Research Topics
| C MaffeisSummaryAffiliation: University of Verona Country: Italy Publications
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Publications
Diet macronutrient composition reported before treatment predicts BMI change in obese children: the role of lipidsC Maffeis
Unit of Pediatric Diabetes, Clinical Nutrition and Obesity, Department of Sciences of Life and Reproduction, University of Verona, Verona, Italy
Eur J Clin Nutr 66:1066-8. 2012....
Pro-atherogenic postprandial profile: Meal-induced changes of lipoprotein sub-fractions and inflammation markers in obese boysC Maffeis
Regional Center for Juvenile Diabetes, Department of Sciences of Life and Reproduction, Section of Pediatrics, University of Verona, 37134 Verona, Italy Electronic address
Nutr Metab Cardiovasc Dis 22:959-65. 2012..The aim of this study is to investigate postprandial metabolic response, lipoprotein oxidation and circulating cytokine levels, after the ingestion of two different meals with different fat/carbohydrate ratio...
Breakfast skipping in prepubertal obese children: hormonal, metabolic and cognitive consequencesC Maffeis
Unit of Pediatric Diabetes, Clinical Nutrition and Obesity, Department of Life and Reproduction Sciences, University of Verona, Verona, Italy
Eur J Clin Nutr 66:314-21. 2012..The aim of our study was to investigate the relationship between the variation of hormonal and metabolic postprandial parameters induced by breakfast consumption or fasting and cognitive performance in obese children...
Diet, physical, and biochemical characteristics of children and adolescents with type 1 diabetes: relationship between dietary fat and glucose controlClaudio Maffeis
Department of Sciences of Life and Reproduction, Regional Center for Pediatric Diabetes, University of Verona, Verona, Italy
Pediatr Diabetes 13:137-46. 2012..Aims: To assess dietary intake, cardiovascular risk factors, and the association between diet composition and glycemic control in Italian youth with T1D...
Effects of dinner composition on postprandial macronutrient oxidation in prepubertal girlsClaudio Maffeis
Department of Pediatrics, University of Verona, Polyclinic G B Rossi, Piazza L A Scuro 6, 34134 Verona, Italy
Obes Res 12:1128-35. 2004..To see whether a fat-rich (50%) evening meal promoted fat oxidation and a different spontaneous food intake on the following day at breakfast than a meal with a lower fat content (20%) in 10 prepubertal obese girls...
Prevalence of overweight and obesity in 2- to 6-year-old Italian childrenClaudio Maffeis
Department of Mother and Child, Biology Genetics, Pediatrics Section, University of Verona, Piazza LA Scuro 10, 37134 Verona, Italy
Obesity (Silver Spring) 14:765-9. 2006..To assess the prevalence of overweight and obesity in 2- to 6-year-old Italian children and to compare the prevalence between the north and the south of the country...
Nutrient oxidation during moderately intense exercise in obese prepubertal boysC Maffeis
Department of Pediatrics, University of Verona, Piazzale L Scuro, 37134 Verona, Italy
J Clin Endocrinol Metab 90:231-6. 2005..Increasing the exercise intensity did not promote fat oxidation. Therefore, walking at a speed of 4 km/h is recommended as practicable exercise for obese boys and, consequently, for the treatment of childhood obesity...
A high-fat vs. a moderate-fat meal in obese boys: nutrient balance, appetite, and gastrointestinal hormone changesClaudio Maffeis
Regional Center for Juvenile Diabetes, Department of Mother and Child, Biology Genetics, Section of Pediatrics, University of Verona, Verona, Italy
Obesity (Silver Spring) 18:449-55. 2010..Gastrointestinal hormones were not related to clinically assessed hunger suppression after both meals...
Fat cell size, insulin sensitivity, and inflammation in obese childrenClaudio Maffeis
Department of Mother and Child, Biology Genetics, Section of Pediatrics, University of Verona, Verona, Italy
J Pediatr 151:647-52. 2007..To assess the association between adiposity indexes (body mass index [BMI], fat mass, adipocyte size) and circulating inflammation markers with known metabolic relevance or insulin sensitivity in overweight/obese children...
Could the savory taste of snacks be a further risk factor for overweight in children?C Maffeis
Department of Mother and Child, Biology Genetics, Section of Pediatrics, University of Verona, Verona, Italy
J Pediatr Gastroenterol Nutr 46:429-37. 2008..The quantity, type and composition of snack foods may play a role in the development and maintenance of obesity in children. A high consumption of energy-dense snacks may promote fat gain...
