Research Topics
| Maurizio InghilleriSummaryAffiliation: University of Rome La Sapienza Country: Italy Publications
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Detail Information
Publications
Altered response to rTMS in patients with Alzheimer's diseaseM Inghilleri
Department of Neurological Sciences, University of Rome La Sapienza, Viale dell Universita, 30, 00185 Rome, Italy
Clin Neurophysiol 117:103-9. 2006....
Is the cutaneous silent period an opiate-sensitive nociceptive reflex?Maurizio Inghilleri
Department of Neurological Sciences, University of Rome La Sapienza, Viale dell Universita 30, 00185 Rome, Italy
Muscle Nerve 25:695-9. 2002....
Clinical neurophysiology in ALSMaurizio Inghilleri
Department of Neurological Sciences, University of Rome Sapienza, Rome, Italy
Arch Ital Biol 149:57-63. 2011..In this chapter the advantages, limitations and promise of these various methods are discussed, in order to indicate the direction for further neurophysiological studies in this disorder...
Venlafaxine and bladder functionMaurizio Inghilleri
Department of Neurological Sciences, University of Rome La Sapienza, Viale dell Universita 30, 00185 Rome, Italy
Clin Neuropharmacol 28:270-3. 2005..Occasional case reports describe urinary incontinence in patients taking the selective serotonin and norepinephrine reuptake inhibitor antidepressant venlafaxine...
Belly dance syndrome due to spinal myoclonusMaurizio Inghilleri
Department of Neurological Sciences, University of Rome La Sapienza, Rome, Italy
Mov Disord 21:394-6. 2006..We report on a case of spinal myoclonus resembling a belly dance syndrome...
Synaptic potentiation induced by rTMS: effect of lidocaine infusionM Inghilleri
Department of Neurological Sciences, University of Rome La Sapienza, Viale dell Universita, 30, 00185 Rome, Italy
Exp Brain Res 163:114-7. 2005..Our results suggest that the MEP facilitation related to rTMS-induced synaptic potentiation results from an increase in cortical excitatory interneuron excitability that involves voltage-gated sodium channels...
Topiramate and cortical excitability in humans: a study with repetitive transcranial magnetic stimulationM Inghilleri
Dipartimento Scienze Neurologiche, Universita di Roma La Sapienza, Rome, Italy
Exp Brain Res 174:667-72. 2006....
Ovarian hormones and cortical excitability. An rTMS study in humansM Inghilleri
Department of Neurological Sciences, University of Rome La Sapienza, Viale dell Universita 30, 00185 Rome, Italy
Clin Neurophysiol 115:1063-8. 2004..Ovarian steroids influence neural excitability. Using repetitive transcranial magnetic stimulation (rTMS) we investigated changes in cortical excitability during the menstrual cycle...
Antiepileptic drugs and cortical excitability: a study with repetitive transcranial stimulationM Inghilleri
Department of Neurological Sciences, Viale dell Universita 30, 00185, Rome, Italy
Exp Brain Res 154:488-93. 2004..Our results suggest that carbamazepine, gabapentin and topiramate modulate intracortical excitability by acting selectively on excitatory interneurons...
Bilateral spike-and-wave discharges in a hemi-deafferented cortexM Inghilleri
Department of Neurological Sciences, University of Rome, Rome, Italy
Clin Neurophysiol 113:1970-2. 2002..Three days after antiepileptic treatment (sodium valproate 500mg 3 times a day) began, electroenceplalographic recordings and consciousness became normal...
Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosisAntonella Conte
Department of Neurological Sciences, University of Rome Sapienza, Viale dell Universita 30, 00185 Rome, Italy
Eur J Pain 13:472-7. 2009..In conclusion, the cannabinoid-induced changes in the RIII reflex threshold and area in patients with MS provide objective neurophysiological evidence that cannabinoids modulate the nociceptive system in patients with MS...
Influence of the corticospinal tract on the cutaneous silent period: a study in patients with pyramidal syndromeFrancesca Gilio
Department of Neurological Sciences, University of Rome Sapienza, Viale dell Universita 30, 00185 Rome, Italy
Neurosci Lett 433:109-13. 2008..None of the other variables differed in patients and healthy subjects. Our findings suggest that corticospinal projections influence the CSP latency probably by modulating the balance of excitability in the underlying circuits...
Botulinum toxin type A for the treatment of sialorrhoea in amyotrophic lateral sclerosis: a clinical and neurophysiological studyFrancesca Gilio
Department of Neurological Sciences, University of Rome Sapienza, Rome, Italy
Amyotroph Lateral Scler 11:359-63. 2010..In conclusion, intraparotid anatomically-guided BoNT/A injection is an effective, easy, and safe treatment for sialorrhoea in patients with bulbar symptoms related to ALS...
