A Lenzi

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. ncbi request reprint Type V phosphodiesterase inhibitor treatments for erectile dysfunction increase testosterone levels
    Eleonora Carosa
    Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
    Clin Endocrinol (Oxf) 61:382-6. 2004
  2. ncbi request reprint The andrologist from medicine of reproduction to sexual medicine: the Italian experience
    A Lenzi
    Chair of Endocrinology, Department of Medical Physiopathology, University of Rome La Sapienza, Policlinico Umberto I, 00161 Rome, Italy
    Int J Androl 28:9-13. 2005
  3. ncbi request reprint Testosterone replacement therapy: what we know is not yet enough
    Andrea M Isidori
    Mayo Clin Proc 82:11-3. 2007
  4. ncbi request reprint Androgens improve cavernous vasodilation and response to sildenafil in patients with erectile dysfunction
    Antonio Aversa
    AFaR CRCCS, Ospedale Fatebenefratelli Isola Tiberina, Rome, Italy
    Clin Endocrinol (Oxf) 58:632-8. 2003
  5. ncbi request reprint Stress, sexual dysfunctions, and male infertility
    A Lenzi
    Department of Medical Physiopathology, 1st University of Rome La Sapienza, Rome, Italy
    J Endocrinol Invest 26:72-6. 2003
  6. pmc Towards the eradication of HPV infection through universal specific vaccination
    Piergiorgio Crosignani
    Fondazione Giovanni Lorenzini Medical Science Foundation, Milan, Italy
    BMC Public Health 13:642. 2013
  7. pmc Rome Consensus Conference - statement; human papilloma virus diseases in males
    Andrea Lenzi
    Institute Department of Endocrinology, La Sapienza University, Rome, Italy
    BMC Public Health 13:117. 2013
  8. ncbi request reprint The role of the medical andrologist in the assisted reproduction era
    A Lenzi
    Chair of Clinical Pathology, Department of Medical Pathophysiology, Unit of Seminology, Reproductive Immunology, Section of Rome Training Centre in Andrology, European Academy of Andrology, University of Rome La Sapienza, Italy
    J Endocrinol Invest 26:268-73. 2003
  9. ncbi request reprint A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia
    Andrea Lenzi
    Department of Medical Physiopathology, University of Rome La Sapienza, Rome, Italy
    Fertil Steril 81:1578-84. 2004
  10. pmc The role of antioxidant therapy in the treatment of male infertility: an overview
    Francesco Lombardo
    Department of Experimental Medicine, Policlinico Umberto I, University of Rome La Sapienza, Rome 00161, Italy
    Asian J Androl 13:690-7. 2011

Detail Information

Publications100

  1. ncbi request reprint Type V phosphodiesterase inhibitor treatments for erectile dysfunction increase testosterone levels
    Eleonora Carosa
    Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
    Clin Endocrinol (Oxf) 61:382-6. 2004
    ..In this paper we studied the effect of different type V phosphodiesterase (PDE5) inhibitor treatments for ED on the reversibility of this endocrine pattern...
  2. ncbi request reprint The andrologist from medicine of reproduction to sexual medicine: the Italian experience
    A Lenzi
    Chair of Endocrinology, Department of Medical Physiopathology, University of Rome La Sapienza, Policlinico Umberto I, 00161 Rome, Italy
    Int J Androl 28:9-13. 2005
    ....
  3. ncbi request reprint Testosterone replacement therapy: what we know is not yet enough
    Andrea M Isidori
    Mayo Clin Proc 82:11-3. 2007
  4. ncbi request reprint Androgens improve cavernous vasodilation and response to sildenafil in patients with erectile dysfunction
    Antonio Aversa
    AFaR CRCCS, Ospedale Fatebenefratelli Isola Tiberina, Rome, Italy
    Clin Endocrinol (Oxf) 58:632-8. 2003
    ..This led us to further investigate the effect(s) of androgen administration on cavernous arteries in patients failing sildenafil treatment...
  5. ncbi request reprint Stress, sexual dysfunctions, and male infertility
    A Lenzi
    Department of Medical Physiopathology, 1st University of Rome La Sapienza, Rome, Italy
    J Endocrinol Invest 26:72-6. 2003
    ....
  6. pmc Towards the eradication of HPV infection through universal specific vaccination
    Piergiorgio Crosignani
    Fondazione Giovanni Lorenzini Medical Science Foundation, Milan, Italy
    BMC Public Health 13:642. 2013
    ..Moreover, no screening procedures for HPV-related disease prevention are applied in men, who fail to undergo routine medical testing by any medical specialist at all. They also do not benefit from government prevention strategies...
  7. pmc Rome Consensus Conference - statement; human papilloma virus diseases in males
    Andrea Lenzi
    Institute Department of Endocrinology, La Sapienza University, Rome, Italy
    BMC Public Health 13:117. 2013
    ..The objective of the Consensus Conference was to make evidence-based recommendations that were designed to facilitate the adoption of a standard approach in clinical practice in Italy...