Physical activity in the prevention and treatment of childhood obesity: physio-pathologic evidence and promising experiencesClaudio Maffeis
Department of Mother and Child, Biology Genetics, Section of Pediatrics, Regional Center for Juvenile Diabetes, University of Verona, Verona, Italy
Int J Pediatr Obes 3:29-32. 2008..Nevertheless, further studies are still necessary to design more effective preventive and treatment programs for childhood obesity...
Ghrelin, insulin sensitivity and postprandial glucose disposal in overweight and obese childrenClaudio Maffeis
Department of Mother and Child, Biology Genetics, Unit of Pediatrics, University of Verona, P le L A Scuro 10, 37 134 Verona, Italy
Eur J Endocrinol 154:61-8. 2006..To explore the changes of ghrelin circulating levels induced by a mixed meal and their relationship with postprandial substrate oxidation rates in overweight and obese children with different levels of insulin sensitivity...
Insulin resistance is a risk factor for high blood pressure regardless of body size and fat distribution in obese childrenC Maffeis
Department of Mother and Child, Biology Genetics, University of Verona, Verona, Italy
Nutr Metab Cardiovasc Dis 20:266-73. 2010..The prevalence of children with hypertension is increasing, especially in obese children. This study was to assess the relationship between blood pressure, indexes of adiposity, body fat distribution and insulin resistance...
Adipocytes IGFBP-2 expression in prepubertal obese childrenMaffeis Claudio
Regional Centre for Juvenile Diabetes, Section of Obesity and Clinical Nutrition, Department of Mother and Child, Biology Genetics, University of Verona, Verona, Italy
Obesity (Silver Spring) 18:2055-7. 2010..IGFBP-2 expression may potentially be one of the local mechanisms used by adipocytes to limit further fat gain...
Teaching children with diabetes about adequate dietary choicesClaudio Maffeis
Section of Pediatrics, Department of Mother and Child, Biology Genetics, University of Verona, Piazza LA Scuro 10, Verona 37134, Italy
Br J Nutr 99:S33-9. 2008..A good balance between eating for pleasure and maintaining one's health is a challenge for anyone. Appropriate nutritional education helps children with diabetes to find this balance and enjoy a better quality of life...
Insulin resistance and the persistence of obesity from childhood into adulthoodClaudio Maffeis
Department of Pediatrics, University of Verona, 37134 Verona, Italy
J Clin Endocrinol Metab 87:71-6. 2002..In conclusion, obesity tracks into adulthood for many obese Caucasian children. In obese girls, insulin resistance during childhood appears to oppose the risk of obesity in adulthood...
Fasting plasma glucose (FPG) and the risk of impaired glucose tolerance in obese children and adolescentsClaudio Maffeis
Regional Centre for Juvenile Diabetes, Department of Mother and Child, Biology Genetics, Section of Pediatrics, University of Verona, Verona, Italy
Obesity (Silver Spring) 18:1437-42. 2010..A gender/puberty independent cutoff of FPG may be considered a screening tool to narrow clinical indication to OGTT in obese white children and adolescents...
Prevention of obesity in childhoodC Maffeis
Department of Pediatrics, University Hospital, University of Verona, Italy
J Endocrinol Invest 25:919-21. 2002
Physical activity: an effective way to control weight in children?Claudio Maffeis
Department of Mother and Child, Biology Genetics, Pediatrics Section, University of Verona, Verona, Italy
Nutr Metab Cardiovasc Dis 17:394-408. 2007..Also of interest is the analysis of available evidence that justifies the recommendation of physical activity programs in the treatment of childhood obesity...
Circulating ghrelin levels in girls with central precocious puberty are reduced during treatment with LHRH analogClaudio Maffeis
Department of Mother and Child, Biology Genetics, Section of Pediatrics, Endocrinology Unit, University of Verona, P le L A Scuro, 10, 37134 Verona, Italy
Eur J Endocrinol 156:99-103. 2007..Decreased levels of ghrelin have been measured in growing children during puberty. No data are available for girls with central precocious puberty (CPP)...
Insulin sensitivity is correlated with subcutaneous but not visceral body fat in overweight and obese prepubertal childrenClaudio Maffeis
Department of Mother and Child, Biology Genetics, Section of Pediatrics, University of Verona, Piazzale L A Scuro 10, Verona, Italy
J Clin Endocrinol Metab 93:2122-8. 2008....
Waist circumference and cardiovascular risk factors in prepubertal childrenC Maffeis
Department of Pediatrics, University of Verona, Polyclinic, Verona, Italy
Obes Res 9:179-87. 2001..Few data on the relationship between body-fat distribution and cardiovascular risk factors are available in children, especially before puberty...
