Maria Giuseppa Leggio

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. doi request reprint Cognitive sequencing impairment in patients with focal or atrophic cerebellar damage
    M G Leggio
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185 Roma, Italy
    Brain 131:1332-43. 2008
  2. ncbi request reprint Environmental enrichment provides a cognitive reserve to be spent in the case of brain lesion
    Laura Mandolesi
    IRCCS Santa Lucia Foundation, Rome, Italy
    J Alzheimers Dis 15:11-28. 2008
  3. doi request reprint The cerebellar cognitive profile
    Anna M Tedesco
    Department of Psychology, University of Rome La Sapienza, 00185 Rome, Italy
    Brain 134:3672-86. 2011
  4. ncbi request reprint NMDA receptor activity in learning spatial procedural strategies I. The influence of hippocampal lesions
    Maria G Leggio
    IRCCS S Lucia, Rome, Italy
    Brain Res Bull 70:347-55. 2006
  5. ncbi request reprint A new paradigm to analyze observational learning in rats
    Maria G Leggio
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185, Rome, Italy
    Brain Res Brain Res Protoc 12:83-90. 2003
  6. ncbi request reprint Environmental enrichment promotes improved spatial abilities and enhanced dendritic growth in the rat
    Maria Giuseppa Leggio
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185 Rome, Italy
    Behav Brain Res 163:78-90. 2005
  7. ncbi request reprint Layer and regional effects of environmental enrichment on the pyramidal neuron morphology of the rat
    Francesca Gelfo
    I R C C S Santa Lucia Foundation, Rome, Italy
    Neurobiol Learn Mem 91:353-65. 2009
  8. doi request reprint On whether the environmental enrichment may provide cognitive and brain reserves
    Laura Petrosini
    Department of Psychology, University Sapienza of Rome, Rome, Italy
    Brain Res Rev 61:221-39. 2009
  9. ncbi request reprint Cerebellar contribution to spatial event processing: involvement in procedural and working memory components
    L Mandolesi
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185 Rome, Italy
    Eur J Neurosci 14:2011-22. 2001
  10. pmc Visuospatial abilities in cerebellar disorders
    M Molinari
    IRCCS S Lucia, Rome, Italy
    J Neurol Neurosurg Psychiatry 75:235-40. 2004

