Giuseppe Lippi

Summary

Affiliation: University of Verona
Country: Italy

Publications

  1. doi request reprint Reduced von Willebrand factor-cleaving protease levels in secondary thrombotic microangiopathies and other diseases
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy
    Semin Thromb Hemost 33:787-97. 2007
  2. doi request reprint Lipaemic donations: truth and consequences
    Giuseppe Lippi
    Unità Operativa di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy Electronic address
    Transfus Apher Sci 49:181-4. 2013
  3. doi request reprint Vitamin D concentration and deficiency across different ages and genders
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Aging Clin Exp Res 24:548-51. 2012
  4. doi request reprint Pathophysiology, clinics, diagnosis and treatment of heart involvement in carbon monoxide poisoning
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Biochem 45:1278-85. 2012
  5. doi request reprint Laboratory medicine and sports: between Scylla and Charybdis
    Giuseppe Lippi
    U O di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Chem Lab Med 50:1309-16. 2012
  6. doi request reprint Canine olfactory detection of cancer versus laboratory testing: myth or opportunity?
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Chem Lab Med 50:435-9. 2012
  7. doi request reprint Evaluation of the analytical performances of the novel Beckman Coulter AU5800
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Italy
    Clin Biochem 45:502-4. 2012
  8. doi request reprint Doping and thrombosis in sports
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 37:918-28. 2011
  9. doi request reprint Genetic and biochemical heterogeneity of cardiac troponins: clinical and laboratory implications
    Giuseppe Lippi
    Section of Clinical Chemistry, University Hospital of Verona, Verona, Italy
    Clin Chem Lab Med 47:1183-94. 2009
  10. doi request reprint Mental depression and cardiovascular disease: a multifaceted, bidirectional association
    Giuseppe Lippi
    Dipartimento di Scienze Morfologico Biomediche, Universita di Verona, Italy
    Semin Thromb Hemost 35:325-36. 2009

Detail Information

Publications150 found, 100 shown here

  1. doi request reprint Reduced von Willebrand factor-cleaving protease levels in secondary thrombotic microangiopathies and other diseases
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy
    Semin Thromb Hemost 33:787-97. 2007
    ..This latter issue will be critically addressed in this review article. In addition, the published literature evaluating plasma ADAMTS-13 levels in other pathologic conditions different from TMA will also be discussed...
  2. doi request reprint Lipaemic donations: truth and consequences
    Giuseppe Lippi
    Unità Operativa di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy Electronic address
    Transfus Apher Sci 49:181-4. 2013
    ..Transfusion medicine should thereby embark on a landmark effort to find a universal agreement of behaviours and harmonization of policies worldwide. ..
  3. doi request reprint Vitamin D concentration and deficiency across different ages and genders
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Aging Clin Exp Res 24:548-51. 2012
    ..The aim of the present study was to assess the concentration as well as the mild and moderate deficiencies of 25-hydroxyvitamin D (25OHD) across different ages and genders...
  4. doi request reprint Pathophysiology, clinics, diagnosis and treatment of heart involvement in carbon monoxide poisoning
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Biochem 45:1278-85. 2012
    ..No specific treatment other than oxygen delivery can be advocated for cardiac toxicity at present, and 100% oxygen therapy should be continued until the patient is asymptomatic and carboxyhemoglobin levels decrease below 5-10%...
  5. doi request reprint Laboratory medicine and sports: between Scylla and Charybdis
    Giuseppe Lippi
    U O di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Chem Lab Med 50:1309-16. 2012
    ..Finally, the wide armamentarium of laboratory tests represents the milestone for identifying cheating athletes in the strenuous fight against doping in sports...
  6. doi request reprint Canine olfactory detection of cancer versus laboratory testing: myth or opportunity?
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Chem Lab Med 50:435-9. 2012
    ..This article is aimed to provide an overview of the available data on cancer sniffer dogs, highlighting the appealing perspectives and the potential drawbacks...
  7. doi request reprint Evaluation of the analytical performances of the novel Beckman Coulter AU5800
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Italy
    Clin Biochem 45:502-4. 2012
    ..To assess the analytical performance of Beckman Coulter AU5800...
  8. doi request reprint Doping and thrombosis in sports
    Giuseppe Lippi
    UO Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 37:918-28. 2011
    ..The present article provides an overview on the epidemiological association as well as the underlying biochemical and biological mechanisms linking the practice of doping in sports with the development of thrombosis...