  8. ncbi request reprint The role of the medical andrologist in the assisted reproduction era
    A Lenzi
    Chair of Clinical Pathology, Department of Medical Pathophysiology, Unit of Seminology, Reproductive Immunology, Section of Rome Training Centre in Andrology, European Academy of Andrology, University of Rome La Sapienza, Italy
    J Endocrinol Invest 26:268-73. 2003
  9. ncbi request reprint A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia
    Andrea Lenzi
    Department of Medical Physiopathology, University of Rome La Sapienza, Rome, Italy
    Fertil Steril 81:1578-84. 2004
    ..To determine the efficacy of combined l-carnitine and l-acetyl-carnitine therapy in infertile males with oligo-astheno-teratozoospermia...
  10. pmc The role of antioxidant therapy in the treatment of male infertility: an overview
    Francesco Lombardo
    Department of Experimental Medicine, Policlinico Umberto I, University of Rome La Sapienza, Rome 00161, Italy
    Asian J Androl 13:690-7. 2011
    ....
  11. ncbi request reprint Use of carnitine therapy in selected cases of male factor infertility: a double-blind crossover trial
    Andrea Lenzi
    Outpatient Department and Laboratory of Seminology and Reproductive Immunology at the Training Center in Andrology of the European Academy of Andrology, Rome, Italy
    Fertil Steril 79:292-300. 2003
    ..To determine the efficacy of L-carnitine therapy in selected cases of male factor infertility...
  12. doi request reprint A pilot study to evaluate the effects of vardenafil on sexual distress in men with obesity
    A Aversa
    Department Experimental Medicine, Medical Physiopathology, Food Science and Endocrinology Section, Sapienza University of Rome, Rome, Italy
    Int J Impot Res 24:122-5. 2012
    ..Our preliminary results suggest that treatment with VAR may improve ejaculatory control, thus ameliorating self-esteem and sexual performance in men with obesity...
  13. ncbi request reprint Lipoperoxidation damage of spermatozoa polyunsaturated fatty acids (PUFA): scavenger mechanisms and possible scavenger therapies
    A Lenzi
    Department of Medical Physiopathology, Laboratory of Seminology and Immunology of Reproduction, University of Rome La Sapienza, Rome, Italy
    Front Biosci 5:E1-E15. 2000
    ..Scavengers, such as GSH, can be used to treat these cases as they can restore the physiological constitution of PUFA in the cell membrane. The results of GSH therapy are presented and discussed...
  14. ncbi request reprint The long-acting phosphodiesterase inhibitor tadalafil does not influence athletes' VO2max, aerobic, and anaerobic thresholds in normoxia
    L Di Luigi
    Department of Health Sciences, University of Rome IUSM, Rome, Italy
    Int J Sports Med 29:110-5. 2008
    ....
  15. ncbi request reprint Might erectile dysfunction be due to the thermolabile variant of methylenetetrahydrofolate reductase?
    F Lombardo
    Unit of Seminology and Immunology of Reproduction, Department of Medical Physiopathology, University of Rome La Sapienza, Rome, Italy
    J Endocrinol Invest 27:883-5. 2004
    ..Furthermore, careful attention should be given to the risk of ED when dealing with this metabolic disturbance...
  16. ncbi request reprint Control and impairment of immune privilege in the testis and in semen
    A Filippini
    Department of Histology and Medical Embryology, University of Rome La Sapienza, Italy
    Hum Reprod Update 7:444-9. 2001
    ....
  17. ncbi request reprint Hormone and genetic study in male to female transsexual patients
    F Lombardo
    Department of Experimental Medicine, Policlinico Umberto I, University of Rome La Sapienza, Viale del Policlinico 155, 00161, Rome, Italy
    J Endocrinol Invest 36:550-7. 2013
    ..Data of the literature demonstrated controversial results of a correlation between transsexualism and genetic mutations...
  18. ncbi request reprint A multicenter evaluation of immunoassays for follicle-stimulating hormone, luteinizing hormone and testosterone: concordance, imprecision and reference values
    A Radicioni
    Department of Medical Pathophysiolgy, Sapienza University of Rome, Rome, Italy
    J Endocrinol Invest 36:739-44. 2013
    ..A comparison of assay methods is thus an important starting point for the achievement of universally accepted reference values...
  19. ncbi request reprint Androgens and fertility
    F Lombardo
    Department of Medical Pathophysiology, 1st University of Rome La Sapienza, Rome, Italy
    J Endocrinol Invest 28:51-5. 2005
    ..Abuse of anabolic steroids is a frequent cause of male infertility, and substances such as endocrine disruptors can alter male fertility through an anti androgenic action...
  20. ncbi request reprint Presence of membrane and soluble forms of Fas ligand and of matrilysin (MMP-7) activity in normal and abnormal human semen
    A Riccioli
    Department of Histology and Medical Embryology, Istituto Pasteur Fondazione Cenci Bolognetti, University of Rome La Sapienza, Italy
    Hum Reprod 20:2814-20. 2005
    ....
  21. ncbi request reprint Cryopreservation and sperm DNA integrity
    L Gandini
    Laboratory of Seminology and Reproductive Immunology, Department of Medical Pathophysiology, University of Rome La Sapienza, 00100, Rome, Italy
    Cell Tissue Bank 7:91-8. 2006
    ..Overall sperm quality was found to deteriorate after cryopreservation. When thawed spermatozoa were subjected to an extra swim-up round, a general improvement in nuclear maturity was seen in post-rise spermatozoa...
