Lavoro, Pisa, Italy
    Clin Endocrinol (Oxf) 51:503-8. 1999
    ..Although controversial, radioiodine may be followed by progression of eye disease, preventable by glucocorticoid administration. Whether thyroidectomy affects the course of ophthalmopathy is uncertain...
  21. ncbi request reprint Graves' ophthalmopathy and 131I therapy
    C Marcocci
    Department of Endocrinology and Metabolism, University of Pisa, Italy
    Q J Nucl Med 43:307-12. 1999
    ..Glucocorticoid treatment should be limited, in our opinion, to patients with clinically evident eye disease and to those without ophthalmopathy but with other known risk factors, such as smoking...
  22. ncbi request reprint Soluble interleukin-1 receptor antagonist concentration in patients with Graves' ophthalmopathy is neither related to cigarette smoking nor predictive of subsequent response to glucocorticoids
    L Bartalena
    Dipartimento di Endocrinologia e Metabolismo, Ortopedia e Traumatologia, Medicina del Lavoro, University of Pisa, Pisa, Italy
    Clin Endocrinol (Oxf) 52:647-51. 2000
    ..The aim of the present study was to evaluate serum soluble interleukin-1 receptor antagonist (sIL-1RA) concentration and its relationship with the degree of cigarette smoking in patients with Graves' ophthalmopathy (GO)...
  23. ncbi request reprint Increased frequency of euthyroid ophthalmopathy in patients with Graves' disease associated with myasthenia gravis
    M Marino
    Department of Endocrinology, University of Pisa, Italy
    Thyroid 10:799-802. 2000
    ....
  24. ncbi request reprint Cigarette smoking and treatment outcomes in Graves ophthalmopathy
    L Bartalena
    University of Pisa, Italy
    Ann Intern Med 129:632-5. 1998
    ..It is unclear whether smoking affects the course of Graves ophthalmopathy and therapeutic outcomes...
  25. ncbi request reprint Cabergoline therapy and the risk of cardiac valve regurgitation in patients with hyperprolactinemia: a meta-analysis from clinical studies
    F Bogazzi
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    J Endocrinol Invest 31:1119-23. 2008
    ....
  26. doi request reprint Treatment with low doses of cabergoline is not associated with increased prevalence of cardiac valve regurgitation in patients with hyperprolactinaemia
    F Bogazzi
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    Int J Clin Pract 62:1864-9. 2008
    ..The aim of the study was to evaluate whether HyperPRL patients treated with dopamine agonists had a higher prevalence of cardiac valves regurgitation than that of general population...
  27. doi request reprint Serum insulin-like growth factor-1 concentrations are reduced in severely obese women and raise after weight loss induced by laparoscopic adjustable gastric banding
    Giulia Galli
    Endocrinology Unit, University Hospital of Pisa, Pisa, Italy
    Obes Surg 22:1276-80. 2012
    ..Obesity is associated with abnormalities of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis. The role of serum IGF-1 measurement for recognition of hypothalamic-pituitary diseases in obesity is still a matter of debate...
  28. ncbi request reprint Prostate-specific antigen is increased in female patients with Cushing's disease
    L Manetti
    Department of Endocrinology and Metabolism, University of Pisa, Italy
    J Endocrinol Invest 25:RC29-31. 2002
    ..6, p<0.05). In conclusion, elevated serum PSA values are markers of androgen activity in female with Cushing's disease and their normalization may represent an additional index of remission of the disease...
  29. ncbi request reprint Prevalence of thyroid diseases in patients with acromegaly: results of an Italian multi-center study
    M Gasperi
    Department of Endocrinology, University of Pisa, Italy
    J Endocrinol Invest 25:240-5. 2002
    ..Thyroid volume, evaluated by ultrasonography, was correlated to the estimated duration of acromegaly. Finally, the prevalence of thyroid carcinoma was slightly increased than in the general population...
  30. ncbi request reprint Microvascular density and vascular endothelial growth factor expression in normal pituitary tissue and pituitary adenomas
    P Viacava
    Department of Oncology, Section of Pathology, University of Pisa, Pisa, Italy
    J Endocrinol Invest 26:23-8. 2003
    ..VEGF expression is however well preserved in adenomas and this might contribute to adequate tumoral vascular supply with complex mechanisms other than endothelial cells proliferation...
  31. ncbi request reprint Early effects of methylprednisolone infusion on serum cystatin C in patients with severe Graves' ophthalmopathy
    Luca Manetti
    Clin Chim Acta 356:227-8. 2005