Research Topics
| E A JanniniSummaryAffiliation: University of L'Aquila Country: Italy Publications
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Detail Information
Publications
Epidemiology of premature ejaculationEmmanuele A Jannini
Course of Medical Sexology and Endocrinology, Department of Experimental Medicine, University of L Aquila, Italy
Curr Opin Urol 15:399-403. 2005..Accumulating evidence suggests that premature ejaculation is the most common sexual symptom. This review focuses on the epidemiology of premature ejaculation from geographical and medical perspectives...
Psychosocial issues of ART in aging maleE Carosa
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
J Endocrinol Invest 28:117-21. 2005....
Ejaculatory disorders: epidemiology and current approaches to definition, classification and subtypingEmmanuele A Jannini
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, Coppito, Bldg 2, Room A2 54, 67100 L Aquila, Italy
World J Urol 23:68-75. 2005..This will soon demolish the barriers to seeking help perceived by patients suffering ejaculatory disorders...
Evaluation of premature ejaculationEmmanuele A Jannini
Department of Experimental Medicine, School of Sexology, University of L Aquila, L Aquila, Italy
J Sex Med 8:328-34. 2011..Because diagnosis informs treatment decisions that have an impact on clinical outcomes, the ability to diagnose PE accurately is vital to the successful management of this condition...
Use and abuse of Rigiscan in the diagnosis of erectile dysfunctionEmmanuele A Jannini
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
J Sex Med 6:1820-9. 2009..Shall we continue to consider these tools as a diagnostic gold standard in ED diagnosis?..
Introduction to the integrated model: medical, surgical and psychological therapies for the coupleE A Jannini
Course of Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
J Endocrinol Invest 26:128-31. 2003..Considering the growing complexity of therapies for sexual symptoms and diseases, there seems to be a need for the new professional figure of the medical sexologist...
Correlation between ejaculatory and erectile dysfunctionE A Jannini
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, Coppito, Bldg 2, Room A2 54 Via Vetoio, 67100 L Aquila, Rome, Italy
Int J Androl 28:40-5. 2005..Finally, erectile dysfunctions (ED) and ejaculatory dysfunctions frequently overlap. The aim of this review article is to propose a new taxonomy of PE, which considers ED as an important factor of PE and vice versa...
Disorders of ejaculationE A Jannini
Department of Experimental Medicine of the University of L Aquila, L Aquila, Italy
J Endocrinol Invest 25:1006-19. 2002..Rarer disorders are emission and ejaculation failure and urine contamination of semen. The new use of diagnostic procedures and the availability of pharmacological aids place this topic in the mainframe of medical sexology...
Sexological approach to ejaculatory dysfunctionE A Jannini
Course of Medical Sexology, Department of Experimental Medicine, University of L Aquila, Italy
Int J Androl 25:317-23. 2002....
Might erectile dysfunction be due to the thermolabile variant of methylenetetrahydrofolate reductase?F Lombardo
Unit of Seminology and Immunology of Reproduction, Department of Medical Physiopathology, University of Rome La Sapienza, Rome, Italy
J Endocrinol Invest 27:883-5. 2004..Furthermore, careful attention should be given to the risk of ED when dealing with this metabolic disturbance...
Androgens and fertilityF Lombardo
Department of Medical Pathophysiology, 1st University of Rome La Sapienza, Rome, Italy
J Endocrinol Invest 28:51-5. 2005..Abuse of anabolic steroids is a frequent cause of male infertility, and substances such as endocrine disruptors can alter male fertility through an anti androgenic action...
Diagnosing erectile dysfunction: instruments for endocrine diagnosisF Lombardo
Department of Medical Pathophysiology, Laboratory of Seminology and Immunology of Reproduction, Policlinico Umberto I, 1st University of Rome La Sapienza, Rome, Italy
Int J Androl 28:53-5. 2005....
The therapeutic dilemma: how to use tadalafilE Carosa
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L'Aquila 67100 L'Aquila, Italy
Int J Androl 28:74-80. 2005..It has unique pharmacokinetic properties in its drug class, which also includes sildenafil and vardenafil. It is also well tolerated with few side-effects, and can be used in difficult patients such as neuropaths or diabetics...
[Ageing and male sexuality]E A Jannini
Dipartimento di Medicina Sperimentale, Universita dell Aquila, 67100 L Aquila, Italy
Minerva Ginecol 59:35-41. 2007..The challenge to the clinical sexologist, therefore, is to identify appropriate treatment approaches for an ageing population with an increasingly longer life expectancy and the right to a sexually satisfying life...
