Maria Guido

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. ncbi Viral hepatitis: Treating hepatitis C in children: an open horizon
    Maria Guido
    Department of Medical Sciences and Special Therapies, Pathology Unit, University of Padova, Via Gabelli 61, Padua, Italy
    Nat Rev Gastroenterol Hepatol 8:247-8. 2011
  2. doi Chronic viral hepatitis: the histology report
    Maria Guido
    Department of Medical Sciences and Special Therapies, University of Padova, Padova, Italy
    Dig Liver Dis 43:S331-43. 2011
  3. ncbi Chronic viral hepatitis in children: any role for the pathologist?
    Maria Guido
    Department of Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
    Gut 57:873-7. 2008
  4. ncbi Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease
    Guido Colloredo
    Liver Unit, Seriate Hospital, Bergamo, Italy
    J Hepatol 39:239-44. 2003
  5. ncbi Liver biopsy sampling in chronic viral hepatitis
    Maria Guido
    Universita degli Studi di Padova, Azienda Ospedale, Padova, Italy
    Semin Liver Dis 24:89-97. 2004
  6. doi De novo autoimmune hepatitis after liver transplantation
    Maria Guido
    Department of Medical Sciences and Special Therapies Pathology Unit, University of Padova, Padova, Italy
    Semin Liver Dis 31:71-81. 2011
  7. doi Management of chronic hepatitis C in childhood: the impact of therapy in the clinical practice during the first 2 decades
    Flavia Bortolotti
    University of Padua, Padua, Italy
    Dig Liver Dis 43:325-9. 2011
  8. ncbi Fibrosis in chronic hepatitis C acquired in infancy: is it only a matter of time?
    Maria Guido
    Dipartimento di Scienze Oncologiche and Chirurgiche, Universita degli Studi di Padova, Azienda Ospedale Padova, Padova, Italy
    Am J Gastroenterol 98:660-3. 2003
  9. ncbi Long-term course of chronic hepatitis C in children: from viral clearance to end-stage liver disease
    Flavia Bortolotti
    Clinica Medica 5, University of Padua, Padua, Italy
    Gastroenterology 134:1900-7. 2008
  10. doi Hepatitis C virus reinfection in liver transplant patients: evaluation of liver damage progression with echo-color Doppler
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Liver Transpl 14:616-24. 2008

Detail Information

Publications39

  1. ncbi Viral hepatitis: Treating hepatitis C in children: an open horizon
    Maria Guido
    Department of Medical Sciences and Special Therapies, Pathology Unit, University of Padova, Via Gabelli 61, Padua, Italy
    Nat Rev Gastroenterol Hepatol 8:247-8. 2011
    ..The results of the first controlled trial with PEG-IFN-α2a plus ribavirin are a step towards an appropriate treatment for these children...
  2. doi Chronic viral hepatitis: the histology report
    Maria Guido
    Department of Medical Sciences and Special Therapies, University of Padova, Padova, Italy
    Dig Liver Dis 43:S331-43. 2011
    ..This paper aims to provide a systematic approach to the interpretation of liver biopsies obtained in cases of chronic viral hepatitis, with the hope of helping general pathologists in their diagnostic practice...
  3. ncbi Chronic viral hepatitis in children: any role for the pathologist?
    Maria Guido
    Department of Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
    Gut 57:873-7. 2008
  4. ncbi Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease
    Guido Colloredo
    Liver Unit, Seriate Hospital, Bergamo, Italy
    J Hepatol 39:239-44. 2003
    ..In chronic viral hepatitis, liver biopsy is performed for assessing disease activity and fibrosis. In this study, we evaluated the impact of the size of liver biopsy on the grading and staging...
  5. ncbi Liver biopsy sampling in chronic viral hepatitis
    Maria Guido
    Universita degli Studi di Padova, Azienda Ospedale, Padova, Italy
    Semin Liver Dis 24:89-97. 2004
    ..Integrating earlier experience with more recently produced data indicates that a biopsy sample 2 cm or more in length containing at least 11 complete portal tracts should be reliable for grading and staging chronic viral hepatitis...
