Research Topics
| S LucchiariSummaryAffiliation: University of Milan Country: Italy Publications
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Detail Information
Publications
Hepatic and neuromuscular forms of glycogenosis type III: nine mutations in AGLS Lucchiari
Dino Ferrari Center, Department of Neurological Sciences, University of Milan, Fondazione I R C C S Ospedale Maggiore Policlinico, Mangialli, Regina Elena, Milan, Italy
Hum Mutat 27:600-1. 2006..664+3A>G was also detected in two patients, both homozygous. The present work is yet another confirmation that the individual genetic background plays a pivotal role in influencing the phenotypes, as occurs in other metabolic diseases...
Colocalization of ribonuclear inclusions with muscle blind like-proteins in a family with myotonic dystrophy type 2 associated with a short CCTG expansionS Lucchiari
Centro Dino Ferrari, Dipartimento di Scienze Neurologiche, Universita degli Studi di Milano, Fondazione I R C C S Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Italy
J Neurol Sci 275:159-63. 2008..This is one of the smallest expansion reported and the shortest with the evidence of nuclear foci. These data contribute to the clinical and molecular correlation of ZNF9 gene short expansion...
Molecular characterisation of GSD III subjects and identification of six novel mutations in AGLS Lucchiari
Dino Ferrari Centre, Department of Neurological Sciences, University of Milan, I.R.C.C.S. Policlinico, Milan, Italy
Hum Mutat 20:480. 2002..Consequently, the strategy of mutation finding based on screening of recurrent common mutations is limited, as far as regards Italian GSD III patients, to check for the presence of IVS21(+1) G>A...
Mutational analysis of the AGL gene: five novel mutations in GSD III patientsS Lucchiari
Dino Ferrari Centre, Department of Neurological Sciences, University of Milan, I.R.C.C.S. Policlinico, Milan, Italy
Hum Mutat 22:337. 2003..R428K, c.3911 insA, p.G1087R and c.3512_3549dup+c.3512_3519del. The functional relevance of these mutations is discussed on the basis of the recently acquired knowledge about the boundaries and structures of the two catalytic domains...
Clinical and genetic variability of glycogen storage disease type IIIa: seven novel AGL gene mutations in the Mediterranean areaS Lucchiari
Centro Dino Ferrari, Dipartimento di Scienze Neurologiche, Universita' degli Studi di Milano, I.R.C.C.S. Ospedale Maggiore Policlinico, Milano, Italy
Am J Med Genet 109:183-90. 2002..Our data confirm the extreme genetic heterogeneity of this disease, thus precluding a strategy of mutation finding based on screening of recurrent common mutations...
Clinical, biochemical and genetic features of glycogen debranching enzyme deficiencyS Lucchiari
Dino Ferrari Centre, Department of Neurological Sciences, University of Milan, I R C C S Foundation Ospedale Maggiore Policlinico Mangiagalli and Regina Elena, Milan, Italy
Acta Myol 26:72-4. 2007..This report reviews current clinical and molecular knowledge about this disorder and describes the variability at phenotype and genotype levels of a large group of Italian GSDIII patients...
Optimized detection of DNA point mutations by double gradient denaturing gradient gel electrophoresisL Cremonesi
I R C C S, H San Raffaele, Unità di Genetica e Diagnostica Molecolare, Milan, Italy
Clin Chem Lab Med 36:959-61. 1998....
Beta-enolase deficiency, a new metabolic myopathy of distal glycolysisG P Comi
Istituto di Clinica Neurologica, Universita degli Studi di Milano, IRCCS, Ospedale Maggiore Policlinico, Italy
Ann Neurol 50:202-7. 2001..Muscle beta-enolase deficiency should be considered in the differential diagnosis of metabolic myopathies due to inherited defects of distal glycolysis...
