Research Topics
| Virginia LanzottiSummaryAffiliation: University of Molise Country: Italy Publications
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Detail Information
Publications
The analysis of onion and garlicVirginia Lanzotti
Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
J Chromatogr A 1112:3-22. 2006..Particular attention was given to the different methodology developed to perform chemical analysis, including separation and structural elucidation...
Antimicrobial furostanol saponins from the seeds of Capsicum annuum L. var. acuminatumMaria Iorizzi
Dipartimento di Scienze e Tecnologie Agro alimentari, Ambientali e Microbiologiche, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
J Agric Food Chem 50:4310-6. 2002..Data indicated that the antiyeast activity was related to the combination of the oligosaccharide chain (S1, S2, or S3) with an O-methyl group at R(3) and the presence of a hydroxyl group at the C-2 position...
Saponins from Allium minutiflorum with antifungal activityElisa Barile
Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
Phytochemistry 68:596-603. 2007..No appreciable antibacterial activity was recorded. The possible role of these saponins in plant-microbe interactions is discussed...
Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulatorsElisa Barile
DISTAAM, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
Org Biomol Chem 6:1756-62. 2008....
Biogenetical related highly oxygenated macrocyclic diterpenes from sea spurge Euphorbia paraliasElisa Barile
Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
Org Lett 9:3603-6. 2007..The stereostructure elucidation of the isolated metabolites was determined by extensive spectroscopic analysis, including 1D and 2D NMR (COSY, TOCSY, HSQC, HMBC, and ROESY) and HRFABMS experiments...
Paraliane and pepluane diterpenes as anti-inflammatory agents: first insights in structure-activity relationshipsElisa Barile
DISTAAM, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
Bioorg Med Chem Lett 17:4196-200. 2007..The data obtained provided first insights towards the structure-activity relationship of this class of compounds highlighting the key role of D-ring structure...
Saponins of Allium elburzenseElisa Barile
Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, , Via F. De Sanctis, 86100 Campobasso, Italy
J Nat Prod 67:2037-42. 2004..The reported compounds have been isolated in large amounts, and this makes A. elburzense a prolific producer of saponins of the furostanol and spirostanol types...
Antispasmodic saponins from bulbs of red onion, Allium cepa L. var. TropeaGabriella Corea
Dipartimento di Chimica delle Sostanze Naturali, , Via D. Montesano 49, I-80131 Napoli, Italy
J Agric Food Chem 53:935-40. 2005..The new saponins were found to possess antispasmodic activity in the guinea pig isolated ileum; such an effect might contribute to explaining the traditional use of onion in the treatment of disturbances of the gastrointestinal tract...
Chemical composition of shallot (Allium ascalonicum Hort.)Ernesto Fattorusso
Dipartimento di Chimica delle Sostanze Naturali, , Via D. Montesano 49, Italy
J Agric Food Chem 50:5686-90. 2002..This is the first report of furostanol saponins in A. ascalonicum. High concentrations of quercetin, isorhamnetin, and their glycosides were also isolated and described...
Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activityGabriella Corea
Dipartimento di Chimica delle Sostanze Naturali, , Via D. Montesano 49, 80131 Napoli, Italy
Bioorg Med Chem 12:4909-15. 2004..The isolated compounds showed antiproliferative effect in KiMol, a transformed thyroid cell line...
Fungitoxic phenols from carnation (Dianthus caryophyllus) effective against Fusarium oxysporum f. sp. dianthiPaolo Curir
Istituto Sperimentale Floricoltura, Corso Inglesi 508, 18038 Sanremo, Italy
Phytochem Anal 14:8-12. 2003..The latter compound exhibited an appreciable fungitoxic activity towards F. oxysporum f. sp. dianthi...
Purification and properties of a new S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase from carnation (Dianthus caryophyllus L.)Paolo Curir
Istituto Sperimentale per la Floricoltura, Corso Inglesi 508, Sanremo, Italy
Eur J Biochem 270:3422-31. 2003....
Modified jatrophane diterpenes as modulators of multidrug resistance from Euphorbia dendroides LGabriella Corea
Dipartimento di Chimica delle Sostanze Naturali, , Via D. Montesano 49, I-80131, Napoli, Italy
Bioorg Med Chem 11:5221-7. 2003....
The sapogenin atroviolacegenin and its diglycoside atroviolaceoside from Allium atroviolaceumBehzad Zolfaghari
Department of Pharmacognosy, Isfahan University of Medical Sciences, Hezar Jerib Avenue, 73461 Isfahan, Iran
J Nat Prod 69:191-5. 2006..The absence of activity for both atroviolacegenin and atroviolaceoside highlighted the key role of the furostanol-type aglycone moiety for antispasmodic activity...
Saponins and flavonoids of Allium triquetrumGabriella Corea
Dipartimento di Chimica delle Sostanze Naturali, , Via D. Montesano 49, I-80131 Napoli, Italy
J Nat Prod 66:1405-11. 2003..Large amounts of seven kaempferol glycosides, of which one (7) has a new structure, were also isolated from both flowers and bulbs. The structures of the new compounds were determined by spectral and chemical methods...
Structure-activity relationships for saponins from Allium hirtifolium and Allium elburzense and their antispasmodic activityElisa Barile
DISTAAM, , Campobasso, Italy
Planta Med 71:1010-8. 2005..The observed effect therefore contributes to the explanation of the traditional use of onion and garlic in the treatment of disturbances of the gastrointestinal tract...
Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agentGabriella Corea
Dipartimento di Chimica delle Sostanze Naturali, , Via D. Montesano 49, 80131 Naples, Italy
J Med Chem 48:7055-62. 2005....
Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin AGabriella Corea
Dipartimento di Chimica delle Sostanze Naturali, , Via D. Montesano 49, I-80131 Napoli, Italy
J Med Chem 47:988-92. 2004..The most potent compound of the series, pepluanin A, showed a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport...
Structure-activity relationships for euphocharacins A-L, a new series of jatrophane diterpenes, as inhibitors of cancer cell P-glycoproteinGabriella Corea
Dipartimento di Chimica delle Sostanze Naturali, , Naples, Italy
Planta Med 70:657-65. 2004..Among the tested compounds, euphocharacins C and I showed an activity higher than cyclosporin to inhibit Pgp-mediated daunomycin transport...
Quantification of major flavonoids in carnation tissues (Dianthus caryophyllus) as a tool for cultivar discriminationFrancesco Galeotti
CRA Istituto Sperimentale per la Floricoltura, Corso Inglesi 508, 18038 Sanremo, Imperia, Italy
Z Naturforsch C 63:161-8. 2008..The presented method could be an easy, inexpensive and reliable tool for carnation cultivar discrimination...
