Marialuisa Lavitrano

Summary

Affiliation: University of Milano-Bicocca
Country: Italy

Publications

  1. pmc Diet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatment
    Marco Busnelli
    Department of Surgery and Interdisciplinary Medicine, University of Milano Bicocca, Milano, Italy
    PLoS ONE 8:e80588. 2013
  2. ncbi request reprint Methods for sperm-mediated gene transfer
    Marialuisa Lavitrano
    Department of Surgical Sciences, University of Milano Bicocca, Monza, Italy
    Methods Mol Biol 927:519-29. 2013
  3. ncbi request reprint Sperm mediated gene transfer in pig: Selection of donor boars and optimization of DNA uptake
    Marialuisa Lavitrano
    Dipartimento di Medicina Sperimentale, Universita La Sapienza, 00161 Roma, Italy
    Mol Reprod Dev 64:284-91. 2003
  4. ncbi request reprint Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs
    Marialuisa Lavitrano
    Department Medicina Sperimentale Ambientale e Biotecnologie Mediche, University of Milano Bicocca, Via Cadore, 48, 20052 Monza, Milano, Italy
    FASEB J 18:1093-5. 2004
  5. ncbi request reprint Sperm-mediated gene transfer
    Marialuisa Lavitrano
    Dipartimento di Scienze Chirurgiche e Terapia Intensiva, Universita di Milano, Bicocca, 20052 Milano, Italy
    Reprod Fertil Dev 18:19-23. 2006
  6. pmc Genetically modified pigs produced with a nonviral episomal vector
    Stefano Manzini
    Department of Surgical Sciences, University of Milano Bicocca, 20052 Milan, Italy
    Proc Natl Acad Sci U S A 103:17672-7. 2006
  7. doi request reprint Pathogenetic role of hypercholesterolemia in a novel preclinical model of vascular injury in pigs
    Marco Busnelli
    Department of Surgical Sciences, University of Milano Bicocca, Milano, Italy
    Atherosclerosis 207:384-90. 2009
  8. pmc Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation
    Marialuisa Lavitrano
    Dipartimento di Medicina Sperimentale, Universita La Sapienza, 00161 Roma, Italy
    Proc Natl Acad Sci U S A 99:14230-5. 2002
  9. ncbi request reprint Heme oxygenase-1 inhibition prevents intimal hyperplasia enhancing nitric oxide-dependent apoptosis of vascular smooth muscle cells
    Maria Grazia Cerrito
    Molecular Medicine Laboratory, University of Milano Bicocca, Monza, Italy
    Biol Pharm Bull 34:1204-14. 2011
  10. pmc GSK3A Is Redundant with GSK3B in Modulating Drug Resistance and Chemotherapy-Induced Necroptosis
    Emanuela Grassilli
    Department of Surgery and Traslational Medicine, Medical School, University of Milano Bicocca, Via Cadore 48, Monza, Italy BiOnSil srl, Via Cadore 48, Monza, Italy
    PLoS ONE 9:e100947. 2014

Collaborators

  • Marisa Donada
  • Isa M Stehle
  • Fritz H Bach
  • Magdi H Yacoub
  • Paolo Galli
  • Monica Forni
  • L Inglese
  • A Mancini
  • R T Smolenski
  • Leo E Otterbein
  • G M Biasi
  • Emanuele Cozzi
  • Fabio Gentilini
  • Mauro S Sandrin
  • Ken Suzuki
  • Alberto Cremonesi
  • Roberto Giovannoni
  • Maria Grazia Cerrito
  • Marco Busnelli
  • Emanuela Grassilli
  • Biagio Eugenio Leone
  • Maria Laura Bacci
  • Zain Khalpey
  • Alberto Froio
  • Stefano Manzini
  • Augusta Zannoni
  • Laura Masiero
  • Kameljit K Kalsi
  • Leonarda Ianzano
  • Massimo Giunti
  • Alessandra Scagliarini
  • Alessia Vargiolu
  • Michele Papa
  • Maria Rosaria Bianco
  • Nicole L Webster
  • Foy N Osborne
  • Pierluigi Donini
  • Paola Poggiali
  • Carola Missaglia
  • Sara Bonomo
  • Serena Bonin
  • Fabio Pisano
  • Giorgio Stanta
  • Gabriele Romano
  • Kristian Helin
  • Alessandro Cinti
  • Elena Federzoni
  • Robert Narloch
  • Lara Mainetti
  • Matteo Villa
  • Angela Liloia
  • Cristian Benatti
  • Gaetano Deleo
  • Ada H Y Yuen
  • Christopher G A McGregor
  • Hans J Lipps
  • Leda Dalprà
  • Eraldo Seren
  • Ewa M Slominska
  • Maria L Bacci
  • Riccardo Razzini
  • Ada H Yuen
  • Ian F C Mc Kenzie
  • Joanna Karbowska
  • Marlene L Rose
  • Zdzislaw Kochan
  • Massimo Macherini
  • Paolo Fantinati
  • Charlotte Lawson
  • Lisa Fusetti
  • Puspa Batten
  • Carmen Cimmino
  • Gian Luca Scoarughi

