Research Topics
| R LencioniSummaryAffiliation: University of Pisa Country: Italy Publications
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Detail Information
Publications
Tissue harmonic and contrast-specific imaging: back to gray scale in ultrasoundRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
Eur Radiol 12:151-65. 2002..It is foreseen that the new gray-scale US techniques will rapidly become a tool in numerous clinical scenarios...
Electrodes and multiple electrode systems for radio frequency ablation: a proposal for updated terminologyStefaan Mulier
Department of Surgery, University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium
Adv Exp Med Biol 574:57-73. 2006..This terminology provides an exact and complete description of the versatile novel multiple electrode systems...
Management of hepatocellular carcinoma with transarterial chemoembolization in the era of systemic targeted therapyRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Hepatology and Liver Transplantation, Pisa University Hospital, Via Paradisa 2, Building No 29, Pisa 56124, Italy
Crit Rev Oncol Hematol 83:216-24. 2012..The synergistic combination of TACE plus sorafenib represents a promising opportunity for tumor control...
Image-guided thermal ablation of hepatocellular carcinomaRiccardo Lencioni
Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Crit Rev Oncol Hematol 66:200-7. 2008....
Percutaneous ablation of hepatocellular carcinoma: state-of-the-artRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Italy
Liver Transpl 10:S91-7. 2004..Further investigation is warranted to clarify whether current RF technology could offer improved results in patients with intermediate-stage HCC...
Surveillance and early diagnosis of hepatocellular carcinomaRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Hepatology and Infectious Diseases, University of Pisa, Pisa, Italy
Dig Liver Dis 42:S223-7. 2010..If the biopsy is negative for HCC, patients should be followed-up by imaging studies performed at 3-month intervals until the nodule either disappears, enlarges, or displays diagnostic characteristics of HCC...
Clinical impact of Resovist-enhanced MRI: results of an Italian multicenter trialRiccardo Lencioni
Oncology Department, Division of Diagnostic and Interventional Radiology, University of Pisa, Via Roma 67, 56126 Pisa, Italy
Eur Radiol 14:C10. 2004
Loco-regional interventional treatment of hepatocellular carcinoma: techniques, outcomes, and future prospectsRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Pisa University Hospital and School of Medicine, Pisa, Italy
Transpl Int 23:698-703. 2010..Clinical trials focused on combining interventional treatment with systemically active drugs are ongoing. The outcomes of such studies are eagerly awaited, as they have the potential to revolutionize treatment of HCC...
Impact of European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) guidelines on the use of contrast agents in liver ultrasoundRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy
Eur Radiol 16:1610-3. 2006..We discuss the impact of EFSUMB guidelines on diagnostic protocols currently adopted in liver imaging...
Guidelines for imaging focal lesions in liver cirrhosisRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, IT 56126, Pisa, Italy
Expert Rev Gastroenterol Hepatol 2:697-703. 2008..However, even optimized imaging techniques remain relatively insensitive for the detection of tiny satellite nodules associated with the main tumor...
Modified RECIST (mRECIST) assessment for hepatocellular carcinomaRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Hepatology, and Infectious Diseases, University of Pisa, Pisa, Italy
Semin Liver Dis 30:52-60. 2010..They are referred to herein as the modified RECIST assessment (mRECIST). Further studies are needed to confirm the accuracy of this measurement compared with conventional gold standards such as pathologic studies of explanted livers...
Percutaneous image-guided radiofrequency ablation in the therapeutic management of hepatocellular carcinomaR Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, I 56126 Pisa, Italy
Abdom Imaging 30:401-8. 2005..This report reviews the current status of percutaneous, image-guided RFA in the therapeutic management of HCC...
Hepatocellular carcinoma: new options for image-guided ablationRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Hepatology, and Infectious Diseases, Pisa University School of Medicine, Cisanello Hospital, Building 30C, Suite 197, 56124 Pisa, Italy
J Hepatobiliary Pancreat Sci 17:399-403. 2010....
