Research Topics
Genomes and GenesSpecies | Stefano IacobelliSummaryAffiliation: University of Chieti Country: Italy Publications
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Detail Information
Publications
Lack of expression of galectin-3 is associated with a poor outcome in node-negative patients with laryngeal squamous-cell carcinomaMauro Piantelli
Department of Oncology and Neurosciences, G D Annunzio University, Chieti, Italy
J Clin Oncol 20:3850-6. 2002..This study was aimed at evaluating the prognostic value of galectin-3 expression in node-negative laryngeal squamous-cell carcinoma (SCC)...
Diagnosis and treatment of disseminated intravascular coagulation: guidelines of the Italian Society for Haemostasis and Thrombosis (SISET)Marcello Di Nisio
Department of Medicine and Aging, Centre for Aging Sciences, CeSI, University GD Annunzio Foundation, Chieti, Italy
Thromb Res 129:e177-84. 2012..The diagnosis and treatment of disseminated intravascular coagulation (DIC) remain extremely controversial...
Treatment for superficial thrombophlebitis of the legMarcello Di Nisio
Department of Medicine and Aging Centre for Aging Sciences Ce S I, Internal Medicine Unit, University G d Annunzio Foundation, Chieti, Italy
Cochrane Database Syst Rev 3:CD004982. 2012..While improving or relieving the local painful symptoms, treatment should aim at preventing venous thromboembolism (VTE), which might complicate the natural history of ST. This is an update of a review first published in 2007...
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapyMarcello Di Nisio
Department of Medicine and Aging Centre for Aging Sciences Ce S I, Internal Medicine Unit, University G d Annunzio Foundation, Chieti, Italy
Cochrane Database Syst Rev 2:CD008500. 2012..The risk is further increased by chemotherapy but the safety and efficacy of primary thromboprophylaxis in cancer patients treated with chemotherapy is uncertain...
Incidental venous thromboembolism in ambulatory cancer patients receiving chemotherapyMarcello Di Nisio
Department of Medicine and Aging, Centre for Aging Sciences, University GD AnnunzioFoundation, Chieti, Italy
Thromb Haemost 104:1049-54. 2010..Further research is needed to understand the natural history of incidental thrombosis in order to develop adequate management guidelines...
Obesity, poor muscle strength, and venous thromboembolism in older persons: the InCHIANTI studyMarcello Di Nisio
Department of Medicine and Aging, Centre for Aging Sciences Ce S I, University G d Annunzio Foundation, Chieti, Italy
J Gerontol A Biol Sci Med Sci 66:320-5. 2011..This study evaluated whether obesity and poor muscle strength are associated with venous thromboembolism (VTE)...
Accuracy of diagnostic tests for clinically suspected upper extremity deep vein thrombosis: a systematic reviewM Di Nisio
Department of Medicine and Aging, Centre for Aging Sciences Ce S I, University G d Annunzio Foundation, Chieti, Italy
J Thromb Haemost 8:684-92. 2010..The aim of this systematic review was to assess whether the diagnostic accuracy of other tests for clinically suspected UEDVT is high enough to justify their use in clinical practise and to evaluate if any test can replace venography...
Thrombophilia and outcomes of assisted reproduction technologies: a systematic review and meta-analysisMarcello Di Nisio
Department of Medicine and Aging, Centre for Aging Sciences, Internal Medicine Unit, University G d Annunzio Foundation, Chieti, Italy
Blood 118:2670-8. 2011..Although case-control studies suggest that women experiencing ART failures are more frequently positive for factor V Leiden and anti-phospholipid antibodies, the evidence is inconclusive and not supported by cohort studies...
Endothelial damage of the internal carotid artery after chemoradiotherapy of the neck for a Hodgkin lymphomaMarcello Di Nisio
Department of Medicine and Aging, School of Medicine, Aging Research Center, Ce. S.I, Gabriele D'Annunzio University Foundation, Chieti-Pescara, Italy
Thromb Haemost 97:315-6. 2007
Diagnostic accuracy of D-dimer test for exclusion of venous thromboembolism: a systematic reviewM Di Nisio
Department of Medicine and Aging, School of Medicine, and Aging Research Centre, Ce S I, Gabriele D Annunzio University Foundation, Chieti Pescara, Italy
J Thromb Haemost 5:296-304. 2007..It is unknown to what extent this is due to differences in study design or patient groups, or to genuine differences between D-dimer assays...