  22. doi request reprint Protamine-1 and -2 polymorphisms and gene expression in male infertility: an Italian study
    D Grassetti
    Department of Experimental Medicine, University of Rome La Sapienza, Viale del Policlinico 155, 00161 Rome, Italy
    J Endocrinol Invest 35:882-8. 2012
    ..There are two types of protamines: protamine 1 (P1) and the protamine 2 family (P2, P3, and P4), coded by the genes PRM1 and PRM2...
  23. doi request reprint Multiple forms of hypogonadism of central, peripheral or combined origin in males with Prader-Willi syndrome
    A F Radicioni
    Department of Experimental Medicine, Sapienza University of Rome, Italy
    Clin Endocrinol (Oxf) 76:72-7. 2012
    ..Hypogonadism in Prader-Willi syndrome (PWS) is generally attributed to hypothalamic dysfunction or to primary gonadal defect, but pathophysiology is still unclear...
  24. ncbi request reprint Diagnosing erectile dysfunction: instruments for endocrine diagnosis
    F Lombardo
    Department of Medical Pathophysiology, Laboratory of Seminology and Immunology of Reproduction, Policlinico Umberto I, 1st University of Rome La Sapienza, Rome, Italy
    Int J Androl 28:53-5. 2005
    ....
  25. ncbi request reprint Psychosocial issues of ART in aging male
    E Carosa
    Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
    J Endocrinol Invest 28:117-21. 2005
    ....
  26. doi request reprint Efficacy and safety of two different testosterone undecanoate formulations in hypogonadal men with metabolic syndrome
    A Aversa
    Department of Experimental Medicine, Sapienza University of Rome, Viale Policlinico 155, Rome, Italy
    J Endocrinol Invest 33:776-83. 2010
    ..To investigate efficacy and safety of two different preparations of testosterone undecanoate (TU) in 52 hypogonadal men [mean age 57 yr and mean testosterone (T) < 320 ng/dl] with metabolic syndrome (MS)...
  27. doi request reprint Strategies and advantages of early diagnosis in Klinefelter's syndrome
    A F Radicioni
    Department of Medical Pathophysiology, Sapienza University of Rome, Rome, Italy
    Mol Hum Reprod 16:434-40. 2010
    ..To achieve this, it is crucial to increase both medical and general awareness of the disease, including through use of the media and patients' associations...
  28. doi request reprint Is there a role for phosphodiesterase type-5 inhibitors in the treatment of premature ejaculation?
    A Aversa
    Department of Medical Pathophysiology, Sapienza University of Rome, Rome, Italy
    Int J Impot Res 23:17-23. 2011
    ..The aim of this review is to discuss basic rationale and to show clinical evidence sustaining the possibility to use off-label PDE5-i's to treat PE...
  29. ncbi request reprint Consensus statement on diagnosis and clinical management of Klinefelter syndrome
    A F Radicioni
    Rare Diseases Regional Centre, Department of Medical Pathophysiology, Sapienza University of Rome, Viale del Policlinico 155, Rome, Italy
    J Endocrinol Invest 33:839-50. 2010
    ..The workshop was carried out under the auspices of the Italian Society of andrology and Sexual Medicine (SIAMS)...
  30. doi request reprint Testosterone responses to standardized short-term sub-maximal and maximal endurance exercises: issues on the dynamic adaptive role of the hypothalamic-pituitary-testicular axis
    P Sgro
    Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy
    J Endocrinol Invest 37:13-24. 2014
    ..Few and conflicting data on the acute adaptive role of the hypothalamic-pituitary-testicular (HPT) axis to sub-maximal endurance exercise exist...
  31. doi request reprint Reference ranges for thyroid hormones in normal Italian children and adolescents and overweight adolescents
    A F Radicioni
    Section of Medical Pathophysiology and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy
    J Endocrinol Invest 36:326-30. 2013
    ..As thyroid hormones are essential for normal pubertal growth and sexual development, TSH, free T₃ (FT₃) and free T₄ (FT₄) levels undergo progressive modification during childhood and puberty...
  32. ncbi request reprint HIV-1 viral DNA is present in ejaculated abnormal spermatozoa of seropositive subjects
    B Muciaccia
    Department of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy
    Hum Reprod 22:2868-78. 2007
    ..However, the presence of HIV-1 in spermatozoa has been a matter of debate, since the sperm cell fraction may contain somatic infected cells that jeopardize the attribution of the detected virus to the spermatozoa...
  33. doi request reprint Urinary and serum hormones profiles after testosterone enanthate administration in male hypogonadism: concerns on the detection of doping with testosterone in treated hypogonadal athletes
    L Di Luigi
    Unit of Endocrinology, Department of Health Sciences, University of Rome Foro Italico, Rome, Italy
    J Endocrinol Invest 32:445-53. 2009
    ....
  34. doi request reprint Epidemiology, diagnosis, and treatment of male hypogonadotropic hypogonadism
    A Lenzi
    Department of Medical Physiopathology, University of Rome La Sapienza, Rome, Italy
    J Endocrinol Invest 32:934-8. 2009
    ..This commentary aims at reviewing knowledge on the forms of male HH in order to indicate and discuss clinical context, diagnostic and therapeutic approach in the less known non-classical form, i.e. FHH...