Meal-induced thermogenesis and obesity: is a fat meal a risk factor for fat gain in children?C Maffeis
Department of Pediatrics, University of Verona, 37134 Verona, Italy
J Clin Endocrinol Metab 86:214-9. 2001..Therefore, diet composition per se must be taken into account among the various risk factors that induce obesity in children...
Does waist circumference predict fat gain in children?C Maffeis
Department of Pediatrics, University of Verona, Polyclinic, Verona, Italy
Int J Obes Relat Metab Disord 25:978-83. 2001..The aim of this study was to identify in a group of 8-y-old prepubertal children the anthropometric parameter with the highest prediction power of overweight, measured 4 y later...
Substrate metabolism, nutrient balance and obesity development in children and adolescents: a target for intervention?M Sun
Department of Pediatrics, University of Verona, Polyclinic, Verona, Italy
Obes Rev 5:183-8. 2004..Several future directions are addressed, such that a combination of increased physical activity and modification in diet composition, in terms of energy density and glycemic index, is recommended for children and adolescents...
[Definition of obesity in childhood: criteria and limits]A Luciano
Ospedale Maggiore di Verona, Verona, Italy
Minerva Pediatr 55:453-9. 2003..However, in agreement with Cole et al., the choice to use the BMI cut-offs centiles passing through the adult BMI cut-off of 30, is reasonable. However, it is always preferable to use population specific BMI reference tables...
Genetic analysis carried out on blood-spots of phenylalanine hydroxylase-deficient newborns detected by northeastern Italian neonatal screeningM Zaffanello
Department of Paediatrics, University of Verona, 37134 Verona, Italy
Genet Test 9:133-7. 2005..Consequently, the genotype/phenotype correlation could lead to a more accurate diagnosis and prognosis for families...
Long-term effects of childhood obesity on morbidity and mortalityC Maffeis
Department of Pediatrics, University of Verona, Italy
Horm Res 55:42-5. 2001..The association between childhood obesity and adult morbidity and mortality strongly suggests that a more effective prevention and treatment of childhood obesity should be pursued...
Waist circumference as a predictor of cardiovascular and metabolic risk factors in obese girlsC Maffeis
Childhood Obesity Group of the Italian Society of Pediatric Endocrinology and Diabetology, Italy
Eur J Clin Nutr 57:566-72. 2003..to assess the clinical relevance of waist circumference in identifying girls with higher cardiovascular risk across puberty...
Waist-to-height ratio, a useful index to identify high metabolic risk in overweight childrenClaudio Maffeis
Department of Mother and Child, Biology Genetics, Pediatric Unit, University of Verona, Verona, Italy
J Pediatr 152:207-13. 2008..To determine whether using a combination of body mass index (BMI) and waist circumference (WC) or waist-to-height ratio (W/Hr) is clinically helpful in identifying children with high metabolic and cardiovascular risks...
Childhood obesity: potential mechanisms for the development of an epidemicClaudio Maffeis
Department of Mother and Child, Biology-Genetics, Unit of Pediatrics, University of Verona, Verona, Italy
Nestle Nutr Workshop Ser Pediatr Program 57:31-43; discussion 43-50. 2006
Neonatal birth parameters of positive newborns at PKU screening as predictors of false-positive and positive results at recall-testingMarco Zaffanello
Regional Centre of Neonatal Screening for Inborn Erros of Metabolism and Department of Paediatrics, University of Verona, Verona, Italy
J Med Screen 10:181-3. 2003..A total of 38 PKU neonates (17 males and 21 females) diagnosed between 1990 and 2001 were used as positive-controls...
Urological complications and copper replacement therapy in childhood Menkes syndromeMarco Zaffanello
Department of Mother and Child, Biology Genetics, Section of Paediatrics, University of Verona, Verona, Italy
Acta Paediatr 95:785-90. 2006..Urological complications are frequent in Menkes syndrome, a very rare X-linked recessive disorder of copper (Cu) metabolism...
Allergenicity of a hydrolyzed rice infant formula in a guinea pig modelGiorgio L Piacentini
Clinica Pediatrica, Universita di Verona, Verona, Italy
Ann Allergy Asthma Immunol 91:61-4. 2003..Because sensitization to cow's milk is a common finding in children, the identification of safe alternative protein sources is important in the management of childhood allergy...