Prevalence of chronic prostatitis in men with premature ejaculationE Screponi
Division of Medicine of Reproduction and Sexology, Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy
Urology 58:198-202. 2001....
Stress, sexual dysfunctions, and male infertilityA Lenzi
Department of Medical Physiopathology, 1st University of Rome La Sapienza, Rome, Italy
J Endocrinol Invest 26:72-6. 2003....
The ENDOTRIAL study: a spontaneous, open-label, randomized, multicenter, crossover study on the efficacy of sildenafil, tadalafil, and vardenafil in the treatment of erectile dysfunctionEmmanuele A Jannini
School of Sexology, Department of Experimental Medicine, University of L Aquila, Coppito, L Aquila, Italy
J Sex Med 6:2547-60. 2009..Although there are pharmacological differences between these three compounds, few comparative studies have been conducted to date...
Clinical and basic science research in sexual medicine must rely, in part, on pharmaceutical funding?Emmanuele A Jannini
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
J Sex Med 7:2331-7. 2010..The aim of this Controversy is to appreciate opinions from both perspectives...
Is sex just fun? How sexual activity improves healthEmmanuele A Jannini
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila 67100, Italy
J Sex Med 6:2640-8. 2009..This opinion is now rejected, and intercourse is generally considered healthy. However, while some aspects of the equation "more sex equals more health" have been demonstrated, others still need robust data for confirmation...
Male homosexuality: nature or culture?Emmanuele A Jannini
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
J Sex Med 7:3245-53. 2010..On the other hand, social theorists, without direct evidence confirming their positions, criticize, with good argument, methods and results of the other side. The aim of this Controversy is to understand the reasons of both perspectives...
Organic vs. psychogenic? The Manichean diagnosis in sexual medicineEmmanuele A Jannini
Course of Endocrinology and Medical Sexology, University of L Aquila, L Aquila, Italy
J Sex Med 7:1726-33. 2010..The aim of this Controversy is to discuss if this philosophy is still useful both in the conceptual and clinical perspective...
Who's afraid of the G-spot?Emmanuele A Jannini
Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, Italy
J Sex Med 7:25-34. 2010..No controversy can be more controversial than that regarding the existence of the G-spot, an anatomical and physiological entity for women and many scientists, yet a gynecological UFO for others...
Type 5 phosphodiesterase expression in the human vaginaCira R T di Gioia
Department of Experimental Medicine and Pathology, University of Rome La Sapienza, Rome, Italy
Urology 60:191-5. 2002....
Functional anatomy of the human vaginaC R T di Gioia
Department of Experimental Medicine and Pathology, 1st University of Rome, La Sapienza, Rome, Italy
J Endocrinol Invest 26:92-6. 2003..However, it is now apparent that modern sexology cannot be truly 'medical' if female sexual anatomy and the physiology of female sexual response are unknown...
Sexual inactivity results in reversible reduction of LH bioavailabilityE Carosa
Division of Endocrinology and Reproductive Medicine, Department of Experimental Medicine, University of L'Aquila, Italy
Int J Impot Res 14:93-9; discussion 100. 2002..Because biopotency of pituitary hormones is controlled by the hypothalamus, LH hypoactivity should be due to the hypothalamic functional damage associated to the psychological disturbances which unavoidably follow sexual inactivity...
Endocrinological diagnosis in sexologyF Lombardo
University Laboratory of Seminology and Immunology of Reproduction, Department of Medical Pathophysiology, 1st University of Rome La Sapienza, Rome, Italy
J Endocrinol Invest 26:112-4. 2003..It is therefore necessary that the diagnostic process for sexual dysfunctions of an endocrine nature be as integrated and wide as possible, especially as such pathologies are usually extremely responsive to medical or surgical therapy...
Type V phosphodiesterase inhibitor treatments for erectile dysfunction increase testosterone levelsEleonora Carosa
Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy
Clin Endocrinol (Oxf) 61:382-6. 2004....
Transdermal electromotive administration of verapamil and dexamethasone for Peyronie's diseaseS M Di Stasi
Department of Urology, Tor Vergata University, Rome, Italy
BJU Int 91:825-9. 2003..To evaluate the effects of the transdermal electromotive administration of verapamil and dexamethasone on plaque size, penile deviation, pain, erectile function and capacity for vaginal penetration in patients with Peyronie's disease...
Subclinical erectile dysfunction: proposal for a novel taxonomic category in sexual medicineEmmanuele A Jannini
Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
J Sex Med 3:787-93; discussion 794. 2006..In addition, we suggest research into biochemical markers to define this condition, which we have named subclinical erectile dysfunction...