Contrast-enhanced ultrasound in the diagnosis of hepatocellular carcinomaRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, Cisanello University Hospital, Via Paradisa 2, University of Pisa, Pisa, Italy
J Hepatol 48:848-57. 2008..Hence, CT or MR imaging are still mandatory for proper intrahepatic staging of the disease...
Percutaneous image-guided radiofrequency ablation of liver tumorsRiccardo Lencioni
Department of Hepatology and Liver Transplantation, Pisa University Hospital, Italy
Abdom Imaging 34:547-56. 2009..In this article, we review technique, indications, and clinical results of percutaneous RF ablation in the treatment of HCC and colorectal hepatic metastases...
Magnetic resonance imaging of liver tumorsRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I-56126 Pisa, Italy
J Hepatol 40:162-71. 2004
European federation of societies for ultrasound in medicine and biology (EFSUMB) guidelines for the use of contrast agents in liver ultrasound: what is the impact in clinical practice?Riccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, IT 56126 Pisa, Italy
Eur Radiol 15:E98-103. 2005....
Radiofrequency ablation of liver cancerRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Tech Vasc Interv Radiol 10:38-46. 2007..In this article, we review technique, indications, and clinical results of percutaneous RF ablation in the treatment of HCC and colorectal hepatic metastases...
Clinical management of focal liver lesions: the key role of real-time contrast-enhanced USRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Italy
Eur Radiol 17:F73-9. 2007....
Doxorubicin-eluting bead-enhanced radiofrequency ablation of hepatocellular carcinoma: a pilot clinical studyRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology and Radiology, Cisanello University Hospital Building No 9, Via Paradisa 2, IT 56124 Pisa, Italy
J Hepatol 49:217-22. 2008..We aimed to assess safety and efficacy of doxorubicin-eluting bead (DEB)-enhanced RF ablation in the treatment of human hepatocellular carcinoma (HCC)...
Response to radiofrequency ablation of pulmonary tumours: a prospective, intention-to-treat, multicentre clinical trial (the RAPTURE study)Riccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Lancet Oncol 9:621-8. 2008..The purpose of this study was to identify the feasibility, safety, and effectiveness of percutaneous radiofrequency ablation of malignant lung tumours...
Treatment of intermediate/advanced hepatocellular carcinoma in the clinic: how can outcomes be improved?Riccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Hepatology, and Infectious Diseases, Pisa University School of Medicine, Cisanello Hospital, Pisa, Italy
Oncologist 15:42-52. 2010..It is hoped that findings from the GIDEON study along with phase III RCT data will lead to better outcomes for patients with intermediate-advanced HCC...
Single-session percutaneous ethanol ablation of early-stage hepatocellular carcinoma with a multipronged injection needle: results of a pilot clinical studyRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Cisanello University Hospital, Building No 30C, Via Paradisa 2, IT 56124, Pisa, Italy
J Vasc Interv Radiol 21:1533-8. 2010..To investigate the feasibility, safety, and efficacy of single-session ethanol ablation with multipronged needles in the treatment of early-stage hepatocellular carcinoma (HCC)...
Contrast-induced nephropathy in patients undergoing computed tomography (CONNECT) - a clinical problem in daily practice? A multicenter observational studyRiccardo Lencioni
Department of Liver Transplantation, Hepatology, and Infectious Diseases, Pisa University Hospital, Italy
Acta Radiol 51:741-50. 2010....
Design and rationale for the non-interventional Global Investigation of Therapeutic DEcisions in Hepatocellular Carcinoma and Of its Treatment with Sorafenib (GIDEON) studyR Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Hepatology and Infectious Diseases, Pisa University School of Medicine, Cisanello Hospital, Pisa, Italy
Int J Clin Pract 64:1034-41. 2010....
Loco-regional treatment of hepatocellular carcinomaRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Hepatology, and Infectious Diseases, Pisa University Hospital, Pisa, Italy
Hepatology 52:762-73. 2010..The outcomes of these trials are eagerly awaited, because they have the potential to revolutionize the treatment of HCC...
