Paolo Landini

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Cross-talk mechanisms in biofilm formation and responses to environmental and physiological stress in Escherichia coli
    Paolo Landini
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Via Celoria 22, 20133 Milan, Italy
    Res Microbiol 160:259-66. 2009
  2. pmc In vitro transcription profiling of the σS subunit of bacterial RNA polymerase: re-definition of the σS regulon and identification of σS-specific promoter sequence elements
    Anna Maciag
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    Nucleic Acids Res 39:5338-55. 2011
  3. pmc The pyrimidine nucleotide biosynthetic pathway modulates production of biofilm determinants in Escherichia coli
    Marco Garavaglia
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    PLoS ONE 7:e31252. 2012
  4. doi request reprint Molecular mechanisms of compounds affecting bacterial biofilm formation and dispersal
    Paolo Landini
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    Appl Microbiol Biotechnol 86:813-23. 2010
  5. ncbi request reprint The yddV-dos operon controls biofilm formation through the regulation of genes encoding curli fibers' subunits in aerobically growing Escherichia coli
    Letizia Tagliabue
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Milan, Italy
    FEMS Immunol Med Microbiol 59:477-84. 2010
  6. doi request reprint Cellulose modulates biofilm formation by counteracting curli-mediated colonization of solid surfaces in Escherichia coli
    Luciana Gualdi
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Via Celoria 26, 20133 Milan, Italy
    Microbiology 154:2017-24. 2008
  7. doi request reprint The diguanylate cyclase YddV controls production of the exopolysaccharide poly-N-acetylglucosamine (PNAG) through regulation of the PNAG biosynthetic pgaABCD operon
    Letizia Tagliabue
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Via Celoria 26, 20133 Milan, Italy
    Microbiology 156:2901-11. 2010
  8. doi request reprint The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
    Davide Antoniani
    Department of Biosciences, Universita degli Studi di Milano, Via Celoria 26, 20133 Milan, Italy
    Appl Microbiol Biotechnol 97:7325-36. 2013
  9. doi request reprint Monitoring of diguanylate cyclase activity and of cyclic-di-GMP biosynthesis by whole-cell assays suitable for high-throughput screening of biofilm inhibitors
    Davide Antoniani
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    Appl Microbiol Biotechnol 85:1095-104. 2010
  10. pmc Biofilm formation-gene expression relay system in Escherichia coli: modulation of sigmaS-dependent gene expression by the CsgD regulatory protein via sigmaS protein stabilization
    Luciana Gualdi
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Via Celoria 26, 20133 Milan, Italy
    J Bacteriol 189:8034-43. 2007

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Cross-talk mechanisms in biofilm formation and responses to environmental and physiological stress in Escherichia coli
    Paolo Landini
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Via Celoria 22, 20133 Milan, Italy
    Res Microbiol 160:259-66. 2009
    ..Regulatory mechanisms of this process include two-component regulatory systems, master regulators such as the rpoS gene and signal molecules such as cyclic-di-GMP, in a tight and complex interplay...
  2. pmc In vitro transcription profiling of the σS subunit of bacterial RNA polymerase: re-definition of the σS regulon and identification of σS-specific promoter sequence elements
    Anna Maciag
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    Nucleic Acids Res 39:5338-55. 2011
    ..Indeed, site-directed mutagenesis experiments confirmed that an A/T bias in the -10/+1 region could improve promoter recognition by Eσ(S)...
  3. pmc The pyrimidine nucleotide biosynthetic pathway modulates production of biofilm determinants in Escherichia coli
    Marco Garavaglia
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    PLoS ONE 7:e31252. 2012
    ....
  4. doi request reprint Molecular mechanisms of compounds affecting bacterial biofilm formation and dispersal
    Paolo Landini
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    Appl Microbiol Biotechnol 86:813-23. 2010
    ..Finally, we discuss the activation of biofilm dispersal as a novel mode of action for anti-biofilm compounds...
  5. ncbi request reprint The yddV-dos operon controls biofilm formation through the regulation of genes encoding curli fibers' subunits in aerobically growing Escherichia coli
    Letizia Tagliabue
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Milan, Italy
    FEMS Immunol Med Microbiol 59:477-84. 2010
    ..coli, and suggest that YddV and Dos, through their opposite activities, might finely tune curli production in response to oxygen availability...