  35. ncbi request reprint Testosterone treatment to mimic hormone physiology in androgen replacement therapy. A view on testosterone gel and other preparations available
    Andrea Fabbri
    Universita Tor Vergata, Cattedra di Endocrinologia, UOC Endocrinologia, Ospedale S Eugenio, Rome, Italy
    Expert Opin Biol Ther 7:1093-106. 2007
    ....
  36. ncbi request reprint Correlation between ejaculatory and erectile dysfunction
    E A Jannini
    Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, Coppito, Bldg 2, Room A2 54 Via Vetoio, 67100 L Aquila, Rome, Italy
    Int J Androl 28:40-5. 2005
    ..Finally, erectile dysfunctions (ED) and ejaculatory dysfunctions frequently overlap. The aim of this review article is to propose a new taxonomy of PE, which considers ED as an important factor of PE and vice versa...
  37. doi request reprint Effects of a dietary supplement on chronic pelvic pain syndrome (Category IIIA), leucocytospermia and semen parameters
    F Lombardo
    Department of Experimental Medicine, Policlinico Umberto I, University of Rome La Sapienza, Rome, Italy
    Andrologia 44:672-8. 2012
    ..Improvements were also seen in the pain score of the NIH-Chronic Prostatitis Symptom Index (CPSI), confirming that the reduced inflammation also resulted in a reduction in pain...
  38. doi request reprint Subclinical hyperthyroidism and sport eligibility: an exploratory study on cardiovascular pre-participation screening in subjects treated with levothyroxine for multinodular goiter
    L Di Luigi
    Unit of Endocrinology, Department of Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy
    J Endocrinol Invest 32:825-31. 2009
    ..Subclinical hyperthyroidism (sHT) affects cardiovascular (CV) morphology and function; whether such changes can impact on sport eligibility is unclear...
  39. doi request reprint Semen quality in men with Y chromosome aberrations
    A Antonelli
    Department of Cellular Biotechnology and Haematology, University of Rome La Sapienza, Rome, Italy
    Int J Androl 34:453-60. 2011
    ..The failure of meiosis and, in consequence, spermatogenesis may be a result of the failure to inactivate the X chromosome in the meiotic prophase, which is necessary for normal male spermatogenesis to take place...
  40. ncbi request reprint Testicular function in boys previously treated with recombinant-human growth hormone for non-growth hormone-deficient short stature
    A F Radicioni
    Chair of Endocrinology, Department of Medical Pathophysiology, 1st University of Rome La Sapienza, Rome, Italy
    J Endocrinol Invest 30:931-6. 2007
    ..This study suggests that recombinant hGH treatment has no detrimental effects on the development and maturation of male gonadal function in non- GH deficient short stature young patients...
  41. ncbi request reprint Antisperm immunity in natural and assisted reproduction
    F Lombardo
    Department of Medical Physiopathology, University of Rome La Sapienza, Italy
    Hum Reprod Update 7:450-6. 2001
    ..ASA evaluation in all couples who undergo the various techniques of insemination or IVF is imperative...
  42. doi request reprint Effects of a dietary supplement on cholesterol in subjects with moderate hypercholesterolemia
    F Lombardo
    Department of Experimental Medicine, Policlinico Umberto I, University Sapienza, Rome, Italy
    Clin Ter 164:e147-50. 2013
    ....
  43. ncbi request reprint Risk factors for androgen decline in older males: lifestyle, chronic diseases and drugs
    A M Isidori
    Department of Medical Physiopathology, La Sapienza University, Rome, Italy
    J Endocrinol Invest 28:14-22. 2005
    ..These issues are reviewed in a clinical perspective...
  44. ncbi request reprint Endocrinological diagnosis in sexology
    F Lombardo
    University Laboratory of Seminology and Immunology of Reproduction, Department of Medical Pathophysiology, 1st University of Rome La Sapienza, Rome, Italy
    J Endocrinol Invest 26:112-4. 2003
    ..It is therefore necessary that the diagnostic process for sexual dysfunctions of an endocrine nature be as integrated and wide as possible, especially as such pathologies are usually extremely responsive to medical or surgical therapy...
  45. ncbi request reprint Are subjects with erectile dysfunction aware of their condition? Results from a retrospective study based on an Italian free-call information service
    A Aversa
    Department of Medical Pathophysiology, University La Sapienza, Rome, Italy
    J Endocrinol Invest 27:548-56. 2004
    ..Effective prevention of ED commences with better awareness of the pathological causes by the population and modification of risk factors by the doctors...
  46. ncbi request reprint Polyunsaturated fatty acids of germ cell membranes, glutathione and blutathione-dependent enzyme-PHGPx: from basic to clinic
    A Lenzi
    Laboratory of Seminology and Immunology of Human Reproduction, Department of Medical Pathophysiology, University of Rome La Sapienza, Italy
    Contraception 65:301-4. 2002
    ..Scavengers, such as glutathione can be used to treat these cases as they can restore the physiological constitution of PUFA in the cell membrane...
