Virginia Lanzotti

Summary

Affiliation: University of Molise
Country: Italy

Publications

  1. ncbi The analysis of onion and garlic
    Virginia Lanzotti
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    J Chromatogr A 1112:3-22. 2006
  2. ncbi Antimicrobial furostanol saponins from the seeds of Capsicum annuum L. var. acuminatum
    Maria Iorizzi
    Dipartimento di Scienze e Tecnologie Agro alimentari, Ambientali e Microbiologiche, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    J Agric Food Chem 50:4310-6. 2002
  3. ncbi Saponins from Allium minutiflorum with antifungal activity
    Elisa Barile
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
    Phytochemistry 68:596-603. 2007
  4. doi Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators
    Elisa Barile
    DISTAAM, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    Org Biomol Chem 6:1756-62. 2008
  5. ncbi Biogenetical related highly oxygenated macrocyclic diterpenes from sea spurge Euphorbia paralias
    Elisa Barile
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
    Org Lett 9:3603-6. 2007
  6. ncbi Paraliane and pepluane diterpenes as anti-inflammatory agents: first insights in structure-activity relationships
    Elisa Barile
    DISTAAM, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    Bioorg Med Chem Lett 17:4196-200. 2007
  7. ncbi Saponins of Allium elburzense
    Elisa Barile
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
    J Nat Prod 67:2037-42. 2004
  8. ncbi Antispasmodic saponins from bulbs of red onion, Allium cepa L. var. Tropea
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, I 80131 Napoli, Italy
    J Agric Food Chem 53:935-40. 2005
  9. ncbi Chemical composition of shallot (Allium ascalonicum Hort.)
    Ernesto Fattorusso
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, Italy
    J Agric Food Chem 50:5686-90. 2002
  10. ncbi Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activity
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, 80131 Napoli, Italy
    Bioorg Med Chem 12:4909-15. 2004

Collaborators

  • Ernesto Fattorusso
  • A A Izzo
  • Raffaele Capasso
  • M Iorizzi
  • Giovanni Appendino
  • Elisa Barile
  • Gabriella Corea
  • Behzad Zolfaghari
  • Paolo Curir
  • S Ebrahim Sajjadi
  • Attilio Di Pietro
  • Marcello Dolci
  • Pierre Noël Simon
  • Charles Dumontet
  • Francesco Galeotti
  • Armando Ialenti
  • Angela Ianaro
  • Riccardo Motti
  • Paola Dolci
  • Marianna Borriello
  • Caterina Fattorusso
  • Agnes Doreau
  • Felice Scala
  • Giuliano Bonanomi
  • Vincenzo Antignani
  • Pasquale Maffia
  • Paola Di Meglio
  • Gianluca Grassia
  • Maria Cammareri
  • Clara Conicella
  • Maurizio Bifulco
  • Chiara Laezza
  • Gordon Tollin
  • Orazio Taglialatela-Scafati
  • Mauro Ballero
  • Carlo Pasini
  • Luc De Cooman