  9. doi request reprint Genetic and biochemical heterogeneity of cardiac troponins: clinical and laboratory implications
    Giuseppe Lippi
    Section of Clinical Chemistry, University Hospital of Verona, Verona, Italy
    Clin Chem Lab Med 47:1183-94. 2009
    ....
  10. doi request reprint Mental depression and cardiovascular disease: a multifaceted, bidirectional association
    Giuseppe Lippi
    Dipartimento di Scienze Morfologico Biomediche, Universita di Verona, Italy
    Semin Thromb Hemost 35:325-36. 2009
    ..This article aims to review the biological and clinical links between depression and cardiovascular disease...
  11. ncbi request reprint Influence of the sample matrix on the stability of beta-CTX at room temperature for 24 and 48 hours
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Italy
    Clin Lab 53:455-9. 2007
    ..In conclusion, the results of our investigation demonstrate that EDTA plasma is the most suitable sample matrix for the storage of beta-CTX at room temperature after centrifugation...
  12. doi request reprint Proteomic analysis of venous thromboembolism
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Strada Abbeveratoia 14, 43100 Parma, Italy
    Expert Rev Proteomics 7:275-82. 2010
    ....
  13. ncbi request reprint Measurement of Elecsys NT-proBNP in serum, K2 EDTA and heparin plasma
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, 37134 Verona, Italy
    Clin Biochem 40:747-8. 2007
    ..There is controversial evidence on a matrix influence on the measurement of NT-proBNP...
  14. doi request reprint Prostate-specific antigen-based screening for prostate cancer in the third millennium: useful or hype?
    Giuseppe Lippi
    Section of Clinical Chemistry, University Hospital of Verona, Verona, Italy
    Ann Med 41:480-9. 2009
    ..The large expenditure is an additional source of concern. Finally, a wide-spread population screening also carries several ethical, social, and psychological implications, which might overwhelm the potential benefits...
  15. ncbi request reprint Increased D-dimer value and occult cancer in the absence of detectable thrombosis
    G Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Italy
    Haematologica 92:e53-5. 2007
    ..This case allow us to hypothesize that screening for occult malignancy in the presence of apparently inexplicable elevated D-dimer values may be taken into consideration...
  16. ncbi request reprint Diagnostic value of D-dimer measurement in patients referred to the emergency department with suspected myocardial ischemia
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, 37134 Verona, Italy
    J Thromb Thrombolysis 25:247-50. 2008
    ..The introduction of early and reliable biomarkers of AMI should hence be acknowledged, since they would increase the efficiency of the diagnostic process...
  17. ncbi request reprint Lipid and lipoprotein profile in physiological pregnancy
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita di Verona, Italy
    Clin Lab 53:173-7. 2007
    ....
  18. doi request reprint Unsuspected triggers of venous thromboembolism--trivial or not so trivial?
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospadaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 35:597-604. 2009
    ....
  19. ncbi request reprint Lipoprotein[a] and cancer: anti-neoplastic effect besides its cardiovascular potency
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro 10, 37134 Verona, Italy
    Cancer Treat Rev 33:427-36. 2007
    ..This review is focused on the biochemical structure, metabolism and the anti-angiogenic activity of this unique and elusive kringle-containing lipoprotein...
  20. doi request reprint Biological influence of physical exercise on hemostasis
    Giuseppe Lippi
    Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Italy
    Semin Thromb Hemost 35:269-76. 2009
    ..These adaptive changes might be beneficial in the long term, offering some protection against the risk of thrombosis and adverse cardiovascular events in physically active individuals...
  21. doi request reprint Pharmacogenetics of vitamin K antagonists: useful or hype?
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Biomediche e Morfologiche, Universita di Verona, and Ospedale Policlinico G B Rossi, Verona, Italy
    Clin Chem Lab Med 47:503-15. 2009
    ....
  22. doi request reprint Eosinophilia and first-line coagulation testing
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Biomediche e Morfologiche, Universita di Verona, Ospedale Policlinico G B Rossi, Verona, Italy
    J Thromb Thrombolysis 28:90-3. 2009
    ....