Detail Information

Publications21

  1. pmc Diet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatment
    Marco Busnelli
    Department of Surgery and Interdisciplinary Medicine, University of Milano Bicocca, Milano, Italy
    PLoS ONE 8:e80588. 2013
    ..Our aim was also to test the effect of high-dose statin treatment on these processes...
  2. ncbi request reprint Methods for sperm-mediated gene transfer
    Marialuisa Lavitrano
    Department of Surgical Sciences, University of Milano Bicocca, Monza, Italy
    Methods Mol Biol 927:519-29. 2013
    ....
  3. ncbi request reprint Sperm mediated gene transfer in pig: Selection of donor boars and optimization of DNA uptake
    Marialuisa Lavitrano
    Dipartimento di Medicina Sperimentale, Universita La Sapienza, 00161 Roma, Italy
    Mol Reprod Dev 64:284-91. 2003
    ..The results described provide significant advances in SMGT technology applied to pigs, so that transgenic pigs can be efficiently obtained. Mol...
  4. ncbi request reprint Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs
    Marialuisa Lavitrano
    Department Medicina Sperimentale Ambientale e Biotecnologie Mediche, University of Milano Bicocca, Via Cadore, 48, 20052 Monza, Milano, Italy
    FASEB J 18:1093-5. 2004
    ..We conclude that treatment with CO improves the energy status, prevents edema formation and apoptosis, and facilitates recovery in a clinically relevant model of cardiopulmonary bypass surgery...
  5. ncbi request reprint Sperm-mediated gene transfer
    Marialuisa Lavitrano
    Dipartimento di Scienze Chirurgiche e Terapia Intensiva, Universita di Milano, Bicocca, 20052 Milano, Italy
    Reprod Fertil Dev 18:19-23. 2006
    ....
  6. pmc Genetically modified pigs produced with a nonviral episomal vector
    Stefano Manzini
    Department of Surgical Sciences, University of Milano Bicocca, 20052 Milan, Italy
    Proc Natl Acad Sci U S A 103:17672-7. 2006
    ..These results are an important step forward in animal transgenesis and can provide the basis for the future development of germ-line gene therapy...
  7. doi request reprint Pathogenetic role of hypercholesterolemia in a novel preclinical model of vascular injury in pigs
    Marco Busnelli
    Department of Surgical Sciences, University of Milano Bicocca, Milano, Italy
    Atherosclerosis 207:384-90. 2009
    ....
  8. pmc Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation
    Marialuisa Lavitrano
    Dipartimento di Medicina Sperimentale, Universita La Sapienza, 00161 Roma, Italy
    Proc Natl Acad Sci U S A 99:14230-5. 2002
    ..These results show that our SMGT approach to transgenesis provides an efficient procedure for studies involving large animal models...
  9. ncbi request reprint Heme oxygenase-1 inhibition prevents intimal hyperplasia enhancing nitric oxide-dependent apoptosis of vascular smooth muscle cells
    Maria Grazia Cerrito
    Molecular Medicine Laboratory, University of Milano Bicocca, Monza, Italy
    Biol Pharm Bull 34:1204-14. 2011
    ..In the context of IH, the pro-apoptotic effect of NO on VSMC is increased in the absence of HO-1 and exerts therapeutic effects with a significant reduction in IH...
  10. pmc GSK3A Is Redundant with GSK3B in Modulating Drug Resistance and Chemotherapy-Induced Necroptosis
    Emanuela Grassilli
    Department of Surgery and Traslational Medicine, Medical School, University of Milano Bicocca, Via Cadore 48, Monza, Italy BiOnSil srl, Via Cadore 48, Monza, Italy
    PLoS ONE 9:e100947. 2014
    ....
  11. doi request reprint Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy
    Emanuela Grassilli
    Department of Surgery and Interdisciplinary Medicine, University of Milano Bicocca, Milano, Italy
    Clin Cancer Res 19:3820-31. 2013
    ..Identification of specific targets for the treatment of drug-resistant p53-null tumors would therefore increase the effectiveness of cancer therapy...
  12. ncbi request reprint Rationale and design of a multidisciplinary national real-world registry on carotid stenting: the Italian Registry for Carotid Stenting (RISC)