Obesity and inflammation: evidence for an elementary lesionAndrea Sbarbati
Department of Morphological Biomedical Sciences, University Hospital, University of Verona, Verona, Italy
Pediatrics 117:220-3. 2006..These preliminary results suggest that additional studies should be designed to clarify the cause of adipocyte fragility in obese children...
Multiple positive results during a neonatal screening program: a retrospective analysis of incidence, clinical implications and outcomesMarco Zaffanello
Department of Pediatrics, University of Verona, Italy
J Perinat Med 33:246-51. 2005....
Body size and early growth in appropriate- and large-for-gestational-age infantsM Sun
Department of Paediatrics, University of Verona, Polyclinic, Verona, Italy
Acta Paediatr 92:1127-32. 2003..05). CONCLUSION: Early growth from birth to 5 mo of life is significantly affected by body size and adiposity at birth. Fatter newborns had a slower growth rate than thinner newborns...
Aetiology of overweight and obesity in children and adolescentsC Maffeis
Department of Paediatrics, University of Verona, Polyclinic B Roma, Italy
Eur J Pediatr 159:S35-44. 2000..CONCLUSION: Further research is needed to identify new risk factors of childhood obesity, both in the genetic and environmental areas, which may help to develop more effective strategies for the prevention and treatment of obesity...
Body fat and insulin resistance independently predict increased serum C-reactive protein in hyperandrogenic women with polycystic ovary syndromeFlavia Tosi
Endocrinology and Metabolism, Department of Biomedical and Surgical Sciences, University of Verona, 37126 Verona, Italy
Eur J Endocrinol 161:737-45. 2009..The aims of this study were to assess whether increased serum CRP is a specific feature of PCOS and to investigate the mechanisms underlying this association...
The relationship between body mass index and body size dissatisfaction in young adolescents: spline function analysisSamuele Cortese
Child Neuropsychiatry Unit, G B Rossi Hospital, Department of Mother Child and Biology Genetics, Verona University, Verona, Italy
J Am Diet Assoc 110:1098-102. 2010..459). Because average weight and slightly underweight young girls desired a thinner body, our study suggests that these subgroups should receive particular attention in public health programs as well as in dietetics clinical practice...
Neonatal hyperinsulinemic hypoglycemia. Two case reportsM Zaffanello
Regional Centre for Neonatal Congenital Errors of Metabolism, University of Verona, Verona, Italy
Minerva Pediatr 54:325-33. 2002..Persistent hypoglycemic or epileptic-like episodes, in particular on waking up, after meals or during banal infections, must be studied to reveal hyperinsulinism...
The relationship between body size and depression symptoms in adolescentsSamuele Cortese
Child Neuropsychiatry Unit, G B Rossi Hospital, Verona, Italy
J Pediatr 154:86-90. 2009..To evaluate the relationship between body size and depressive symptoms, as well as the moderating effects of age, sex, and socioeconomic status (SES), in a sample of young adolescents...
[Multifactorial prevention of obesity: the role of physical fitness]C Maffeis
Dipartimento Materno Infantile e di Biologia-Genetica, Sezione Pediatria, , Verona, Italy
Minerva Pediatr 59:567-8. 2007
Parent reports of sleep/alertness problems and ADHD symptoms in a sample of obese adolescentsSamuele Cortese
Child Neuropsychiatry Unit, Department of Mother Child and Biology Genetics, G B Rossi Hospital, Verona University, Verona, Italy
J Psychosom Res 63:587-90. 2007..The aim of this study was to assess the relationship between parent reports of sleep/alertness problems and ADHD traits in a clinical sample of obese adolescents, controlling for symptoms of anxiety/depression...
Level of physical activity and adiposity in children: relevance of sedentary behaviorsClaudio Maffeis
Am J Clin Nutr 81:1449; author reply 1449-50. 2005
Snacking and obesity: urgency of a definition to explore such a relationshipDario Gregori
J Am Diet Assoc 107:562; discussion 562-3. 2007
Relationship between immigration fluxes and patterns of small for gestational age in ItalyClaudio Maffeis
Acta Paediatr 94:986-8. 2005
Increased incidence of urinary tract infections in patients with coeliac diseaseVassilios Fanos
Pediatr Nephrol 17:570-1. 2002
Attention-deficit/hyperactivity disorder (ADHD) and obesity: a systematic review of the literatureSamuele Cortese
AP HP, Child and Adolescent Psychopathology Unit, Robert Debre Hospital, Paris VII University, Paris, France
Crit Rev Food Sci Nutr 48:524-37. 2008..This might allow a more appropriate clinical management and, ultimately, a better quality of life for patients with both obesity and ADHD...