Renal aplastic dysplasia and ipsilateral ectopic ureter obstructing the seminal via: a possible cause of male infertility: Part 2Antonio Carbone
Neuro-Urology Unit, University of Rome La Sapienza Polo Pontino, Rome, Italy
Eur Urol 52:600. 2007
Renal aplastic dysplasia and ipsilateral ectopic ureter obstructing the seminal via: a possible cause of male infertility: Part 2Antonio Carbone
Neuro-Urology Unit, University of Rome La Sapienza Polo Pontino, Rome, Italy
Eur Urol 52:600-1. 2007
Riluzole blocks human muscle acetylcholine receptorsCristina Deflorio
Department of Physiology and Pharmacology, Sapienza University, Rome, Italy
J Physiol 590:2519-28. 2012....
Electrical and magnetic repetitive transcranial stimulation of the primary motor cortex in healthy subjectsFrancesca Gilio
Neurology and Neurophysiopathology Unit, S Pertini, Rome, Italy
Neurosci Lett 455:1-3. 2009..Our results suggest that 5 Hz-rTES delivered in short trains increases cortical excitability and does so by acting on the excitatory interneurones probably through mechanisms similar to those underlying the rTMS-induced MEP facilitation...
Differences in short-term primary motor cortex synaptic potentiation as assessed by repetitive transcranial magnetic stimulation in migraine patients with and without auraAntonella Conte
Department of Neurological Sciences and Neuromed Institute, Sapienza, University of Rome, Rome, Italy
Pain 148:43-8. 2010....
Effects of attention on inhibitory and facilitatory phenomena elicited by paired-pulse transcranial magnetic stimulation in healthy subjectsAntonella Conte
Department of Neurological Sciences, University of Rome Sapienza, Viale dell Universita, 30, 00185, Rome, Italy
Exp Brain Res 186:393-9. 2008....
Psychopathological and cognitive effects of therapeutic cannabinoids in multiple sclerosis: a double-blind, placebo controlled, crossover studyMassimiliano Aragona
Sapienza University, Rome, Italy
Clin Neuropharmacol 32:41-7. 2009....
Asymmetric responses to repetitive transcranial magnetic stimulation (rTMS) over the left and right primary motor cortex in a patient with lateralized progressive limb-kinetic apraxiaFrancesca Gilio
Neurology Neurophysiopathology Unit S Pertini Hospital, Rome, Italy
Neurosci Lett 437:125-9. 2008..This asymmetric response correlated with the altered perfusion in the right hemisphere and the patient's lateralized clinical manifestations of apraxia...
Attention influences the excitability of cortical motor areas in healthy humansAntonella Conte
Department of Neurological Sciences, University of Rome La Sapienza, Viale dell Universita, 30, 00185 Rome, Italy
Exp Brain Res 182:109-17. 2007..None of the attentional conditions elicited changes in the F wave. In healthy subjects attentional processes influence the size of the MEP facilitation elicited by high-frequency rTMS and do so through premotor-to-motor connections...
Effects of repetitive transcranial magnetic stimulation on spike-and-wave dischargesAntonella Conte
Department of Neurological Sciences, University of Rome La Sapienza, Rome, Italy
Neurosci Res 57:140-2. 2007..Despite the limitations of a single case report, our neurophysiological findings suggest that 5Hz-suprathreshold rTMS delivered in short trains induces a transitory interference of the ongoing epileptic activity...
Effects of intermittent theta burst stimulation on cerebral blood flow and cerebral vasomotor reactivityFloriana Pichiorri
Department of Neurology and Psychiatry, Sapienza University, Viale dell Universita 30, 00185 Rome, Italy
J Ultrasound Med 31:1159-67. 2012..The middle cerebral artery flow velocity and vasomotor reactivity were monitored by continuous transcranial Doppler sonography. Changes in cortical excitability were tested by transcranial magnetic stimulation...
Effect of corpus callosum damage on ipsilateral motor activation in patients with multiple sclerosis: a functional and anatomical studyDelia Lenzi
Department of Neurological Sciences, University of Rome La Sapienza, Rome, Italy
Hum Brain Mapp 28:636-44. 2007..Duration of TCI was negatively correlated with activation in the iM1. Our data suggest that functional changes in iM1 in patients with MS during a motor task partially represents a consequence of loss of transcallosal inhibitory fibers...
