Affiliation: University of Messina
- CurrÃ² M, Gangemi C, Giunta M, Ferlazzo N, Navarra M, Ientile R, et al. Transglutaminase 2 is involved in amyloid-beta1-42-induced pro-inflammatory activation via AP1/JNK signalling pathways in THP-1 monocytes. Amino Acids. 2017;49:659-669 pubmed publisher..Our preliminary findings first suggest that TG2 up-regulation is involved in the pro-inflammatory activation of THP-1 monocytes induced by AÎ²1-42 via AP1/JNK signalling pathways. ..
- Ferlazzo N, Currò M, Zinellu A, Caccamo D, Isola G, Ventura V, et al. Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer. Int J Mol Sci. 2017;18: pubmed publisher..The frequency of p16 and MGMT methylation was around 60% in patients with either the CT/AC or TT/AA genotype. Our results suggest that hypermethylation of cancer-related genes may be affected by MTHFR polymorphisms. ..
- Russo T, Currò M, Barbera A, Caccamo D, Antonuccio P, Arena S, et al. Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. Int J Mol Sci. 2016;17: pubmed publisher..Increased expression of TG2 can be the result of chronic inflammation. TG2 overexpression can play a pivotal role in triggering and maintaining the inflammatory response in BXO patients. ..