  23. doi request reprint Quality improvement in laboratory medicine: extra-analytical issues
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico GB Rossi, Piazzale Scuro, Verona, Italy
    Clin Lab Med 28:285-94, vii. 2008
    ..The article focuses on appropriateness of the test request, patient and sample identification, criteria for acceptance and rejection of specimens, and the communication and interpretation of results...
  24. ncbi request reprint Influence of a half-marathon run on NT-proBNP and troponin T
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita di Verona, Verona, Italy
    Clin Lab 54:251-4. 2008
    ..In particular, there is still controversy regarding the behaviour of biochemical markers of heart damage and dysfunction following medium term endurance training...
  25. ncbi request reprint Activated partial thromboplastin time: new tricks for an old dogma
    Giuseppe Lippi
    Sezione di Chimica Clinica, Universita di Verona, Verona, Italy
    Semin Thromb Hemost 34:604-11. 2008
    ..In total, such emerging evidence suggests that the APTT is either an old dogma displaying new tricks or else might describe a new dogma for an old laboratory trick...
  26. doi request reprint The paradoxical relationship between serum uric acid and cardiovascular disease
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Biomediche e Morfologiche, Universita di Verona, Italy
    Clin Chim Acta 392:1-7. 2008
    ..The aim of this article is to review uric acid metabolism and physiology, highlighting its association with cardiovascular disease...
  27. doi request reprint Relationship between serum phosphate and cardiovascular risk factors in a large cohort of adult outpatients
    Giuseppe Lippi
    Sezione di Chimica e Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Italy
    Diabetes Res Clin Pract 84:e3-5. 2009
    ....
  28. doi request reprint New strategies for doping control
    Giuseppe Lippi
    Istituto di Chimica e Microscopia Clinica, Universita di Verona, Verona, Italy
    J Sports Sci 26:441-5. 2008
    ..Although this strategy would not detect cheating, it would safeguard athletes' health...
  29. ncbi request reprint Inherited and acquired risk factors for arterial ischemic stroke in childhood
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, 37134 Verona, Italy
    J Thromb Thrombolysis 27:239-48. 2009
    ....
  30. doi request reprint Coagulation testing in pediatric patients: the young are not just miniature adults
    Giuseppe Lippi
    Dipartimento di Scienze Biomediche e Morfologiche, Universita di Verona, Verona, Italy
    Semin Thromb Hemost 33:816-20. 2007
    ....
  31. doi request reprint Milestones and perspectives in coagulation and hemostasis
    Giuseppe Lippi
    Sezione di Chimica Clinica, Universita di Verona, Verona, Italy
    Semin Thromb Hemost 35:9-22. 2009
    ..The aim of this article is to provide a concise overview of the major discoveries and past and current perspectives in coagulation and hemostasis...
  32. doi request reprint Genomics and proteomics in venous thromboembolism: building a bridge toward a rational personalized medicine framework
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Biomediche e Morfologiche, Universita di Verona, Verona, Italy
    Semin Thromb Hemost 33:759-70. 2007
    ..The aim of this review is to provide a concise description of the current and future applications of genomics and proteomics in this challenging pathology...
  33. doi request reprint Laboratory assessment and perioperative management of patients on antiplatelet therapy: from the bench to the bedside
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Biomediche e Morfologiche, Universita di Verona, Italy
    Clin Chim Acta 405:8-16. 2009
    ..The contribution of newer hemostatic agents, such as desmopressin and recombinant activated factor VII, is yet to be fully determined, and there remain many challenges and unresolved issues in the clinical care of these patients...
  34. doi request reprint Updates on improvement of human athletic performance: focus on world records in athletics
    Giuseppe Lippi
    Sezione di Chimica Clinica, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, 37134 Verona, Italy
    Br Med Bull 87:7-15. 2008
    ....
  35. pmc Influence of a light meal on routine haematological tests
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche University of Verona, Ospedale Policlinico G B Rossi, Verona, Italy
    Blood Transfus 8:94-9. 2010
    ..However, no clear indications about fasting requirements exist for routine haematological tests, nor has the influence of meals been assessed...
  36. doi request reprint Influenza and cardiovascular disease: does swine-origin, 2009 H1N1 flu virus represent a risk factor, an acute trigger, or both?
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 36:49-58. 2010
    ....
  37. doi request reprint Thrombotic complications of erythropoiesis-stimulating agents
    Giuseppe Lippi
    U O di Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 36:537-49. 2010
    ....