Intracortical excitability in patients with relapsing-remitting and secondary progressive multiple sclerosisA Conte
Department of Neurological Sciences, University of Rome Sapienza, Viale dell Universita, 30, 00185, Rome, Italy
J Neurol 256:933-8. 2009..It was found that intracortical excitability as measured with TMS differs according to the clinical course of MS; it remains normal in patients with low EDSS scores and is altered in patients with high EDSS scores...
Acute and chronic effects of hypercalcaemia on cortical excitability as studied by 5 Hz repetitive transcranial magnetic stimulationElisa Iacovelli
Department of Neurological Sciences, Sapienza University of Rome, Viale dell Universita 30, 00185 Rome, Italy
J Physiol 589:1619-26. 2011....
Bladder symptoms assessed with overactive bladder questionnaire in Parkinson's diseaseElisa Iacovelli
Department of Neurological Sciences, University of Rome Sapienza, Rome, Italy
Mov Disord 25:1203-9. 2010..Our study also suggests that the OAB-q is a simple, easily administered test that can objectively evaluate bladder function in patients with PD...
Effects of transcranial magnetic stimulation on the H reflex and F wave in the hand musclesM Inghilleri
Dipartimento Scienze Neurologiche, Universita di Roma La Sapienza, Viale Universita, 30, 00185, Rome, Italy
Clin Neurophysiol 114:1096-101. 2003..In 14 healthy subjects, we studied the effects of transcranial magnetic stimulation (TMS) on the excitability of spinal motoneurons in the abductor pollicis brevis muscle (ABP), by testing the F wave and H reflex...
Acute and chronic effects of ethanol on cortical excitabilityA Conte
Department of Neurological Sciences, University of Rome Sapienza, Viale dell Universita, 30, 00185, Rome, Italy
Clin Neurophysiol 119:667-74. 2008..We designed this study to find out whether 5Hz repetitive transcranial magnetic stimulation (rTMS) would disclose changes in cortical plasticity after acute intake of ethanol and in patients with chronic alcohol consumption...
Excitatory and inhibitory after-effects after repetitive magnetic transcranial stimulation (rTMS) in normal subjectsF Gilio
Dipartimento Scienze Neurologiche, Universita di Roma La Sapienza, Viale dell Universita, 30, 00185, Rome, Italy
Exp Brain Res 176:588-93. 2007..rTMS probably elicits its after-effects on excitatory and inhibitory cortical elements through different physiological mechanisms...
Differential involvement of A-delta and A-beta fibres in neuropathic pain related to carpal tunnel syndromeA Truini
Department of Neurological Sciences, University La Sapienza, Rome, Italy
Pain 145:105-9. 2009..Our findings suggest that whereas paroxysmal pain and abnormal sensations reflect demyelination of non-nociceptive Abeta-fibres, spontaneous constant pain arises from damage to nociceptive Adelta-fibres...
Repetitive magnetic stimulation of cortical motor areas in Parkinson's disease: implications for the pathophysiology of cortical functionF Gilio
Dipartimento Scienze Neurologiche, , Rome, Italy
Mov Disord 17:467-73. 2002..The reduced rTMS-induced facilitation of MEPs in patients with Parkinson's disease reflects a decreased facilitation of the excitatory cells in the cortical motor areas...
Enhanced brain motor activity in patients with MS after a single dose of 3,4-diaminopyridineC Mainero
Section of Clinical Neurology, Department of Neurological Sciences, University of Rome La Sapienza, Italy
Neurology 62:2044-50. 2004..Although it was thought to do so by restoring conduction to demyelinated axons, recent experimental data show that aminopyridines administered at clinical doses potentiate synaptic transmission...
Spread of electrical activity at cortical level after repetitive magnetic stimulation in normal subjectsC Lorenzano
Dipartimento Scienze Neurologiche, , Viale dell'Universit, 30, 00185 Rome, Italy
Exp Brain Res 147:186-92. 2002..We conclude that the spread of EMG activity to non-target muscles depends on cortical mechanisms, mainly including changes in the excitability of the interneurones mediating intracortical inhibition...
Effects of repetitive transcranial magnetic stimulation in a patient with fixation-off sensitivityO Mecarelli
Department of Neurological Sciences, University of Rome La Sapienza, , 00185 Rome, Italy
Exp Brain Res 173:180-4. 2006..Despite the limitations of a single case report, our study confirms that low-frequency rTMS significantly reduces interictal focal epileptic activity over time...
Dissociation between cutaneous silent period and laser evoked potentials in assessing neuropathic painA Truini
Department of Neurological Sciences, La Sapienza University, Viale Università 30, Rome, Italy
Muscle Nerve 39:369-73. 2009..005) but not with CSP duration (P > 0.5). Our findings indicate that the CSP is not useful for assessing nociceptive pathway function in patients with neuropathic pain...
