Research Topics
| P LoiSummaryAffiliation: University of Teramo Country: Italy Publications
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Detail Information
Publications
Genetic rescue of an endangered mammal by cross-species nuclear transfer using post-mortem somatic cellsP Loi
Department of Structure, Functions, Animal Pathology and Biotechnology, University of Teramo, Italy
Nat Biotechnol 19:962-4. 2001..Our findings support the use of cloning for the expansion of critically endangered populations...- Nuclei of nonviable ovine somatic cells develop into lambs after nuclear transplantationPasqualino Loi
Dipartimento di Strutture, Funzioni, Patologie e Biotecnologie, Università di Teramo, Piazza Aldo Moro 45, 64100 Teramo, Italy
Biol Reprod 67:126-32. 2002.... - Amphibian and mammal somatic-cell cloning: different species, common results?Pasqualino Loi
Department of Comparative Biomedical Sciences, Teramo University, Teramo 64100, Italy
Trends Biotechnol 21:471-3. 2003.... 
Review paper: a review of the pathology of abnormal placentae of somatic cell nuclear transfer clone pregnancies in cattle, sheep, and miceC Palmieri
Department of Comparative Biomedical Sciences, Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy
Vet Pathol 45:865-80. 2008..The purpose of this review is to provide an overview of the anatomic pathology of abnormal placentae of SCNT clones and to summarize current knowledge concerning underlying pathogenetic mechanisms...- Nuclear transfer of freeze-dried somatic cells into enucleated sheep oocytesP Loi
Department of Comparative Biomedical Sciences, Teramo University, Teramo, Italy
Reprod Domest Anim 43:417-22. 2008.... - High levels of anandamide, an endogenous cannabinoid, block the growth of sheep preimplantation embryos by inducing apoptosis and reversible arrest of cell proliferationM Y Turco
Department of Comparative Biomedical Sciences, University of Teramo 64100, Teramo, Italy
Hum Reprod 23:2331-8. 2008..We wanted to know whether the endocannabinoid signalling system was present also in the sheep reproductive tract and which kind of effect(s) AEA had on the development of sheep blastocysts in vitro... - Oocyte maturation is required for correct sperm chromatin rearrangementM Mattioli
, Italy
Vet Res Commun 28:205-8. 2004 - Intracoelomic teratoma in a domestic duck (Anas platyrhynchos domesticus): a case report including immunohistochemistry and electron microscopyC Palmieri
Department of Comparative Biomedical Sciences, Faculty of Veterinary Medicine, Teramo University, Piazza Aldo Moro 45, 64100 Teramo, Italy
Res Vet Sci 93:862-4. 2012.... - Placental abnormalities in ovine somatic cell clones at term: a light and electron microscopic investigationC Palmieri
Department of Comparative Biomedical Sciences, Faculty of Veterinary Medicine, Teramo University, Piazza Aldo Moro 45, 64100 Teramo, Italy
Placenta 28:577-84. 2007.... 