Assessment of therapeutic effect of liver tumor ablation proceduresC Bartolozzi
Division of Diagnostic and Interventional Radiology, Department of Oncology, University of Pisa, Via Roma 67, Pisa I 56125, Italy
Hepatogastroenterology 48:352-8. 2001..Peripheral inflammatory reaction following ablation procedures should not be misinterpreted as tumor progression...
Combination of interventional therapies in hepatocellular carcinomaR Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, University of Pisa, Via Roma 67, Pisa I 56125, Italy
Hepatogastroenterology 48:8-14. 2001..5-8.5 cm in diameter was achieved in 82% of cases in the absence of major complications. This new technique seems to have the potential to replace other interventional methods for the treatment of large hepatocellular carcinoma...
Percutaneous ablation of liver malignancies: imaging evaluation of treatment responseD Cioni
Department of Oncology Transplants, Division of Diagnostic and Interventional Radiology, University of Pisa, Via Roma 67, I-56125, Pisa, Italy
Eur J Ultrasound 13:73-93. 2001..Peripheral inflammatory reaction following ablation procedures, that shows itself as an enhancing halo along the necrotic area boundary on spiral CT or dynamic MR images, should not be misinterpreted as tumor progression...
Detection of colorectal liver metastases: prospective comparison of unenhanced and ferumoxides-enhanced magnetic resonance imaging at 1.5 T, dual-phase spiral CT, and spiral CT during arterial portographyR Lencioni
Department of Oncology, University of Pisa, Italy
MAGMA 7:76-87. 1998..Further investigation is needed to clarify whether MR imaging with use of ferumoxides might replace spiral CTAP for preoperative evaluation of liver resection candidates...
Clinical management of hepatic malignancies: ferucarbotran-enhanced magnetic resonance imaging versus contrast-enhanced spiral computed tomographyRiccardo Lencioni
Department of Radiology, University of Pisa, Pisa, Italy
Dig Dis Sci 50:533-7. 2005..0167). Ferucarbotran-enhanced MR imaging is superior to spiral CT in clinical management of patients with suspected hepatic malignancy...
First interim analysis of the GIDEON (Global Investigation of therapeutic decisions in hepatocellular carcinoma and of its treatment with sorafeNib) non-interventional studyR Lencioni
Division of Diagnostic Imaging and Intervention, Pisa University Hospital and School of Medicine, Pisa, Italy
Int J Clin Pract 66:675-83. 2012....
Focal liver lesions: MR imaging-pathologic correlationC Bartolozzi
Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Italy
Eur Radiol 11:1374-88. 2001..Moreover, in certain tumor histotypes, such as hepatocellular carcinoma, careful analysis of lesion signal intensity may help predict the degree of tumor differentiation...
Loco-regional treatment of hepatocellular carcinoma in the era of molecular targeted therapiesRiccardo Lencioni
Division of Diagnostic Imaging and Intervention, Department of Liver Transplantation, Hepatology, and Infectious Diseases, Pisa University School of Medicine, Pisa, Italy
Oncology 78:107-12. 2010..Clinical trials focused on combining interventional treatment with systemically active drugs are ongoing. The outcomes of such studies are eagerly awaited, as they have the potential to revolutionize treatment of HCC...
Detection of colorectal liver metastases: a prospective multicenter trial comparing unenhanced MRI, MnDPDP-enhanced MRI, and spiral CTCarlo Bartolozzi
Department of Radiology, University of Pisa, Via Roma 67, 56100, Pisa, Italy
Eur Radiol 14:14-20. 2004..0023) and unenhanced MRI (21 of 44 cases, p=0.0013). MnDPDP-enhanced MRI is superior to unenhanced MRI and spiral CT in the detection of hepatic colorectal metastases...