  38. doi request reprint Laboratory testing in pharmacies
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Chem Lab Med 48:943-53. 2010
    ....
  39. doi request reprint C-reactive protein and venous thromboembolism: causal or casual association?
    Giuseppe Lippi
    U O di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Italy
    Clin Chem Lab Med 48:1693-701. 2010
    ..Although there is increasing emphasis that CRP might not only be a marker but also an active player in the development of venous thrombosis, further evidence is needed to establish which event comes first--thrombosis or inflammation...
  40. ncbi request reprint National survey on the pre-analytical variability in a representative cohort of Italian laboratories
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro 10, 37121 Verona, Italy
    Clin Chem Lab Med 44:1491-4. 2006
    ..The present survey investigated the development of several pre-analytical processes within a representative cohort of Italian clinical laboratories...
  41. doi request reprint Recombinant platelet factor 4: a therapeutic, anti-neoplastic chimera?
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 36:558-69. 2010
    ..These delivery systems aim to produce high concentrations of the therapeutic agent in a local area for a sustained period, thereby avoiding the typical problems encountered with long-term administration of recombinant proteins...
  42. doi request reprint Inflammatory biomarkers for the diagnosis, monitoring and follow-up of community-acquired pneumonia: clinical evidence and perspectives
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Eur J Intern Med 22:460-5. 2011
    ..PCT however carries some additional advantages over CRP, such as the greater specificity for infections and a more narrow range of normal concentrations...
  43. doi request reprint The significance of protein S-100B testing in cardiac arrest patients
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Clin Biochem 44:567-75. 2011
    ....
  44. doi request reprint Moderate red wine consumption and cardiovascular disease risk: beyond the "French paradox"
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 36:59-70. 2010
    ....
  45. doi request reprint Air pollution and coagulation testing: a new source of biological variability?
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, 37134 Verona, Italy
    Thromb Res 123:50-4. 2008
    ....
  46. doi request reprint Direct-to-consumer testing: more risks than opportunities
    G Lippi
    U O Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Int J Clin Pract 65:1221-9. 2011
    ..benefit analyses are needed to definitely establish whether DTC testing might be effective for decreasing the burden of diseases, delay their onset or modify their progression and therefore the clinical outcome...
  47. doi request reprint Effect of hemodialysis on traditional and innovative cardiac markers
    Martina Montagnana
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Verona, Italy
    J Clin Lab Anal 22:59-65. 2008
    ..Moreover, IMA might be reliably applied to stratify the long-term risk of these patients, but not for diagnosing an ACS during or immediately post-HD...
  48. ncbi request reprint Studies on in vitro hemolysis and utility of corrective formulas for reporting results on hemolyzed specimens
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Biochem Med (Zagreb) 21:297-305. 2011
    ..Corrective formulas have been proposed to allow the laboratory to release test results on these specimens. This study aimed to assess the influence of spurious hemolysis and reliability of corrective formulas...
  49. doi request reprint Causes, consequences, detection, and prevention of identification errors in laboratory diagnostics
    Giuseppe Lippi
    University of Verona, Verona, Italy
    Clin Chem Lab Med 47:143-53. 2009
    ..Once misidentification is detected, rejection and recollection is the most suitable approach to manage the specimen...
  50. pmc Foot-strike haemolysis after a 60-km ultramarathon
    Giuseppe Lippi
    Unit of Diagnostic Blood Chemistry, Department of Pathology and Laboratory Medicine, University Hospital of Parma, Parma, Italy
    Blood Transfus 10:377-83. 2012
    ..The effective contribution of foot-strike haemolysis is unclear...
  51. ncbi request reprint Influence of hemolysis on routine clinical chemistry testing
    Giuseppe Lippi
    Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chem Lab Med 44:311-6. 2006
    ..Therefore, the present investigation evaluated the influence of in vitro blood cell lysis on routine clinical chemistry testing...
  52. doi request reprint Procalcitonin values after dialysis is closely related to type of dialysis membrane
    Martina Montagnana
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, Verona 37134, Italy
    Scand J Clin Lab Invest 69:703-7. 2009
    ..In this setting, procalcitonin (PCT) could be useful for detection of systemic bacterial infections...
  53. ncbi request reprint [Role of biochemical risk factors and markers for the risk of atherosclerosis]
    Martina Montagnana
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona
    Recenti Prog Med 99:215-22. 2008
    ..Particularly, biochemical risk factors and markers play a crucial role in all steps of atherosclerosis process, and entail a great relevance in risk stratification and early prevention...