  6. doi De novo autoimmune hepatitis after liver transplantation
    Maria Guido
    Department of Medical Sciences and Special Therapies Pathology Unit, University of Padova, Padova, Italy
    Semin Liver Dis 31:71-81. 2011
    ..The final diagnosis may be a challenge in patients with recurrent hepatitis C, and requires careful clinical and pathologic assessment...
  7. doi Management of chronic hepatitis C in childhood: the impact of therapy in the clinical practice during the first 2 decades
    Flavia Bortolotti
    University of Padua, Padua, Italy
    Dig Liver Dis 43:325-9. 2011
    ..We retrospectively investigated the impact of treatment in a large cohort of children with chronic hepatitis C over the past 20 years...
  8. ncbi Fibrosis in chronic hepatitis C acquired in infancy: is it only a matter of time?
    Maria Guido
    Dipartimento di Scienze Oncologiche and Chirurgiche, Universita degli Studi di Padova, Azienda Ospedale Padova, Padova, Italy
    Am J Gastroenterol 98:660-3. 2003
    ..The natural history of chronic hepatitis C acquired in infancy is not well understood. The progression of fibrosis was analyzed in untreated children with chronic hepatitis C virus infection and no other hepatotoxic cofactors...
  9. ncbi Long-term course of chronic hepatitis C in children: from viral clearance to end-stage liver disease
    Flavia Bortolotti
    Clinica Medica 5, University of Padua, Padua, Italy
    Gastroenterology 134:1900-7. 2008
    ..The natural course of chronic hepatitis C (CHC) in children is not well understood. The aim of this study was to assess the long-term course of CHC in a large sample of otherwise healthy children...
  10. doi Hepatitis C virus reinfection in liver transplant patients: evaluation of liver damage progression with echo-color Doppler
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Liver Transpl 14:616-24. 2008
    ..In conclusion, the information obtainable from splanchnic Doppler parameters can be used to monitor the progression of liver fibrosis in transplant patients with HCV reinfection...
  11. doi A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C
    Moira Marcolongo
    Department of Histology, Microbiology, and Medical Biotechnologies, University of Padova, Padova, Italy
    Hepatology 50:1038-44. 2009
    ..Conclusion: Host genetics defined by CRS predict fibrosis progression in males with initially mild chronic hepatitis C and may become a useful parameter for prognostic evaluation and treatment decision...
  12. pmc Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B
    Giada Sebastiani
    Department of Clinical and Experimental Medicine, University of Padova, Padova 35100, Italy
    World J Gastroenterol 13:525-31. 2007
    ..To assess the performance of several non-invasive markers and of our recently proposed stepwise combination algorithms to diagnose significant fibrosis (F > or = 2 by METAVIR) and cirrhosis (F4 by METAVIR) in chronic hepatitis B (CHB)...
  13. ncbi Micronuclei and broken eggs in human liver carcinogenesis
    Maria Guido
    Department of Diagnostic Medical Sciences and Special Therapies, Pathology Unit, Universita degli Studi di Padova, Italy
    Anticancer Res 28:2507-11. 2008
    ..MNi/BE formation may result in activation of the p53-mediated cell cycle checkpoint...
  14. ncbi Liver steatosis in children with chronic hepatitis C
    Maria Guido
    Department of Oncological and Surgical Sciences Pathology Section, University of Padova, Azienda Ospedaliera, Padova, Italy
    Am J Gastroenterol 101:2611-5. 2006
    ....
  15. doi Torque Teno Virus: any pathological role in liver transplanted patients?
    Patrizia Burra
    Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
    Transpl Int 21:972-9. 2008
    ..On the basis of our data, TTV does not seem to cause liver damage following LT, although larger studies with a long-term follow up are needed to confirm these findings...
  16. doi An updated follow-up of chronic hepatitis C after three decades of observation in pediatric patients cured of malignancy
    Simone Cesaro
    Pediatric Hematology Oncology, Department of Pediatrics, University of Padova, Padova, Italy
    Pediatr Blood Cancer 55:108-12. 2010
    ..The aim of the study was to evaluate the clinical characteristics and the long-term outcome of chronic hepatitis C in a cohort of Caucasian children cured of pediatric malignancy...