  47. ncbi request reprint Changes in serum inhibin B during normal male puberty
    A F Radicioni
    Clinical Pathology, Department of Medical Pathophysiology, University of Rome, La Sapienza, Italy
    Eur J Endocrinol 152:403-9. 2005
    ..The aims of this study were to evaluate the changes of InhB during puberty in the male and the relationship between InhB and FSH, LH, testosterone and testicular volume...
  48. doi request reprint Wrist circumference is a clinical marker of insulin resistance in overweight and obese children and adolescents
    Marco Capizzi
    Department of Clinical Sciences, Sapienza University of Rome, Polo Pontino, Viale del Policlinico 155, Rome, Italy
    Circulation 123:1757-62. 2011
    ..The aim of the current study was to find an easy-to-detect clinical marker of insulin resistance which can be used to identify young subjects at increased risk of cardiovascular disease...
  49. ncbi request reprint Ectopic ACTH syndrome
    Andrea M Isidori
    Department of Pathophysiology, Sapienza University of Rome, Italy
    Arq Bras Endocrinol Metabol 51:1217-25. 2007
    ..Their prevalence and the best localization modalities are presented. Medical and surgical management is discussed on the basis of the extensive experience of major referral centres...
  50. ncbi request reprint Effects of testosterone on body composition, bone metabolism and serum lipid profile in middle-aged men: a meta-analysis
    Andrea M Isidori
    Cattedra di Andrologia, Universita La Sapienza, Rome, Italy
    Clin Endocrinol (Oxf) 63:280-93. 2005
    ....
  51. doi request reprint Effects of testosterone undecanoate on cardiovascular risk factors and atherosclerosis in middle-aged men with late-onset hypogonadism and metabolic syndrome: results from a 24-month, randomized, double-blind, placebo-controlled study
    Antonio Aversa
    Department of Medical Pathophysiology, Sapienza University of Rome, Italy
    J Sex Med 7:3495-503. 2010
    ..Longitudinal studies have demonstrated that male hypogonadism could be considered a surrogate marker of incident cardiovascular disease...
  52. ncbi request reprint Erectile dysfunction in aging male
    Francesco Romanelli
    Department of Medical Pathophysiology, Sapienza University of Rome, Italy
    Acta Biomed 81:89-94. 2010
    ..These therapies are effective in the elderly, with no increase in the frequency of adverse events, and might also help in providing relief from lower urinary tract symptoms...
  53. ncbi request reprint Sperm tail agenesis in a case of consanguinity
    Maurizio Latini
    Department of Medical Pysiopathology, University of Rome La Sapienza, Rome, Italy
    Fertil Steril 81:1688-91. 2004
    ..To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity...
  54. ncbi request reprint Effects of testosterone on sexual function in men: results of a meta-analysis
    Andrea M Isidori
    Cattedra di Andrologia, Universita La Sapienza, Rome, Italy
    Clin Endocrinol (Oxf) 63:381-94. 2005
    ..The aim of this study was to assess and compare the effects of T on the different domains of sexual life...
  55. doi request reprint Treatment of erectile dysfunction due to C677T mutation of the MTHFR gene with vitamin B6 and folic acid in patients non responders to PDE5i
    Francesco Lombardo
    Department of Medical Pathophysiology, University of Rome La Sapienza, Rome, Italy
    J Sex Med 7:216-23. 2010
    ..Since hyperhomocysteinemia is considered an important cardiovascular risk factor, it could also be involved in the pathogenesis of ED...
  56. ncbi request reprint Clinical and laboratoristic strategy in late onset hypogonadism
    Francesco Lombardo
    Dipartimento di Fisiopatologia Medica, Universitt di Roma Sapienza
    Acta Biomed 81:85-8. 2010
    ..The exact target testosterone level is a matter of debate, but current recommendations advocate levels in the mid-lower normal adult range...
  57. doi request reprint The challenge of reform: 10 years of curricula change in Italian medical schools
    Huon Snelgrove
    First and Second Faculty of Medicine, Sapienza University of Rome, Rome, Italy
    Med Teach 31:1047-55. 2009
    ..The adoption of a common international vocabulary to describe educational processes means Italy will be able to participate more fully in the European medical education debate in future...
  58. ncbi request reprint Antisperm immunity in assisted reproduction
    Francesco Lombardo
    The University Laboratory of Seminology and Immunology of Reproduction, Department of Physiopathology, University of Rome La Sapienza, 00161 Rome, Italy
    J Reprod Immunol 62:101-9. 2004
    ..As immunological infertility is relatively rare, literature in the field is quite scarce and more studies need to be conducted to confirm that embryo quality is not impaired...
  59. ncbi request reprint Psychosocial factors discriminate oligozoospermic from normozoospermic men
    Luigi De Gennaro
    Department of Psychology, University of Rome La Sapienza, Rome, Italy
    Fertil Steril 79:1571-6. 2003
    ..To compare the profile of psychosocial variables in a group of oligozoospermic and normozoospermic men for assessing the hypothesis of a relationship between impaired seminal status and psychosocial factors...
  60. ncbi request reprint Effect of chemo- or radiotherapy on sperm parameters of testicular cancer patients
    Loredana Gandini
    Laboratory of Seminology and Immunology of Human Reproduction, Department of Medical Pathophysiology, Policlinico Umberto I, University of Rome La Sapienza, Rome, Italy
    Hum Reprod 21:2882-9. 2006
    ....