Thermal ablation of lung tissue: in vivo experimental comparison of microwave and radiofrequencyLaura Crocetti
Division of Radiodiagnostic, Department of Oncological and Radiological Sciences, Pisa University Hospital, Pisa, Italy
Cardiovasc Intervent Radiol 33:818-27. 2010..Feasibility and safety of MW and RF ablation are similar in a lung rabbit model. MW ablation produces a greater damage to peripheral small vessels inducing thrombosis...
Quality improvement guidelines for radiofrequency ablation of liver tumoursLaura Crocetti
Division of Diagnostic Imaging and Intervention, Department of Hepatology, Liver Transplants, and Infectious Diseases, University of Pisa, Pisa, Italy
Cardiovasc Intervent Radiol 33:11-7. 2010..The most important processes of care are (1) patient selection, (2) performing the procedure, and (3) monitoring the patient. The outcome measures or indicators for these processes are indications, success rates, and complication rates...
Thermal ablation of hepatocellular carcinomaLaura Crocetti
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Cancer Imaging 8:19-26. 2008....
Imaging diagnosisRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, I 56125 Pisa, Italy
Semin Liver Dis 25:162-70. 2005..These examinations have replaced invasive procedures, such as lipiodol CT, but remain relatively insensitive for the detection of tiny HCC lesions and tumor vascular invasion into peripheral portal vein branches...
Radiofrequency ablation of pulmonary tumorsLaura Crocetti
Division of Diagnostic Imaging and Intervention, Department of Liver Transplants, Hepatology and Infectious Diseases, Pisa University School of Medicine, Italy
Eur J Radiol 75:23-7. 2010....
Lung radiofrequency ablation: in vivo experimental study with low-perfusion-rate multitined electrodesLaura Crocetti
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplant and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I 56125 Pisa, Italy
Cardiovasc Intervent Radiol 31:610-8. 2008..In conclusion, lung RF ablation performed in an in vivo animal model using low-perfusion-rate, expandable, multitined electrodes is feasible and safe. No severe damage to adjacent structures was demonstrated...
Colorectal cancer: role of CT colonography in preoperative evaluation after incomplete colonoscopyEmanuele Neri
Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I 56100 Pisa, Italy
Radiology 223:615-9. 2002..To evaluate computed tomographic (CT) colonography in patients with clinical suspicion of colorectal cancer and in whom colonoscopy was incomplete...
Percutaneous radiofrequency ablation of hepatic colorectal metastases: technique, indications, results, and new promisesRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Invest Radiol 39:689-97. 2004..In this article, we review technique, indications, clinical results, and future prospects of RF ablation in the therapeutic management of metastatic colorectal cancer patients...
Radiofrequency ablation of lung malignancies: where do we stand?Riccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I 56126, Pisa, Italy
Cardiovasc Intervent Radiol 27:581-90. 2004..This article gives an overview of lung RF ablation, discussing experimental animal findings, rationale for clinical application, technique and methodology, clinical results, and complications...
Early-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous image-guided radiofrequency ablationRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I 56125 Pisa, Italy
Radiology 234:961-7. 2005....
A critical appraisal of the literature on local ablative therapies for hepatocellular carcinomaRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, Pisa I 56125, Italy
Clin Liver Dis 9:301-14, viii. 2005..Further randomized trials are needed to establish the clinical efficacy of radiofrequency ablation with respect to other percutaneous treatments and to devise an unbiased therapeutic strategy...
Percutaneous ablation of hepatocellular carcinomaRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, University of Pisa, Rome, Italy
Recent Results Cancer Res 167:91-105. 2006
Biliary and reticuloendothelial impairment in hepatocarcinogenesis: the diagnostic role of tissue-specific MR contrast mediaCarlo Bartolozzi
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplant and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, 56125, Pisa, Italy
Eur Radiol 17:2519-30. 2007....
Targeting liver lesions for radiofrequency ablation: an experimental feasibility study using a CT-US fusion imaging systemLaura Crocetti
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplant and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Invest Radiol 43:33-9. 2008....