  54. doi request reprint Significant variation of traditional markers of liver injury after a half-marathon run
    Giuseppe Lippi
    U O di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Italy
    Eur J Intern Med 22:e36-8. 2011
    ..As such, this study was undertaken to assess the kinetics of liver injury markers following physical exercise...
  55. ncbi request reprint Biochemistry, physiology, and complications of blood doping: facts and speculation
    Giuseppe Lippi
    Dipartimento di Scienze Morfologico Biomediche, Istituto di Chimica e Microscopia Clinica, Universita degli Studi di Verona, Verona, Italy
    Crit Rev Clin Lab Sci 43:349-91. 2006
    ..The aim of this review is to discuss the biochemistry, physiology, and complications of blood doping and to provide an update on current antidoping policies...
  56. ncbi request reprint Comparison of the lipid profile and lipoprotein(a) between sedentary and highly trained subjects
    Giuseppe Lippi
    Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chem Lab Med 44:322-6. 2006
    ....
  57. ncbi request reprint Biochemical correlates of lipoprotein(a) in a general adult population. Possible implications for cardiovascular risk assessment
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro 10, 37134, Verona, Italy
    J Thromb Thrombolysis 27:44-7. 2009
    ....
  58. doi request reprint Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy
    Martina Montagnana
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro 10, Verona, Italy
    J Clin Lab Anal 23:88-92. 2009
    ..We confirm that the modification of the fine balance between MMPs and their inhibitors plays a greater role in the structural and functional vascular changes of women with complicated pregnancies...
  59. doi request reprint Hemophilia and cancer: a new challenge for hemophilia centers
    Massimo Franchini
    Immunohematology and Transfusion Center Department of Pathology and Laboratory Medicine, University Hospital of Parma, Parma, Italy
    Cancer Treat Rev 35:374-7. 2009
    ..These aspects, along with the epidemiology of cancer in hemophiliacs will be discussed in this review...
  60. doi request reprint Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Arch Pathol Lab Med 133:628-32. 2009
    ..A strong independent association has been recently observed between elevated red blood cell distribution width (RDW) and increased incidence of cardiovascular events...
  61. doi request reprint Increased mean platelet volume in patients with acute coronary syndromes
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Verona, Italy
    Arch Pathol Lab Med 133:1441-3. 2009
    ..Despite remarkable progress, the diagnosis of acute coronary syndromes (ACS) is still challenging...
  62. doi request reprint The ROMA (Risk of Ovarian Malignancy Algorithm) for estimating the risk of epithelial ovarian cancer in women presenting with pelvic mass: is it really useful?
    Martina Montagnana
    Clinical Biochemistry Laboratory, Department of Life and Reproduction Sciences, University Hospital of Verona, Verona, Italy
    Clin Chem Lab Med 49:521-5. 2011
    ....
  63. doi request reprint Obstructive sleep apnea syndrome and cardiovascular diseases
    Cristiano Fava
    Sezione di Medicina interna C, Dipartimento di Scienze Biomediche e Chirurgiche, Universita di Verona, Verona, Italy
    Semin Thromb Hemost 37:280-97. 2011
    ....
  64. pmc Non-commutability of results of highly sensitive troponin I and T immunoassays
    Giuseppe Lippi
    U O di Diagnostica Ematochimica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Biochem Med (Zagreb) 22:127-9. 2012
    ..However, no information is available on the commutability of results between the novel highly-sensitive (HS) troponin T (TnT) and I (TnI) immunoassays...
  65. ncbi request reprint Evaluation of cardiac involvement following major orthopedic surgery
    Martina Montagnana
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chem Lab Med 44:1340-6. 2006
    ....
  66. ncbi request reprint Multicenter evaluation of the hemolysis index in automated clinical chemistry systems
    Giuseppe Lippi
    Clinical Chemistry Laboratory, University of Verona, Verona, Italy
    Clin Chem Lab Med 47:934-9. 2009
    ....
  67. doi request reprint Extracorporeal immunoadsorption for the treatment of coagulation inhibitors
    Massimo Franchini
    Immunohematology and Transfusion Center, University Hospital of Parma, Parma, Italy
    Semin Thromb Hemost 35:76-80. 2009
    ..However, further randomized clinical trials are needed to better assess the cost-effectiveness of such procedures...