  17. ncbi Effects of interferon plus ribavirin treatment on NF-kappaB, TGF-beta1, and metalloproteinase activity in chronic hepatitis C
    Maria Guido
    Section of Anatomic Pathology, Department of Oncological and Surgical Science, University of Padova, Italy
    Mod Pathol 19:1047-54. 2006
    ..Combination therapy with interferon and ribavirin affects the tissue expression of TGF-beta-1 and NF-kappaB and favors metalloproteinase activity, and may thereby modulate hepatic fibrogenetic events...
  18. doi Predicting recurrence after liver transplantation in patients with hepatocellular carcinoma exceeding the up-to-seven criteria
    Francesco D'Amico
    Hepatobiliary Surgery and Liver Transplant Unit, Department of General Surgery and Organ Transplantation, University of Padua, Padua, Italy
    Liver Transpl 15:1278-87. 2009
    ..Beyond these criteria, however, a significant proportion of patients with a good HCC biological profile had an acceptable risk of recurrence...
  19. ncbi Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study
    Flavia Bortolotti
    Fifth Medical Clinic, University of Padova, Italy
    Hepatology 43:556-62. 2006
    ..Long-term monitoring is important, as is counseling on cofactors of liver damage, such as alcohol and drug abuse...
  20. doi SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C
    Giada Sebastiani
    Venetian Institute of Molecular Medicine, Padova, Italy
    Hepatology 49:1821-7. 2009
    ..Fibroscan confirmed SAFE biopsy findings in 83.1% and 75%, respectively...
  21. pmc Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling
    Luca Fabris
    CeLiveR, Gastroenterology and Liver Transplant Unit, Ospedali Riuniti di Bergamo, Bergamo, Italy
    Am J Pathol 171:641-53. 2007
    ....
  22. ncbi Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children
    Flavia Bortolotti
    Department of Pediatrics, University of Padua, Padua, Italy
    J Pediatr 142:185-90. 2003
    ..To evaluate the clinical pattern and evolution of chronic hepatitis C in children with liver/kidney microsomal antibody type 1 autoantibodies (LKM1)...
  23. doi Hepatic expression of endocannabinoid receptors and their novel polymorphisms in primary biliary cirrhosis
    Annarosa Floreani
    Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
    J Gastroenterol 45:68-76. 2010
    ..The endocannabinoid system (EC) has emerged as a crucial mediator in a variety of pathophysiological conditions...
  24. ncbi Oxidative damage, pro-inflammatory cytokines, TGF-alpha and c-myc in chronic HCV-related hepatitis and cirrhosis
    Fabio Farinati
    Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
    World J Gastroenterol 12:2065-9. 2006
    ..To assess whether a correlation exists between oxidative DNA damage occurring in chronic HCV-related hepatitis and expression levels of pro-inflammatory cytokines, TGF-alpha and c-myc...
  25. ncbi Reversal of liver cirrhosis: a desirable clinical outcome and its pathogenic background
    Flavia Bortolotti
    Clinica Medica 5, University of Padua, Italy
    J Pediatr Gastroenterol Nutr 44:401-6. 2007
    ..Future prospects include the possibility of antifibrotic therapy to prevent fibrosis or favor its degradation...
  26. ncbi Isoniazid-related fulminant hepatic failure in a child: assessment of the native liver's early regeneration after auxiliary partial orthotopic liver transplantation
    Umberto Cillo
    Clinica Chirurgica no 1, Department of Surgical and Gastroenterological Sciences, University of Padua School of Medicine, Via Giustiniani 2, Policlinico III Piano, 35128, Padua, Italy
    Transpl Int 17:713-6. 2005
    ..In fact, the histological picture in this particular case may suggest the potential for NL recovery after INH-related FHF...
  27. doi Study of the microcirculation in hDAF transgenic rat livers xenoperfused with human blood
    Silvia Tomat
    Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, VI piano Monoblocco, Padua, Italy
    Xenotransplantation 16:83-90. 2009
    ....