Detail Information

Publications20

  1. ncbi The analysis of onion and garlic
    Virginia Lanzotti
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    J Chromatogr A 1112:3-22. 2006
    ..Particular attention was given to the different methodology developed to perform chemical analysis, including separation and structural elucidation...
  2. ncbi Antimicrobial furostanol saponins from the seeds of Capsicum annuum L. var. acuminatum
    Maria Iorizzi
    Dipartimento di Scienze e Tecnologie Agro alimentari, Ambientali e Microbiologiche, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    J Agric Food Chem 50:4310-6. 2002
    ..Data indicated that the antiyeast activity was related to the combination of the oligosaccharide chain (S1, S2, or S3) with an O-methyl group at R(3) and the presence of a hydroxyl group at the C-2 position...
  3. ncbi Saponins from Allium minutiflorum with antifungal activity
    Elisa Barile
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
    Phytochemistry 68:596-603. 2007
    ..No appreciable antibacterial activity was recorded. The possible role of these saponins in plant-microbe interactions is discussed...
  4. doi Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators
    Elisa Barile
    DISTAAM, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    Org Biomol Chem 6:1756-62. 2008
    ....
  5. ncbi Biogenetical related highly oxygenated macrocyclic diterpenes from sea spurge Euphorbia paralias
    Elisa Barile
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
    Org Lett 9:3603-6. 2007
    ..The stereostructure elucidation of the isolated metabolites was determined by extensive spectroscopic analysis, including 1D and 2D NMR (COSY, TOCSY, HSQC, HMBC, and ROESY) and HRFABMS experiments...
  6. ncbi Paraliane and pepluane diterpenes as anti-inflammatory agents: first insights in structure-activity relationships
    Elisa Barile
    DISTAAM, Università degli Studi del Molise, Via F De Sanctis, I 86100 Campobasso, Italy
    Bioorg Med Chem Lett 17:4196-200. 2007
    ..The data obtained provided first insights towards the structure-activity relationship of this class of compounds highlighting the key role of D-ring structure...
  7. ncbi Saponins of Allium elburzense
    Elisa Barile
    Dipartimento di Scienze e Tecnologie Agroalimentari, Ambientali e Microbiologiche, Universita del Molise, Via F De Sanctis, 86100 Campobasso, Italy
    J Nat Prod 67:2037-42. 2004
    ..The reported compounds have been isolated in large amounts, and this makes A. elburzense a prolific producer of saponins of the furostanol and spirostanol types...
  8. ncbi Antispasmodic saponins from bulbs of red onion, Allium cepa L. var. Tropea
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, I 80131 Napoli, Italy
    J Agric Food Chem 53:935-40. 2005
    ..The new saponins were found to possess antispasmodic activity in the guinea pig isolated ileum; such an effect might contribute to explaining the traditional use of onion in the treatment of disturbances of the gastrointestinal tract...
  9. ncbi Chemical composition of shallot (Allium ascalonicum Hort.)
    Ernesto Fattorusso
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, Italy
    J Agric Food Chem 50:5686-90. 2002
    ..This is the first report of furostanol saponins in A. ascalonicum. High concentrations of quercetin, isorhamnetin, and their glycosides were also isolated and described...
  10. ncbi Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activity
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, 80131 Napoli, Italy
    Bioorg Med Chem 12:4909-15. 2004
    ..The isolated compounds showed antiproliferative effect in KiMol, a transformed thyroid cell line...
  11. ncbi Fungitoxic phenols from carnation (Dianthus caryophyllus) effective against Fusarium oxysporum f. sp. dianthi
    Paolo Curir
    Istituto Sperimentale Floricoltura, Corso Inglesi 508, 18038 Sanremo, Italy
    Phytochem Anal 14:8-12. 2003
    ..The latter compound exhibited an appreciable fungitoxic activity towards F. oxysporum f. sp. dianthi...
  12. ncbi Purification and properties of a new S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase from carnation (Dianthus caryophyllus L.)
    Paolo Curir
    Istituto Sperimentale per la Floricoltura, Corso Inglesi 508, Sanremo, Italy
    Eur J Biochem 270:3422-31. 2003
    ....
  13. ncbi Modified jatrophane diterpenes as modulators of multidrug resistance from Euphorbia dendroides L
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, I 80131, Napoli, Italy
    Bioorg Med Chem 11:5221-7. 2003
    ....
  14. ncbi The sapogenin atroviolacegenin and its diglycoside atroviolaceoside from Allium atroviolaceum
    Behzad Zolfaghari
    Department of Pharmacognosy, Isfahan University of Medical Sciences, Hezar Jerib Avenue, 73461 Isfahan, Iran
    J Nat Prod 69:191-5. 2006
    ..The absence of activity for both atroviolacegenin and atroviolaceoside highlighted the key role of the furostanol-type aglycone moiety for antispasmodic activity...
  15. ncbi Saponins and flavonoids of Allium triquetrum
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, I 80131 Napoli, Italy
    J Nat Prod 66:1405-11. 2003
    ..Large amounts of seven kaempferol glycosides, of which one (7) has a new structure, were also isolated from both flowers and bulbs. The structures of the new compounds were determined by spectral and chemical methods...
  16. ncbi Structure-activity relationships for saponins from Allium hirtifolium and Allium elburzense and their antispasmodic activity
    Elisa Barile
    DISTAAM, Università degli Studi del Molise, Campobasso, Italy
    Planta Med 71:1010-8. 2005
    ..The observed effect therefore contributes to the explanation of the traditional use of onion and garlic in the treatment of disturbances of the gastrointestinal tract...
  17. ncbi Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, 80131 Naples, Italy
    J Med Chem 48:7055-62. 2005
    ....
  18. ncbi Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin A
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, via D Montesano 49, I 80131 Napoli, Italy
    J Med Chem 47:988-92. 2004
    ..The most potent compound of the series, pepluanin A, showed a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport...
  19. ncbi Structure-activity relationships for euphocharacins A-L, a new series of jatrophane diterpenes, as inhibitors of cancer cell P-glycoprotein
    Gabriella Corea
    Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, Naples, Italy
    Planta Med 70:657-65. 2004
    ..Among the tested compounds, euphocharacins C and I showed an activity higher than cyclosporin to inhibit Pgp-mediated daunomycin transport...
  20. ncbi Quantification of major flavonoids in carnation tissues (Dianthus caryophyllus) as a tool for cultivar discrimination
    Francesco Galeotti
    CRA Istituto Sperimentale per la Floricoltura, Corso Inglesi 508, 18038 Sanremo, Imperia, Italy
    Z Naturforsch C 63:161-8. 2008
    ..The presented method could be an easy, inexpensive and reliable tool for carnation cultivar discrimination...