  68. doi request reprint Relationship of serum gamma-glutamyltransferase to atherogenic dyslipidemia and glycemic control in type 2 diabetes
    Giacomo Zoppini
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University Hospital of Verona, Verona, Italy
    Obesity (Silver Spring) 17:370-4. 2009
    ..These findings suggest that obesity itself may not be a sufficient risk factor for atherogenic dyslipidemia or poor glycemic control in people with type 2 diabetes...
  69. ncbi request reprint Influence of warfarin therapy on activated factor VII clotting activity
    Giuseppe Lippi
    Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Blood Coagul Fibrinolysis 17:221-4. 2006
    ..Owing to the good correlation with FVIIa:C, we also hypothesize that the PT and/or FVII:C might be employed for monitoring recombinant FVIIa therapy...
  70. doi request reprint Epidemiological association between uric acid concentration in plasma, lipoprotein(a), and the traditional lipid profile
    Giuseppe Lippi
    Section of Clinical Chemistry, University of Verona Medical School, Verona, Italy
    Clin Cardiol 33:E76-80. 2010
    ..It is unclear whether they are independent risk factors or simply markers, reflecting association with other traditional risk factors...
  71. ncbi request reprint Relationship between red blood cell distribution width and kidney function tests in a large cohort of unselected outpatients
    Giuseppe Lippi
    Dipartimento di Scienze Morfologico Biomediche, Sezione di Chimica Clinica, Universita degli Studi di Verona, Verona, Italy
    Scand J Clin Lab Invest 68:745-8. 2008
    ..However, the mechanism(s) underlying this association remains unclear. Since impaired kidney function is a well-known risk factor for cardiovascular disease, we assessed whether RDW is associated with decreased kidney function...
  72. ncbi request reprint Evaluation of cardiac laboratory markers in patients with systemic sclerosis
    Martina Montagnana
    Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Verona, Italy
    Clin Biochem 39:913-7. 2006
    ..The aim of this study was the evaluation of the early subclinical cardiac involvement in patients with systemic sclerosis by means of non-invasive laboratory cardiac markers...
  73. doi request reprint Prophylaxis in congenital hemophilia with inhibitors: the role of recombinant activated factor VII
    Massimo Franchini
    Servizio di Immunoematologia e Medicina Trasfusionale, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Parma, Italy
    Semin Thromb Hemost 35:814-9. 2009
    ..The published data on the use of rFVIIa as a prophylactic treatment in hemophilia patients with inhibitors are reviewed in this article...
  74. ncbi request reprint High prevalence of inherited prothrombotic risk factors in 134 consecutive patients with von Willebrand disease
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione, Azienda Ospedaliera di Verona, Verona, Italy
    Am J Hematol 81:465-7. 2006
    ..Three carriers of multiple prothrombotic gene mutations experienced a thrombotic event. Our study suggests that the recent evidence of an association between inherited thrombotic and hemorrhagic disorders also holds true in VWD patients...
  75. ncbi request reprint Cardiac troponins and physical exercise. It's time to make a point
    Giuseppe Lippi
    U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero Universitaria di Parma, Italy
    Biochem Med (Zagreb) 21:55-62. 2011
    ..e., serial measurement of cardiac biomarkers, detailed clinical history-taking, integration with ECG and imaging findings) to prevent misdiagnosis of ACS and/or MI in otherwise healthy persons...
  76. ncbi request reprint National survey on critical values reporting in a cohort of Italian laboratories
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chem Lab Med 45:1411-3. 2007
    ..Critical values' reporting is an essential requisite for clinical laboratories. Local policies were investigated within an indicative cohort of Italian laboratories to monitor the situation and establish a performance benchmark...
  77. ncbi request reprint Prevalence and type of preanalytical errors on inpatient samples referred for complete blood count
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Verona, Italy
    Clin Lab 53:555-6. 2007
  78. ncbi request reprint Relationship between matrix metalloproteinases/tissue inhibitors of matrix metalloproteinases systems and autoantibody patterns in systemic sclerosis
    Martina Montagnana
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, Verona, Italy
    Clin Biochem 40:837-42. 2007
    ..This activity is controlled by tissue inhibitors of MMP (TIMPs). Aim of this study was the evaluation of MMP-9/TIMP-1 and MMP-2/TIMP-2 systems in patients with SSc...