  28. ncbi Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C
    Giada Sebastiani
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 35100 Padova, Italy
    J Hepatol 44:686-93. 2006
    ..Non-invasive markers have been proposed but their use is limited by diagnostic accuracy. Our aim was to increase the diagnostic performance of non-invasive markers of liver fibrosis by combining them in sequential algorithms...
  29. ncbi Neuroendocrine tumor of small bowel
    Chiara Martini
    Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Gastrointest Endosc 60:431. 2004
  30. ncbi Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma
    Anna Lisa Stefani
    Department of Histology, Microbiology and Medical Biotechnologies, University of Padova, Padova, Italy
    J Hepatol 42:728-35. 2005
    ..The aim of the study was to evaluate the in vitro and in vivo efficacy of combined gene therapy of HCC with two different MoMLV-derived retroviral vectors, an MFG- and a LXSN-derived vector, both containing HSV-TK and hIL-2...
  31. ncbi Influence of steroids on HCV recurrence after liver transplantation: A prospective study
    Marco Vivarelli
    Department of Surgery and Transplantation, University of Bologna, Italy
    J Hepatol 47:793-8. 2007
    ..To assess the effect of long-term maintenance of steroids on HCV recurrence after liver transplantation (LT), that is still controversial, a prospective multicentre trial was conducted at the centres of Bologna and Padua, Italy...
  32. ncbi Liver transplantation for HCV cirrhosis: improved survival in recent years and increased severity of recurrent disease in female recipients: results of a long term retrospective study
    Luca S Belli
    Hepatology and Abdominal Organ Transplantation Unit, Niguarda Hospital, Milan, Italy
    Liver Transpl 13:733-40. 2007
    ..The combination of a female recipient receiving an older graft emerged as a strong risk factor for a severe recurrence...
  33. ncbi Hepatitis B in children
    Flavia Bortolotti
    Hepatology 45:831; author reply 831. 2007
  34. ncbi Liver biopsy interpretation for causes of late liver allograft dysfunction
    Anthony J Demetris
    Hepatology 44:489-501. 2006
    ..A discussion of differential diagnosis is also presented...
  35. ncbi Chronic hepatitis C virus infection in childhood: clinical patterns and evolution in 224 white children
    Paloma Jara
    Hospital Infantil La Paz, Madrid, Spain
    Clin Infect Dis 36:275-80. 2003
    ..Conversely, the higher rates of fibrosis observed in older patients suggest the possibility of an insidious progression of HCV-associated liver disease...
  36. pmc Mediastinal carcinosis involving the esophagus in breast cancer: the "breast-esophagus" syndrome: report on 25 cases and guidelines for diagnosis and treatment
    Sabrina Rampado
    Istituto Oncologico Veneto IOV IRCCS, Italy
    Ann Surg 246:316-22. 2007
    ..Breast metastases of mucosal/submucosal layers of the esophagus are extremely rare: esophageal involvement is usually part of a mediastinal carcinosis...
  37. ncbi Activation of the IGF1 system characterizes cholangiocyte survival during progression of primary biliary cirrhosis
    Paolo Onori
    Department of Experimental Medicine, University of L Aquila, Italy
    J Histochem Cytochem 55:327-34. 2007
    ..This was associated and correlated with a balance of pro- and antiapoptotic proteins favoring survival rather than apoptosis, suggesting a major role of IGF1 system in promoting cholangiocyte survival...
  38. ncbi Long-term outcome of hepatitis C in children
    Flavia Bortolotti
    Hepatology 39:1455; author reply 1455-6. 2004
  39. ncbi Lack of progressive hepatic fibrosis during long-term therapy with deferiprone in subjects with transfusion-dependent beta-thalassemia
    Ian R Wanless
    Department of Laboratory Medicine and Pathobiology, Toronto General Hospital and University of Toronto, ON, Canada
    Blood 100:1566-9. 2002
    ..This analysis of the largest collection of liver biopsies reported to date in patients receiving deferiprone demonstrates no evidence of deferiprone-induced progression of hepatic fibrosis during long-term therapy...