  61. ncbi request reprint Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study
    Susanna Morano
    Department of Clinical Sciences, Sapienza University, Rome, Italy
    Eur Urol 52:1768-74. 2007
    ..To investigate the synergic effect of propionyl L-carnitine (PLC) plus sildenafil in reducing monocyte oxidative activity and endothelial dysfunction markers in diabetic patients with erectile dysfunction (ED)...
  62. ncbi request reprint Testicular cancer and Hodgkin's disease: evaluation of semen quality
    Loredana Gandini
    University Laboratory of Seminology and Immunology of Reproduction, Department of Medical Pathophysiology, Policlinico Umberto I, University of Rome La Sapienza, 00161, Rome, Italy
    Hum Reprod 18:796-801. 2003
    ..The aim of our study was to establish whether there is a difference in semen quality between patients with testicular cancer (TC) and Hodgkin's disease (HD)...
  63. ncbi request reprint Circulating monocyte oxidative activity is increased in patients with type 2 diabetes and erectile dysfunction
    Susanna Morano
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    J Urol 177:655-9. 2007
    ..We investigated the relationship between oxidative stress and diabetic erectile dysfunction...
  64. doi request reprint Are apolipoprotein E alleles correlated with semen quality?
    D Paoli
    Laboratory of Seminology Sperm Bank, Department of Experimental Medicine, University of Rome La Sapienza, Rome, Italy
    Int J Androl 35:714-9. 2012
    ..This demonstrates once again that the use of number of children as an index of fertility is not indicative of real male reproductive capacity...
  65. doi request reprint Propionyl-L-carnitine, L-arginine and niacin in sexual medicine: a nutraceutical approach to erectile dysfunction
    D Gianfrilli
    Department of Experimental Medicine, Pathophysiology Section, Sapienza University of Rome, Rome, Italy
    Andrologia 44:600-4. 2012
    ..This study documents a considerable patient's interest toward nutritional supplementation--as first-line or adjunctive treatment to PDE5 inhibitors--that goes beyond the measurable increment in penile rigidity...
  66. ncbi request reprint Cortisol, dehydroepiandrosterone sulphate and dehydroepiandrosterone sulphate/cortisol ratio responses to physical stress in males are influenced by pubertal development
    L Di Luigi
    Unit of Endocrinology, Department of Health Sciences, University of Rome IUSM, Rome, Italy
    J Endocrinol Invest 29:796-804. 2006
    ....
  67. ncbi request reprint Is obesity protective for osteoporosis? Evaluation of bone mineral density in individuals with high body mass index
    E A Greco
    Dipartimento di Fisiopatologia Medica, Sapienza Universita di Roma, Policlinico Umberto I, 00161 Rome, Italy
    Int J Clin Pract 64:817-20. 2010
    ..The aim of this study was to characterise bone mineral density (BMD) in overweight (BMI > 25 < 29.9) and obese (BMI > 30) patients...
  68. doi request reprint Segmental testicular ischaemia: presentation, management and follow-up
    D Gianfrilli
    Department of Medical Pathophysiology DFM Fisiopatologia Medica, Sapienza University, Rome, Italy
    Int J Androl 32:524-31. 2009
    ..There are sufficient data to assert that a surveillance strategy is safe and feasible. We speculate that the defects in folate metabolism may pre-dispose individuals to the development of testicular infarction and infertility...
  69. ncbi request reprint Androgenic-anabolic steroids abuse in males
    L Di Luigi
    Unit of Endocrinology, Department of Human Movement and Sport Sciences, University Institute of Motor Sciences, Rome, Italy
    J Endocrinol Invest 28:81-4. 2005
    ..All physicians must be aware about the large diffusion and side effects related to AAS non-therapeutic use, in order to discover clinical signs of AAS abuse and/or to start adequate preventive and/or therapeutic actions...
  70. ncbi request reprint Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage
    L Gandini
    Department of Medical Pathophysiology, University of Rome, Rome, Italy
    Hum Reprod 19:1409-17. 2004
    ..It has been reported that sperm chromatin structure assay (SCSA) identified thresholds for negative pregnancy outcome after ART when the DNA fragmentation index (DFI), previously known as COMPalphat, was >30%...
  71. doi request reprint Testicular tumors as a possible cause of antisperm autoimmune response
    Donatella Paoli
    Department of Medical Pathophysiology, University of Rome La Sapienza, Rome, Italy
    Fertil Steril 91:414-9. 2009
    ..To evaluate the presence of antisperm antibodies in testicular cancer patients 1 month after orchiectomy and before radiotherapy or chemotherapy...
  72. pmc Detection of four diabetes specific autoantibodies in a single radioimmunoassay: an innovative high-throughput approach for autoimmune diabetes screening
    C Tiberti
    Department of Clinical Sciences, University of Rome Sapienza, Rome, Italy
    Clin Exp Immunol 166:317-24. 2011
    ..It appears to be particularly appropriate as a first-line approach for large-scale population-based screenings of anti-islet autoimmunity...