  79. ncbi request reprint Routine coagulation tests in newborn and young infants
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Ospedale Policlinico G B Rossi, Universita degli Studi di Verona, Piazzale Scuro, 10, 37134 Verona, Italy
    J Thromb Thrombolysis 24:153-5. 2007
    ..The diagnostic approach to haemostatic defects in the newborn is challenging and requires appropriate interpretation of coagulation tests according to reference values dependent on the postnatal age...
  80. pmc Determinants of anaemia in the very elderly: a major contribution from impaired renal function?
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona
    Blood Transfus 8:44-8. 2010
    ..The frequency of nutritional anaemias is particularly uncertain, since there is controversy on the real prevalence of folate, vitamin B12 and iron deficiencies, as well as on their potential pathophysiological relationship with anaemia...
  81. ncbi request reprint Effect of specimen collection on routine coagulation assays and D-dimer measurement
    Giuseppe Lippi
    Istituto di Chimica Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chem 50:2150-2. 2004
  82. doi request reprint Circadian variation within hemostasis: an underrecognized link between biology and disease?
    Martina Montagnana
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Semin Thromb Hemost 35:23-33. 2009
    ..In this review, clinical and laboratory data describing the effects of these cyclical rhythms on the hemostatic system are discussed...
  83. doi request reprint The bidirectional relationship of cancer and hemostasis and the potential role of anticoagulant therapy in moderating thrombosis and cancer spread
    Massimo Franchini
    Immunohematology and Transfusion Center, Department of Pathology and Laboratory Medicine, University Hospital of Parma, Parma, Italy
    Semin Thromb Hemost 35:644-53. 2009
    ..The main biological and clinical evidence on the relationship between cancer and hemostasis are briefly summarized in this review, as is the potential benefits of anticoagulant therapy in this setting...
  84. doi request reprint The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure
    Cristiano Fava
    Department of Biomedical and Surgical Sciences, Division of Internal Medicine C, Piazza LA Scuro 10, 37134 Verona, Italy
    Hypertension 52:373-80. 2008
    ..A common CYP4F2 V433M polymorphism might increase the risk of incident ischemic stroke in male subjects only partially through its elevating effect on BP. Additional studies are needed to confirm these data...
  85. ncbi request reprint Lipoprotein[a] and the lipid profile in patients with systemic sclerosis
    Giuseppe Lippi
    Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Ospedale Policlinico G B Rossi, Piazzale Scuro, 10, 37134 Verona, Italy
    Clin Chim Acta 364:345-8. 2006
    ..Little is known so far on the lipid profile of these patients...
  86. ncbi request reprint The use of recombinant activated factor VII in congenital and acquired von Willebrand disease
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy
    Blood Coagul Fibrinolysis 17:615-9. 2006
    ..Further studies are needed, however, to assess its safety and to optimize the dosages and regimens of therapy in such patients...
  87. doi request reprint Will "personalized medicine" need personalized laboratory approach?
    Gian Cesare Guidi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Italy
    Clin Chim Acta 400:25-9. 2009
    ..Great emphasis is currently presently placed on personalized medicine, particularly by many of the most influential healthcare-linked institutions, communities, organisations and companies...
  88. ncbi request reprint Rituximab for the treatment of childhood chronic idiopathic thrombocytopenic purpura and hemophilia with inhibitors
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy
    Pediatr Blood Cancer 49:6-10. 2007
    ..Therefore, large, prospective, and randomized trials are needed to confirm the positive, preliminary results...
  89. ncbi request reprint Managing transferability of laboratory data
    Gian Cesare Guidi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chim Acta 374:57-62. 2006
    ....
  90. doi request reprint NASH predicts plasma inflammatory biomarkers independently of visceral fat in men
    Giovanni Targher
    Department of Internal Medicine, Sacro Cuore Hospital, Negrar VR, Italy
    Obesity (Silver Spring) 16:1394-9. 2008
    ..In conclusion, our results suggest that NASH can predict a more atherogenic risk profile in a manner that is partly independent from the contribution of visceral adiposity in adult men...
