Emmanuele A Jannini

..On the other hand, social theorists, without direct evidence confirming their positions, criticize, with good argument, methods and results of the other side. The aim of this Controversy is to understand the reasons of both perspectives...

..Accumulating evidence suggests that premature ejaculation is the most common sexual symptom. This review focuses on the epidemiology of premature ejaculation from geographical and medical perspectives...

..This opinion is now rejected, and intercourse is generally considered healthy. However, while some aspects of the equation "more sex equals more health" have been demonstrated, others still need robust data for confirmation...

..No controversy can be more controversial than that regarding the existence of the G-spot, an anatomical and physiological entity for women and many scientists, yet a gynecological UFO for others...

..Sexual health care professionals (SHCP) may face several ethical issues. Some SHCP prescribe Internet pornography for both diagnosis and therapy and some others directly sell vibrators and sex aids in their offices...

..There is general agreement that it is possible to have an orgasm thru the direct simulation of the external clitoris. In contrast, the possibility of achieving climax during penetration has been controversial...

..Several methods have been so far proposed to compare the effectiveness of the three available phosphodiesterase type 5 inhibitors (PDE5Is)...

..The aim of this Controversy is to discuss if this philosophy is still useful both in the conceptual and clinical perspective...

..The aim of this Controversy is to appreciate opinions from both perspectives...

..Furthermore, currently adequately powered and optimally designed long-term prostate disease data are not available to determine if there is an additional risk from normal T values in cured patients for PCa...

..It is controversial whether or not the most frequent male sexual dysfunctions, premature ejaculation (PE) and erectile dysfunction (ED), share pathogenetic mechanisms and treatments...

..Although there are pharmacological differences between these three compounds, few comparative studies have been conducted to date...

..Our findings provide evidence that belinostat may be a promising anticancer drug for prostate cancer expressing AR, supporting its clinical role in prostate cancer...

..The mechanisms controlling erection in animals and in humans are mainly age-dependent. However, the ontogenesis of the biochemical machinery of erection is largely unknown...

..The physiology and anatomy of female sexual function are poorly understood. The differences in sexual function among women may be partly attributed to anatomical factors...

..Our findings provide evidence of a relationship between the castration-resistant phenotype and DNMT expression and activity in human prostate cancer...

..Our results provide a rationale for combinatorial treatment using conventional chemotherapy and a Akt/mTOR inhibitor as promising therapeutic approach for the treatment of HRPC, a disease largely resistant to conventional therapies...

..We measured premature ejaculation related female sexual distress using a new diagnostic tool, the Female Sexual Distress Scale-Revised-Premature Ejaculation questionnaire...

..In addition, we suggest research into biochemical markers to define this condition, which we have named subclinical erectile dysfunction...

..In the last few years, various studies have underlined a correlation between thyroid function and male sexual function, hypothesizing a direct action of thyroid hormones on the penis...

..Our data demonstrate that GLUT1 and GLUT8 are both expressed in prepubertal testis, but only GLUT1 is regulated by T(3). In addition, we found that the effect of T(3) cannot be attributed to its action on GLUT1 promoter...

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..This study tested the hypothesis that 5-Aza may restore and enhance the responsiveness of HRPC cells to anti-hormonal therapy on Androgen receptor (AR) expressing (22rv1) and AR-deficient (PC3) cells...

..The frequency and the clinical characteristics of erectile dysfunction (ED) and premature ejaculation (PE) in infertile men have been poorly investigated...

..Because diagnosis informs treatment decisions that have an impact on clinical outcomes, the ability to diagnose PE accurately is vital to the successful management of this condition...

..This will soon demolish the barriers to seeking help perceived by patients suffering ejaculatory disorders...

..Shall we continue to consider these tools as a diagnostic gold standard in ED diagnosis?..

..New treatments and more effective drugs are expected in the near future because of the rapid expansion of research into erection regulation mechanisms and epidemiological studies...