Research Topics
Genomes and Genes | Massimo IacovielloSummaryAffiliation: University of Bari Country: Italy Publications
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Publications
Alpha- and beta-adrenergic receptor polymorphisms in hypertensive and normotensive offspringMassimo Iacoviello
Institute of Cardiology, University of Bari, Bari, Italy
J Cardiovasc Med (Hagerstown) 7:316-21. 2006..The present study aimed to verify whether these differences are associated with a different genotype distribution of functionally relevant polymorphisms of the alpha- and beta-adrenergic receptor (AR) genes...
Impaired arterial baroreflex function before nitrate-induced vasovagal syncope during head-up tilt testMassimo Iacoviello
Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
Europace 10:1170-5. 2008..The aim of this study was to evaluate arterial baroreflex control of heart rate immediately before head-up tilt test (HUT)-induced vasovagal syncope (VVS)...
Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatientsM Iacoviello
Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Bari, Italy
Curr Pharm Des 14:2686-92. 2008..It has been suggested that low thyroid hormones levels may be associated with increased mortality in patients with cardiovascular disease...
Independent role of reduced arterial baroreflex sensitivity during head-up tilt testing in predicting vasovagal syncope recurrenceMassimo Iacoviello
Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
Europace 12:1149-55. 2010..The aim of this study was to evaluate the role of arterial baroreflex sensitivity (BRS) at baseline and during head-up tilt testing (HUT) in predicting the recurrence of VVS...
Altered two-dimensional strain measures of the right ventricle in patients with Brugada syndrome and arrhythmogenic right ventricular dysplasia/cardiomyopathyMassimo Iacoviello
Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
Eur J Echocardiogr 12:773-81. 2011....
Clinical predictors of head-up tilt test outcome during the nitroglycerin phaseMassimo Iacoviello
Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
Clin Auton Res 20:167-73. 2010..Given the few data currently available, the aim of this study was to assess correlations between nitrate-induced HUT outcomes and the clinical characteristics of patients...
Ventricular repolarization dynamicity provides independent prognostic information toward major arrhythmic events in patients with idiopathic dilated cardiomyopathyMassimo Iacoviello
Institute of Cardiology, University of Bari, Bari, Italy
J Am Coll Cardiol 50:225-31. 2007..The purpose of this work was to evaluate whether ventricular repolarization dynamicity predicts major arrhythmic events in patients with idiopathic dilated cardiomyopathy (DCM)...
Beta1- and beta2-adrenergic receptor polymorphisms affect susceptibility to idiopathic dilated cardiomyopathyCinzia Forleo
Institute of Cardiology, University of Bari, Bari, Italy
J Cardiovasc Med (Hagerstown) 8:589-95. 2007..We investigated whether functionally relevant polymorphisms within the genes encoding for these receptors indicate susceptibility to idiopathic dilated cardiomyopathy (DCM)...
Ventricular asynchrony predicts a better outcome in patients with chronic heart failure receiving cardiac resynchronization therapyMaria Vittoria Pitzalis
Institute of Cardiology, University of Bari, Bari, Italy
J Am Coll Cardiol 45:65-9. 2005..The aim of this study was to evaluate whether the clinical benefit of cardiac resynchronization therapy (CRT) can be prospectively predicted by means of the baseline evaluation of left ventricular asynchrony...
Endothelin system polymorphisms in tilt test-induced vasovagal syncopeSandro Sorrentino
Emergency and Organ Transplantation Department, University of Bari, Italy
Clin Auton Res 19:347-54. 2009..As the endothelin system participates in the regulation of cardiovascular homeostasis, the aim of this study was to analyse the role of these genetic variants in influencing tilt-induced vasovagal syncope...
Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncopeSandro Sorrentino
Department, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
Auton Neurosci 155:98-103. 2010..None of the considered polymorphisms influencing sympathetic activity is a major risk factor for vasovagal syncope in Italian patients...
Nitrate-potentiated head-up tilt testing in older patients: outcomes, hemodynamic responses and prodrome recognitionPietro Guida
Cardiology Unit, Emergency and Organ Transplantation Department, University of Bari, Piazza Giulio Cesare 11, Bari, Italy
Pacing Clin Electrophysiol 33:1210-6. 2010..To compare head-up tilt testing (HUT) outcomes and hemodynamic responses, and the prevalence and correlates of prodromes, in elderly and younger patients with suspected vasovagal syncope (VVS)...
Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathyCinzia Forleo
Institute of Cardiology, University of Bari, Bari, Italy
Am J Med 117:451-8. 2004..We assessed the effects of beta-adrenergic receptor variants on heart failure in idiopathic dilated cardiomyopathy...
Independent and incremental prognostic value of endogenous ouabain in idiopathic dilated cardiomyopathyMaria Vittoria Pitzalis
Institute of Cardiology, University of Bari, Bari, Italy
Eur J Heart Fail 8:179-86. 2006..This study provides the first evidence that circulating EO is a novel, independent and incremental marker that predicts the progression of heart failure...