    Giorgio M Biasi
    Department of Surgical Sciences and Intensive Care, University of Milano Bicocca, Vascular Surgery Unit, San Gerardo Hospital, Monza, Italy
    J Endovasc Ther 13:214-20. 2006
    ..Considerable attention has been paid to the registry's quality control program to ensure scientific validation. An online database facilitates the collection of data with speed and accuracy...
  13. doi request reprint Head glands of Monogenoidea: morphology, functionality, and potentialities in industrial production of surgery bioadhesives
    Paolo Galli
    Department of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza 2, 20126 Milan, Italy
    J Parasitol 95:1330-41. 2009
    ..The potential use of monogenoidean cephalic secretions in the surgical field, and particularly in the production of bioadhesives, is suggested and critically supported by comparison with other available hemostatic agents...
  14. ncbi request reprint Species differences of endothelial extracellular nucleotide metabolism and its implications for xenotransplantation
    Ryszard T Smolenski
    Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middlesex, UB9 6JH, UK
    Pharmacol Rep 58:118-25. 2006
    ..These studies suggests that expression of human ecto-5'-nucleotidase in pigs genetically engineered for xenotransplantation could help to prolong graft survival...
  15. ncbi request reprint Reduction of hyperacute rejection and protection of metabolism and function in hearts of human decay accelerating factor (hDAF)-expressing pigs
    Ryszard T Smolenski
    Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middlesex, UB9 6JH, UK
    Cardiovasc Res 73:143-52. 2007
    ....
  16. ncbi request reprint Expression of human ecto-5'-nucleotidase in pig endothelium increases adenosine production and protects from NK cell-mediated lysis
    Foy N Osborne
    Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middlesex, UK
    Am J Transplant 5:1248-55. 2005
    ..We suggest that overexpression of E5'N in EC of transgenic pigs is a possible strategy to ameliorate rejection after xenotransplantation...
  17. ncbi request reprint Construction of a swine artificial chromosome: a novel vector for transgenesis in the pig
    Paola Poggiali
    Dipartimento di Biologia Cellulare e dello Sviluppo, University of Rome La Sapienza, Via dei Sardi, 70, Italy
    Biochimie 84:1143-50. 2002
    ..Possible applications as vectors for animal transgenesis are discussed...
  18. ncbi request reprint Multi-transgenic pigs expressing three fluorescent proteins produced with high efficiency by sperm mediated gene transfer
    Nicole L Webster
    The Austin Research Institute, Studley Road, Heidelberg, Victoria, Australia
    Mol Reprod Dev 72:68-76. 2005
    ..These results show that SMGT is an effective method for introducing multiple genes into pigs as shown by the simultaneous expression of three fluorescent proteins...
  19. ncbi request reprint Mammalian mismatches in nucleotide metabolism: implications for xenotransplantation
    Zain Khalpey
    Heart Science Centre, Imperial College London, Harefield, Middlesex, UB9 6JH, UK
    Mol Cell Biochem 304:109-17. 2007
    ..Supplementation of deficient precursors or application of inhibitors of nucleotide metabolism (e.g., allopurinol) or transgenic upregulation of E5'N may overcome some of these differences...
  20. ncbi request reprint Loss of ecto-5'nucleotidase from porcine endothelial cells after exposure to human blood: Implications for xenotransplantation
    Zain Khalpey
    Heart Science Centre, Imperial College at Harefield Hospital, Middlesex UB9 6JH, UK
    Biochim Biophys Acta 1741:191-8. 2005
    ..This effect is triggered by human humoral immune responses, and complement contributes but does not fully mediate E5'N depletion...
  21. ncbi request reprint Indication for carotid endarterectomy versus carotid stenting for the prevention of brain embolization from carotid artery plaques: in search of consensus
    Giorgio M Biasi
    J Endovasc Ther 13:578-91. 2006