Development and validation of a 6-item version of the female sexual function index (FSFI) as a diagnostic tool for female sexual dysfunctionAndrea M Isidori
Department of Medical Pathophysiology, University of Rome La Sapienza, Rome, Italy
J Sex Med 7:1139-46. 2010..Often, practitioners avoid investigating sexual symptoms due to concerns of insufficient time or lack of proper tools to address FSD...
Measurement of the thickness of the urethrovaginal space in women with or without vaginal orgasmGiovanni Luca Gravina
Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
J Sex Med 5:610-8. 2008..The physiology and anatomy of female sexual function are poorly understood. The differences in sexual function among women may be partly attributed to anatomical factors...
5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumorsGiovanni Luca Gravina
Division of Radiotherapy, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
Prostate 70:1166-78. 2010..This study tested the hypothesis that 5-Aza may restore and enhance the responsiveness of HRPC cells to anti-hormonal therapy on Androgen receptor (AR) expressing (22rv1) and AR-deficient (PC3) cells...
Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropinAlessia Belmonte
Department of Surgery, University Tor Vergata, Rome, Italy
J Soc Gynecol Investig 12:570-7. 2005..CONCLUSIONS: PDE5 protein is expressed in human non-pregnant and pregnant myometrium. HCG reduces PDE5 expression and enzyme activity in smooth muscle cells, possibly through a pathway involving cAMP...
New perspectives in the pharmacotherapy of erectile dysfunctionEmmanuele A Jannini
Department of Experimental Medicine, Course of Medical Sexology, University of L'Aquila, 67100 L'Aquila, Italy
IDrugs 6:1165-72. 2003..New treatments and more effective drugs are expected in the near future because of the rapid expansion of research into erection regulation mechanisms and epidemiological studies...
Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patientsCesare Carani
Department of Endocrinology, University of Modena, Italy
J Clin Endocrinol Metab 90:6472-9. 2005..Despite the associated changes in sex hormone levels, the high prevalence of ejaculatory disorders and their prompt reversibility suggest a direct involvement of thyroid hormones in the physiology of ejaculation...
Editorial comment on: Relation between the Saint Louis University ADAM questionnaire and sexual hormonal levels in a male outpatient population over 50 years of ageEmmanuele A Jannini
Eur Urol 52:1766-7. 2007
Treatment of sexual dysfunctions secondary to male infertility with sildenafil citrateEmmanuele A Jannini
Fertil Steril 81:705-7. 2004..Two pregnancies were obtained after sildenafil administration...
Sexual symptoms in endocrine diseases: psychosomatic perspectivesGiancarlo Balercia
Endocrinology, Andrology Unit, Department of Clinical Medicine and Applied Biotechnologies, Polytechnic University of Marche, Ancona, Italy
Psychother Psychosom 76:134-40. 2007..may have a greater or lesser effect on sexual function...
Loss of sexual desire in the postmenopausal womanKevan Wylie
Porterbrook Clinic, Sheffield, UK
J Sex Med 4:395-405. 2007..Hypoactive sexual desire disorder (HSDD) is a common clinical problem that may bother women...
Possible correlation between type 1 diabetes mellitus and female sexual dysfunction: case report and literature reviewAntonella Bultrini
Course of Endocrinology and Sexual Medicine at the Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy
J Sex Med 1:337-40. 2004..It also demonstrates the need to take into account, not only in males, a sexual history in the management of diabetes mellitus...
Male reproductive physiology as a sexually selected handicap? Erectile dysfunction is correlated with general health and health prognosis and may have evolved as a marker of poor phenotypic qualityAlessandro Cellerino
Scuola Normale Superiore, Laboratorio di Neurobiologia, c o Isituto di Neuroscienze del CNR, Via Moruzzi 1, 1 56100 Ghezzano Pisa Italy
Med Hypotheses 65:179-84. 2005..We suggest that the fragility of male sexual physiology observed in modern society is the specific consequence of an evolutionary process driven by the handicap principle...
Androgens regulate phosphodiesterase type 5 expression and functional activity in corpora cavernosaAnnamaria Morelli
Andrology Unit, Department of Clinical Physiopathology, University of Florence, Florence 50139, Italy
Endocrinology 145:2253-63. 2004..In conclusion, we demonstrated, for the first time, that androgens positively regulate PDE5, thus providing a possible explanation about the highest abundance of this enzyme in male genital tract...