Mechanisms of pain in distal symmetric polyneuropathy: a combined clinical and neurophysiological studyA Truini
Department of Neurological Sciences, University La Sapienza, Rome, Italy
Pain 150:516-21. 2010..Because clinical and neurophysiological abnormalities followed similar patterns regardless of aetiology, pain should be classified and treated on mechanism-based grounds...
Physiological characterization of human muscle acetylcholine receptors from ALS patientsEleonora Palma
Dipartimento di Fisiologia e Farmacologia, Istituto Pasteur Fondazione Cenci Bolognetti, Universita Sapienza, 00185 Rome, Italy
Proc Natl Acad Sci U S A 108:20184-8. 2011..The two methods described here will be important tools for elucidating the role of muscle in ALS pathogenesis and for developing drugs to counter the effects of this disease...
Correlation between the Overactive Bladder questionnaire (OAB-q) and urodynamic data of Parkinson disease patients affected by neurogenic detrusor overactivity during antimuscarinic treatmentGiovanni Palleschi
Department of Neuroscience, Neuro-Urology Unit, Polo Pontino, University of Rome La Sapienza, Latina, Italy
Clin Neuropharmacol 29:220-9. 2006..The study suggests that this clinical tool might be used for neurogenic overactive bladder diagnosis and that it seems to be a useful outcome measure for treatments of neurogenic OAB...
Renal aplastic dysplasia and ipsilateral ectopic ureter obstructing the seminal via: a possible cause of male infertilityAntonio Carbone
Neuro urology unit, University of Rome La Sapienza Polo Pontino, Rome, Italy
Eur Urol 52:268-72. 2007..Clinical and physical assessment including transrectal ultrasound and magnetic resonance imaging are proposed as a comprehensive algorithm for the diagnostic evaluation of the pelvic cystic masses...
Myoclonus of the scapula after acute long thoracic nerve lesion: a case reportFilippo Camerota
Department of Physical Medicine and Rehabilitation, University of Rome La Sapienza, Italy
Mov Disord 21:71-3. 2006..A combination of peripheral and central mechanisms may have induced the myoclonus in this case...
Gabapentin treatment of neurogenic overactive bladderAntonio Carbone
Neuro-Urology Unit, University of Rome La Sapienza, Polo Pontino, Latina, and Department of Neuroscience, Italy
Clin Neuropharmacol 29:206-14. 2006....
DSM-IV-TR "pain disorder associated with psychological factors" as a nonhysterical form of somatizationMassimiliano Aragona
Faculty of Philosophy, University of Rome, La Sapienza, Italy
Pain Res Manag 13:13-8. 2008....
Abnormalities of motor cortex excitability preceding movement in patients with dystoniaF Gilio
Department of Neurological Sciences, University of Rome La Sapienza, , 00185 Rome, Italy
Brain 126:1745-54. 2003..In conclusion, these findings from reaction time tasks in patients with primary dystonia provide evidence of abnormal pre-movement motor cortex excitability. This abnormality is due to an altered release or running of motor programmes...
One-hertz subthreshold rTMS increases the threshold for evoking inhibition in the human motor cortexS Bagnato
Dipartimento di Scienze Neurologiche, , , 00185 Rome, Italy
Exp Brain Res 160:368-74. 2005..Hence studies investigating the after-effects of rTMS should standardize ICI levels at baseline...
Transcranial magnetic stimulation techniques in clinical investigationA Curra
Dipartimento di Scienze Neurologiche, Universita degli Studi di Roma La Sapienza, Viale dell Universita 30, 00185 Rome, Italy
Neurology 59:1851-9. 2002..These techniques are also useful in monitoring the effects of neurotrophic drugs on cortical activity. TMS applications have an important place among the investigative tools to study patients with motor disorders...
Duloxetine for the treatment of overactive bladder syndrome in multiple sclerosis: a pilot studySimone Di Rezze
Department of Neurological Sciences, La Sapienza University, Rome, Italy
Clin Neuropharmacol 35:231-4. 2012..The present study aims at establishing the efficacy and tolerability of duloxetine in the treatment of OAB in patients affected by remitting-relapsing MS and secondary progressive MS...
Randomized double-blind comparison of serotonergic (Citalopram) versus noradrenergic (Reboxetine) reuptake inhibitors in outpatients with somatoform, DSM-IV-TR pain disorderMassimiliano Aragona
Department of Psychiatry, University of Rome La Sapienza, , Italy
Eur J Pain 9:33-8. 2005..If confirmed in a larger sample, this evidence suggests that patients who are intolerant or resistant to tricyclic antidepressants, may be treated with SSRIs...