Collaborators

Detail Information

Publications22

  1. doi request reprint Cognitive sequencing impairment in patients with focal or atrophic cerebellar damage
    M G Leggio
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185 Roma, Italy
    Brain 131:1332-43. 2008
    ....
  2. ncbi request reprint Environmental enrichment provides a cognitive reserve to be spent in the case of brain lesion
    Laura Mandolesi
    IRCCS Santa Lucia Foundation, Rome, Italy
    J Alzheimers Dis 15:11-28. 2008
    ..Thus, rearing in an enriched environment results in the development of brain and cognitive reserves that reduce the cognitive impairment following forebrain lesions...
  3. doi request reprint The cerebellar cognitive profile
    Anna M Tedesco
    Department of Psychology, University of Rome La Sapienza, 00185 Rome, Italy
    Brain 134:3672-86. 2011
    ..Of the various cognitive domains, the ability to sequence was the most adversely affected in nearly all subjects, supporting the hypothesis that sequencing is a basic cerebellar operation...
  4. ncbi request reprint NMDA receptor activity in learning spatial procedural strategies I. The influence of hippocampal lesions
    Maria G Leggio
    IRCCS S Lucia, Rome, Italy
    Brain Res Bull 70:347-55. 2006
    ..These findings indicate that even in the absence of the hippocampal formation the NMDA receptor antagonist found a site of action to influence the acquisition of spatial procedures to search for the platform...
  5. ncbi request reprint A new paradigm to analyze observational learning in rats
    Maria G Leggio
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185, Rome, Italy
    Brain Res Brain Res Protoc 12:83-90. 2003
    ..The results obtained indicate that it is possible to learn complex behavioral strategies by observation using this new protocol. Furthermore, acquisition of the single facets that form the behavioral repertoire can be separately studied...
  6. ncbi request reprint Environmental enrichment promotes improved spatial abilities and enhanced dendritic growth in the rat
    Maria Giuseppa Leggio
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185 Rome, Italy
    Behav Brain Res 163:78-90. 2005
    ..Environmental enrichment provoked increased dendritic arborisation as well as increased density of dendritic spines in layer-III parietal pyramidal neurons...
  7. ncbi request reprint Layer and regional effects of environmental enrichment on the pyramidal neuron morphology of the rat
    Francesca Gelfo
    I R C C S Santa Lucia Foundation, Rome, Italy
    Neurobiol Learn Mem 91:353-65. 2009
    ..It is hypothesized that these multifaceted morphological EE effects are connected to the heavy involvement of a sensory-motor circuit engaged in the guidance of voluntary action and in motor learning activated by EE stimulation...
  8. doi request reprint On whether the environmental enrichment may provide cognitive and brain reserves
    Laura Petrosini
    Department of Psychology, University Sapienza of Rome, Rome, Italy
    Brain Res Rev 61:221-39. 2009
    ..As this is the fundamental assumption of the reserve hypothesis, it is possible that as human educational attainment and occupational status, environmental enrichment develops reserves to be spent in the case of a subsequent lesion...
  9. ncbi request reprint Cerebellar contribution to spatial event processing: involvement in procedural and working memory components
    L Mandolesi
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185 Rome, Italy
    Eur J Neurosci 14:2011-22. 2001
    ....
  10. pmc Visuospatial abilities in cerebellar disorders
    M Molinari
    IRCCS S Lucia, Rome, Italy
    J Neurol Neurosurg Psychiatry 75:235-40. 2004
    ..Cerebellar involvement in spatial data management has been suggested on experimental and clinical grounds...
  11. pmc Phonological grouping is specifically affected in cerebellar patients: a verbal fluency study
    M G Leggio
    Department of Psychology, University of Rome La Sapienza, Rome, Italy
    J Neurol Neurosurg Psychiatry 69:102-6. 2000
    ..The aim was to investigate the influence of cerebellar lesions on verbal fluency abilities with specific focus on the verbal searching strategies employed by patients with cerebellar damage...
  12. ncbi request reprint Verbal short-term store-rehearsal system and the cerebellum. Evidence from a patient with a right cerebellar lesion
    M C Silveri
    Neuropsychology Service, Institute of Neurology, Catholic University, Rome, Italy
    Brain 121:2175-87. 1998
    ..We conclude that the cerebellum takes part in the planning of speech production at a level that does not require an overt articulation...
  13. doi request reprint Environmental enrichment mitigates the effects of basal forebrain lesions on cognitive flexibility
    P De Bartolo
    IRCCS Santa Lucia Foundation, Via Ardeatina 304, Rome, Italy
    Neuroscience 154:444-53. 2008
    ..These findings demonstrate that rearing in an enriched environment can improve the ability to cope with brain damage suffered in adulthood...
  14. pmc Clusters of non-truncating mutations of P/Q type Ca2+ channel subunit Ca(v)2.1 causing episodic ataxia 2
    E Mantuano
    Institute of Neurobiology and Molecular Medicine, CNR, Rome, Italy
    J Med Genet 41:e82. 2004
  15. ncbi request reprint Cerebellar contribution to spatial event processing: do spatial procedures contribute to formation of spatial declarative knowledge?
    L Mandolesi
    Department of Psychology, University of Rome La Sapienza, Via dei Marsi 78, 00185 Rome, Italy IRCCS S Lucia, Via Ardeatina 306, 00179 Rome, Italy
    Eur J Neurosci 18:2618-26. 2003
    ..This finding suggests that no declarative spatial learning is possible without appropriate procedural spatial learning...
  16. ncbi request reprint Neuronal plasticity of interrelated cerebellar and cortical networks
    M Molinari
    Rehabilitation Hospital and Research Institute, Santa Lucia Foundation, Via Ardeatina 306, 00179, Rome, Italy
    Neuroscience 111:863-70. 2002
    ....
  17. ncbi request reprint Learning power of single behavioral units in acquisition of a complex spatial behavior: an observational learning study in cerebellar-lesioned rats
    A Graziano
    Department of Psychology, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Behav Neurosci 116:116-25. 2002
    ..These results indicate that the single facets that form the strategy repertoire can be independently acquired...
  18. pmc Representation of actions in rats: the role of cerebellum in learning spatial performances by observation
    M G Leggio
    Department of Psychology, University of Rome La Sapienza, 00185 Rome, Italy
    Proc Natl Acad Sci U S A 97:2320-5. 2000
    ..In conclusion, the present results provide strong support for a common neural basis in the observation of actions that are to be reproduced as well as in the actual production of the same actions...
  19. ncbi request reprint Cerebellar contribution to spatial event processing: characterization of procedural learning
    M G Leggio
    Department of Psychology, University of Rome La Sapienza, Italy
    Exp Brain Res 127:1-11. 1999
    ....
  20. ncbi request reprint The cerebellum in the spatial problem solving: a co-star or a guest star?
    L Petrosini
    Department of Psychology, University of Rome La Sapienza, Italy
    Prog Neurobiol 56:191-210. 1998
    ..These structures form an allocentric spatial system and an egocentric control system, that interlock to process the information involved in representing an object in the space...
  21. ncbi request reprint Cerebellar damage impairs detection of somatosensory input changes. A somatosensory mismatch-negativity study
    Domenico Restuccia
    I R C S S E Medea La Nostra Famiglia, Pasian di Prato, Udine, Italy
    Brain 130:276-87. 2007
    ..In conclusion, this study demonstrates the reliability of S-MMN recordings and indicates that subjects with cerebellar damage may be impaired in the cortical processing of incoming somatosensory inputs...
  22. ncbi request reprint Is the cerebellum involved in the visuo-locomotor associative learning?
    Laura Mandolesi
    University of Naples Parthenope, Italy
    Behav Brain Res 184:47-56. 2007
    ....