Radiofrequency thermal ablation of hepatocellular carcinoma: using contrast-enhanced harmonic power doppler sonography to assess treatment outcomeD Cioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I-56125 Pisa, Italy
AJR Am J Roentgenol 177:783-8. 2001....
Pulmonary radiofrequency ablation in a single lung patientM C Ambrogi
Division of Thoracic Surgery, Cardiac and Thoracic Department, Pisa, Italy
Thorax 61:828-9. 2006..The procedure was performed under CT guidance and was uneventful. At follow up 9 months later the tumour appeared to have ablated. To our knowledge, no similar case has previously been reported in the literature...
Noninvasive assessment of renal artery stenosis: current imaging protocols and future directions in ultrasonographyR Lencioni
Division of Diagnostic and Interventional Radiology, University of Pisa, Italy
J Comput Assist Tomogr 23:S95-100. 1999..State-of-the-art contrast-enhanced Doppler ultrasound seems to have the potential to become a useful screening test for patients at risk from renovascular hypertension...
Endorectal coil MR imaging findings in hemospermiaR Lencioni
Department of Radiology, University of Pisa, Italy
MAGMA 8:91-7. 1999....
Ultrasound imaging of focal liver lesions with a second-generation contrast agentRiccardo Lencioni
Department of Oncology, Transplants, and Advanced Technologies in Medicine, University of Pisa, Italy
Acad Radiol 9:S371-4. 2002
Large regenerative nodules in Budd-Chiari syndrome and other vascular disorders of the liver: CT and MR imaging findings with clinicopathologic correlationGiuseppe Brancatelli
Department of Radiology, University of Pittsburgh Medical Center, UPMC-Presbyterian, 200 Lothrop St, Pittsburgh, PA 15213, USA
AJR Am J Roentgenol 178:877-83. 2002..CT and MR imaging show consistent features of the nodules and the surrounding liver that may allow distinction of Budd-Chiari nodules from other types of hypervascular hyperplastic or dysplastic nodules...
Benign regenerative nodules in Budd-Chiari syndrome and other vascular disorders of the liver: radiologic-pathologic and clinical correlationGiuseppe Brancatelli
Department of Radiology, University of Pittsburgh Medical Center, UPMC Presbyterian, 200 Lothrop St, PA 15213, USA
Radiographics 22:847-62. 2002..Understanding the clinical setting and imaging appearance of large regenerative nodules can help avoid misdiagnosis as other hypervascular masses...
Design and endpoints of clinical trials in hepatocellular carcinomaJosep M Llovet
HCC Translational Research Lab, Barcelona Clinic Liver Cancer Group, Liver Unit, Hospital Clinic, CIBERehd, Institute for Biomedical Investigations August Pi Sunyer, Villarroel 170, 08036 Barcelona, Catalonia, Spain
J Natl Cancer Inst 100:698-711. 2008..These surrogate markers may help to enrich study populations and maximize the cost-benefit ratio of trial execution. Design and conduct of phase 3 trials should be coordinated by centers with appropriate expertise in HCC...
How to report and compare complications of image-guided ablation therapies: comments on seeding and the use of a sole common denominator for liver tumorsVincenzo Arienti
Radiology 241:625-6; author reply 626-7. 2006
Electrodes and multiple electrode systems for radiofrequency ablation: a proposal for updated terminologyStefaan Mulier
Department of Surgery, University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium
Eur Radiol 15:798-808. 2005..This terminology provides an exact and complete description of the versatile novel multiple electrode systems...
Percutaneous ethanol injection for hepatocellular carcinoma: alive or dead?Riccardo Lencioni
J Hepatol 43:377-80. 2005
Editorial on Machi et al. "long term follow-up outcome of patients undergoing radiofrequency ablation for unresectable hepatocellular carcinoma"Riccardo Lencioni
World J Surg 29:1363. 2005
Pulmonary radiofrequency ablation--an international study surveyKarin Steinke
Department of Surgery, UNSW, The St. George Hospital, Sydney, Australia
Anticancer Res 24:339-43. 2004....