  91. ncbi request reprint Potential role of recombinant activated factor VII for the treatment of severe bleeding associated with disseminated intravascular coagulation: a systematic review
    Massimo Franchini
    Immunohematology and Transfusion Center, City Hospital of Verona, Italy
    Blood Coagul Fibrinolysis 18:589-93. 2007
    ..Large randomized trials are needed, however, to confirm the preliminary results and to assess the safety and dosing regimens of this agent in refractory bleeding associated with disseminated intravascular coagulation...
  92. ncbi request reprint Drug-induced anti-factor VIII antibodies: a systematic review
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy
    Med Sci Monit 13:RA55-61. 2007
    ..3%). However, further studies are needed to better elucidate the epidemiology, natural history, clinical relevance, and optimal treatment of drug-associated factor VIII autoantibodies...
  93. ncbi request reprint Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients
    Giovanni Targher
    Unit of Internal Medicine and Diabetes, Sacro Cuore Hospital of Negrar, Negrar, Italy
    Diabetes Care 30:2119-21. 2007
  94. ncbi request reprint Von Willebrand factor and thrombosis
    Massimo Franchini
    Servizio di Immunoematologia e Trasfusione, Ospedale Policlinico, Azienda Ospedaliera di Verona, Piazzale L Scuro, 10, 37134, Verona, Italy
    Ann Hematol 85:415-23. 2006
    ..After a description of the structure and physiology of VWF, all these aspects are discussed in the present review...
  95. ncbi request reprint Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-treated retinopathy in type 2 diabetic patients
    G Targher
    Department of Internal Medicine, Sacro Cuore Hospital, Negrar VR, Italy
    Diabetologia 51:444-50. 2008
    ..We assessed the associations between NAFLD and both chronic kidney disease (CKD) and retinopathy in a large cohort of type 2 diabetic individuals using a cross-sectional design...
  96. doi request reprint Clinical, laboratory and therapeutic aspects of platelet-type von Willebrand disease
    M Franchini
    Servizio di Immunoematologia e Trasfusione, Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy
    Int J Lab Hematol 30:91-4. 2008
    ..In this review, the main clinical, laboratory and therapeutic characteristics of PT-VWD are concisely reported...
  97. doi request reprint Diabetic retinopathy is associated with an increased incidence of cardiovascular events in Type 2 diabetic patients
    G Targher
    Division of Internal Medicine, Sacro Cuore Hospital of Negrar VR, Verona, Italy
    Diabet Med 25:45-50. 2008
    ..We investigated the association of diabetic retinopathy with the risk of incident cardiovascular disease (CVD) events in a large cohort of Type 2 diabetic adults...
  98. ncbi request reprint Influence of temperature and time before centrifugation of specimens for routine coagulation testing
    G L Salvagno
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Int J Lab Hematol 31:462-7. 2009
    ..In conclusion, a 6-h storage of uncentrifuged specimens at either RT or 4 degrees C may still be suitable to achieve results of routine coagulation testing comprised within the analytical quality specifications for desirable bias...
  99. ncbi request reprint Relationship between soluble CD40 ligand and gamma-glutamyltransferase concentrations in non-drinking, young Type 1 diabetic individuals
    G Zoppini
    Department of Biomedical and Surgical Sciences, Section of Clinical Chemistry, Section of Endocrinology, University of Verona, Verona, Italy
    Diabet Med 25:1283-8. 2008
    ..To assess the association between circulating levels of soluble CD40 ligand (sCD40L), an emerging cardiovascular risk factor, and gamma-glutamyltransferase (GGT) activity concentrations in Type 1 diabetic subjects...
  100. ncbi request reprint Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and retinopathy in type 1 diabetic patients
    G Targher
    Section of Endocrinology and Metabolism, Department of Biomedical and Surgical Sciences, University of Verona, Ospedale Civile Maggiore, Piazzale Stefani 1, 37126, Verona, Italy
    Diabetologia 53:1341-8. 2010
    ..Information on this issue is lacking for type 1 diabetes. We evaluated whether NAFLD is associated with increased prevalence of retinopathy and CKD in type 1 diabetic patients...
  101. ncbi request reprint The potential role of recombinant activated FVII in the management of critical hemato-oncological bleeding: a systematic review
    M Franchini
    1Servizio di Immunoematologia e Trasfusione Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy
    Bone Marrow Transplant 39:729-35. 2007
    ..Thus, further trials with larger numbers of patients are needed to establish the most appropriate doses and timing of rFVIIa and to assess its efficacy and safety in this setting...