Enhanced reflex response to baroreceptor deactivation in subjects with tilt-induced syncopeMariavittoria Pitzalis
Institute of Cardiology, University of Bari, Italy
J Am Coll Cardiol 41:1167-73. 2003..We sought to evaluate whether changes in resting baroreflex control of heart rate are a distinctive feature of healthy subjects with a history of syncope prone to a positive tilt-test response...
Cardiac resynchronization therapy tailored by echocardiographic evaluation of ventricular asynchronyMaria Vittoria Pitzalis
Institute of Cardiology, University of Bari, Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy
J Am Coll Cardiol 40:1615-22. 2002..The value of interventricular and intraventricular echocardiographic asynchrony parameters in predicting reverse remodeling after cardiac resynchronization therapy (CRT) was investigated...
QT-interval prolongation in right precordial leads: an additional electrocardiographic hallmark of Brugada syndromeMaria Vittoria Pitzalis
Institute of Cardiology, University of Bari, Bari, Italy
J Am Coll Cardiol 42:1632-7. 2003..e., right bundle branch block, coved-type ST-segment elevation, and T-wave inversion in the right precordial leads) is characterized by a concomitant lengthening of QT intervals in the right precordial leads...
Incidence and prevalence of hypothyroidism in patients affected by chronic heart failure: role of amiodaroneVincenzo Triggiani
Endocrinology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
Endocr Metab Immune Disord Drug Targets 12:86-94. 2012..Furthermore, amiodarone, an iodine-containing antiarhythmic drug frequently used in CHF patients, is often the cause of primary hypothyroidism...
Endothelin system polymorphisms in tilt test-induced vasovagal syncopeSandro Sorrentino
Cardiology Unit, Emergency and Organ Transplantation Dept, University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy
Clin Auton Res 19:123-9. 2009..As the endothelin system participates in the regulation of cardiovascular homeostasis, the aim of this study was to analyse the role of endothelin system polymorphisms in influencing tilt-induced vasovagal syncope...
Reversibility of the endothelial dysfunction after CPAP therapy in OSAS patientsMarco Matteo Ciccone
Department of Cardiology, University of Bari, Italy
Int J Cardiol 158:383-6. 2012....
Prevalence, timing, and haemodynamic correlates of prodromes in patients with vasovagal syncope induced by head-up tilt testPietro Guida
Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
Europace 11:1221-6. 2009....
Allelic variants of natriuretic peptide receptor genes are associated with family history of hypertension and cardiovascular phenotypeMaria Vittoria Pitzalis
Institute of Cardiology, University of Bari, Bari, Italy
J Hypertens 21:1491-6. 2003..We evaluated the associations between a family history of hypertension, cardiovascular phenotype and allelic variants of Npr1 and Npr3, two candidate genes that codify for natriuretic peptide receptors...
Comparison of the effect of valsartan and lisinopril on autonomic nervous system activity in chronic heart failureElisabetta De Tommasi
Institute of Cardiology, University of Bari, Bari, Italy
Am Heart J 146:E17. 2003....
Clinical correlates of endothelial function in chronic heart failureMarco Matteo Ciccone
Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
Clin Res Cardiol 100:515-21. 2011..Brachial flow-mediated dilation (FMD) is a validated non-invasive measure of endothelial function. The aim of this study was to investigate the clinical correlates of FMD in patients with chronic heart failure (CHF)...
Shortened head-up tilting test guided by systolic pressure reductions in neurocardiogenic syncopeMariavittoria Pitzalis
Institute of Cardiology, and Innovative Technologies for Signal Detection and Processing Center, University of Bari, Bari, Italy
Circulation 105:146-8. 2002..Asymptomatic reductions in arterial pressure have been reported to occur before the onset of tilt-induced syncope. We investigated the predictive value of these reductions for a positive tilt result...
The glucocorticoid in acute decompensated heart failure: Dr Jekyll or Mr Hyde?Francesco Massari
Cardiologia UTIC, ASL BA, Altamura, Bari, Italy
Am J Emerg Med 30:517.e5-10. 2012..These data support the possible usefulness of glucocorticoids in this setting...
Increased carotid IMT in overweight and obese women affected by Hashimoto's thyroiditis: an adiposity and autoimmune linkage?Marco M Ciccone
Department of Emergency and Organ Transplantation, University of Bari, Italy
BMC Cardiovasc Disord 10:22. 2010..Hashimoto's thyroiditis is a systemic disease. The aim is to examine whether autoimmune thyroiditis and adiposity can effect carotid IMT independently of thyroid hormones and cardiovascular risk factors...
Could dilated cardiomyopathy alter the peripheral microcirculation and blood rheology?Giuseppe Cicco
Interdepartmental Center of Research on Hemorheology, Microcirculation, Oxygen Transport and Non Invasive Optical Technologies, Università degli Studi di Bari Aldo Moro, Policlinico, Piazza G Cesare, 11 70124, Bari, Italy
Adv Exp Med Biol 662:41-7. 2010..Due to the lower oxygenation and to a non-significant increase in the number of capillaries after CRT, DCM patients are at higher cardiovascular risk than healthy subjects...