High expression of 90K (Mac-2 BP) is associated with poor survival in node-negative breast cancer patients not receiving adjuvant systemic therapiesNicola Tinari
Department of Oncology and Neurosciences, Foundation University G d Annunzio, Chieti Pescara, Italy
Int J Cancer 124:333-8. 2009..001 for death). These findings were confirmed in the validation set. Therefore, evaluation of 90K expression may be beneficial to identify lymph-node negative breast cancer patients at lower risk of disease recurrence and death...
An epigenetic approach to pancreatic cancer treatment: the prospective role of histone deacetylase inhibitorsNicola Tinari
Department of Biomedical Sciences, University G D Annunzio, Chieti, Italy
Curr Cancer Drug Targets 12:439-52. 2012....
Meta-analysis of phase III trials of docetaxel alone or in combination with chemotherapy in metastatic breast cancerMaurizio Belfiglio
Department of Clinical Pharmacology and Epidemiology, Consorzio Mario Negri Sud, Via Nazionale 8 A, Santa Maria Imbaro, Chieti, Italy
J Cancer Res Clin Oncol 138:221-9. 2012..Aim of this work is to compare OS, TTP, and ORR in patients with MBC receiving docetaxel alone or in combination with chemotherapy using a formal meta-analysis...
Molecular mechanisms of endocrine resistance and their implication in the therapy of breast cancerMarinella Zilli
Department of Oncology and Neurosciences, University G D Annunzio Medical School, Via dei Vestini, Chieti, Italy
Biochim Biophys Acta 1795:62-81. 2009..In this review we will discuss the general principles for optimizing the choice of endocrine therapy based on an understanding of the molecular mechanisms responsible for resistance to the different anti-hormonal agents...
Long-term outcome of neoadjuvant systemic therapy for locally advanced breast cancer in routine clinical practiceDomenico Angelucci
Division of Pathology, SS Annunziata Hospital, 66013 Chieti, Italy
J Cancer Res Clin Oncol 139:269-80. 2013..The aim of this study is to evaluate the long-term outcome of patients with locally advanced breast cancer treated with neoadjuvant systemic chemotherapy (NST) in routine clinical practice...
Upstream stimulatory factor regulates constitutive expression and hormonal suppression of the 90K (Mac-2BP) proteinAntonino Grassadonia
Cell Regulation Section, Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Endocrinology 148:3507-17. 2007....
Overexpression of activated phospholipase Cγ1 is a risk factor for distant metastases in T1-T2, N0 breast cancer patients undergoing adjuvant chemotherapyRossano Lattanzio
Department of Biomedical Sciences, University G D Annunzio, Chieti, Italy Center of Excellence on Aging, Università G d Annunzio Foundation, Chieti, Italy MediaPharma s r l, Centre of Excellence on Aging, University G D Annunzio, Chieti, Italy
Int J Cancer 132:1022-31. 2013..Thus, targeting PLCγ1 pathways might represent a potential therapeutic approach for the prevention of metastatic disease in breast cancer...
A dietary tomato supplement prevents prostate cancer in TRAMP miceTania Pannellini
Department of Oncology and Neurosciences, G D Annunzio University, Chieti, Italy
Cancer Prev Res (Phila) 3:1284-91. 2010..Biochemical data disclosed an increase in serum antioxidant activity and a reduction of serum inflammation/angiogenesis biomarkers of particular importance in prostate carcinogenesis...
LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesisEnza Piccolo
MediaPharma s r l, Via Colle dell Ara, Chieti, Italy
J Mol Med (Berl) 91:83-94. 2013..e by induction of tumor VEGF and stimulation of endothelial cell tubulogenesis...
Changes of topoisomerase IIalpha expression in breast tumors after neoadjuvant chemotherapy predicts relapse-free survivalNicola Tinari
G D Annunzio University Foundation and Department of Oncology and Neurosciences, University G D Annunzio Medical School, Chieti, Italy
Clin Cancer Res 12:1501-6. 2006....
Flavonoids inhibit melanoma lung metastasis by impairing tumor cells endothelium interactionsMauro Piantelli
Department of Oncology and Neurosciences, G D Annunzio University of Chieti Pescara, Chieti, Italy
J Cell Physiol 207:23-9. 2006....