The effect of interspecific oocytes on demethylation of sperm DNANathalie Beaujean
Division of Gene Expression and Development, Roslin Institute, Roslin EH25 9PS, United Kingdom
Proc Natl Acad Sci U S A 101:7636-40. 2004..Our results suggest that the murine demethylation process is facilitated either by a sperm-derived factor or by male pronuclear chromatin composition...- Preservation of the wild European mouflon: the first example of genetic management using a complete program of reproductive biotechnologiesGrazyna Ptak
Dipartimento di Strutture, Funzioni e Patologie degli Animali e Biotecnologie, Università di Teramo, 64100 Teramo, Italy
Biol Reprod 66:796-801. 2002..In addition, a genetic resource bank for the European mouflon was established, with cryopreserved sperm, embryos, and somatic cells... - Improving delivery and offspring viability of in vitro-produced and cloned sheep embryosGrazyna Ptak
Dipartimento di Biotecnologie, Università di Teramo, Italy
Biol Reprod 67:1719-25. 2002.... - Asymmetric nuclear reprogramming in somatic cell nuclear transfer?Pasqualino Loi
Department of Comparative Biomedical Sciences, Teramo, Italy
Bioessays 30:66-74. 2008.... - Development of sheep androgenetic embryos is boosted following transfer of male pronuclei into androgenetic hemizygotesKazutsugu Matsukawa
Department of Comparative Biomedical Sciences, University of Teramo, Italy
Cloning Stem Cells 9:374-81. 2007..In conclusion, pronuclear transfer is an effective method to produce sheep androgenetic blastocysts... - Cloning of endangered mammalian species: any progress?Pasqualino Loi
Department of Comparative Biomedical Sciences, Piazza Aldo Moro 45, 64100, Teramo, Italy
Trends Biotechnol 25:195-200. 2007.... - Developmental and functional evidence of nuclear immaturity in prepubertal oocytesGrazyna Ptak
Department of Comparative Biomedical Sciences, University of Teramo, Teramo, Italy
Hum Reprod 21:2228-37. 2006..The nuclear compartment has been proposed as responsible for the developmental arrest of prepubertal mouse oocytes while the studies on prepubertal sheep and cow oocyte model suggested the cytoplasm immaturity accounts for this failure... - Cold-induced calcium elevation triggers DNA fragmentation in immature pig oocytesMauro Mattioli
Dipartimento di Strutture, Funzioni e Patologie Animali e Biotecnologie, Fisiologia Veterinaria, Università di Teramo, Italy
Mol Reprod Dev 65:289-97. 2003..The addition of inhibitors of ryanodine dependent Ca(2+) stores may represent a valuable protective treatment to reduce chilling injuries... - Placental abnormalities associated with post-natal mortality in sheep somatic cell clonesPasqualino Loi
Dipartimento di Scienze Biomediche Comparate, Teramo University, Piazza Aldo Moro 45, 64100 Teramo, Italy
Theriogenology 65:1110-21. 2006..Our results strongly suggest that post-mortality in cloned lambs is mainly caused by placental abnormalities... - Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transferLorraine E Young
School of Human Development, University of Nottingham, Queens Medical Centre, Nottingham, UK
Mech Dev 120:1433-42. 2003..Although the underlying mechanisms remain to be determined, our data indicate that somatic cell nuclear transfer procedures can lead to epigenetic deregulation at imprinted loci... - Nucleus transfer in mammals: noninvasive approaches for the preparation of cytoplastsJosef Fulka
Institute of Animal Production, POB 1, Prague 10, Czech Republic
Trends Biotechnol 22:279-83. 2004..For this reason the simplification of this step is permanently in the centre of interest of those scientists who are involved in the production of clones... - Leukaemia inhibitory factor enhances sheep fertilization in vitro via an influence on the oocyteGrazyna Ptak
Department of Comparative Biomedical Science, University of Teramo, 64100 Teramo, Italy
Theriogenology 65:1891-9. 2006..Together, these data demonstrate that LIF exerts a beneficial effect on sheep oocytes and embryos in vitro, but only at stages concomitant with steroid hormones surges... - The absence of a DNA replication checkpoint in porcine zygotesIrena Vackova
Institute of Animal Production, POB 1, CS 104 01 Prague 114, Czech Republic
Zygote 14:33-7. 2006..We conclude that in porcine zygotes there is an absence of the DNA replication checkpoint that is typical for some other mammals... - Donor-dependent developmental competence of oocytes from lambs subjected to repeated hormonal stimulationGrazyna Ptak
Dipartimento di Scienze Biomediche Comparate, Università di Teramo, 64100 Teramo, Italy
Biol Reprod 69:278-85. 2003..This observation consents to predict the ovarian performance from a single ewe already in early prepuberty (i.e., to qualify the female to breeding programs)... - Cybrid human embryos--warranting opportunities to augment embryonic stem cell researchJosef Fulka
Institute of Animal Science, Prague, Czech Republic
Trends Biotechnol 26:469-74. 2008..If this approach is to be successful, many biological questions need to be answered and, in addition, some moral and ethical aspects must be taken into account...