  73. doi request reprint Reduced artery diameters in Klinefelter syndrome
    C Foresta
    Department of Molecular Medicine, Section of Clinical Pathology and Center for Human Reproduction Pathology, University of Padova, Padova, Italy
    Int J Androl 35:720-5. 2012
    ..We have not an explanation for this phenomenon, even if a possible involvement of genes controlling the development of vascular system might be hypothesized, and further research is required to verify this hypothesis...
  74. doi request reprint Metabolic syndrome and erectile dysfunction among obese non-diabetic subjects
    A Gatti
    Department of Clinical Sciences, Sapienza University, Rome, Italy
    J Endocrinol Invest 32:542-5. 2009
    ..To investigate whether MS is associated with erectile dysfunction (ED) among obese non diabetic individuals...
  75. ncbi request reprint Functional anatomy of the human vagina
    G D'amati
    Department of Experimental Medicine and Pathology, 1st University of Rome, La Sapienza, Rome, Italy
    J Endocrinol Invest 26:92-6. 2003
    ..However, it is now apparent that modern sexology cannot be truly 'medical' if female sexual anatomy and the physiology of female sexual response are unknown...
  76. ncbi request reprint Beta-chemokine receptors 5 and 3 are expressed on the head region of human spermatozoon
    Barbara Muciaccia
    Department of Histology and Medical Embryology, and Centro di Eccellenza Biologia e Medicina Molecolare, University of Rome La Sapienza, Rome, Italy
    FASEB J 19:2048-50. 2005
    ..Finally, both CCR5 and CCR3 expressed on the sperm cell surface may be involved in HIV-1 adhesion to spermatozoa, thus allowing these cells to perform as virion cellular carriers during sexual transmission of HIV-1 infection...
  77. ncbi request reprint Introduction to the integrated model: medical, surgical and psychological therapies for the couple
    E A Jannini
    Course of Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
    J Endocrinol Invest 26:128-31. 2003
    ..Considering the growing complexity of therapies for sexual symptoms and diseases, there seems to be a need for the new professional figure of the medical sexologist...
  78. ncbi request reprint Sexological approach to ejaculatory dysfunction
    E A Jannini
    Course of Medical Sexology, Department of Experimental Medicine, University of L Aquila, Italy
    Int J Androl 25:317-23. 2002
    ....
  79. doi request reprint The application of digital pulse amplitude tonometry to the diagnostic investigation of endothelial dysfunction in men with erectile dysfunction
    A Aversa
    Department of Medical Pathophysiology, Sapienza Universita di Roma, Italy
    Andrologia 43:9-15. 2011
    ....
  80. doi request reprint Acupuncture in clinical and experimental reproductive medicine: a review
    G Franconi
    Endocrinology Unit, S Eugenio and CTO Hospitals, Tor Vergata University, Rome, Italy
    J Endocrinol Invest 34:307-11. 2011
    ....
  81. ncbi request reprint Sexual inactivity results in reversible reduction of LH bioavailability
    E Carosa
    Division of Endocrinology and Reproductive Medicine, Department of Experimental Medicine, University of L Aquila, Italy
    Int J Impot Res 14:93-9; discussion 100. 2002
    ..Because biopotency of pituitary hormones is controlled by the hypothalamus, LH hypoactivity should be due to the hypothalamic functional damage associated to the psychological disturbances which unavoidably follow sexual inactivity...
  82. ncbi request reprint Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin
    Alessia Belmonte
    Department of Surgery, University Tor Vergata, Rome, Italy
    J Soc Gynecol Investig 12:570-7. 2005
    ....
  83. ncbi request reprint Renal aplastic dysplasia and ipsilateral ectopic ureter obstructing the seminal via: a possible cause of male infertility: Part 2
    Antonio Carbone
    Neuro urology unit, University of Rome La Sapienza Polo Pontino, Rome, Italy
    Eur Urol 52:600. 2007
  84. ncbi request reprint Pre-receptorial regulation of steroid hormones in bone cells: insights on glucocorticoid-induced osteoporosis
    Silvia Pierotti
    Department of Medical Pathophysiology, University of Rome La Sapienza, Viale del Policlinico 155, Rome, Italy
    J Steroid Biochem Mol Biol 108:292-9. 2008
    ..The different kinetics of 11beta-HSD1 at various stage of differentiation and the GC-dependency of enzymatic activity have been presented...
  85. ncbi request reprint Renal aplastic dysplasia and ipsilateral ectopic ureter obstructing the seminal via: a possible cause of male infertility: Part 2
    Antonio Carbone
    Neuro urology unit, University of Rome La Sapienza Polo Pontino, Rome, Italy
    Eur Urol 52:600-1. 2007
  86. ncbi request reprint PHGPx in spermatogenesis: how many functions?
    Rossella Puglisi
    Department of Histology and Medical Embryology, University of Rome La Sapienza, 00161 Rome, Italy
    Contraception 72:291-3. 2005
    ..The data are discussed in light of the idea that PHGPx is a moonlighting protein, changing roles depending on the intracellular localization, expression in a specific cell type and different partners which it interacts with...
  87. doi request reprint Male hypogonadism
    Andrea M Isidori
    Department of Medical Pathophysiology DFM Fisiopatologia Medica, Sapienza University of Rome, Rome, Italy
    Pituitary 11:171-80. 2008
    ..A practical hands-on guide on how to perform these tests is also provided...