  6. doi request reprint Cellulose modulates biofilm formation by counteracting curli-mediated colonization of solid surfaces in Escherichia coli
    Luciana Gualdi
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Via Celoria 26, 20133 Milan, Italy
    Microbiology 154:2017-24. 2008
    ..coli MG1655...
  7. doi request reprint The diguanylate cyclase YddV controls production of the exopolysaccharide poly-N-acetylglucosamine (PNAG) through regulation of the PNAG biosynthetic pgaABCD operon
    Letizia Tagliabue
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Via Celoria 26, 20133 Milan, Italy
    Microbiology 156:2901-11. 2010
    ..coli, c-di-GMP biosynthesis by a given DGC protein triggers regulatory events that lead to activation of specific sets of EPS biosynthetic genes or proteins...
  8. doi request reprint The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
    Davide Antoniani
    Department of Biosciences, Universita degli Studi di Milano, Via Celoria 26, 20133 Milan, Italy
    Appl Microbiol Biotechnol 97:7325-36. 2013
    ..Our results indicate that azathioprine can prevent biofilm formation in E. coli through inhibition of c-di-GMP biosynthesis and suggest that such inhibition might contribute to its anti-inflammatory activity in Crohn's disease. ..
  9. doi request reprint Monitoring of diguanylate cyclase activity and of cyclic-di-GMP biosynthesis by whole-cell assays suitable for high-throughput screening of biofilm inhibitors
    Davide Antoniani
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milan, Italy
    Appl Microbiol Biotechnol 85:1095-104. 2010
    ....
  10. pmc Biofilm formation-gene expression relay system in Escherichia coli: modulation of sigmaS-dependent gene expression by the CsgD regulatory protein via sigmaS protein stabilization
    Luciana Gualdi
    Department of Biomolecular Sciences and Biotechnology, University of Milan, Via Celoria 26, 20133 Milan, Italy
    J Bacteriol 189:8034-43. 2007
    ..Direct coordination between biofilm formation and expression of the rpoS regulon could positively impact important biological processes, such as host colonization or response to environmental stresses...
  11. pmc An efficient rRNA removal method for RNA sequencing in GC-rich bacteria
    Clelia Peano
    Institute of Biomedical Technologies, National Research Council, Segrate, Milan, Italy
    Microb Inform Exp 3:1. 2013
    ..abstract:..
  12. pmc Growth in glucose-based medium and exposure to subinhibitory concentrations of imipenem induce biofilm formation in a multidrug-resistant clinical isolate of Acinetobacter baumannii
    Elisabetta Nucleo
    Department of Biomolecular Sciences and Biotechnology, Universita degli Studi di Milano, Milano, Italy
    BMC Microbiol 9:270. 2009
    ..Acinetobacter baumannii is emerging as an important nosocomial pathogen. Multidrug resistance, as well as ability to withstand environmental stresses, makes eradication of A. baumannii difficult, particularly from hospital settings...
  13. pmc The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-N-acetylglucosamine (PNAG) production in Escherichia coli C
    Thomas Carzaniga
    Department of Biosciences, University of Milan, Via Celoria 26, Milan, 20133, Italy
    BMC Microbiol 12:270. 2012
    ....
  14. ncbi request reprint Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis
    Clelia Peano
    Institute of Biomedical Technologies, National Research Council, Segrate, Milan, Italy
    PLoS ONE 9:e93009. 2014
    ..thailandensis cell motility, oxygen limitation has a deeper impact on its physiology and constitutes a crucial environmental signal for the production of virulence factors. ..
  15. doi request reprint Effects of chronic sub-lethal oxidative stress on biofilm formation by Azotobacter vinelandii
    Federica Villa
    Dipartimento di Scienze per gli Alimenti, la Nutrizione e l Ambiente, Universita degli Studi di Milano, Via Celoria 2, Milano, 20133, Italy
    Biofouling 28:823-33. 2012
    ..A continuous exogenous source of ROS increased biofilm formation in UW136. Overall, chronic sub-lethal oxidative events promoted sessile behavior in A. vinelandii...
  16. doi request reprint sigmaS, a major player in the response to environmental stresses in Escherichia coli: role, regulation and mechanisms of promoter recognition
    Paolo Landini
    Department of Biosciences, Universita degli Studi di Milano, Via Celoria 26, 20133, Milan, Italy
    Environ Microbiol Rep 6:1-13. 2014
    ..In this report, we discuss the function of the rpoS gene in the general stress response, and review the current knowledge on regulation of rpoS expression and on promoter recognition by σ(S). ..