An exploratory case-control study on spinal and bulbar forms of amyotrophic lateral sclerosis in the province of RomeAlessandra Binazzi
Epidemiology Unit, Department of Occupational Medicine, Italian National Institute for Occupational Safety and Prevention, Via Alessandria 220 E, Rome, Italy
Amyotroph Lateral Scler 10:361-9. 2009..51, 90% CI 1.03-11.95). Some of the hypothesized risk factors for ALS have been found positively associated in this study, with different patterns between bulbar and spinal ALS...
Nutritional and metabolic support in patients with amyotrophic lateral sclerosisMaurizio Muscaritoli
Department of Clinical Medicine, Sapienza, University of Rome, Rome, Italy
Nutrition 28:959-66. 2012....
Transcranial direct current stimulation modulates motor responses evoked by repetitive transcranial magnetic stimulationChiara Cambieri
Department of Neurology and Psychiatry, Sapienza University of Rome, Italy
Neurosci Lett 522:167-71. 2012..In this study, we combined rTMS and tDCS to understand possible interactions between the two techniques, and investigate whether they are polarity dependent...
Isolated distal myopathy of the upper limbs associated with mitochondrial DNA depletion and polymerase gamma mutationsCarla Giordano
Department of Experimental Pathology, Sapienza University, Policlinico Umberto I, Roma, Italy
Arch Neurol 67:1144-6. 2010..To describe an unusual clinical phenotype in an adult harboring 2 compound heterozygous polymerase γ (POLG) mutations...
Bladder filling inhibits somatic spinal motoneuronesM Inghilleri
Dipartimento di Scienze Neurologiche, , 00185, Rome, Italy
Clin Neurophysiol 112:2255-60. 2001..This vesical-induced inhibition is probably mediated by the propriospinal system rather than by the diffuse noxious inhibitory control circuit...
Anatomical functional changes in a patient presenting a complex malformation of cortical developmentValentina Calistri
Department of Neurological Sciences, University of Rome La Sapienza, 00185 Rome, Italy
J Neuroimaging 14:380-4. 2004..This fMRI study highlights the compensatory role of the ipsilateral cortical pathways in hand movements in the case of a complex brain malformation that involves the main motor activation areas...
Motor cortical excitability studied with repetitive transcranial magnetic stimulation in patients with Huntington's diseaseC Lorenzano
Department of Neurological Sciences, University of Rome La Sapienza, Rome, Italy
Clin Neurophysiol 117:1677-81. 2006..SIGNIFICANCE: We suggest that depressed excitability of the motor cortex in patients with HD reflects a disease-related weakening of cortical facilitatory mechanisms...
Psychophysiological aspects of voluntary skilled movement after stroke: a follow-up studyF Fattapposta
Department of Neurology and ORL, Sapienza University of Rome, Rome, Italy
Arch Ital Biol 146:147-63. 2008..The study was also aimed at detecting any longitudinal changes in the psychophysiological pattern, as evaluated by the clinical examination and specific motility scales, that parallel motor recovery...
Modulation of viscero-somatic H-reflex during bladder filling: a possible tool in the differential diagnosis of neurogenic voiding dysfunctionsA Carbone
Department of Urology, University of Rome La Sapienza, Policlinico Umberto I, Viale del Policlinico, Rome, Italy
Eur Urol 42:281-8. 2002....
Depressed intracortical inhibition after long trains of subthreshold repetitive magnetic stimuli at low frequencyNicola Modugno
Istituto Neurologico Mediterraneo Neuromed IRCCS, Via Atinense 18, 86077 Pozzilli (IS, Italy
Clin Neurophysiol 114:2416-22. 2003..CONCLUSIONS: Subthreshold 1 Hz rTMS decreases ICI by reducing the excitability of intracortical inhibitory interneurones or by altering the electrical properties of the facilitatory chain of neurons responsible for the I waves...
Alteration of central motor excitability in a patient with hemimasticatory spasm after treatment with botulinum toxin injectionsPablo Mir
Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
Mov Disord 21:73-8. 2006..These changes can be altered by successful treatment with botulinum toxin...
Slow repetitive TMS for drug-resistant epilepsy: clinical and EEG findings of a placebo-controlled trialRoberto Cantello
Department of Clinical and Experimental Medicine, Section of Neurology, Amedeo Avogadro University, Novara, Italy
Epilepsia 48:366-74. 2007..To assess the effectiveness of slow repetitive transcranial magnetic stimulation (rTMS) as an adjunctive treatment for drug-resistant epilepsy...