  88. ncbi request reprint HIV-1 chemokine co-receptor CCR5 is expressed on the surface of human spermatozoa
    Barbara Muciaccia
    Department of Histology and Medical Embryology, University La Sapienza, Rome, Italy
    AIDS 19:1424-6. 2005
    ..CCR5 expressed on the sperm cell surface may allow sperm to act as virion cellular carriers during the sexual transmission of HIV-1 infection...
  89. ncbi request reprint Renal aplastic dysplasia and ipsilateral ectopic ureter obstructing the seminal via: a possible cause of male infertility
    Antonio Carbone
    Neuro urology unit, University of Rome La Sapienza Polo Pontino, Rome, Italy
    Eur Urol 52:268-72. 2007
    ..Clinical and physical assessment including transrectal ultrasound and magnetic resonance imaging are proposed as a comprehensive algorithm for the diagnostic evaluation of the pelvic cystic masses...
  90. ncbi request reprint Molecular and clinical characterization of Y chromosome microdeletions in infertile men: a 10-year experience in Italy
    Alberto Ferlin
    University of Padova, Department of Histology, Microbiology and Medical Biotechnologies, Centre for Male Gamete Cryopreservation, Via Gabelli 63, 35121 Padova, Italy
    J Clin Endocrinol Metab 92:762-70. 2007
    ..However, despite the progresses in the biology of this chromosome, a number of molecular and clinical concerns are not supported by definitive data...
  91. ncbi request reprint Native specific activity of glutathione peroxidase (GPx-1), phospholipid hydroperoxide glutathione peroxidase (PHGPx) and glutathione reductase (GR) does not differ between normo- and hypomotile human sperm samples
    Federica Tramer
    Department of Biochemistry, Biophysics and Macromolecular Chemistry, University of Trieste, Italy
    Int J Androl 27:88-93. 2004
    ..These results are discussed and compared with recent literature data on both rescued and native PHGPx specific activity in human spermatozoa, as well as with data obtained for GPx in human seminal plasma...
  92. doi request reprint The type 5 phosphodiesterase inhibitor tadalafil influences salivary cortisol, testosterone, and dehydroepiandrosterone sulphate responses to maximal exercise in healthy men
    Luigi Di Luigi
    Unit of Endocrinology, Department of Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00194 Rome, Italy
    J Clin Endocrinol Metab 93:3510-4. 2008
    ....
  93. ncbi request reprint Mice overexpressing the mitochondrial phospholipid hydroperoxide glutathione peroxidase in male germ cells show abnormal spermatogenesis and reduced fertility
    Rossella Puglisi
    Department of Histology and Medical Embryology, Sapienza University of Rome, Via A Scarpa 14, 00161 Roma, Italy
    Endocrinology 148:4302-9. 2007
    ..Present findings in the mouse may be of interest to human male fertility...
  94. ncbi request reprint Treatment of sexual dysfunctions secondary to male infertility with sildenafil citrate
    Emmanuele A Jannini
    Fertil Steril 81:705-7. 2004
    ..Two pregnancies were obtained after sildenafil administration...
  95. ncbi request reprint Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patients
    Cesare Carani
    Department of Endocrinology, University of Modena, Italy
    J Clin Endocrinol Metab 90:6472-9. 2005
    ..Thyroid hormones have a dramatic effect on human behavior. However, their role on sexual behavior and performance has seldom been investigated in men...
  96. ncbi request reprint Subclinical erectile dysfunction: proposal for a novel taxonomic category in sexual medicine
    Emmanuele A Jannini
    Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
    J Sex Med 3:787-93; discussion 794. 2006
    ..In addition, we suggest research into biochemical markers to define this condition, which we have named subclinical erectile dysfunction...
  97. ncbi request reprint Changes in serum insulin-like factor 3 during normal male puberty
    Alberto Ferlin
    University of Padova, Department of Histology, Microbiology and Medical Biotechnologies, Centre for Male Gamete Cryopreservation, Via Gabelli 63, 35121 Padova, Italy
    J Clin Endocrinol Metab 91:3426-31. 2006
    ..However, the secretion and regulation of INSL3 during puberty is unknown...
  98. ncbi request reprint Enzymatic and immunochemical evaluation of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in testes and epididymal spermatozoa of rats of different ages
    Federica Tramer
    Department of Biochemistry, Biophysics and Macromolecular Chemistry, University of Trieste, Trieste, Italy
    Int J Androl 25:72-83. 2002
    ..The subcellular distribution of PHGPx is qualitatively, but not quantitatively, unchanged during ageing. These different behaviours are compared and discussed...
  99. ncbi request reprint Characterization of human sperm
    Andrea Lenzi
    Hum Reprod 17:842; author reply 843. 2002
  100. ncbi request reprint New perspectives in the pharmacotherapy of erectile dysfunction
    Emmanuele A Jannini
    Department of Experimental Medicine, Course of Medical Sexology, University of L Aquila, 67100 L Aquila, Italy
    IDrugs 6:1165-72. 2003
    ..New treatments and more effective drugs are expected in the near future because of the rapid expansion of research into erection regulation mechanisms and epidemiological studies...